UA85589C2 - Способ получения производных замещенных тетралинов и замещенных инданов - Google Patents

Способ получения производных замещенных тетралинов и замещенных инданов

Info

Publication number
UA85589C2
UA85589C2 UAA200611177A UAA200611177A UA85589C2 UA 85589 C2 UA85589 C2 UA 85589C2 UA A200611177 A UAA200611177 A UA A200611177A UA A200611177 A UAA200611177 A UA A200611177A UA 85589 C2 UA85589 C2 UA 85589C2
Authority
UA
Ukraine
Prior art keywords
substituted
preparation
tetralin
indane derivatives
derivatives
Prior art date
Application number
UAA200611177A
Other languages
English (en)
Ukrainian (uk)
Inventor
Фен Жанг-Пласкет
Хуа Жонг
Френк Виллани
Original Assignee
Янссен Фармацевтика Н.В.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Янссен Фармацевтика Н.В. filed Critical Янссен Фармацевтика Н.В.
Publication of UA85589C2 publication Critical patent/UA85589C2/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
    • C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/52—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00—Compounds containing amino groups bound to a carbon skeleton
    • C07C211/01—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
    • C07C211/26—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring
    • C07C211/27—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring having amino groups linked to the six-membered aromatic ring by saturated carbon chains
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C303/00—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides
    • C07C303/02—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of sulfonic acids or halides thereof
    • C07C303/04—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of sulfonic acids or halides thereof by substitution of hydrogen atoms by sulfo or halosulfonyl groups
    • C07C303/08—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of sulfonic acids or halides thereof by substitution of hydrogen atoms by sulfo or halosulfonyl groups by reaction with halogenosulfonic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C319/00—Preparation of thiols, sulfides, hydropolysulfides or polysulfides
    • C07C319/02—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of thiols
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C319/00—Preparation of thiols, sulfides, hydropolysulfides or polysulfides
    • C07C319/14—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C319/00—Preparation of thiols, sulfides, hydropolysulfides or polysulfides
    • C07C319/14—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides
    • C07C319/20—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides by reactions not involving the formation of sulfide groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C319/00—Preparation of thiols, sulfides, hydropolysulfides or polysulfides
    • C07C319/26—Separation; Purification; Stabilisation; Use of additives
    • C07C319/28—Separation; Purification
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/04—One of the condensed rings being a six-membered aromatic ring
    • C07C2602/08—One of the condensed rings being a six-membered aromatic ring the other ring being five-membered, e.g. indane
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/04—One of the condensed rings being a six-membered aromatic ring
    • C07C2602/10—One of the condensed rings being a six-membered aromatic ring the other ring being six-membered, e.g. tetraline

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

Abstract

Изобретение относится к новым способам получения производных замещенных тетралинов и замещенных инданов. Изобретение, кроме того, относится к новым способам получения промежуточных соединений при получении производных замещенных тетралинов и замещенных инданов.
UAA200611177A 2004-04-21 2005-04-20 Способ получения производных замещенных тетралинов и замещенных инданов UA85589C2 (ru)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US56415904P 2004-04-21 2004-04-21

Publications (1)

Publication Number Publication Date
UA85589C2 true UA85589C2 (ru) 2009-02-10

Family

ID=34967583

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA200611177A UA85589C2 (ru) 2004-04-21 2005-04-20 Способ получения производных замещенных тетралинов и замещенных инданов

Country Status (20)

Country Link
US (3) US20050240049A1 (ru)
EP (1) EP1745016A1 (ru)
JP (1) JP2007534690A (ru)
KR (1) KR20060133107A (ru)
CN (1) CN101018766A (ru)
AR (1) AR048931A1 (ru)
AU (1) AU2005238485A1 (ru)
BR (1) BRPI0510118A (ru)
CA (1) CA2564558A1 (ru)
CR (1) CR8757A (ru)
EA (1) EA200601927A1 (ru)
EC (1) ECSP066942A (ru)
IL (1) IL178521A0 (ru)
MX (1) MXPA06012288A (ru)
NI (1) NI200600247A (ru)
NO (1) NO20065341L (ru)
TW (1) TW200606139A (ru)
UA (1) UA85589C2 (ru)
WO (1) WO2005105737A1 (ru)
ZA (1) ZA200609613B (ru)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EA009554B1 (ru) * 2002-10-21 2008-02-28 Янссен Фармацевтика Н.В. Замещённые тетралины и инданы и их применение

