UA78194C2 - Method for revealing and identification of active components in extracts by chromatographic fingerprinting of "fingerprints" and processor of program data processing chromatograms - Google Patents
Method for revealing and identification of active components in extracts by chromatographic fingerprinting of "fingerprints" and processor of program data processing chromatograms Download PDFInfo
- Publication number
- UA78194C2 UA78194C2 UA2003032740A UA2003032740A UA78194C2 UA 78194 C2 UA78194 C2 UA 78194C2 UA 2003032740 A UA2003032740 A UA 2003032740A UA 2003032740 A UA2003032740 A UA 2003032740A UA 78194 C2 UA78194 C2 UA 78194C2
- Authority
- UA
- Ukraine
- Prior art keywords
- components
- fingerprints
- properties
- chemical
- polarity
- Prior art date
Links
- 238000000034 method Methods 0.000 title claims abstract description 236
- 239000000284 extract Substances 0.000 title claims description 32
- 238000012545 processing Methods 0.000 title claims description 6
- 239000003814 drug Substances 0.000 claims abstract description 209
- 239000000126 substance Substances 0.000 claims abstract description 182
- 230000001225 therapeutic effect Effects 0.000 claims abstract description 172
- 229940079593 drug Drugs 0.000 claims abstract description 141
- 238000002360 preparation method Methods 0.000 claims abstract description 130
- 238000007639 printing Methods 0.000 claims abstract description 6
- 229940126601 medicinal product Drugs 0.000 claims description 127
- 241000196324 Embryophyta Species 0.000 claims description 101
- 239000000203 mixture Substances 0.000 claims description 97
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims description 87
- 238000004458 analytical method Methods 0.000 claims description 78
- 239000000470 constituent Substances 0.000 claims description 64
- 239000003086 colorant Substances 0.000 claims description 59
- 238000010521 absorption reaction Methods 0.000 claims description 48
- 241000282414 Homo sapiens Species 0.000 claims description 41
- 201000010099 disease Diseases 0.000 claims description 37
- 230000000694 effects Effects 0.000 claims description 37
- 239000000523 sample Substances 0.000 claims description 32
- 150000001875 compounds Chemical class 0.000 claims description 31
- 238000010828 elution Methods 0.000 claims description 31
- 230000014759 maintenance of location Effects 0.000 claims description 30
- 230000021615 conjugation Effects 0.000 claims description 26
- 239000000463 material Substances 0.000 claims description 26
- 239000004615 ingredient Substances 0.000 claims description 24
- 238000000605 extraction Methods 0.000 claims description 20
- 238000001228 spectrum Methods 0.000 claims description 19
- 241001465754 Metazoa Species 0.000 claims description 18
- 235000013305 food Nutrition 0.000 claims description 18
- 230000008569 process Effects 0.000 claims description 18
- 235000019640 taste Nutrition 0.000 claims description 18
- 238000003908 quality control method Methods 0.000 claims description 17
- 238000004128 high performance liquid chromatography Methods 0.000 claims description 16
- WEVYAHXRMPXWCK-UHFFFAOYSA-N Acetonitrile Chemical compound CC#N WEVYAHXRMPXWCK-UHFFFAOYSA-N 0.000 claims description 13
- 239000004480 active ingredient Substances 0.000 claims description 13
- 125000002524 organometallic group Chemical group 0.000 claims description 13
- 230000007613 environmental effect Effects 0.000 claims description 12
- 230000001632 homeopathic effect Effects 0.000 claims description 12
- 239000002904 solvent Substances 0.000 claims description 12
- 230000003595 spectral effect Effects 0.000 claims description 10
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 9
- 239000003125 aqueous solvent Substances 0.000 claims description 9
- 230000008859 change Effects 0.000 claims description 9
- 238000010586 diagram Methods 0.000 claims description 9
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 9
- 238000010191 image analysis Methods 0.000 claims description 8
- 235000015489 Emblica officinalis Nutrition 0.000 claims description 7
- 240000009120 Phyllanthus emblica Species 0.000 claims description 7
- 238000000862 absorption spectrum Methods 0.000 claims description 7
- 235000019441 ethanol Nutrition 0.000 claims description 7
- 239000007788 liquid Substances 0.000 claims description 7
- 238000012360 testing method Methods 0.000 claims description 7
- 239000002131 composite material Substances 0.000 claims description 6
- 239000000872 buffer Substances 0.000 claims description 5
- 238000006243 chemical reaction Methods 0.000 claims description 5
- 238000002211 ultraviolet spectrum Methods 0.000 claims description 5
- 239000002207 metabolite Substances 0.000 claims description 4
- 239000008363 phosphate buffer Substances 0.000 claims description 4
- 239000012472 biological sample Substances 0.000 claims description 3
- 238000001514 detection method Methods 0.000 claims description 3
- 230000035945 sensitivity Effects 0.000 claims description 3
- 238000001429 visible spectrum Methods 0.000 claims description 3
- 238000011109 contamination Methods 0.000 claims description 2
- 239000003960 organic solvent Substances 0.000 claims description 2
- 150000003839 salts Chemical class 0.000 claims description 2
- 238000012546 transfer Methods 0.000 claims description 2
- 230000009466 transformation Effects 0.000 claims description 2
- NBIIXXVUZAFLBC-UHFFFAOYSA-N Phosphoric acid Chemical compound OP(O)(O)=O NBIIXXVUZAFLBC-UHFFFAOYSA-N 0.000 claims 2
- 230000002209 hydrophobic effect Effects 0.000 claims 2
- 229910000147 aluminium phosphate Inorganic materials 0.000 claims 1
- 238000013375 chromatographic separation Methods 0.000 claims 1
- ZPWVASYFFYYZEW-UHFFFAOYSA-L dipotassium hydrogen phosphate Chemical compound [K+].[K+].OP([O-])([O-])=O ZPWVASYFFYYZEW-UHFFFAOYSA-L 0.000 claims 1
- 230000003203 everyday effect Effects 0.000 claims 1
- 238000009472 formulation Methods 0.000 claims 1
- GNSKLFRGEWLPPA-UHFFFAOYSA-M potassium dihydrogen phosphate Chemical compound [K+].OP(O)([O-])=O GNSKLFRGEWLPPA-UHFFFAOYSA-M 0.000 claims 1
- 238000007726 management method Methods 0.000 abstract description 6
- 229940126672 traditional medicines Drugs 0.000 abstract description 2
- 208000035475 disorder Diseases 0.000 description 50
