UA78242C2 - Lysine-containing chewing tablet - Google Patents

Lysine-containing chewing tablet Download PDF

Info

Publication number: UA78242C2
Authority: UA; Ukraine
Prior art keywords: vitamin; lysine; children; tablet; tablets
Prior art date: 2001-10-23

Application number

UA20040503844A

Other languages

English (en)

Ukrainian (uk)

Inventor

Michael David Marocchi

Original Assignee

Boehringer Ingelheim Int

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-10-23

Filing date

2002-10-23

Publication date

2007-03-15

2002-10-23 Application filed by Boehringer Ingelheim Int filed Critical Boehringer Ingelheim Int

2007-03-15 Publication of UA78242C2 publication Critical patent/UA78242C2/uk

Links

239000004472 Lysine Substances 0.000 title abstract description 24
KDXKERNSBIXSRK-UHFFFAOYSA-N Lysine Natural products NCCCCC(N)C(O)=O KDXKERNSBIXSRK-UHFFFAOYSA-N 0.000 title abstract description 20
230000001055 chewing effect Effects 0.000 title abstract description 4
229940088594 vitamin Drugs 0.000 abstract description 20
229930003231 vitamin Natural products 0.000 abstract description 20
235000013343 vitamin Nutrition 0.000 abstract description 20
239000011782 vitamin Substances 0.000 abstract description 20
150000003722 vitamin derivatives Chemical class 0.000 abstract description 16
229910052500 inorganic mineral Inorganic materials 0.000 abstract description 9
239000011707 mineral Substances 0.000 abstract description 9
235000003599 food sweetener Nutrition 0.000 abstract description 6
150000003839 salts Chemical class 0.000 abstract description 6
239000003765 sweetening agent Substances 0.000 abstract description 6
239000000796 flavoring agent Substances 0.000 abstract description 3
235000013355 food flavoring agent Nutrition 0.000 abstract description 3
235000019634 flavors Nutrition 0.000 abstract 1
230000000873 masking effect Effects 0.000 abstract 1
229960003646 lysine Drugs 0.000 description 21
239000003826 tablet Substances 0.000 description 21
KDXKERNSBIXSRK-YFKPBYRVSA-N L-lysine Chemical compound NCCCC[C@H](N)C(O)=O KDXKERNSBIXSRK-YFKPBYRVSA-N 0.000 description 18
235000018977 lysine Nutrition 0.000 description 17
XLOMVQKBTHCTTD-UHFFFAOYSA-N Zinc monoxide Chemical compound [Zn]=O XLOMVQKBTHCTTD-UHFFFAOYSA-N 0.000 description 10
239000000203 mixture Substances 0.000 description 10
OVBPIULPVIDEAO-LBPRGKRZSA-N folic acid Chemical compound C=1N=C2NC(N)=NC(=O)C2=NC=1CNC1=CC=C(C(=O)N[C@@H](CCC(O)=O)C(O)=O)C=C1 OVBPIULPVIDEAO-LBPRGKRZSA-N 0.000 description 8
235000010755 mineral Nutrition 0.000 description 8
-1 for example Natural products 0.000 description 7
CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 description 6
239000000395 magnesium oxide Substances 0.000 description 5
CPLXHLVBOLITMK-UHFFFAOYSA-N magnesium oxide Inorganic materials [Mg]=O CPLXHLVBOLITMK-UHFFFAOYSA-N 0.000 description 5