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU632809B2 (en) 1989-05-25 1993-01-14 Takeda Chemical Industries Ltd. Benzocycloalkane benzopyran and benzothiopyran urea derivatives and production thereof
US5143713A (en) 1990-05-30 1992-09-01 Board Of Regents, The University Of Texas System 99m Tc labeled liposomes
US5708018A (en) 1993-08-06 1998-01-13 Pharmacia & Upjohn Company 2-aminoindans as selective dopamine D3 ligands
GB9606805D0 (en) * 1996-03-30 1996-06-05 Glaxo Wellcome Inc Medicaments
GB9822473D0 (en) * 1998-10-16 1998-12-09 Glaxo Group Ltd Chemical compounds
DE60135742D1 (de) * 2000-05-29 2008-10-23 Kyorin Seiyaku Kk Substituierte phenylpropionsäure-derivate
PL361162A1 (en) 2000-10-05 2004-09-20 Bayer Aktiengesellschaft Propionic acid derivatives with ppar-alpha activating properties
TWI241190B (en) 2001-02-13 2005-10-11 Aventis Pharma Gmbh 4-Fluoro-N-indan-2-yl benzamide and its use as pharmaceutical
EP1360172A1 (en) 2001-02-15 2003-11-12 Pfizer Products Inc. Ppar agonists
WO2002064130A1 (en) * 2001-02-15 2002-08-22 Pfizer Products Inc. Proliferative activator receptor (ppar) compounds
US7348334B2 (en) * 2001-04-09 2008-03-25 Dr. Reddy's Laboratories Limited Monocyclic derivatives of aryl alkanoic acids and their use in medicine: process for their preparation and pharmaceutical compositions containing them
US6548538B2 (en) * 2001-05-22 2003-04-15 Bayer Aktiengesellschaft Propionic acid derivatives
US20030125338A1 (en) * 2001-06-12 2003-07-03 Active Pass Pharmaceuticals, Inc. Compounds, compositions and methods for modulating beta-amyloid production
WO2004037778A1 (en) * 2002-10-21 2004-05-06 Janssen Pharmaceutica, N.V. Substituted tetralins and indanes
EA009554B1 (ru) * 2002-10-21 2008-02-28 Янссен Фармацевтика Н.В. Замещённые тетралины и инданы и их применение
US20060247314A1 (en) * 2002-10-21 2006-11-02 Xiaoli Chen Substituted tetralins and indanes
BR0315566A (pt) * 2002-10-21 2005-08-23 Janssen Pharmaceutica Nv Tetralinas e indanos substituìdos
US20060094786A1 (en) * 2002-10-21 2006-05-04 Xiaoli Chen Treating syndrome X with substituted tetralins and indanes

Also Published As

Publication number Publication date
JP2007534690A (ja) 2007-11-29
US7576238B2 (en) 2009-08-18
MXPA06012288A (es) 2007-03-15
TW200606139A (en) 2006-02-16
CR8757A (es) 2008-11-24
CA2564558A1 (en) 2005-11-10
IL178521A0 (en) 2007-02-11
US20080096962A1 (en) 2008-04-24
AU2005238485A1 (en) 2005-11-10
BRPI0510118A (pt) 2007-09-25
WO2005105737A1 (en) 2005-11-10
US20090326258A1 (en) 2009-12-31
EA200601927A1 (ru) 2007-04-27
ECSP066942A (es) 2006-12-20
KR20060133107A (ko) 2006-12-22
CN101018766A (zh) 2007-08-15
NO20065341L (no) 2007-01-18
EP1745016A1 (en) 2007-01-24
ZA200609613B (en) 2008-04-30
US20050240049A1 (en) 2005-10-27
NI200600247A (es) 2007-07-24
AR048931A1 (es) 2006-06-14

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