UA75425C2 - Piperazine oxime derivatives with antagonistic activity to nk-1 receptor, use thereof, a pharmaceutical composition based thereon, a method for producing and a method for producing intermediary compounds - Google Patents

Piperazine oxime derivatives with antagonistic activity to nk-1 receptor, use thereof, a pharmaceutical composition based thereon, a method for producing and a method for producing intermediary compounds Download PDF

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Publication number
UA75425C2
UA75425C2 UA2004020930A UA2004020930A UA75425C2 UA 75425 C2 UA75425 C2 UA 75425C2 UA 2004020930 A UA2004020930 A UA 2004020930A UA 2004020930 A UA2004020930 A UA 2004020930A UA 75425 C2 UA75425 C2 UA 75425C2
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ylmethyl
disorders
indol
compounds
bis
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UA2004020930A
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English (en)
Ukrainian (uk)
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Maarsevein Yan G Van
Martinus T M Tulp
Andrew K Mccriri
Bakker Vouter E Ivema
Gain K A K Koolen
Arnoldus G Y Gerremans
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    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
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    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
UA2004020930A 2001-07-09 2002-03-07 Piperazine oxime derivatives with antagonistic activity to nk-1 receptor, use thereof, a pharmaceutical composition based thereon, a method for producing and a method for producing intermediary compounds UA75425C2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP01202631 2001-07-09
PCT/EP2002/007472 WO2003006459A1 (en) 2001-07-09 2002-07-03 Piperazine oxime derivatives having nk-1 receptor antagonistic activity

Publications (1)

Publication Number Publication Date
UA75425C2 true UA75425C2 (en) 2006-04-17

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UA2004020930A UA75425C2 (en) 2001-07-09 2002-03-07 Piperazine oxime derivatives with antagonistic activity to nk-1 receptor, use thereof, a pharmaceutical composition based thereon, a method for producing and a method for producing intermediary compounds

Country Status (25)

Country Link
US (1) US7094779B2 (de)
EP (1) EP1406894B1 (de)
JP (1) JP3765543B2 (de)
KR (1) KR100900889B1 (de)
CN (1) CN1223591C (de)
AR (1) AR034722A1 (de)
AT (1) ATE285407T1 (de)
AU (1) AU2002333229B2 (de)
BR (1) BR0210080A (de)
CA (1) CA2446726A1 (de)
DE (1) DE60202371T2 (de)
DK (1) DK1406894T3 (de)
ES (1) ES2230521T3 (de)
HR (1) HRP20030912A2 (de)
HU (1) HUP0401093A3 (de)
IL (2) IL158728A0 (de)
MX (1) MXPA04000230A (de)
NO (1) NO20040065L (de)
PL (1) PL366841A1 (de)
PT (1) PT1406894E (de)
RU (1) RU2273639C2 (de)
SI (1) SI1406894T1 (de)
UA (1) UA75425C2 (de)
WO (1) WO2003006459A1 (de)
ZA (1) ZA200308782B (de)

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US7498342B2 (en) 2004-06-17 2009-03-03 Plexxikon, Inc. Compounds modulating c-kit activity
KR100616099B1 (ko) * 2004-09-20 2006-08-28 한국과학기술연구원 Ｔ-타입 칼슘채널 길항제로 유효한 신규 피페라지닐알킬이소옥사졸 유도체
US7846941B2 (en) 2005-05-17 2010-12-07 Plexxikon, Inc. Compounds modulating c-kit and c-fms activity and uses therefor
UA95244C2 (ru) 2005-06-22 2011-07-25 Плексикон, Инк. Соединения и способ модулирования активности киназ, и показания для их применения
WO2008063888A2 (en) 2006-11-22 2008-05-29 Plexxikon, Inc. Compounds modulating c-fms and/or c-kit activity and uses therefor
WO2008104942A2 (en) * 2007-02-28 2008-09-04 Ranbaxy Laboratories Limited Muscarinic receptor antagonists
WO2009012283A1 (en) 2007-07-17 2009-01-22 Plexxikon Inc. Compounds and methods for kinase modulation, and indications therefor
MY172424A (en) 2009-04-03 2019-11-25 Hoffmann La Roche Propane- i-sulfonic acid {3- (4-chloro-phenyl)-1h-pyrrolo [2, 3-b] pyridine-3-carconyl] -2, 4-difluoro-phenyl} -amide compositions and uses thereof
CN106220623A (zh) 2009-11-06 2016-12-14 普莱希科公司 用于激酶调节的化合物和方法及其适应症
US9624213B2 (en) 2011-02-07 2017-04-18 Plexxikon Inc. Compounds and methods for kinase modulation, and indications therefor
AR085279A1 (es) 2011-02-21 2013-09-18 Plexxikon Inc Formas solidas de {3-[5-(4-cloro-fenil)-1h-pirrolo[2,3-b]piridina-3-carbonil]-2,4-difluor-fenil}-amida del acido propano-1-sulfonico
US9150570B2 (en) 2012-05-31 2015-10-06 Plexxikon Inc. Synthesis of heterocyclic compounds
CN104958297A (zh) * 2015-06-03 2015-10-07 周玉梅 一种用于麻醉镇静催眠的药物组合物及其应用
CN110615774B (zh) * 2019-09-19 2022-11-11 安徽中医药大学 具有抗炎活性的苄基哌嗪类化合物、制法及医药用途
JP7658740B2 (ja) 2020-12-07 2025-04-08 三星電子株式会社 共重合体、ならびに当該共重合体を用いるエレクトロルミネッセンス素子材料およびエレクトロルミネッセンス素子

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