UA41280C2 - OXAZOLIDINONES, THEIR SALTS, THE METHOD OF THEIR PREPARATION, THE PHARMACEUTICAL PREPARATION AND THE METHOD OF OBTAINING IT - Google Patents

OXAZOLIDINONES, THEIR SALTS, THE METHOD OF THEIR PREPARATION, THE PHARMACEUTICAL PREPARATION AND THE METHOD OF OBTAINING IT

Info

Publication number
UA41280C2
UA41280C2 UA94005166A UA94005166A UA41280C2 UA 41280 C2 UA41280 C2 UA 41280C2 UA 94005166 A UA94005166 A UA 94005166A UA 94005166 A UA94005166 A UA 94005166A UA 41280 C2 UA41280 C2 UA 41280C2
Authority
UA
Ukraine
Prior art keywords
preparation
salts
oxazolidinones
obtaining
formula
Prior art date
Application number
UA94005166A
Other languages
Russian (ru)
Ukrainian (uk)
Inventor
Петер РАДДАТЦ
Йоахім Ганте
Йоахим ГАНТЕ
Хорст Юрачік
Ханнс Вурцигєр
Хєльмут Прюхєр
Сабіне Бернотат-Данєловскі
Гвідо Мєльцер
Original Assignee
Мерк Патент Гмбх
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Мерк Патент Гмбх filed Critical Мерк Патент Гмбх
Publication of UA41280C2 publication Critical patent/UA41280C2/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/18—Oxygen atoms
    • C07D263/20—Oxygen atoms attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10—Spiro-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Новые соединения, в качестве антагонистов адгезивных рецепторов, способ их получения, фармкомпозициях на их основе и способ ее получения Новые соединения формулы I где R1, Х и У имеют значения, данные в п.1 формулы, а также их соли, препятствуют соединению фибриногенов с фибриногенными рецепторами и могут использоваться для лечения тромбозов, апоплексии, инфаркта миокарда, воспалений, артериосклероза, остеопороза, а также опухолей.New compounds, as antagonists of adhesive receptors, a method for their preparation, pharmaceutical compositions based on them and a method for its preparation New compounds of formula I where R1, X and Y have the meanings given in claim 1 of the formula, as well as their salts, prevent the combination of fibrinogens with fibrinogen receptors and can be used to treat thrombosis, apoplexy, myocardial infarction, inflammation, arteriosclerosis, osteoporosis, and tumors.

UA94005166A 1993-05-01 1994-04-07 OXAZOLIDINONES, THEIR SALTS, THE METHOD OF THEIR PREPARATION, THE PHARMACEUTICAL PREPARATION AND THE METHOD OF OBTAINING IT UA41280C2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4314378 1993-05-01
DE4405633A DE4405633A1 (en) 1993-05-01 1994-02-22 Adhesion receptor antagonists

Publications (1)

Publication Number Publication Date
UA41280C2 true UA41280C2 (en) 2001-09-17

Family

ID=6486893

Family Applications (1)

Application Number Title Priority Date Filing Date
UA94005166A UA41280C2 (en) 1993-05-01 1994-04-07 OXAZOLIDINONES, THEIR SALTS, THE METHOD OF THEIR PREPARATION, THE PHARMACEUTICAL PREPARATION AND THE METHOD OF OBTAINING IT

Country Status (4)

Country Link
DE (2) DE4405633A1 (en)
TW (1) TW336224B (en)
UA (1) UA41280C2 (en)
ZA (1) ZA942973B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4429461A1 (en) * 1994-08-19 1996-02-22 Merck Patent Gmbh Adhesion receptor antagonists
DE4439846A1 (en) * 1994-11-08 1996-05-09 Merck Patent Gmbh Adhesion receptor antagonists

Also Published As

Publication number Publication date
ZA942973B (en) 1995-01-18
DE4405633A1 (en) 1994-11-03
TW336224B (en) 1998-07-11
DE59408441D1 (en) 1999-08-05

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