AXZKOIWUVFPNLO-UHFFFAOYSA-N magnesium;oxygen(2-) Chemical compound [O-2].[Mg+2] AXZKOIWUVFPNLO-UHFFFAOYSA-N 0.000 description 5
238000000034 method Methods 0.000 description 5
239000011787 zinc oxide Substances 0.000 description 5
YBJHBAHKTGYVGT-ZKWXMUAHSA-N (+)-Biotin Chemical compound N1C(=O)N[C@@H]2[C@H](CCCCC(=O)O)SC[C@@H]21 YBJHBAHKTGYVGT-ZKWXMUAHSA-N 0.000 description 4
FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 description 4
235000019739 Dicalciumphosphate Nutrition 0.000 description 4
WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 4
OVBPIULPVIDEAO-UHFFFAOYSA-N N-Pteroyl-L-glutaminsaeure Natural products C=1N=C2NC(N)=NC(=O)C2=NC=1CNC1=CC=C(C(=O)NC(CCC(O)=O)C(O)=O)C=C1 OVBPIULPVIDEAO-UHFFFAOYSA-N 0.000 description 4
DFPAKSUCGFBDDF-UHFFFAOYSA-N Nicotinamide Chemical compound NC(=O)C1=CC=CN=C1 DFPAKSUCGFBDDF-UHFFFAOYSA-N 0.000 description 4
229930003756 Vitamin B7 Natural products 0.000 description 4
239000001506 calcium phosphate Substances 0.000 description 4
239000000969 carrier Substances 0.000 description 4
239000003795 chemical substances by application Substances 0.000 description 4
229940116318 copper carbonate Drugs 0.000 description 4
GEZOTWYUIKXWOA-UHFFFAOYSA-L copper;carbonate Chemical compound [Cu+2].[O-]C([O-])=O GEZOTWYUIKXWOA-UHFFFAOYSA-L 0.000 description 4
229940038472 dicalcium phosphate Drugs 0.000 description 4
229910000390 dicalcium phosphate Inorganic materials 0.000 description 4
235000005911 diet Nutrition 0.000 description 4
230000000378 dietary effect Effects 0.000 description 4
229960000304 folic acid Drugs 0.000 description 4
235000019152 folic acid Nutrition 0.000 description 4
239000011724 folic acid Substances 0.000 description 4
239000008103 glucose Substances 0.000 description 4
WTEVQBCEXWBHNA-YFHOEESVSA-N neral Chemical compound CC(C)=CCC\C(C)=C/C=O WTEVQBCEXWBHNA-YFHOEESVSA-N 0.000 description 4
239000000843 powder Substances 0.000 description 4
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235000019160 vitamin B3 Nutrition 0.000 description 4
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IMWCPTKSESEZCL-SPSNFJOYSA-H (e)-but-2-enedioate;iron(3+) Chemical compound [Fe+3].[Fe+3].[O-]C(=O)\C=C\C([O-])=O.[O-]C(=O)\C=C\C([O-])=O.[O-]C(=O)\C=C\C([O-])=O IMWCPTKSESEZCL-SPSNFJOYSA-H 0.000 description 3
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ZAKOWWREFLAJOT-CEFNRUSXSA-N D-alpha-tocopherylacetate Chemical compound CC(=O)OC1=C(C)C(C)=C2O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1C ZAKOWWREFLAJOT-CEFNRUSXSA-N 0.000 description 3
ZZZCUOFIHGPKAK-UHFFFAOYSA-N D-erythro-ascorbic acid Natural products OCC1OC(=O)C(O)=C1O ZZZCUOFIHGPKAK-UHFFFAOYSA-N 0.000 description 3
VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 3
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FPIPGXGPPPQFEQ-OVSJKPMPSA-N all-trans-retinol Chemical compound OC\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-OVSJKPMPSA-N 0.000 description 3
