UA40663C2 - Тверда фармацевтична композиція з регульованим вивільненням лікарського засобу для орального вживання - Google Patents

Тверда фармацевтична композиція з регульованим вивільненням лікарського засобу для орального вживання

Info

Publication number
UA40663C2
UA40663C2 UA97073814A UA97073814A UA40663C2 UA 40663 C2 UA40663 C2 UA 40663C2 UA 97073814 A UA97073814 A UA 97073814A UA 97073814 A UA97073814 A UA 97073814A UA 40663 C2 UA40663 C2 UA 40663C2
Authority
UA
Ukraine
Prior art keywords
pharmaceutical composition
oral administration
solid pharmaceutical
controlled release
composition adapted
Prior art date
Application number
UA97073814A
Other languages
English (en)
Russian (ru)
Inventor
Невілл У. Борд
Невилл У. Борд
Елан Ф. Кармоуді
Элан Ф. Кармоуди
Лайєм К. Філі
Лайем К. Фили
Брайєн К. Уізерс
Брайен К. Уизерс
Original Assignee
Ебботт Лабораторіз
Ебботт Лабораториз
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=24298013&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=UA40663(C2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Ебботт Лабораторіз, Ебботт Лабораториз filed Critical Ебботт Лабораторіз
Publication of UA40663C2 publication Critical patent/UA40663C2/uk

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/165Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404Indoles, e.g. pindolol
    • A61K31/4045Indole-alkylamines; Amides thereof, e.g. serotonin, melatonin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41641,3-Diazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • A61K31/55131,4-Benzodiazepines, e.g. diazepam or clozapine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2013Organic compounds, e.g. phospholipids, fats
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/02Local antiseptics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Винахід стосується форми перорального дозування контрольованого поступового вивільнення для щонайменш одного малорозчинного основного лікарського засобу, що дозволить змінити режим щоденного дозування. Тверда фармацевтична композиція з регульованим вивільненням лікарського засобу для перорального вживання, що включає водорозчинну сіль альгінової кислоти, причому вона додатково містить терапевтично ефективну кількість, принаймні, одного лікарського засобу, що має розчинність у воді менше, ніж 1 частина на ЗО частин води, і ефективну кількість органічної карбонової кислоти для полегшення розчинення лікарського засобу.
UA97073814A 1995-12-19 1996-11-25 Тверда фармацевтична композиція з регульованим вивільненням лікарського засобу для орального вживання UA40663C2 (uk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/574,877 US5705190A (en) 1995-12-19 1995-12-19 Controlled release formulation for poorly soluble basic drugs
PCT/US1996/018960 WO1997022335A1 (en) 1995-12-19 1996-11-25 A controlled release formulation for poorly soluble basic drugs

Publications (1)

Publication Number Publication Date
UA40663C2 true UA40663C2 (uk) 2001-08-15

Family

ID=24298013

Family Applications (1)

Application Number Title Priority Date Filing Date
UA97073814A UA40663C2 (uk) 1995-12-19 1996-11-25 Тверда фармацевтична композиція з регульованим вивільненням лікарського засобу для орального вживання

Country Status (26)

Country Link
US (1) US5705190A (uk)
EP (1) EP0799028B1 (uk)
JP (1) JP3292732B2 (uk)
KR (1) KR100632187B1 (uk)
CN (1) CN1131027C (uk)
AR (1) AR004391A1 (uk)
AT (2) ATE170744T1 (uk)
AU (1) AU701268B2 (uk)
CA (1) CA2209714C (uk)
CZ (1) CZ289158B6 (uk)
DE (2) DE29624506U1 (uk)
DK (1) DK0799028T3 (uk)
ES (1) ES2122810T3 (uk)
HU (1) HUP9800516A3 (uk)
IL (1) IL121275A (uk)
IT (1) ITMI20050383U1 (uk)
NZ (1) NZ323332A (uk)
PL (1) PL186696B1 (uk)
PT (1) PT103379B (uk)
RO (1) RO117501B1 (uk)
RU (1) RU2142793C1 (uk)
TR (1) TR199800777T2 (uk)
TW (1) TW429154B (uk)
UA (1) UA40663C2 (uk)
WO (1) WO1997022335A1 (uk)
ZA (1) ZA9610110B (uk)

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