UA75565C2 - Фармацевтична сполука для стимулювання ангіогенезу (варіанти), фармацевтична сполука для інгібування ангіогенезу (варіанти) та спосіб модулювання ангіогенезу з їх використанням - Google Patents

Фармацевтична сполука для стимулювання ангіогенезу (варіанти), фармацевтична сполука для інгібування ангіогенезу (варіанти) та спосіб модулювання ангіогенезу з їх використанням Download PDF

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Publication number
UA75565C2
UA75565C2 UA2000127086A UA2000127086A UA75565C2 UA 75565 C2 UA75565 C2 UA 75565C2 UA 2000127086 A UA2000127086 A UA 2000127086A UA 2000127086 A UA2000127086 A UA 2000127086A UA 75565 C2 UA75565 C2 UA 75565C2
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UA
Ukraine
Prior art keywords
protein
angiogenesis
item
tissue
pharmaceutical compound
Prior art date
Application number
UA2000127086A
Other languages
English (en)
Russian (ru)
Ukrainian (uk)
Inventor
Дейвід Е. Череш
Брайен Елісейрі
Памела Л. Шварцберг
Original Assignee
Scripps Research Inst
Us Government
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scripps Research Inst, Us Government filed Critical Scripps Research Inst
Publication of UA75565C2 publication Critical patent/UA75565C2/uk

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/12Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00Uses of viruses
    • C12N2799/02Uses of viruses as vector
    • C12N2799/021Uses of viruses as vector for the expression of a heterologous nucleic acid

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Rheumatology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Cardiology (AREA)
  • Microbiology (AREA)
  • Oncology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Ophthalmology & Optometry (AREA)
  • Urology & Nephrology (AREA)
  • Pain & Pain Management (AREA)
  • Vascular Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Enzymes And Modification Thereof (AREA)
UA2000127086A 1998-05-29 1999-05-28 Фармацевтична сполука для стимулювання ангіогенезу (варіанти), фармацевтична сполука для інгібування ангіогенезу (варіанти) та спосіб модулювання ангіогенезу з їх використанням UA75565C2 (uk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US8722098P 1998-05-29 1998-05-29
PCT/US1999/011780 WO1999061590A1 (en) 1998-05-29 1999-05-28 Methods and compositions useful for modulation of angiogenesis using tyrosine kinase src

Publications (1)

Publication Number Publication Date
UA75565C2 true UA75565C2 (uk) 2006-05-15

Family

ID=22203825

Family Applications (1)

Application Number Title Priority Date Filing Date
UA2000127086A UA75565C2 (uk) 1998-05-29 1999-05-28 Фармацевтична сполука для стимулювання ангіогенезу (варіанти), фармацевтична сполука для інгібування ангіогенезу (варіанти) та спосіб модулювання ангіогенезу з їх використанням

Country Status (23)