239000011575 calcium Substances 0.000 description 3
229910052791 calcium Inorganic materials 0.000 description 3
235000015111 chews Nutrition 0.000 description 3
KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 description 3
AGVAZMGAQJOSFJ-WZHZPDAFSA-M cobalt(2+);[(2r,3s,4r,5s)-5-(5,6-dimethylbenzimidazol-1-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl] [(2r)-1-[3-[(1r,2r,3r,4z,7s,9z,12s,13s,14z,17s,18s,19r)-2,13,18-tris(2-amino-2-oxoethyl)-7,12,17-tris(3-amino-3-oxopropyl)-3,5,8,8,13,15,18,19-octamethyl-2 Chemical compound [Co+2].N#[C-].[N-]([C@@H]1[C@H](CC(N)=O)[C@@]2(C)CCC(=O)NC[C@@H](C)OP(O)(=O)O[C@H]3[C@H]([C@H](O[C@@H]3CO)N3C4=CC(C)=C(C)C=C4N=C3)O)\C2=C(C)/C([C@H](C\2(C)C)CCC(N)=O)=N/C/2=C\C([C@H]([C@@]/2(CC(N)=O)C)CCC(N)=O)=N\C\2=C(C)/C2=N[C@]1(C)[C@@](C)(CC(N)=O)[C@@H]2CCC(N)=O AGVAZMGAQJOSFJ-WZHZPDAFSA-M 0.000 description 3
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NEFBYIFKOOEVPA-UHFFFAOYSA-K dicalcium phosphate Chemical compound [Ca+2].[Ca+2].[O-]P([O-])([O-])=O NEFBYIFKOOEVPA-UHFFFAOYSA-K 0.000 description 3
239000003085 diluting agent Substances 0.000 description 3
239000000975 dye Substances 0.000 description 3
235000013305 food Nutrition 0.000 description 3
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235000019163 vitamin B12 Nutrition 0.000 description 3
239000011715 vitamin B12 Substances 0.000 description 3
235000019154 vitamin C Nutrition 0.000 description 3
239000011718 vitamin C Substances 0.000 description 3
GVJHHUAWPYXKBD-UHFFFAOYSA-N (±)-α-Tocopherol Chemical compound OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 description 2
FPIPGXGPPPQFEQ-UHFFFAOYSA-N 13-cis retinol Natural products OCC=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-UHFFFAOYSA-N 0.000 description 2
WTEVQBCEXWBHNA-UHFFFAOYSA-N Citral Natural products CC(C)=CCCC(C)=CC=O WTEVQBCEXWBHNA-UHFFFAOYSA-N 0.000 description 2
AUNGANRZJHBGPY-UHFFFAOYSA-N D-Lyxoflavin Natural products OCC(O)C(O)C(O)CN1C=2C=C(C)C(C)=CC=2N=C2C1=NC(=O)NC2=O AUNGANRZJHBGPY-UHFFFAOYSA-N 0.000 description 2
FBPFZTCFMRRESA-KVTDHHQDSA-N D-Mannitol Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KVTDHHQDSA-N 0.000 description 2
DHMQDGOQFOQNFH-UHFFFAOYSA-N Glycine Chemical compound NCC(O)=O DHMQDGOQFOQNFH-UHFFFAOYSA-N 0.000 description 2
229930195725 Mannitol Natural products 0.000 description 2
AUNGANRZJHBGPY-SCRDCRAPSA-N Riboflavin Chemical compound OC[C@@H](O)[C@@H](O)[C@@H](O)CN1C=2C=C(C)C(C)=CC=2N=C2C1=NC(=O)NC2=O AUNGANRZJHBGPY-SCRDCRAPSA-N 0.000 description 2
VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 2
XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 description 2
229930003471 Vitamin B2 Natural products 0.000 description 2
239000013543 active substance Substances 0.000 description 2