- 239000000047 product Substances 0.000 description 38
- 230000007246 mechanism Effects 0.000 description 17
- 238000004587 chromatography analysis Methods 0.000 description 15
- 235000013399 edible fruits Nutrition 0.000 description 15
- 240000004246 Agave americana Species 0.000 description 14
- 235000008754 Agave americana Nutrition 0.000 description 14
- 239000008280 blood Substances 0.000 description 14
- 210000004369 blood Anatomy 0.000 description 14
- 238000000926 separation method Methods 0.000 description 14
- 208000017520 skin disease Diseases 0.000 description 14
- 241000411851 herbal medicine Species 0.000 description 13
- 230000005855 radiation Effects 0.000 description 13
- 230000036541 health Effects 0.000 description 12
- 230000003993 interaction Effects 0.000 description 11
- 229940098465 tincture Drugs 0.000 description 10
- 238000011156 evaluation Methods 0.000 description 9
- 239000000843 powder Substances 0.000 description 9
- 230000009471 action Effects 0.000 description 8
- 206010012601 diabetes mellitus Diseases 0.000 description 8
- 230000009467 reduction Effects 0.000 description 8
- 230000005526 G1 to G0 transition Effects 0.000 description 7
- 230000008901 benefit Effects 0.000 description 7
- 230000005670 electromagnetic radiation Effects 0.000 description 7
- 230000009257 reactivity Effects 0.000 description 7
- 230000001105 regulatory effect Effects 0.000 description 7
- 235000003392 Curcuma domestica Nutrition 0.000 description 6
- 206010012735 Diarrhoea Diseases 0.000 description 6
- 235000003373 curcuma longa Nutrition 0.000 description 6
- 230000007721 medicinal effect Effects 0.000 description 6
- 238000004809 thin layer chromatography Methods 0.000 description 6
- 238000011282 treatment Methods 0.000 description 6
- 235000013976 turmeric Nutrition 0.000 description 6
- 102000004190 Enzymes Human genes 0.000 description 5
- 108090000790 Enzymes Proteins 0.000 description 5
- 230000015572 biosynthetic process Effects 0.000 description 5
- 230000001276 controlling effect Effects 0.000 description 5
- 210000002249 digestive system Anatomy 0.000 description 5
- 208000001848 dysentery Diseases 0.000 description 5
- 229930003935 flavonoid Natural products 0.000 description 5
- 150000002215 flavonoids Chemical class 0.000 description 5
- 235000017173 flavonoids Nutrition 0.000 description 5
- 230000006870 function Effects 0.000 description 5
- 229910052500 inorganic mineral Inorganic materials 0.000 description 5
- 238000005259 measurement Methods 0.000 description 5
- 239000011707 mineral Substances 0.000 description 5
- 238000001050 pharmacotherapy Methods 0.000 description 5
- 230000002441 reversible effect Effects 0.000 description 5
- 244000008991 Curcuma longa Species 0.000 description 4
- 206010052428 Wound Diseases 0.000 description 4
- 208000027418 Wounds and injury Diseases 0.000 description 4
- 238000002835 absorbance Methods 0.000 description 4
- 230000033228 biological regulation Effects 0.000 description 4
- 239000002537 cosmetic Substances 0.000 description 4
- 230000003247 decreasing effect Effects 0.000 description 4
- 230000029087 digestion Effects 0.000 description 4
- 230000001079 digestive effect Effects 0.000 description 4
- 239000003925 fat Substances 0.000 description 4
- 235000019197 fats Nutrition 0.000 description 4
- 235000011389 fruit/vegetable juice Nutrition 0.000 description 4
- 125000000524 functional group Chemical group 0.000 description 4
- 230000000670 limiting effect Effects 0.000 description 4
- 230000007774 longterm Effects 0.000 description 4
- 238000004519 manufacturing process Methods 0.000 description 4
- 230000003340 mental effect Effects 0.000 description 4
- 230000000269 nucleophilic effect Effects 0.000 description 4
- 239000003921 oil Substances 0.000 description 4
- 235000019198 oils Nutrition 0.000 description 4
- 210000000056 organ Anatomy 0.000 description 4
- 238000004451 qualitative analysis Methods 0.000 description 4
- 238000004445 quantitative analysis Methods 0.000 description 4
- 239000002689 soil Substances 0.000 description 4
- 238000002560 therapeutic procedure Methods 0.000 description 4
- 206010061218 Inflammation Diseases 0.000 description 3
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 3
- 238000013459 approach Methods 0.000 description 3
- 210000001124 body fluid Anatomy 0.000 description 3
- 239000010839 body fluid Substances 0.000 description 3
- 229910052796 boron Inorganic materials 0.000 description 3
- 239000003518 caustics Substances 0.000 description 3
- 230000001882 diuretic effect Effects 0.000 description 3
- 201000006549 dyspepsia Diseases 0.000 description 3
- 230000002068 genetic effect Effects 0.000 description 3
- 210000003128 head Anatomy 0.000 description 3
- 208000014617 hemorrhoid Diseases 0.000 description 3
- 229910052739 hydrogen Inorganic materials 0.000 description 3
- 230000006872 improvement Effects 0.000 description 3
- 230000004054 inflammatory process Effects 0.000 description 3
- 238000007689 inspection Methods 0.000 description 3
- 238000009434 installation Methods 0.000 description 3
- 229910052751 metal Inorganic materials 0.000 description 3
- 239000002184 metal Substances 0.000 description 3
- 235000013336 milk Nutrition 0.000 description 3
- 239000008267 milk Substances 0.000 description 3
- 210000004080 milk Anatomy 0.000 description 3
- 235000010755 mineral Nutrition 0.000 description 3
- 239000002547 new drug Substances 0.000 description 3
- 235000014571 nuts Nutrition 0.000 description 3
- 230000003285 pharmacodynamic effect Effects 0.000 description 3
- 230000000144 pharmacologic effect Effects 0.000 description 3
- 229930182490 saponin Natural products 0.000 description 3
- 235000017709 saponins Nutrition 0.000 description 3
- 150000007949 saponins Chemical class 0.000 description 3
- 238000002798 spectrophotometry method Methods 0.000 description 3
- 210000002784 stomach Anatomy 0.000 description 3
- 230000002485 urinary effect Effects 0.000 description 3
- 244000025254 Cannabis sativa Species 0.000 description 2
- 244000163122 Curcuma domestica Species 0.000 description 2
- 235000010469 Glycine max Nutrition 0.000 description 2
- BXNJHAXVSOCGBA-UHFFFAOYSA-N Harmine Chemical compound N1=CC=C2C3=CC=C(OC)C=C3NC2=C1C BXNJHAXVSOCGBA-UHFFFAOYSA-N 0.000 description 2
