UA74404C2 - Производные пиридинзамещенных пиразолопиридинов - Google Patents

Производные пиридинзамещенных пиразолопиридинов

Info

Publication number
UA74404C2
UA74404C2 UA2003065752A UA200365752A UA74404C2 UA 74404 C2 UA74404 C2 UA 74404C2 UA 2003065752 A UA2003065752 A UA 2003065752A UA 200365752 A UA200365752 A UA 200365752A UA 74404 C2 UA74404 C2 UA 74404C2
Authority
UA
Ukraine
Prior art keywords
pyrazolopyridine
substituted derivatives
pyridine substituted
diseases
treating
Prior art date
Application number
UA2003065752A
Other languages
English (en)
Ukrainian (uk)
Inventor
Йоханнес-Петер Шташ
Ахім Фойрер
Ахим Фойрер
Штефан Вайганд
Ельке Шталь
Дітмар Флубахер
Крістіна Алонсо-Алія
Франк Вундер
Дітер Ланг
Дитер Ланг
Клаус ДЕМБОВСКИ
Александер Штрауб
Елізабет Перзборн
Элизабет Перзборн
Original Assignee
Баєр Акціенгезельшафт
Байер Акциенгезелльшафт
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Баєр Акціенгезельшафт, Байер Акциенгезелльшафт filed Critical Баєр Акціенгезельшафт
Priority claimed from PCT/EP2001/012969 external-priority patent/WO2002042301A1/de
Publication of UA74404C2 publication Critical patent/UA74404C2/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Настоящее изобретение касается новых производных пиразолопиридина формулы (І), в которой R1 4-означает пиридинил 3-или пиридинил, R2 означает водород, NH2 или галоген, а также солей, изомеров и гидратов этих соединений, которые предназначены для использования как стимуляторы растворимой гуанилатциклазы и лекарственных средств для лечения заболеваний кровообращения сердца, гипертонии, тромбоэмболических болезней, ишемии, сексуальной дисфункции, заболеваний центральной нервной системы, а также как противовоспалительное средство.  
UA2003065752A 2000-11-22 2001-11-09 Производные пиридинзамещенных пиразолопиридинов UA74404C2 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE10057753 2000-11-22
DE10131987A DE10131987A1 (de) 2000-11-22 2001-07-02 Neue Pyridin-substituierte Pyrazolopyridinderivate
PCT/EP2001/012969 WO2002042301A1 (de) 2000-11-22 2001-11-09 Neue pyridin-substituierte pyrazolopyridinderivate

Publications (1)

Publication Number Publication Date
UA74404C2 true UA74404C2 (ru) 2005-12-15

Family

ID=7664122

Family Applications (1)

Application Number Title Priority Date Filing Date
UA2003065752A UA74404C2 (ru) 2000-11-22 2001-11-09 Производные пиридинзамещенных пиразолопиридинов

Country Status (12)

Country Link
KR (1) KR20030065519A (ru)
DE (2) DE10131987A1 (ru)
DO (1) DOP2001000291A (ru)
EC (1) ECSP034616A (ru)
GT (1) GT200100235A (ru)
HN (1) HN2001000261A (ru)
MY (1) MY127212A (ru)
PE (1) PE20020581A1 (ru)
RU (1) RU2003118584A (ru)
SV (1) SV2003000743A (ru)
UA (1) UA74404C2 (ru)
ZA (1) ZA200303887B (ru)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102485724B (zh) * 2010-12-06 2015-08-12 中国人民解放军军事医学科学院毒物药物研究所 取代噻吩基吡唑并吡啶类化合物及其医药用途
ES2603028T3 (es) 2011-11-25 2017-02-23 Adverio Pharma Gmbh Procedimiento para la preparación de (Z)-alfa-fluoro-beta-amino-acrilaldehídos sustituidos
EP3525779B1 (de) * 2016-10-11 2024-06-05 Bayer Pharma Aktiengesellschaft Kombination enthaltend den sgc stimulator vericuguat und den mineralcorticoid-rezeptor-antagonist finerenone

Also Published As

Publication number Publication date
ECSP034616A (es) 2003-06-25
MY127212A (en) 2006-11-30
RU2003118584A (ru) 2004-12-20
PE20020581A1 (es) 2002-07-13
GT200100235A (es) 2002-06-25
KR20030065519A (ko) 2003-08-06
DE10131987A1 (de) 2002-05-23
DOP2001000291A (es) 2002-12-15
HN2001000261A (es) 2002-01-30
ZA200303887B (en) 2004-06-21
SV2003000743A (es) 2003-01-13
DE50106655D1 (de) 2005-08-04

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