OSGAYBCDTDRGGQ-UHFFFAOYSA-L calcium sulfate Chemical compound [Ca+2].[O-]S([O-])(=O)=O OSGAYBCDTDRGGQ-UHFFFAOYSA-L 0.000 description 2
235000012730 carminic acid Nutrition 0.000 description 2
WTEVQBCEXWBHNA-JXMROGBWSA-N citral A Natural products CC(C)=CCC\C(C)=C\C=O WTEVQBCEXWBHNA-JXMROGBWSA-N 0.000 description 2
239000000945 filler Substances 0.000 description 2
239000007937 lozenge Substances 0.000 description 2
239000000314 lubricant Substances 0.000 description 2
HQKMJHAJHXVSDF-UHFFFAOYSA-L magnesium stearate Chemical compound [Mg+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O HQKMJHAJHXVSDF-UHFFFAOYSA-L 0.000 description 2
239000000594 mannitol Substances 0.000 description 2
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238000004519 manufacturing process Methods 0.000 description 2
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239000013589 supplement Substances 0.000 description 2
239000006188 syrup Substances 0.000 description 2
235000020357 syrup Nutrition 0.000 description 2
235000019164 vitamin B2 Nutrition 0.000 description 2
239000011716 vitamin B2 Substances 0.000 description 2
SMZOUWXMTYCWNB-UHFFFAOYSA-N 2-(2-methoxy-5-methylphenyl)ethanamine Chemical compound COC1=CC=C(C)C=C1CCN SMZOUWXMTYCWNB-UHFFFAOYSA-N 0.000 description 1
NIXOWILDQLNWCW-UHFFFAOYSA-N 2-Propenoic acid Natural products OC(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 description 1
244000215068 Acacia senegal Species 0.000 description 1
QGZKDVFQNNGYKY-UHFFFAOYSA-O Ammonium Chemical compound [NH4+] QGZKDVFQNNGYKY-UHFFFAOYSA-O 0.000 description 1
241000416162 Astragalus gummifer Species 0.000 description 1
240000004542 Capparis mitchellii Species 0.000 description 1
102000011632 Caseins Human genes 0.000 description 1
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241000207199 Citrus Species 0.000 description 1
239000005749 Copper compound Substances 0.000 description 1
FBPFZTCFMRRESA-JGWLITMVSA-N D-glucitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-JGWLITMVSA-N 0.000 description 1
240000003133 Elaeis guineensis Species 0.000 description 1
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SQUHHTBVTRBESD-UHFFFAOYSA-N Hexa-Ac-myo-Inositol Natural products CC(=O)OC1C(OC(C)=O)C(OC(C)=O)C(OC(C)=O)C(OC(C)=O)C1OC(C)=O SQUHHTBVTRBESD-UHFFFAOYSA-N 0.000 description 1
DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 1
GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 description 1
WHXSMMKQMYFTQS-UHFFFAOYSA-N Lithium Chemical compound [Li] WHXSMMKQMYFTQS-UHFFFAOYSA-N 0.000 description 1
FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 description 1
229910002651 NO3 Inorganic materials 0.000 description 1
NHNBFGGVMKEFGY-UHFFFAOYSA-N Nitrate Chemical compound [O-][N+]([O-])=O NHNBFGGVMKEFGY-UHFFFAOYSA-N 0.000 description 1
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FPIPGXGPPPQFEQ-BOOMUCAASA-N Vitamin A Natural products OC/C=C(/C)\C=C\C=C(\C)/C=C/C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-BOOMUCAASA-N 0.000 description 1