- 206010062717 Increased upper airway secretion Diseases 0.000 description 2
- 235000000177 Indigofera tinctoria Nutrition 0.000 description 2
- 241000102542 Kara Species 0.000 description 2
- 241000948268 Meda Species 0.000 description 2
- 206010028980 Neoplasm Diseases 0.000 description 2
- 235000015471 Pluchea indica Nutrition 0.000 description 2
- 206010037660 Pyrexia Diseases 0.000 description 2
- 240000004860 Salvia occidentalis Species 0.000 description 2
- 208000009911 Urinary Calculi Diseases 0.000 description 2
- 239000000370 acceptor Substances 0.000 description 2
- 230000002378 acidificating effect Effects 0.000 description 2
- 239000013543 active substance Substances 0.000 description 2
- 230000001154 acute effect Effects 0.000 description 2
- 229930013930 alkaloid Natural products 0.000 description 2
- 102000001307 androgen receptors Human genes 0.000 description 2
- 108010080146 androgen receptors Proteins 0.000 description 2
- 239000003048 aphrodisiac agent Substances 0.000 description 2
- 230000002509 aphrodisiac effect Effects 0.000 description 2
- 206010003246 arthritis Diseases 0.000 description 2
- 230000001174 ascending effect Effects 0.000 description 2
- 210000000941 bile Anatomy 0.000 description 2
- 230000004071 biological effect Effects 0.000 description 2
- 230000007321 biological mechanism Effects 0.000 description 2
- 238000004364 calculation method Methods 0.000 description 2
- 230000001684 chronic effect Effects 0.000 description 2
- 239000006071 cream Substances 0.000 description 2
- VFLDPWHFBUODDF-FCXRPNKRSA-N curcumin Chemical compound C1=C(O)C(OC)=CC(\C=C\C(=O)CC(=O)\C=C\C=2C=C(OC)C(O)=CC=2)=C1 VFLDPWHFBUODDF-FCXRPNKRSA-N 0.000 description 2
- 238000011161 development Methods 0.000 description 2
- 235000014113 dietary fatty acids Nutrition 0.000 description 2
- 239000003085 diluting agent Substances 0.000 description 2
- 239000002934 diuretic Substances 0.000 description 2
- POULHZVOKOAJMA-UHFFFAOYSA-N dodecanoic acid Chemical compound CCCCCCCCCCCC(O)=O POULHZVOKOAJMA-UHFFFAOYSA-N 0.000 description 2
- 230000002124 endocrine Effects 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 125000004494 ethyl ester group Chemical group 0.000 description 2
- MMXKVMNBHPAILY-UHFFFAOYSA-N ethyl laurate Chemical compound CCCCCCCCCCCC(=O)OCC MMXKVMNBHPAILY-UHFFFAOYSA-N 0.000 description 2
- 229930195729 fatty acid Natural products 0.000 description 2
- 239000000194 fatty acid Substances 0.000 description 2
- 150000004665 fatty acids Chemical class 0.000 description 2
- 239000012530 fluid Substances 0.000 description 2
- 230000036449 good health Effects 0.000 description 2
- 239000009437 guggulu extract Substances 0.000 description 2
- 230000035876 healing Effects 0.000 description 2
- 230000002443 hepatoprotective effect Effects 0.000 description 2
- 239000000321 herbal drug Substances 0.000 description 2
- 229930195733 hydrocarbon Natural products 0.000 description 2
- 150000002430 hydrocarbons Chemical class 0.000 description 2
- 229940097275 indigo Drugs 0.000 description 2
- COHYTHOBJLSHDF-UHFFFAOYSA-N indigo powder Natural products N1C2=CC=CC=C2C(=O)C1=C1C(=O)C2=CC=CC=C2N1 COHYTHOBJLSHDF-UHFFFAOYSA-N 0.000 description 2
- 230000000968 intestinal effect Effects 0.000 description 2
- 210000000936 intestine Anatomy 0.000 description 2
- 210000003734 kidney Anatomy 0.000 description 2
- 230000031700 light absorption Effects 0.000 description 2
- 210000004185 liver Anatomy 0.000 description 2
- 238000005461 lubrication Methods 0.000 description 2
- 150000002739 metals Chemical class 0.000 description 2
- 150000002894 organic compounds Chemical class 0.000 description 2
- 150000002902 organometallic compounds Chemical class 0.000 description 2
- 230000036961 partial effect Effects 0.000 description 2
- 239000011049 pearl Substances 0.000 description 2
- 208000026435 phlegm Diseases 0.000 description 2
- 230000000704 physical effect Effects 0.000 description 2
- 238000000746 purification Methods 0.000 description 2
- 238000011002 quantification Methods 0.000 description 2
- 238000011160 research Methods 0.000 description 2
- 208000023504 respiratory system disease Diseases 0.000 description 2
- 238000012552 review Methods 0.000 description 2
- 239000002453 shampoo Substances 0.000 description 2
- 238000007493 shaping process Methods 0.000 description 2
- 235000002639 sodium chloride Nutrition 0.000 description 2
- 241000894007 species Species 0.000 description 2
- 238000011425 standardization method Methods 0.000 description 2
- 239000004575 stone Substances 0.000 description 2
- 235000000346 sugar Nutrition 0.000 description 2
- 230000002195 synergetic effect Effects 0.000 description 2
- 208000008281 urolithiasis Diseases 0.000 description 2
- 230000000007 visual effect Effects 0.000 description 2
- INLFWQCRAJUDCR-IQVMEADQSA-N (1R,2S,4S,5'S,6R,7S,8R,9S,12S,13S)-5',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.02,9.04,8.013,18]icosane-6,2'-oxane] Chemical compound O([C@@H]1[C@@H]([C@]2(CC[C@@H]3[C@@]4(C)CCCCC4CC[C@H]3[C@@H]2C1)C)[C@@H]1C)[C@]11CC[C@H](C)CO1 INLFWQCRAJUDCR-IQVMEADQSA-N 0.000 description 1
- LPLLVINFLBSFRP-UHFFFAOYSA-N 2-methylamino-1-phenylpropan-1-one Chemical compound CNC(C)C(=O)C1=CC=CC=C1 LPLLVINFLBSFRP-UHFFFAOYSA-N 0.000 description 1
- PUKLDDOGISCFCP-JSQCKWNTSA-N 21-Deoxycortisone Chemical compound C1CC2=CC(=O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@@](C(=O)C)(O)[C@@]1(C)CC2=O PUKLDDOGISCFCP-JSQCKWNTSA-N 0.000 description 1
- 208000004998 Abdominal Pain Diseases 0.000 description 1
- 201000004384 Alopecia Diseases 0.000 description 1
- 241001388119 Anisotremus surinamensis Species 0.000 description 1
- 235000008725 Artocarpus heterophyllus Nutrition 0.000 description 1
- 244000025352 Artocarpus heterophyllus Species 0.000 description 1
- 201000004569 Blindness Diseases 0.000 description 1
- ZOXJGFHDIHLPTG-UHFFFAOYSA-N Boron Chemical compound [B] ZOXJGFHDIHLPTG-UHFFFAOYSA-N 0.000 description 1
- 235000004936 Bromus mango Nutrition 0.000 description 1
- 235000002566 Capsicum Nutrition 0.000 description 1
- 235000002568 Capsicum frutescens Nutrition 0.000 description 1
- 240000008574 Capsicum frutescens Species 0.000 description 1
- 239000004215 Carbon black (E152) Substances 0.000 description 1
- 235000014653 Carica parviflora Nutrition 0.000 description 1
