UA77403C2 - Use of gaboxadol as gaba enhancer for treatment of disorders relating to reduced neurosteroid activity - Google Patents

Use of gaboxadol as gaba enhancer for treatment of disorders relating to reduced neurosteroid activity Download PDF

Info

Publication number: UA77403C2
Authority: UA; Ukraine
Prior art keywords: gaba; activity; treatment; progesterone; receptors
Prior art date: 2000-11-20

Application number

UA2003054188A

Other languages

English (en)

Ukrainian (uk)

Original Assignee

Lundbeck & Co As H

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-11-20

Filing date

2001-11-20

Publication date

2006-12-15

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8159857&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=UA77403(C2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2001-11-20 Application filed by Lundbeck & Co As H filed Critical Lundbeck & Co As H

2006-12-15 Publication of UA77403C2 publication Critical patent/UA77403C2/uk

Links

208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title claims abstract description 25
208000035475 disorder Diseases 0.000 title claims abstract description 15
ZXRVKCBLGJOCEE-UHFFFAOYSA-N Gaboxadol Chemical compound C1NCCC2=C1ONC2=O ZXRVKCBLGJOCEE-UHFFFAOYSA-N 0.000 title claims description 3
229950004346 gaboxadol Drugs 0.000 title claims description 3
230000000694 effects Effects 0.000 title abstract description 23
239000003623 enhancer Substances 0.000 title abstract description 4
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BTCSSZJGUNDROE-UHFFFAOYSA-N gamma-aminobutyric acid Chemical compound NCCCC(O)=O BTCSSZJGUNDROE-UHFFFAOYSA-N 0.000 description 33
RJKFOVLPORLFTN-LEKSSAKUSA-N Progesterone Chemical compound C1CC2=CC(=O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H](C(=O)C)[C@@]1(C)CC2 RJKFOVLPORLFTN-LEKSSAKUSA-N 0.000 description 32
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QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
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SRPNQDXRVRCTNK-UHFFFAOYSA-N pivagabine Chemical compound CC(C)(C)C(=O)NCCCC(O)=O SRPNQDXRVRCTNK-UHFFFAOYSA-N 0.000 description 1
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Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4172—Imidazole-alkanecarboxylic acids, e.g. histidine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
- A—HUMAN NECESSITIES
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- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/4535—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a heterocyclic ring having sulfur as a ring hetero atom, e.g. pizotifen
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- A—HUMAN NECESSITIES
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Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Chemical Kinetics & Catalysis (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Endocrinology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Diabetes (AREA)
Reproductive Health (AREA)
Pain & Pain Management (AREA)
Psychiatry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Steroid Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Indole Compounds (AREA)
Hydrogenated Pyridines (AREA)

UA2003054188A 2000-11-20 2001-11-20 Use of gaboxadol as gaba enhancer for treatment of disorders relating to reduced neurosteroid activity UA77403C2 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DKPA200001743		2000-11-20
PCT/DK2001/000773 WO2002040009A1 (en)	2000-11-20	2001-11-20	Gaba enhancers in the treatment of diseases relating to reduced neurosteroid activity

Publications (1)

Publication Number	Publication Date
UA77403C2 true UA77403C2 (en)	2006-12-15

Family

ID=8159857

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
UA2003054188A UA77403C2 (en)	2000-11-20	2001-11-20	Use of gaboxadol as gaba enhancer for treatment of disorders relating to reduced neurosteroid activity

Country Status (33)

Country	Link
US (2)	US20040024038A1 (de)
EP (1)	EP1337247B1 (de)
JP (1)	JP4152186B2 (de)
KR (1)	KR100865651B1 (de)
CN (1)	CN1318027C (de)
AR (1)	AR031473A1 (de)
AT (1)	ATE336242T1 (de)
AU (2)	AU2351402A (de)
BG (1)	BG107909A (de)
BR (1)	BR0115668A (de)
CA (1)	CA2429220C (de)
CY (1)	CY1106209T1 (de)
CZ (1)	CZ20031383A3 (de)
DE (1)	DE60122368T2 (de)
DK (1)	DK1337247T3 (de)
EA (1)	EA007287B1 (de)
ES (1)	ES2266308T3 (de)
HR (1)	HRP20030404A2 (de)
HU (1)	HUP0400505A3 (de)
IL (1)	IL155587A0 (de)
IS (1)	IS2427B (de)
ME (1)	MEP6408A (de)
MX (1)	MXPA03004349A (de)
NO (1)	NO20032271D0 (de)
NZ (1)	NZ525520A (de)
PL (1)	PL361051A1 (de)
PT (1)	PT1337247E (de)
SI (1)	SI1337247T1 (de)
SK (1)	SK7682003A3 (de)
UA (1)	UA77403C2 (de)
WO (1)	WO2002040009A1 (de)
YU (1)	YU39003A (de)
ZA (1)	ZA200303289B (de)

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2001
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2003
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Also Published As

Publication number	Publication date
AR031473A1 (es)	2003-09-24
US20090143435A1 (en)	2009-06-04
SK7682003A3 (en)	2003-10-07
US20040024038A1 (en)	2004-02-05
CA2429220C (en)	2009-09-15
NZ525520A (en)	2005-04-29
DK1337247T3 (da)	2006-12-04
HRP20030404A2 (en)	2005-04-30
IL155587A0 (en)	2003-11-23
IS2427B (is)	2008-10-15
CN1318027C (zh)	2007-05-30
DE60122368D1 (de)	2006-09-28
CZ20031383A3 (cs)	2003-08-13
KR20030065517A (ko)	2003-08-06
HK1075010A1 (en)	2005-12-02
JP2004513921A (ja)	2004-05-13
KR100865651B1 (ko)	2008-10-29
MXPA03004349A (es)	2003-08-19
PL361051A1 (en)	2004-09-20
MEP6408A (xx)	2010-02-10
SI1337247T1 (sl)	2006-12-31
PT1337247E (pt)	2006-11-30
AU2351402A (en)	2002-05-27
BG107909A (bg)	2004-08-31
NO20032271L (no)	2003-05-20
EA200300594A1 (ru)	2003-10-30
BR0115668A (pt)	2003-09-02
EA007287B1 (ru)	2006-08-25
EP1337247B1 (de)	2006-08-16
ZA200303289B (en)	2005-07-27
IS6803A (is)	2003-04-30
ES2266308T3 (es)	2007-03-01
HUP0400505A2 (hu)	2004-07-28
EP1337247A1 (de)	2003-08-27
CA2429220A1 (en)	2002-05-23
CY1106209T1 (el)	2011-06-08
HUP0400505A3 (en)	2008-08-28
NO20032271D0 (no)	2003-05-20
YU39003A (sh)	2006-05-25
ATE336242T1 (de)	2006-09-15
AU2002223514B2 (en)	2006-11-30
WO2002040009A1 (en)	2002-05-23
JP4152186B2 (ja)	2008-09-17
DE60122368T2 (de)	2007-08-09
CN1592616A (zh)	2005-03-09

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BR112014027841B1 (pt)	2022-08-09	Uso de derivados de pirazola na fabricação de um fármaco para prevenir ou tratar constipação
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RU2812129C1 (ru)	2024-01-23	Гормональное средство для регуляции половой охоты у мелких домашних животных
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UA35073A (uk)	2001-03-15	Спосіб профілактики і лікування генітального ендометріозу