UA80116C2 - Amino acids with affinity for the alpha-2-delta-protein - Google Patents

Amino acids with affinity for the alpha-2-delta-protein Download PDF

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Publication number
UA80116C2
UA80116C2 UA20040907854A UA20040907854A UA80116C2 UA 80116 C2 UA80116 C2 UA 80116C2 UA 20040907854 A UA20040907854 A UA 20040907854A UA 20040907854 A UA20040907854 A UA 20040907854A UA 80116 C2 UA80116 C2 UA 80116C2
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UA
Ukraine
Prior art keywords
acid
amino
disorders
aminomethyl
alkyl
Prior art date
Application number
UA20040907854A
Other languages
English (en)
Ukrainian (uk)
Inventor
Nancy Sue Barta
Jacob Bradley Schwarz
Andrew John Thorpe
David Juergen Wustrow
Original Assignee
Warner Lambert Co
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Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=28675482&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=UA80116(C2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Warner Lambert Co filed Critical Warner Lambert Co
Publication of UA80116C2 publication Critical patent/UA80116C2/uk

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/06Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton
    • C07C229/08Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to hydrogen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
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    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/28Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and containing rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/34Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
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    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
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    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
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    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/12Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14The ring being saturated
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
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  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Addiction (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Endocrinology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Hematology (AREA)
  • Rheumatology (AREA)
  • Psychology (AREA)
  • Immunology (AREA)
  • Dermatology (AREA)
  • Hospice & Palliative Care (AREA)
  • Reproductive Health (AREA)
  • Obesity (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Nutrition Science (AREA)
  • Urology & Nephrology (AREA)
  • Anesthesiology (AREA)
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UA20040907854A 2002-03-28 2003-03-17 Amino acids with affinity for the alpha-2-delta-protein UA80116C2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US36841302P 2002-03-28 2002-03-28
PCT/IB2003/000976 WO2003082807A2 (en) 2002-03-28 2003-03-17 Amino acids with affinity for the alpha-2-delta-protein

Publications (1)

Publication Number Publication Date
UA80116C2 true UA80116C2 (en) 2007-08-27

Family

ID=28675482

Family Applications (2)

Application Number Title Priority Date Filing Date
UAA200507455A UA80018C2 (en) 2002-03-28 2003-03-17 Alpha-2-delta-proteins related aminoacids
UA20040907854A UA80116C2 (en) 2002-03-28 2003-03-17 Amino acids with affinity for the alpha-2-delta-protein

Family Applications Before (1)

Application Number Title Priority Date Filing Date
UAA200507455A UA80018C2 (en) 2002-03-28 2003-03-17 Alpha-2-delta-proteins related aminoacids

Country Status (42)

Country Link
US (3) US7064147B2 (sr)
EP (2) EP1614675A3 (sr)
JP (2) JP3831379B2 (sr)
KR (2) KR100694719B1 (sr)
CN (2) CN1817854A (sr)
AP (1) AP1791A (sr)
AR (2) AR039154A1 (sr)
AU (1) AU2003208538B2 (sr)
BR (1) BR0308814A (sr)
CA (1) CA2480872C (sr)
CR (1) CR7501A (sr)
CU (1) CU23331B7 (sr)
CY (1) CY1109304T1 (sr)
DE (1) DE60328469D1 (sr)
DK (1) DK1492761T3 (sr)
EA (2) EA200501497A1 (sr)
EC (1) ECSP045319A (sr)
ES (1) ES2327910T3 (sr)
GE (2) GEP20074123B (sr)
GT (2) GT200300072AA (sr)
HR (2) HRP20040891A2 (sr)
IL (2) IL164110A0 (sr)
IS (2) IS7451A (sr)
MA (1) MA27188A1 (sr)
MX (1) MXPA04009373A (sr)
MY (1) MY131424A (sr)
NI (1) NI200300043A (sr)
NO (2) NO20044614L (sr)
NZ (2) NZ535364A (sr)
OA (1) OA12795A (sr)
PA (1) PA8570001A1 (sr)
PE (1) PE20040349A1 (sr)
PL (1) PL209750B1 (sr)
PT (1) PT1492761E (sr)
RS (2) RS83604A (sr)
SI (1) SI1492761T1 (sr)
TN (1) TNSN04186A1 (sr)
TW (1) TWI225864B (sr)
UA (2) UA80018C2 (sr)
UY (1) UY27738A1 (sr)
WO (1) WO2003082807A2 (sr)
ZA (1) ZA200407536B (sr)