- 244000132059 Carica parviflora Species 0.000 description 1
- DQFBYFPFKXHELB-UHFFFAOYSA-N Chalcone Natural products C=1C=CC=CC=1C(=O)C=CC1=CC=CC=C1 DQFBYFPFKXHELB-UHFFFAOYSA-N 0.000 description 1
- 206010008631 Cholera Diseases 0.000 description 1
- 235000008733 Citrus aurantifolia Nutrition 0.000 description 1
- 235000013162 Cocos nucifera Nutrition 0.000 description 1
- 244000060011 Cocos nucifera Species 0.000 description 1
- 208000002881 Colic Diseases 0.000 description 1
- 206010010774 Constipation Diseases 0.000 description 1
- 206010010904 Convulsion Diseases 0.000 description 1
- 240000003023 Cosmos bipinnatus Species 0.000 description 1
- 235000005956 Cosmos caudatus Nutrition 0.000 description 1
- 229920000742 Cotton Polymers 0.000 description 1
- 206010011224 Cough Diseases 0.000 description 1
- 241000283014 Dama Species 0.000 description 1
- 241001649081 Dina Species 0.000 description 1
- 208000004929 Facial Paralysis Diseases 0.000 description 1
- FCYKAQOGGFGCMD-UHFFFAOYSA-N Fulvic acid Natural products O1C2=CC(O)=C(O)C(C(O)=O)=C2C(=O)C2=C1CC(C)(O)OC2 FCYKAQOGGFGCMD-UHFFFAOYSA-N 0.000 description 1
- 241000967808 Garra Species 0.000 description 1
- 244000068988 Glycine max Species 0.000 description 1
- RERZNCLIYCABFS-UHFFFAOYSA-N Harmaline hydrochloride Natural products C1CN=C(C)C2=C1C1=CC=C(OC)C=C1N2 RERZNCLIYCABFS-UHFFFAOYSA-N 0.000 description 1
- 208000032843 Hemorrhage Diseases 0.000 description 1
- 206010019842 Hepatomegaly Diseases 0.000 description 1
- 241000282412 Homo Species 0.000 description 1
- 101000654674 Homo sapiens Semaphorin-6A Proteins 0.000 description 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 description 1
- 206010020751 Hypersensitivity Diseases 0.000 description 1
- 241000899793 Hypsophrys nicaraguensis Species 0.000 description 1
- 206010023126 Jaundice Diseases 0.000 description 1
- 240000007049 Juglans regia Species 0.000 description 1
- 235000009496 Juglans regia Nutrition 0.000 description 1
- 239000005639 Lauric acid Substances 0.000 description 1
- OYHQOLUKZRVURQ-HZJYTTRNSA-N Linoleic acid Chemical compound CCCCC\C=C/C\C=C/CCCCCCCC(O)=O OYHQOLUKZRVURQ-HZJYTTRNSA-N 0.000 description 1
- 208000019693 Lung disease Diseases 0.000 description 1
- 208000018501 Lymphatic disease Diseases 0.000 description 1
- 241000407429 Maja Species 0.000 description 1
- 235000014826 Mangifera indica Nutrition 0.000 description 1
- 240000007228 Mangifera indica Species 0.000 description 1
- 229910001300 Mazak (alloy) Inorganic materials 0.000 description 1
- 201000005505 Measles Diseases 0.000 description 1
- 208000019695 Migraine disease Diseases 0.000 description 1
- 241000751119 Mila <angiosperm> Species 0.000 description 1
- 244000302512 Momordica charantia Species 0.000 description 1
- 235000009811 Momordica charantia Nutrition 0.000 description 1
- 240000005561 Musa balbisiana Species 0.000 description 1
- 241000895811 Myza Species 0.000 description 1
- WJXSXWBOZMVFPJ-NENRSDFPSA-N N-[(2R,3R,4R,5S,6R)-4,5-dihydroxy-6-methoxy-2,4-dimethyloxan-3-yl]-N-methylacetamide Chemical compound CO[C@@H]1O[C@H](C)[C@@H](N(C)C(C)=O)[C@@](C)(O)[C@@H]1O WJXSXWBOZMVFPJ-NENRSDFPSA-N 0.000 description 1
- 235000006508 Nelumbo nucifera Nutrition 0.000 description 1
- 240000002853 Nelumbo nucifera Species 0.000 description 1
- 235000006510 Nelumbo pentapetala Nutrition 0.000 description 1
- 208000008589 Obesity Diseases 0.000 description 1
- 206010030113 Oedema Diseases 0.000 description 1
- 208000002193 Pain Diseases 0.000 description 1
- 241000022232 Pegopus Species 0.000 description 1
- 239000006002 Pepper Substances 0.000 description 1
- 201000005702 Pertussis Diseases 0.000 description 1
- 235000016761 Piper aduncum Nutrition 0.000 description 1
- 240000003889 Piper guineense Species 0.000 description 1
- 235000017804 Piper guineense Nutrition 0.000 description 1
- 235000008184 Piper nigrum Nutrition 0.000 description 1
- 208000025747 Rheumatic disease Diseases 0.000 description 1
- 206010039101 Rhinorrhoea Diseases 0.000 description 1
- 235000011449 Rosa Nutrition 0.000 description 1
- 241000122596 Salvia summa Species 0.000 description 1
- 235000006091 Salvia summa Nutrition 0.000 description 1
- 102100032795 Semaphorin-6A Human genes 0.000 description 1
- 208000013738 Sleep Initiation and Maintenance disease Diseases 0.000 description 1
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 1
- 206010041660 Splenomegaly Diseases 0.000 description 1
- 235000009184 Spondias indica Nutrition 0.000 description 1
- 241000519995 Stachys sylvatica Species 0.000 description 1
- 235000004298 Tamarindus indica Nutrition 0.000 description 1
- 240000004584 Tamarindus indica Species 0.000 description 1
- 241000724822 Teia Species 0.000 description 1
- 241000270666 Testudines Species 0.000 description 1
- 241000718541 Tetragastris balsamifera Species 0.000 description 1
- 244000269722 Thea sinensis Species 0.000 description 1
- 241001189642 Theroa Species 0.000 description 1
- 235000011941 Tilia x europaea Nutrition 0.000 description 1
- 235000008322 Trichosanthes cucumerina Nutrition 0.000 description 1
- 208000036826 VIIth nerve paralysis Diseases 0.000 description 1
- 235000014787 Vitis vinifera Nutrition 0.000 description 1
- 240000006365 Vitis vinifera Species 0.000 description 1
- 206010047700 Vomiting Diseases 0.000 description 1
- 238000001467 acupuncture Methods 0.000 description 1
- 239000000654 additive Substances 0.000 description 1
- 239000012675 alcoholic extract Substances 0.000 description 1
- 150000003797 alkaloid derivatives Chemical class 0.000 description 1
- 208000026935 allergic disease Diseases 0.000 description 1
- 230000007815 allergy Effects 0.000 description 1
- 150000001408 amides Chemical class 0.000 description 1
- 208000007502 anemia Diseases 0.000 description 1
- 230000000845 anti-microbial effect Effects 0.000 description 1
- 239000004599 antimicrobial Substances 0.000 description 1
- 208000006673 asthma Diseases 0.000 description 1
- 230000003416 augmentation Effects 0.000 description 1
- 229930015036 aurone Natural products 0.000 description 1
- 150000001530 aurones Chemical class 0.000 description 1
- 238000013475 authorization Methods 0.000 description 1
- 235000021015 bananas Nutrition 0.000 description 1
