UA87434C2 - Циклоалкильные соединения в качестве ингибиторов функции калиевых каналов - Google Patents

Циклоалкильные соединения в качестве ингибиторов функции калиевых каналов

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Publication number
UA87434C2
UA87434C2 UA20040807176A UA20040807176A UA87434C2 UA 87434 C2 UA87434 C2 UA 87434C2 UA 20040807176 A UA20040807176 A UA 20040807176A UA 20040807176 A UA20040807176 A UA 20040807176A UA 87434 C2 UA87434 C2 UA 87434C2
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UA
Ukraine
Prior art keywords
inhibitors
potassium channel
channel function
compounds
cycloalkyl
Prior art date
Application number
UA20040807176A
Other languages
English (en)
Ukrainian (uk)
Inventor
Джон Ллойд
Йун Т. Джеон
Хеазер Финлей
Лин Ян
Майкл Ф. Гросс
Серж Боудоин
Original Assignee
Бристол-Майерс Сквибб Компани
Айседжен, Инк
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Publication date
Application filed by Бристол-Майерс Сквибб Компани, Айседжен, Инк filed Critical Бристол-Майерс Сквибб Компани
Publication of UA87434C2 publication Critical patent/UA87434C2/ru

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Abstract

Изобретение касается новых циклоалкильных соединений, которые могут применяться в качестве ингибиторов функции калиевых каналов (в частности, в качестве ингибиторов подсемейства КІ потенциал-управляемых K+-каналов, а именно в качестве ингибиторов каналов К1,5, которые были связаны с сверхбыстро активирующим К+-потоком Ізадержанного выпрямителя), применения этих соединений в профилактике и лечении аритмии и І-ассоциированных расстройств, а также фармацевтических композиций, которые содержат такие соединения.
UA20040807176A 2002-02-01 2003-01-31 Циклоалкильные соединения в качестве ингибиторов функции калиевых каналов UA87434C2 (ru)

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CN100558697C (zh) 2009-11-11
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EP2253328A1 (en) 2010-11-24
WO2003063797A8 (en) 2004-12-16
JP5148646B2 (ja) 2013-02-20
US20070142333A1 (en) 2007-06-21
RU2343143C2 (ru) 2009-01-10
JP4598397B2 (ja) 2010-12-15
HRP20040667A2 (en) 2005-08-31
BR0307329A (pt) 2006-04-11
ZA200405905B (en) 2006-05-31
US20040072880A1 (en) 2004-04-15
AU2003210817B9 (en) 2009-10-29
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US7202253B2 (en) 2007-04-10
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