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DE10129693A1 (de) * 2001-06-22 2003-01-02 Jan Loock Verfahren zur extrakorporalen qualitativen und/oder quantitativen Erfassung neurotoxischer Substanzen im Blutplasma eines Individuums
NI200300043A (es) * 2002-03-28 2003-11-05 Warner Lambert Co AMINOACIDOS CON AFINIDAD POR LA PROTEINA a2DELTA.
US7419981B2 (en) 2002-08-15 2008-09-02 Pfizer Inc. Synergistic combinations of an alpha-2-delta ligand and a cGMP phosphodieterse 5 inhibitor
CA2451267A1 (en) 2002-12-13 2004-06-13 Warner-Lambert Company Llc Pharmaceutical uses for alpha2delta ligands
EP1680125A1 (en) * 2003-07-02 2006-07-19 Warner-Lambert Company LLC Combination of an allosteric inhibitor of matrix metalloproteinase-13 and a ligand to an alpha-2-delta receptor
KR20070039986A (ko) * 2003-09-25 2007-04-13 워너-램버트 캄파니 엘엘씨 알파2델타-단백질에 대한 친화성을 갖는 아미노산
KR100774625B1 (ko) * 2003-09-25 2007-11-08 워너-램버트 캄파니 엘엘씨 치료제 베타 아미노산
ATE371496T1 (de) * 2004-03-12 2007-09-15 Warner Lambert Co C1-symmetrische bisphosphinliganden und deren verwendung bei der asymmetrischen synthese von pregabalin
CA2573128A1 (en) * 2004-07-09 2006-01-26 Warner-Lambert Company Llc Preparation of beta-amino acids having affinity for the alpha-2-delta protein
WO2006092692A1 (en) * 2005-03-01 2006-09-08 Pfizer Limited Use of combinations of pde7 inhibitors and alpha-2-delty ligands for the treatment of neuropathic pain
WO2006100568A1 (en) * 2005-03-24 2006-09-28 Pharmacia & Upjohn Company Llc Preparation of optically pure beta-amino acids having affinity for the alpha-2-delta protein
WO2007052134A1 (en) * 2005-11-04 2007-05-10 Pfizer Limited (2s)-2-aminomethyl-5-ethyl heptanoic acid its pharmaceutical use
CA2629896A1 (en) * 2005-11-17 2007-05-24 Pfizer Limited Isocystene derivatives for the treatment of pain
RU2008135907A (ru) * 2006-03-06 2010-04-20 Пфайзер Продактс Инк. (Us) Альфа-2-дельта лиганды для невосстановительного сна
AR061728A1 (es) * 2006-06-30 2008-09-17 Pfizer Prod Inc Composicion para tratamiento usando compuestos selectivos alfa-2-delta-1
US20110124705A1 (en) * 2009-11-24 2011-05-26 Xenoport, Inc. Prodrugs of alpha-2-delta ligands, pharmaceutical compositions and uses thereof
PL2710007T3 (pl) 2011-05-17 2020-06-01 The Regents Of The University Of California Inhibitory kinazy
US8962831B2 (en) 2011-05-17 2015-02-24 Principia Biopharma Inc. Tyrosine kinase inhibitors
US9376438B2 (en) 2011-05-17 2016-06-28 Principia Biopharma, Inc. Pyrazolopyrimidine derivatives as tyrosine kinase inhibitors
CN103164756A (zh) * 2011-12-12 2013-06-19 苏州艾隆科技有限公司 贵重药品的管理方法及其系统
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