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210000004080 milk Anatomy 0.000 description 1
210000001331 nose Anatomy 0.000 description 1
TWNQGVIAIRXVLR-UHFFFAOYSA-N oxo(oxoalumanyloxy)alumane Chemical compound O=[Al]O[Al]=O TWNQGVIAIRXVLR-UHFFFAOYSA-N 0.000 description 1
230000035790 physiological processes and functions Effects 0.000 description 1
239000006187 pill Substances 0.000 description 1
239000001267 polyvinylpyrrolidone Substances 0.000 description 1
235000013855 polyvinylpyrrolidone Nutrition 0.000 description 1
229920000036 polyvinylpyrrolidone Polymers 0.000 description 1
239000003755 preservative agent Substances 0.000 description 1
230000002265 prevention Effects 0.000 description 1
229960003471 retinol Drugs 0.000 description 1
235000020944 retinol Nutrition 0.000 description 1
239000011607 retinol Substances 0.000 description 1
239000000901 saccharin and its Na,K and Ca salt Substances 0.000 description 1
210000003296 saliva Anatomy 0.000 description 1
229920006395 saturated elastomer Polymers 0.000 description 1
CDAISMWEOUEBRE-UHFFFAOYSA-N scyllo-inosotol Natural products OC1C(O)C(O)C(O)C(O)C1O CDAISMWEOUEBRE-UHFFFAOYSA-N 0.000 description 1
239000000377 silicon dioxide Substances 0.000 description 1
235000012239 silicon dioxide Nutrition 0.000 description 1
239000011734 sodium Substances 0.000 description 1
229910052708 sodium Inorganic materials 0.000 description 1
229940080237 sodium caseinate Drugs 0.000 description 1
239000008107 starch Substances 0.000 description 1
235000019698 starch Nutrition 0.000 description 1
239000004173 sunset yellow FCF Substances 0.000 description 1
DPJRMOMPQZCRJU-UHFFFAOYSA-M thiamine hydrochloride Chemical compound Cl.[Cl-].CC1=C(CCO)SC=[N+]1CC1=CN=C(C)N=C1N DPJRMOMPQZCRJU-UHFFFAOYSA-M 0.000 description 1
UIERGBJEBXXIGO-UHFFFAOYSA-N thiamine mononitrate Chemical compound [O-][N+]([O-])=O.CC1=C(CCO)SC=[N+]1CC1=CN=C(C)N=C1N UIERGBJEBXXIGO-UHFFFAOYSA-N 0.000 description 1
230000001988 toxicity Effects 0.000 description 1
231100000419 toxicity Toxicity 0.000 description 1
235000019155 vitamin A Nutrition 0.000 description 1
239000011719 vitamin A Substances 0.000 description 1
235000019156 vitamin B Nutrition 0.000 description 1
239000011720 vitamin B Substances 0.000 description 1
235000019165 vitamin E Nutrition 0.000 description 1
229940046009 vitamin E Drugs 0.000 description 1
239000011709 vitamin E Substances 0.000 description 1
229940045997 vitamin a Drugs 0.000 description 1
150000003752 zinc compounds Chemical class 0.000 description 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
- A61K33/10—Carbonates; Bicarbonates
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
- A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5015—Organic compounds, e.g. fats, sugars