- YBHILYKTIRIUTE-UHFFFAOYSA-N berberine Chemical compound C1=C2CC[N+]3=CC4=C(OC)C(OC)=CC=C4C=C3C2=CC2=C1OCO2 YBHILYKTIRIUTE-UHFFFAOYSA-N 0.000 description 1
- 229940093265 berberine Drugs 0.000 description 1
- QISXPYZVZJBNDM-UHFFFAOYSA-N berberine Natural products COc1ccc2C=C3N(Cc2c1OC)C=Cc4cc5OCOc5cc34 QISXPYZVZJBNDM-UHFFFAOYSA-N 0.000 description 1
- 230000008238 biochemical pathway Effects 0.000 description 1
- 238000005842 biochemical reaction Methods 0.000 description 1
- 230000002715 bioenergetic effect Effects 0.000 description 1
- 208000034158 bleeding Diseases 0.000 description 1
- 230000000740 bleeding effect Effects 0.000 description 1
- 210000000988 bone and bone Anatomy 0.000 description 1
- 210000001185 bone marrow Anatomy 0.000 description 1
- 206010006451 bronchitis Diseases 0.000 description 1
- 235000015155 buttermilk Nutrition 0.000 description 1
- 239000003575 carbonaceous material Substances 0.000 description 1
- 230000000747 cardiac effect Effects 0.000 description 1
- 238000005266 casting Methods 0.000 description 1
- 235000019994 cava Nutrition 0.000 description 1
- 210000004027 cell Anatomy 0.000 description 1
- 210000000170 cell membrane Anatomy 0.000 description 1
- 230000001413 cellular effect Effects 0.000 description 1
- 150000001789 chalcones Chemical class 0.000 description 1
- 235000005513 chalcones Nutrition 0.000 description 1
- 230000002925 chemical effect Effects 0.000 description 1
- AQIXAKUUQRKLND-UHFFFAOYSA-N cimetidine Chemical compound N#C/N=C(/NC)NCCSCC=1N=CNC=1C AQIXAKUUQRKLND-UHFFFAOYSA-N 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 239000013065 commercial product Substances 0.000 description 1
- 230000000295 complement effect Effects 0.000 description 1
- 235000009508 confectionery Nutrition 0.000 description 1
- 238000012790 confirmation Methods 0.000 description 1
- 230000036461 convulsion Effects 0.000 description 1
- 235000012754 curcumin Nutrition 0.000 description 1
- 229940109262 curcumin Drugs 0.000 description 1
- 239000004148 curcumin Substances 0.000 description 1
- 230000006378 damage Effects 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 230000001419 dependent effect Effects 0.000 description 1
- 239000003599 detergent Substances 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- 235000005911 diet Nutrition 0.000 description 1
- 230000037213 diet Effects 0.000 description 1
- JNSGIVNNHKGGRU-JYRVWZFOSA-N diethoxyphosphinothioyl (2z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetate Chemical compound CCOP(=S)(OCC)OC(=O)C(=N/OC)\C1=CSC(N)=N1 JNSGIVNNHKGGRU-JYRVWZFOSA-N 0.000 description 1
- VFLDPWHFBUODDF-UHFFFAOYSA-N diferuloylmethane Natural products C1=C(O)C(OC)=CC(C=CC(=O)CC(=O)C=CC=2C=C(OC)C(O)=CC=2)=C1 VFLDPWHFBUODDF-UHFFFAOYSA-N 0.000 description 1
- 230000004069 differentiation Effects 0.000 description 1
- 238000010790 dilution Methods 0.000 description 1
- 239000012895 dilution Substances 0.000 description 1
- 230000006806 disease prevention Effects 0.000 description 1
- 239000002552 dosage form Substances 0.000 description 1
- 230000000857 drug effect Effects 0.000 description 1
- 230000009977 dual effect Effects 0.000 description 1
- 230000008030 elimination Effects 0.000 description 1
- 238000003379 elimination reaction Methods 0.000 description 1
- 239000003480 eluent Substances 0.000 description 1
- 239000003344 environmental pollutant Substances 0.000 description 1
- 230000002255 enzymatic effect Effects 0.000 description 1
- 206010015037 epilepsy Diseases 0.000 description 1
- 239000000469 ethanolic extract Substances 0.000 description 1
- FMMOOAYVCKXGMF-MURFETPASA-N ethyl linoleate Chemical compound CCCCC\C=C/C\C=C/CCCCCCCC(=O)OCC FMMOOAYVCKXGMF-MURFETPASA-N 0.000 description 1
- 239000010685 fatty oil Substances 0.000 description 1
- 239000000835 fiber Substances 0.000 description 1
- 229930003944 flavone Natural products 0.000 description 1
- 150000002213 flavones Chemical class 0.000 description 1
- 235000011949 flavones Nutrition 0.000 description 1
- 239000004088 foaming agent Substances 0.000 description 1
- 239000002509 fulvic acid Substances 0.000 description 1
- 229940095100 fulvic acid Drugs 0.000 description 1
- 210000000232 gallbladder Anatomy 0.000 description 1
- 239000007789 gas Substances 0.000 description 1
- 230000003676 hair loss Effects 0.000 description 1
- VJHLDRVYTQNASM-UHFFFAOYSA-N harmine Natural products CC1=CN=CC=2NC3=CC(=CC=C3C=21)OC VJHLDRVYTQNASM-UHFFFAOYSA-N 0.000 description 1
- 238000003306 harvesting Methods 0.000 description 1
- 208000024798 heartburn Diseases 0.000 description 1
- 229910001385 heavy metal Inorganic materials 0.000 description 1
- 235000012907 honey Nutrition 0.000 description 1
- 210000005260 human cell Anatomy 0.000 description 1
- 239000001257 hydrogen Substances 0.000 description 1
- 230000007062 hydrolysis Effects 0.000 description 1
- 238000006460 hydrolysis reaction Methods 0.000 description 1
- 230000008676 import Effects 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 230000002458 infectious effect Effects 0.000 description 1
- 206010022437 insomnia Diseases 0.000 description 1
- 230000003834 intracellular effect Effects 0.000 description 1
- 150000002500 ions Chemical class 0.000 description 1
- 238000002955 isolation Methods 0.000 description 1
- 229940112580 kovia Drugs 0.000 description 1
- 210000000867 larynx Anatomy 0.000 description 1
- 239000008141 laxative Substances 0.000 description 1
- 230000002475 laxative effect Effects 0.000 description 1
- 208000032839 leukemia Diseases 0.000 description 1
- 239000004571 lime Substances 0.000 description 1
- 235000020778 linoleic acid Nutrition 0.000 description 1
- OYHQOLUKZRVURQ-IXWMQOLASA-N linoleic acid Natural products CCCCC\C=C/C\C=C\CCCCCCCC(O)=O OYHQOLUKZRVURQ-IXWMQOLASA-N 0.000 description 1
- FMMOOAYVCKXGMF-UHFFFAOYSA-N linoleic acid ethyl ester Natural products CCCCCC=CCC=CCCCCCCCC(=O)OCC FMMOOAYVCKXGMF-UHFFFAOYSA-N 0.000 description 1
- 208000019423 liver disease Diseases 0.000 description 1
- 208000018555 lymphatic system disease Diseases 0.000 description 1
- 229940127554 medical product Drugs 0.000 description 1
- 108010041420 microbial alkaline proteinase inhibitor Proteins 0.000 description 1
- 206010027599 migraine Diseases 0.000 description 1
- 230000000116 mitigating effect Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 210000003097 mucus Anatomy 0.000 description 1