Country Link
US (1) US7585841B2 (de)
EP (1) EP1082415B1 (de)
JP (1) JP4806487B2 (de)
KR (1) KR20010085261A (de)
CN (1) CN1304567C (de)
AT (1) ATE506073T1 (de)
AU (1) AU762955C (de)
BR (1) BR9910787A (de)
CA (1) CA2330025C (de)
CZ (1) CZ302918B6 (de)
DE (1) DE69943374D1 (de)
DK (1) DK1082415T3 (de)
ES (1) ES2361659T3 (de)
HU (1) HU227985B1 (de)
MX (1) MXPA00011821A (de)
NO (1) NO327610B1 (de)
PT (1) PT1082415E (de)
RU (1) RU2222342C2 (de)
SK (1) SK287330B6 (de)
TR (1) TR200100430T2 (de)
UA (1) UA75565C2 (de)
WO (1) WO1999061590A1 (de)
ZA (1) ZA200007321B (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MXPA00011821A (es) * 1998-05-29 2004-07-30 Scripps Research Inst Metodos y composiciones utiles para la modulacion de la angiogenesis usando tirosina-cinasa src.
US20030130209A1 (en) * 1999-12-22 2003-07-10 Cheresh David A. Method of treatment of myocardial infarction
US6685938B1 (en) * 1998-05-29 2004-02-03 The Scripps Research Institute Methods and compositions useful for modulation of angiogenesis and vascular permeability using SRC or Yes tyrosine kinases
US6297258B1 (en) * 1998-09-29 2001-10-02 American Cyanamid Company Substituted 3-cyanoquinolines
EP1250155B1 (de) * 1999-12-22 2008-04-16 The Scripps Research Institute Modulatoren und inhibitoren von angiogenese und vaskulärer durchlässigkeit
US7485414B2 (en) 2002-08-30 2009-02-03 Rigel Pharmaceuticals, Inc. Modulators of angiogenesis
US20080280987A1 (en) * 2006-08-31 2008-11-13 Desai Neil P Methods of inhibiting angiogenesis and treating angiogenesis-associated diseases
WO2008054792A2 (en) * 2006-10-31 2008-05-08 University Of Toledo Na+/k+-atpase-specific peptide inhibitors/activators of src and src family kinases
DE102007037008B4 (de) * 2007-08-06 2015-09-10 Siemens Aktiengesellschaft Diagnosesubstanz zur Anwendung in einem Verfahren zur Bestimmung der Aggressivität eines Prostatatumors
WO2010105172A1 (en) 2009-03-13 2010-09-16 Abraxis Bioscience, Llc Combination therapy with thiocolchicine derivatives

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5264618A (en) * 1990-04-19 1993-11-23 Vical, Inc. Cationic lipids for intracellular delivery of biologically active molecules
AU7432496A (en) * 1995-10-13 1998-05-11 Regents Of The University Of Minnesota Consolidated ligands with increased affinities and methods of use thereof
US6335010B1 (en) * 1996-11-08 2002-01-01 University Of California At San Diego Gene therapy in coronary angioplasty and bypass
MXPA00011821A (es) * 1998-05-29 2004-07-30 Scripps Research Inst Metodos y composiciones utiles para la modulacion de la angiogenesis usando tirosina-cinasa src.
GB2341182A (en) * 1998-09-01 2000-03-08 Yamanouchi Uk Ltd Protein comprising amino acid sequences having SH3 domain binding activity and nuclear localisation activity

Also Published As

Publication number Publication date
CA2330025A1 (en) 1999-12-02
CA2330025C (en) 2009-03-17
EP1082415A4 (de) 2003-07-09
ZA200007321B (en) 2002-03-08
SK18112000A3 (sk) 2001-09-11
EP1082415A1 (de) 2001-03-14
AU762955C (en) 2005-03-24
NO327610B1 (no) 2009-08-31
HK1041289A1 (en) 2002-07-05
SK287330B6 (sk) 2010-07-07
WO1999061590A1 (en) 1999-12-02
US7585841B2 (en) 2009-09-08
US20060009412A1 (en) 2006-01-12
HUP0102614A2 (hu) 2001-11-28
JP4806487B2 (ja) 2011-11-02
PT1082415E (pt) 2011-07-04
DK1082415T3 (da) 2011-06-14
MXPA00011821A (es) 2004-07-30
WO1999061590A9 (en) 2000-03-09
CZ302918B6 (cs) 2012-01-18
ATE506073T1 (de) 2011-05-15
ES2361659T3 (es) 2011-06-21
KR20010085261A (ko) 2001-09-07
BR9910787A (pt) 2001-10-30
HU227985B1 (en) 2012-07-30
NO20006026L (no) 2001-01-24
CN1304567C (zh) 2007-03-14
JP2002516344A (ja) 2002-06-04
RU2222342C2 (ru) 2004-01-27
TR200100430T2 (tr) 2002-05-21
AU4101399A (en) 1999-12-13
EP1082415B1 (de) 2011-04-20
CZ20004435A3 (en) 2001-06-13
NO20006026D0 (no) 2000-11-28
HUP0102614A3 (en) 2005-11-28
DE69943374D1 (de) 2011-06-01
AU762955B2 (en) 2003-07-10
CN1319131A (zh) 2001-10-24

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