Landscapes

Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Medicinal Chemistry (AREA)
Physical Education & Sports Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
General Chemical & Material Sciences (AREA)
Rheumatology (AREA)
Obesity (AREA)
Nutrition Science (AREA)
Hematology (AREA)
Diabetes (AREA)
Epidemiology (AREA)
Orthopedic Medicine & Surgery (AREA)
Endocrinology (AREA)
Inorganic Chemistry (AREA)
Zoology (AREA)
Physiology (AREA)
Medicinal Preparation (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

UA20040503844A 2001-10-23 2002-10-23 Lysine-containing chewing tablet UA78242C2 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE10152169		2001-10-23
PCT/EP2002/011843 WO2003035027A1 (en)	2001-10-23	2002-10-23	Chewable tablet containing lysine

Publications (1)

Publication Number	Publication Date
UA78242C2 true UA78242C2 (en)	2007-03-15

Family

ID=7703361

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
UA20040503844A UA78242C2 (en)	2001-10-23	2002-10-23	Lysine-containing chewing tablet

Country Status (16)

Country	Link
EP (1)	EP1439818B1 (de)
JP (1)	JP2005506364A (de)
AR (1)	AR036937A1 (de)
AT (1)	ATE285753T1 (de)
BR (1)	BR0213449A (de)
CA (1)	CA2463259C (de)
DE (1)	DE60202489T2 (de)
ES (1)	ES2236589T3 (de)
HU (1)	HUP0402528A2 (de)
MX (1)	MXPA04003717A (de)
PL (1)	PL368342A1 (de)
PT (1)	PT1439818E (de)
RU (1)	RU2324474C2 (de)
UA (1)	UA78242C2 (de)
UY (1)	UY27505A1 (de)
WO (1)	WO2003035027A1 (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
PL1658079T3 (pl) *	2003-08-19	2012-09-28	Pharmaton Sa	Syrop wielowitaminowy dla dzieci lub młodzieży
JP2005272401A (ja) *	2004-03-25	2005-10-06	Tendou Seiyaku Kk	チュアブル錠
US20080039422A1 (en) *	2004-03-30	2008-02-14	Transition Therapeutics Inc.	Vitamin B12-Containing Compositions and Methods of Use
JP4954450B2 (ja) *	2004-06-14	2012-06-13	ビーエーエスエフビューティケアソリューションズフランスエスエーエス	弾性繊維形成の不全、欠損又は無秩序による病状に対処するための、リシルオキシダーゼのアイソフォームの活性の誘導
US8491937B2 (en) *	2007-02-15	2013-07-23	Wyeth Llc	Stability in vitamin and mineral supplements
DK2142011T3 (da) *	2007-02-23	2011-04-18	Brain Biotechnology Res & Information Network Ag	Fremgangsmåde til smagsmodulering af stofsammensætninger, der indeholder mindst ét højintensitetssødemiddel (HIS)
ES2788078T3 (es) *	2007-03-14	2020-10-20	Vetinnov	Producto apetecible
RU2391109C1 (ru) *	2008-12-09	2010-06-10	Открытое Акционерное Общество "Инвестиционная Финансовая Группа "Гленик-М"	Средство лечения онкологических заболеваний с использованием изотопа кальций-41
DE202012103733U1 (de)	2012-09-28	2012-11-15	Reiner Rittinghausen	Zusammensetzung zur nutritiven Ergänzung oder Behandlung bei Herpes
EP2978431A4 (de) *	2013-03-27	2016-08-24	Psm Healthcare Ltd	Stabilisierte vitamin-d-formulierungen
EP3777566B1 (de)	2014-09-25	2024-03-13	Nutritional Growth Solutions LTD	Nahrungsergänzungsmittel zur wachstumsförderung für jugendliche in der vorpubertät
CN104688774A (zh) *	2015-02-17	2015-06-10	胡梨芳	包含手性异构化合物的赖氨酸磷酸氢钙药物组合物及其用途
JP6812405B2 (ja) *	2015-07-12	2021-01-13	ツェーエフエスオー・ゲーエムベーハー	コレカルシフェロール硫酸塩及びビタミンｄ欠乏症の処置のためのこれらの使用
EP3213747B1 (de) *	2016-03-04	2019-02-13	Laboratorio Reig Jofre S.A.	Tabletten mit hohem gehalt an wirkstoffen zur behandlung von haarverlust oder zur anregung ihres wachstums
CN107854457A (zh) *	2016-09-22	2018-03-30	刘力	包括手性异构化合物的葡萄糖酸钙锌组合物及其用途
US11547688B2 (en)	2019-08-22	2023-01-10	Nodari Rizun	Amino acid compositions and methods of manufacturing the compositions
JP7612148B2 (ja) *	2020-11-09	2025-01-14	株式会社ファンケル	変色が抑制された経口組成物及びその変色抑制方法

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Publication number	Priority date	Publication date	Assignee	Title
US2887437A (en) *	1956-08-22	1959-05-19	Pfizer & Co C	Palatable vitamin tablet containing an amino acid
FR2215950A2 (en) *	1973-02-01	1974-08-30	Union Pharma Scient Appl	Carbonated lysine - as carbonate source in effervescent compositions
US3970750A (en) *	1974-10-08	1976-07-20	Sandoz, Inc.	Effervescent potassium chloride composition
JPH06227974A (ja) *	1993-01-29	1994-08-16	Kyowa Hakko Kogyo Co Ltd	栄養組成物
US20020081360A1 (en) *	2000-12-27	2002-06-27	Andreas Burgard	Salts of L-amino acid having improved taste and their preparation