- 210000003205 muscle Anatomy 0.000 description 1
- 208000010753 nasal discharge Diseases 0.000 description 1
- 210000000653 nervous system Anatomy 0.000 description 1
- 230000000926 neurological effect Effects 0.000 description 1
- 230000002232 neuromuscular Effects 0.000 description 1
- 230000007935 neutral effect Effects 0.000 description 1
- 239000000041 non-steroidal anti-inflammatory agent Substances 0.000 description 1
- 229940021182 non-steroidal anti-inflammatory drug Drugs 0.000 description 1
- 235000016709 nutrition Nutrition 0.000 description 1
- 230000035764 nutrition Effects 0.000 description 1
- 235000020824 obesity Nutrition 0.000 description 1
- 230000003287 optical effect Effects 0.000 description 1
- 150000007524 organic acids Chemical class 0.000 description 1
- 235000005985 organic acids Nutrition 0.000 description 1
- 230000008447 perception Effects 0.000 description 1
- 239000000825 pharmaceutical preparation Substances 0.000 description 1
- 229940127557 pharmaceutical product Drugs 0.000 description 1
- 230000035479 physiological effects, processes and functions Effects 0.000 description 1
- 239000000902 placebo Substances 0.000 description 1
- 229940068196 placebo Drugs 0.000 description 1
- 238000003976 plant breeding Methods 0.000 description 1
- 239000000419 plant extract Substances 0.000 description 1
- 231100000719 pollutant Toxicity 0.000 description 1
- 238000001556 precipitation Methods 0.000 description 1
- 230000004224 protection Effects 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 238000001303 quality assessment method Methods 0.000 description 1
- 102000005962 receptors Human genes 0.000 description 1
- 108020003175 receptors Proteins 0.000 description 1
- 230000002829 reductive effect Effects 0.000 description 1
- 210000004994 reproductive system Anatomy 0.000 description 1
- 230000004044 response Effects 0.000 description 1
- 230000033764 rhythmic process Effects 0.000 description 1
- 239000003419 rna directed dna polymerase inhibitor Substances 0.000 description 1
- 210000004761 scalp Anatomy 0.000 description 1
- 238000012216 screening Methods 0.000 description 1
- 230000001932 seasonal effect Effects 0.000 description 1
- 210000000582 semen Anatomy 0.000 description 1
- 239000002893 slag Substances 0.000 description 1
- 239000000344 soap Substances 0.000 description 1
- 239000011780 sodium chloride Substances 0.000 description 1
- QPILZZVXGUNELN-UHFFFAOYSA-M sodium;4-amino-5-hydroxynaphthalene-2,7-disulfonate;hydron Chemical compound [Na+].OS(=O)(=O)C1=CC(O)=C2C(N)=CC(S([O-])(=O)=O)=CC2=C1 QPILZZVXGUNELN-UHFFFAOYSA-M 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 230000000392 somatic effect Effects 0.000 description 1
- OJLGASCOGOIOJR-UHFFFAOYSA-N soyasaponin gammag Natural products CC1=C(O)C(=O)CC(OC2CC(C)(C)CC3C4=CCC5C6(C)CCC(OC7OC(C(O)C(O)C7OC8OC(CO)C(O)C(O)C8O)C(=O)O)C(C)(CO)C6CCC5(C)C4(C)CCC23C)O1 OJLGASCOGOIOJR-UHFFFAOYSA-N 0.000 description 1
- 210000000952 spleen Anatomy 0.000 description 1
- 230000000707 stereoselective effect Effects 0.000 description 1
- 150000003431 steroids Chemical class 0.000 description 1
- 238000003860 storage Methods 0.000 description 1
- 230000001629 suppression Effects 0.000 description 1
- 239000002352 surface water Substances 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 208000011580 syndromic disease Diseases 0.000 description 1
- 208000006379 syphilis Diseases 0.000 description 1
- 230000009897 systematic effect Effects 0.000 description 1
- 230000035922 thirst Effects 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- 231100000048 toxicity data Toxicity 0.000 description 1
- 235000015112 vegetable and seed oil Nutrition 0.000 description 1
- 235000013343 vitamin Nutrition 0.000 description 1
- 239000011782 vitamin Substances 0.000 description 1
- 229940088594 vitamin Drugs 0.000 description 1
- 229930003231 vitamin Natural products 0.000 description 1
- 239000000341 volatile oil Substances 0.000 description 1
- 230000008673 vomiting Effects 0.000 description 1
- 235000020234 walnut Nutrition 0.000 description 1
- 230000003313 weakening effect Effects 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J19/008—Processes for carrying out reactions under cavitation conditions
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F02—COMBUSTION ENGINES; HOT-GAS OR COMBUSTION-PRODUCT ENGINE PLANTS
- F02M—SUPPLYING COMBUSTION ENGINES IN GENERAL WITH COMBUSTIBLE MIXTURES OR CONSTITUENTS THEREOF
- F02M27/00—Apparatus for treating combustion-air, fuel, or fuel-air mixture, by catalysts, electric means, magnetism, rays, sound waves, or the like
- F02M27/04—Apparatus for treating combustion-air, fuel, or fuel-air mixture, by catalysts, electric means, magnetism, rays, sound waves, or the like by electric means, ionisation, polarisation or magnetism
- F02M27/042—Apparatus for treating combustion-air, fuel, or fuel-air mixture, by catalysts, electric means, magnetism, rays, sound waves, or the like by electric means, ionisation, polarisation or magnetism by plasma
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F23—COMBUSTION APPARATUS; COMBUSTION PROCESSES
- F23C—METHODS OR APPARATUS FOR COMBUSTION USING FLUID FUEL OR SOLID FUEL SUSPENDED IN A CARRIER GAS OR AIR
- F23C99/00—Subject-matter not provided for in other groups of this subclass
- F23C99/003—Combustion process using sound or vibrations
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/88—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/08—Processes employing the direct application of electric or wave energy, or particle radiation; Apparatus therefor
- B01J2219/0894—Processes carried out in the presence of a plasma
- B01J2219/0898—Hot plasma
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/88—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86
- G01N2030/8809—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/88—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86
- G01N2030/8809—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample
- G01N2030/8813—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample biological materials
Landscapes
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Pathology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- General Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Analytical Chemistry (AREA)
