UA48960C2 - Трициклічні діазепіни, спосіб їх одержання і спосіб лікування з використанням трициклічних діазепінів - Google Patents

Трициклічні діазепіни, спосіб їх одержання і спосіб лікування з використанням трициклічних діазепінів

Info

Publication number
UA48960C2
UA48960C2 UA97084248A UA97084248A UA48960C2 UA 48960 C2 UA48960 C2 UA 48960C2 UA 97084248 A UA97084248 A UA 97084248A UA 97084248 A UA97084248 A UA 97084248A UA 48960 C2 UA48960 C2 UA 48960C2
Authority
UA
Ukraine
Prior art keywords
tricyclic diazepines
tricyclic
preparation
treatment
diazepines
Prior art date
Application number
UA97084248A
Other languages
English (en)
Russian (ru)
Inventor
Аранапакам Мудумбай Венкатесан
Джей Дональд Олбрайт
Джордж Теодор Гросу
Original Assignee
Амерікан Ціанамід Компані
Американ Цианамид Компани
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Амерікан Ціанамід Компані, Американ Цианамид Компани filed Critical Амерікан Ціанамід Компані
Publication of UA48960C2 publication Critical patent/UA48960C2/uk

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/06—Antiabortive agents; Labour repressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Diabetes (AREA)
  • Neurology (AREA)
  • Endocrinology (AREA)
  • Biomedical Technology (AREA)
  • Cardiology (AREA)
  • Neurosurgery (AREA)
  • Reproductive Health (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Obesity (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Psychiatry (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Emergency Medicine (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Описані похідні трициклічних діазепінів формули (І), де визначення А, В, D, Е, F і Ζ подані в описі, які проявляють активність антагоністів вазопресину і окситоцину, та спосіб їх одержання. Описано використання трициклічних діазепінів формули (І) як активної сполуки в фармацевтичній композиції і спосіб лікування ссавця з використаннням сполук формули (І).
UA97084248A 1995-01-17 1996-01-16 Трициклічні діазепіни, спосіб їх одержання і спосіб лікування з використанням трициклічних діазепінів UA48960C2 (uk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/373,125 US5521173A (en) 1995-01-17 1995-01-17 Tricyclic benzazepine vasopressin antagonists
PCT/US1996/000515 WO1996022292A1 (en) 1995-01-17 1996-01-16 Tricyclic vasopressin antagonists

Publications (1)

Publication Number Publication Date
UA48960C2 true UA48960C2 (uk) 2002-09-16

Family

ID=23471074

Family Applications (1)

Application Number Title Priority Date Filing Date
UA97084248A UA48960C2 (uk) 1995-01-17 1996-01-16 Трициклічні діазепіни, спосіб їх одержання і спосіб лікування з використанням трициклічних діазепінів

Country Status (23)

Country Link
US (2) US5521173A (uk)
EP (1) EP0805813B1 (uk)
JP (2) JP4156664B2 (uk)
CN (1) CN1052725C (uk)
AR (1) AR002021A1 (uk)
AT (1) ATE217625T1 (uk)
AU (1) AU707881B2 (uk)
BR (1) BR9607177A (uk)
CA (1) CA2210708C (uk)
CZ (1) CZ224797A3 (uk)
DE (1) DE69621225T2 (uk)
DK (1) DK0805813T3 (uk)
EA (1) EA000056B1 (uk)
ES (1) ES2175066T3 (uk)
HU (1) HUP9702459A3 (uk)
IL (1) IL116774A (uk)
MX (1) MX9705414A (uk)
NZ (1) NZ301198A (uk)
PT (1) PT805813E (uk)
TW (1) TW472056B (uk)
UA (1) UA48960C2 (uk)
WO (1) WO1996022292A1 (uk)
ZA (1) ZA96303B (uk)

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Also Published As

Publication number Publication date
MX9705414A (es) 1997-11-29
AU4656696A (en) 1996-08-07
US5521173A (en) 1996-05-28
JPH11500424A (ja) 1999-01-12
JP2008069176A (ja) 2008-03-27
EA000056B1 (ru) 1998-04-30
CN1178532A (zh) 1998-04-08
WO1996022292A1 (en) 1996-07-25
ZA96303B (en) 1997-07-15
BR9607177A (pt) 1997-11-11
HUP9702459A3 (en) 2000-08-28
TW472056B (en) 2002-01-11
PT805813E (pt) 2002-10-31
DK0805813T3 (da) 2002-08-05
IL116774A (en) 2000-12-06
JP4156664B2 (ja) 2008-09-24
AR002021A1 (es) 1998-01-07
HK1003891A1 (en) 1998-11-13
EP0805813A1 (en) 1997-11-12
EA199700118A1 (ru) 1997-12-30
CZ224797A3 (cs) 1998-03-18
IL116774A0 (en) 1996-05-14
CA2210708A1 (en) 1996-07-25
CA2210708C (en) 2005-05-24
CN1052725C (zh) 2000-05-24
HUP9702459A2 (hu) 1998-05-28
DE69621225T2 (de) 2002-11-14
ATE217625T1 (de) 2002-06-15
EP0805813B1 (en) 2002-05-15
NZ301198A (en) 1999-08-30
ES2175066T3 (es) 2002-11-16
AU707881B2 (en) 1999-07-22
DE69621225D1 (de) 2002-06-20
US5780471A (en) 1998-07-14

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