2002
- 2002-10-21 UY UY27505A patent/UY27505A1/es not_active Application Discontinuation
- 2002-10-23 WO PCT/EP2002/011843 patent/WO2003035027A1/en not_active Ceased
- 2002-10-23 RU RU2004115755/15A patent/RU2324474C2/ru not_active IP Right Cessation
- 2002-10-23 AT AT02774744T patent/ATE285753T1/de active
- 2002-10-23 ES ES02774744T patent/ES2236589T3/es not_active Expired - Lifetime
- 2002-10-23 BR BR0213449-7A patent/BR0213449A/pt not_active Application Discontinuation
- 2002-10-23 AR ARP020104002A patent/AR036937A1/es unknown
- 2002-10-23 PL PL02368342A patent/PL368342A1/xx unknown
- 2002-10-23 JP JP2003537594A patent/JP2005506364A/ja active Pending
- 2002-10-23 EP EP02774744A patent/EP1439818B1/de not_active Expired - Lifetime
- 2002-10-23 PT PT02774744T patent/PT1439818E/pt unknown
- 2002-10-23 UA UA20040503844A patent/UA78242C2/uk unknown
- 2002-10-23 MX MXPA04003717A patent/MXPA04003717A/es active IP Right Grant
- 2002-10-23 DE DE60202489T patent/DE60202489T2/de not_active Expired - Lifetime
- 2002-10-23 CA CA2463259A patent/CA2463259C/en not_active Expired - Fee Related
- 2002-10-23 HU HU0402528A patent/HUP0402528A2/hu unknown

Also Published As

Publication number	Publication date
BR0213449A (pt)	2004-11-09
RU2004115755A (ru)	2005-04-10
PL368342A1 (en)	2005-03-21
AR036937A1 (es)	2004-10-13
CA2463259A1 (en)	2003-05-01
WO2003035027A1 (en)	2003-05-01
DE60202489D1 (de)	2005-02-03
CA2463259C (en)	2011-01-04
RU2324474C2 (ru)	2008-05-20
ES2236589T3 (es)	2005-07-16
EP1439818B1 (de)	2004-12-29
HUP0402528A2 (hu)	2005-07-28
JP2005506364A (ja)	2005-03-03
ATE285753T1 (de)	2005-01-15
UY27505A1 (es)	2003-06-30
PT1439818E (pt)	2005-03-31
EP1439818A1 (de)	2004-07-28
DE60202489T2 (de)	2006-01-05
MXPA04003717A (es)	2004-07-30

Publication	Publication Date	Title
UA78242C2 (en)	2007-03-15	Lysine-containing chewing tablet
Howard et al.	1999	Drugs and breastfeeding
TWI407963B (zh)	2013-09-11	Contains the composition of riboflavin and sesamin
AU3666497A (en)	1998-02-09	Appetite suppression
EP3115047B1 (de)	2020-05-06	Debilitätsprävention
US20100190739A1 (en)	2010-07-29	Rapidly Dissolving Vitamin Formulation and Methods of Using the Same
WO2004095946A2 (en)	2004-11-11	Medical food tablets containing free amino acids
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JP2008530015A (ja)	2008-08-07	栄養補充のための組成物および方法
JP2019089842A (ja)	2019-06-13	頭痛予防用組成物
AU2002310212B2 (en)	2006-09-14	Method and composition for enhancing sexual desire
US7575760B2 (en)	2009-08-18	Chewable tablet containing lysine
US20040043442A1 (en)	2004-03-04	Use of betaine in functional products having blood pressure lowering effects
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JP2008088101A (ja)	2008-04-17	抗疲労剤
US20040192587A9 (en)	2004-09-30	Zinc formulations as a prophylactic treatment for the common cold
WO2003068214A1 (en)	2003-08-21	Novel preventive for infections