- Mechanical Engineering (AREA)
- General Engineering & Computer Science (AREA)
- Combustion & Propulsion (AREA)
- Organic Chemistry (AREA)
- Plasma & Fusion (AREA)
- Medicines Containing Plant Substances (AREA)
- Medicinal Preparation (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medical Treatment And Welfare Office Work (AREA)
- Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
- Management, Administration, Business Operations System, And Electronic Commerce (AREA)
- Collating Specific Patterns (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/IN2000/000123 WO2002046739A1 (en) | 2000-12-08 | 2000-12-08 | A novel method for chromatographic finger printing and standardization of single medicines and formulations |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UA78194C2 true UA78194C2 (en) | 2007-03-15 |
Family
ID=11076288
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UA2003032740A UA78194C2 (en) | 2000-12-08 | 2000-08-12 | Method for revealing and identification of active components in extracts by chromatographic fingerprinting of "fingerprints" and processor of program data processing chromatograms |
Country Status (24)
| Country | Link |
|---|---|
| US (1) | US7144740B2 (da) |
| EP (1) | EP1340071B1 (da) |
| KR (1) | KR100809732B1 (da) |
| AP (1) | AP2102A (da) |
| AT (1) | ATE426802T1 (da) |
| AU (1) | AU2001237707A1 (da) |
| BR (1) | BR0017348B1 (da) |
| CA (1) | CA2424363C (da) |
| CY (1) | CY1109111T1 (da) |
| DE (1) | DE60041892D1 (da) |
| DK (1) | DK1340071T3 (da) |
| DZ (1) | DZ3508A1 (da) |
| EA (1) | EA004663B1 (da) |
| ES (1) | ES2324278T3 (da) |
| HR (1) | HRP20030241B1 (da) |
| IL (2) | IL155110A0 (da) |
| MX (1) | MXPA03002816A (da) |
| NO (1) | NO331997B1 (da) |
| NZ (1) | NZ525007A (da) |
| PL (1) | PL361810A1 (da) |
| PT (1) | PT1340071E (da) |
| RO (1) | RO122936B1 (da) |
| UA (1) | UA78194C2 (da) |
| WO (1) | WO2002046739A1 (da) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2002200085A (ja) * | 2000-10-27 | 2002-07-16 | Kazuo Ishii | 各臓器・経絡の異常の検知及びその健康維持用部材 |
| US20050053678A1 (en) * | 2001-10-03 | 2005-03-10 | Gow Robert T. | Methods and compositions for betel nut chewing gum |
| CN100339706C (zh) * | 2003-06-19 | 2007-09-26 | 北京中医药大学 | 一种由栀子和三七制备的注射液的质量控制方法 |
| CN1333248C (zh) * | 2003-07-14 | 2007-08-22 | 北京中医药大学 | 栀子药材和栀子半成品指纹图谱检测的质量控制方法 |
| US8032831B2 (en) * | 2003-09-30 | 2011-10-04 | Hyland Software, Inc. | Computer-implemented workflow replayer system and method |
| AU2005208148A1 (en) * | 2004-01-28 | 2005-08-11 | Council Of Scientific And Industrial Research | A method for standardization of chemical and therapeutic values of foods & medicines using animated chromatographic fingerprinting |
| CN100394177C (zh) * | 2004-06-02 | 2008-06-11 | 昆明贵金属研究所 | 阿司匹林铜高效液相色谱测定方法 |
| CN1965233B (zh) | 2004-06-07 | 2013-03-13 | 株式会社津村 | 多成分药剂的评价方法 |
| US20090081805A1 (en) * | 2007-09-24 | 2009-03-26 | The Hong Kong Polytechnic University | Method for finding active ingredients from chemical and biological systems |
| RU2393470C1 (ru) * | 2009-06-26 | 2010-06-27 | Открытое акционерное общество "ВНИПИгаздобыча" | Способ совместного определения ионов переходных металлов в природных и сточных водах методом высокоэффективной жидкостной хроматографии |
| US8461987B2 (en) * | 2010-11-17 | 2013-06-11 | Theodosios Kountotsis | System and method for performing chemical analysis of fingerprints for providing at least one response |
| KR101412655B1 (ko) * | 2011-06-01 | 2014-06-26 | 가부시키가이샤 쓰무라 | Fp작성방법, 작성프로그램, 작성장치, 및 fp |
| CN102879508B (zh) | 2011-07-15 | 2014-12-03 | 株式会社岛津制作所 | 用于液相色谱仪的控制设备 |
| US9946887B2 (en) * | 2012-06-04 | 2018-04-17 | Nokia Technologies Oy | Method and apparatus for determining privacy policy based on data and associated values |
| JP6127790B2 (ja) * | 2013-07-12 | 2017-05-17 | 株式会社島津製作所 | 液体クロマトグラフ用制御装置および制御方法 |
| FR3039278B1 (fr) * | 2015-07-23 | 2017-07-21 | Laboratoires M&L | Utilisation d'un compose comme marqueur d'un extrait vegetal |
| CN109374764B (zh) * | 2018-10-19 | 2021-05-14 | 广西中医药大学 | 八味龙钻颗粒hplc指纹图谱及主要成分含量测定方法 |
| WO2020239393A1 (en) * | 2019-05-24 | 2020-12-03 | Sartorius Stedim Biotech Gmbh | Chromatography method, method of determining the concentration of at least one compound in a chromatography method, method of obtaining an adsorption isotherm, method of obtaining at least one stationary phase and method of evaluating the accuracy of a predetermined adsorption isotherm |
| CN110426475B (zh) * | 2019-08-12 | 2022-04-01 | 宿州学院 | 一种保健凉茶的检测方法 |
| CN110514611B (zh) * | 2019-09-25 | 2023-01-20 | 深圳市药品检验研究院(深圳市医疗器械检测中心) | 一种基于药效信息建立评价中药质量的化学模式识别方法 |
| CN112101194B (zh) * | 2020-01-21 | 2024-09-13 | 神盾股份有限公司 | 电子装置及其操作方法 |
| CA3189540A1 (en) | 2020-07-16 | 2022-01-20 | Invacare Corporation | System and method for concentrating gas |
| AU2021307935A1 (en) | 2020-07-16 | 2023-03-16 | Ventec Life Systems, Inc. | System and method for concentrating gas |
| EP4181995A4 (en) | 2020-07-16 | 2025-05-07 | Ventec Life Systems, Inc. | System and method for concentrating gas |
| US11915570B2 (en) | 2020-07-16 | 2024-02-27 | Ventec Life Systems, Inc. | System and method for concentrating gas |
| CN113075370A (zh) * | 2021-03-12 | 2021-07-06 | 药都(本溪)一致科技有限公司 | 一种中药质量一致性测定方法、系统、介质及应用 |
| CN113311081B (zh) * | 2021-05-17 | 2023-08-11 | 清华大学 | 基于三维液相色谱指纹的污染源识别方法及装置 |
| US12347555B2 (en) | 2021-07-15 | 2025-07-01 | Ventec Life Systems, Inc. | System and method for medical device communication |
| CN115825316B (zh) * | 2023-02-15 | 2023-06-16 | 武汉宏韧生物医药股份有限公司 | 基于超临界色谱法的药物有效成分分析方法及装置 |
| CN119125351B (zh) * | 2024-09-06 | 2025-04-04 | 湖南易能生物医药有限公司 | 一种包含枳壳和薄荷的中药复方的质量控制方法及其应用 |
| CN120404616B (zh) * | 2025-07-01 | 2025-09-12 | 北京春风药业有限公司 | 一种中药品质检测方法及系统 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH02253156A (ja) * | 1989-03-27 | 1990-10-11 | Shimadzu Corp | 分取クロマトグラフィ及びその装置 |
| GB2230967B (en) * | 1989-04-20 | 1993-12-08 | Philips Electronic Associated | Liquid chromatography |
| DE69013137T2 (de) * | 1990-01-18 | 1995-03-02 | Hewlett Packard Co | Verfahren zur Unterscheidung von Mischungen chemischer Verbindungen. |
| EP0486030B1 (en) * | 1990-11-16 | 1997-01-15 | Shimadzu Corporation | Fraction purity measuring apparatus for chromatogram peak |
| US5254474A (en) | 1991-02-25 | 1993-10-19 | The United States Of America As Represented By The Secretary Of The Army | Method of assessing thermal processing of food using intrinsically-created compounds |
| JPH04355366A (ja) * | 1991-05-31 | 1992-12-09 | Shimadzu Corp | 成分純度検定方法 |
| US6466923B1 (en) * | 1997-05-12 | 2002-10-15 | Chroma Graphics, Inc. | Method and apparatus for biomathematical pattern recognition |
| JPH1172489A (ja) * | 1997-08-28 | 1999-03-16 | Hitachi Ltd | 液体クロマトグラフ |
| EP1044370B1 (en) * | 1997-12-30 | 2017-08-23 | Caliper Life Sciences, Inc. | Software for the display of chromatographic separation data |
-
2000
- 2000-08-12 UA UA2003032740A patent/UA78194C2/uk unknown
- 2000-12-08 IL IL15511000A patent/IL155110A0/xx unknown
- 2000-12-08 KR KR1020037004624A patent/KR100809732B1/ko not_active Expired - Fee Related
- 2000-12-08 WO PCT/IN2000/000123 patent/WO2002046739A1/en not_active Ceased
- 2000-12-08 PT PT00991991T patent/PT1340071E/pt unknown
- 2000-12-08 NZ NZ525007A patent/NZ525007A/en not_active IP Right Cessation
- 2000-12-08 CA CA2424363A patent/CA2424363C/en not_active Expired - Lifetime
- 2000-12-08 DK DK00991991T patent/DK1340071T3/da active
- 2000-12-08 EA EA200300320A patent/EA004663B1/ru not_active IP Right Cessation
- 2000-12-08 EP EP00991991A patent/EP1340071B1/en not_active Expired - Lifetime
- 2000-12-08 RO ROA200300269A patent/RO122936B1/ro unknown
- 2000-12-08 MX MXPA03002816A patent/MXPA03002816A/es active IP Right Grant
- 2000-12-08 AU AU2001237707A patent/AU2001237707A1/en not_active Abandoned
- 2000-12-08 DE DE60041892T patent/DE60041892D1/de not_active Expired - Lifetime
- 2000-12-08 BR BRPI0017348-7A patent/BR0017348B1/pt active IP Right Grant
- 2000-12-08 DZ DZ003508A patent/DZ3508A1/fr active
- 2000-12-08 PL PL36181000A patent/PL361810A1/xx not_active IP Right Cessation
- 2000-12-08 AT AT00991991T patent/ATE426802T1/de active
- 2000-12-08 HR HRP20030241AA patent/HRP20030241B1/hr not_active IP Right Cessation
- 2000-12-08 ES ES00991991T patent/ES2324278T3/es not_active Expired - Lifetime
-
2001
- 2001-02-08 US US09/779,377 patent/US7144740B2/en not_active Expired - Lifetime
- 2001-09-20 AP APAP/P/2003/002770A patent/AP2102A/en active
-
2003
- 2003-03-26 NO NO20031376A patent/NO331997B1/no not_active IP Right Cessation
- 2003-03-27 IL IL155110A patent/IL155110A/en active IP Right Grant
-
2009
- 2009-05-29 CY CY20091100575T patent/CY1109111T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| RO122936B1 (ro) | 2010-04-30 |
| DE60041892D1 (de) | 2009-05-07 |
| BR0017348A (pt) | 2004-08-03 |
| EA200300320A1 (ru) | 2003-10-30 |
| NO331997B1 (no) | 2012-05-21 |
| PL361810A1 (en) | 2004-10-04 |
| BR0017348B1 (pt) | 2013-04-16 |
| PT1340071E (pt) | 2009-06-30 |
| EA004663B1 (ru) | 2004-06-24 |
| AP2003002770A0 (en) | 2003-03-31 |
| KR100809732B1 (ko) | 2008-03-06 |
| DK1340071T3 (da) | 2009-06-22 |
| EP1340071B1 (en) | 2009-03-25 |
| CA2424363A1 (en) | 2002-06-13 |
| AU2001237707A1 (en) | 2002-06-18 |
| IL155110A0 (en) | 2003-10-31 |
| CA2424363C (en) | 2014-06-10 |
| HRP20030241B1 (hr) | 2013-05-31 |
| WO2002046739A1 (en) | 2002-06-13 |
| CY1109111T1 (el) | 2014-07-02 |
| US7144740B2 (en) | 2006-12-05 |
| KR20030061373A (ko) | 2003-07-18 |
| HRP20030241A2 (en) | 2005-04-30 |
| ES2324278T3 (es) | 2009-08-04 |
| MXPA03002816A (es) | 2003-10-14 |
| IL155110A (en) | 2010-06-30 |
| EP1340071A1 (en) | 2003-09-03 |
| NO20031376D0 (no) | 2003-03-26 |
| ATE426802T1 (de) | 2009-04-15 |
| NZ525007A (en) | 2005-02-25 |
| US20030068828A1 (en) | 2003-04-10 |
| DZ3508A1 (fr) | 2002-06-13 |
| AP2102A (en) | 2010-02-08 |
| NO20031376L (no) | 2003-08-08 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| UA78194C2 (en) | Method for revealing and identification of active components in extracts by chromatographic fingerprinting of "fingerprints" and processor of program data processing chromatograms | |
| JP5743940B2 (ja) | アニメーション化クロマトグラフィック・フィンガープリンティングを使った食品・医薬品の化学的および治療的価値の標定方法 | |
| US7662638B2 (en) | Method for chromatographic finger printing and standardization of single medicines and formulations | |
| Liu et al. | Authentication of herbal medicines based on modern analytical technology combined with chemometrics approach: A review | |
| Joshi | Herbal drugs and fingerprints: evidence based herbal drugs | |
| JP2002214215A (ja) | クロマトグラフフィンガープリントならびに単一の医薬および処方物の標準化のための新規な方法 | |
| CN100356380C (zh) | 一种色谱指纹图谱和单一药物和制剂标准化的新方法 | |
| Mangathayaru | Pharmacognosy: an Indian perspective | |
| Fawzi et al. | Determination of heavy metals and other toxic ingredients in henna (Lawsonia inermis) | |
| AU2011203008A1 (en) | A method of standardization of chemical and therapeutic values of foods and medicines using animated chromatographic fingerprinting | |
| AU783898B2 (en) | A novel method for chromatographic finger printing and standardization of single medicines and formulations | |
| AU2015201712A1 (en) | A method of standardization of chemical and therapeutic values of foods & medicines using animated chromatographic fingerprinting | |
| Mulaudzi et al. | HPTLC Profiling, Quality Control and FTIR Coupled with Chemometrics Analysis for Securidaca longipenduculata Fresen | |
| HK1048865B (en) | A novel method for chromatographic finger printing and standardization of single medicines and formulations | |
| Khatoon | Evaluation of Ayurvedic compound formulations III-Laghugangadhar Churna | |
| JP2011090007A (ja) | クロマトグラフフィンガープリントならびに単一の医薬および処方物の標準化のための新規な方法 | |
| Barbosa et al. | Registration of phytomedicines: technical requirements and highlights on regulation instruments | |
| Adnyane et al. | Intellectual Property Rights Related | |
| Verma et al. | Role of Spectroscopy in Traditional System of Medicine | |
| ZA200302435B (en) | A novel method for chromatographic finger printing and standardization of single medicines and formulations. | |
| Adnyane et al. | Irmanida Batubara, Shadila Fira Asoka | |
| Treasure | Food, Medicine, Poison & Molecular Multitasking | |
| Sherin et al. | A UNIQUE POLYHERBAL FORMULATION FOR COGNITIVE ENHANCEMENT AND MENTAL HEALTH SUPPORT | |
| Chan | Applications of chemometrics techniques on chromatographic and spectroscopic methods to advance chemical analysis of Radix Ligustici Chuanxiong, Radix Angelicae Sinensis, Cortex Phellodendri and other Chinese herbal medicines |