UA87674C2 - Способ получения нитрата бутоконазола - Google Patents

Способ получения нитрата бутоконазола

Info

Publication number
UA87674C2
UA87674C2 UAA200609221A UAA200609221A UA87674C2 UA 87674 C2 UA87674 C2 UA 87674C2 UA A200609221 A UAA200609221 A UA A200609221A UA A200609221 A UAA200609221 A UA A200609221A UA 87674 C2 UA87674 C2 UA 87674C2
Authority
UA
Ukraine
Prior art keywords
preparation
butoconazole nitrate
particles
diameter
nitrate
Prior art date
Application number
UAA200609221A
Other languages
English (en)
Ukrainian (uk)
Inventor
Ласло Цибула
Ласло Добай
Папп Эва Веркне
Багдь Юдит Надьне
Ференц Шебок
Original Assignee
Рихтер Гедеон Ведьесети Дьяр Рт.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Рихтер Гедеон Ведьесети Дьяр Рт. filed Critical Рихтер Гедеон Ведьесети Дьяр Рт.
Publication of UA87674C2 publication Critical patent/UA87674C2/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C07D233/60—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms with hydrocarbon radicals, substituted by oxygen or sulfur atoms, attached to ring nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Inorganic Compounds Of Heavy Metals (AREA)

Abstract

Объектом этого изобретения является способ получения нитрата бутоконазола высокой степени чистоты формулы (І), который содержит максимум 0,1 масс. % химических примесей, в котором, по крайней мере, 95 % частиц вещества имеют диаметр меньше 75 мкм, в то время как, по крайней мере,99 % частиц имеют диаметр менее 250 мкм.
UAA200609221A 2004-01-27 2005-01-25 Способ получения нитрата бутоконазола UA87674C2 (ru)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU0400270A HUP0400270A3 (en) 2004-01-27 2004-01-27 High purity butoconazole nitrate having a predetermined particle size and process for the production of the same

Publications (1)

Publication Number Publication Date
UA87674C2 true UA87674C2 (ru) 2009-08-10

Family

ID=89981937

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA200609221A UA87674C2 (ru) 2004-01-27 2005-01-25 Способ получения нитрата бутоконазола

Country Status (9)

Country Link
US (1) US7625935B2 (ru)
EP (2) EP1903035A3 (ru)
JP (1) JP4795973B2 (ru)
DE (1) DE602005015417D1 (ru)
EA (1) EA009238B1 (ru)
HU (1) HUP0400270A3 (ru)
NO (1) NO20063805L (ru)
UA (1) UA87674C2 (ru)
WO (1) WO2005070897A1 (ru)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102649796A (zh) * 2011-02-24 2012-08-29 四川滇虹医药开发有限公司 一种硝酸布康唑中间体的制备方法
CN105175338B (zh) * 2015-10-09 2018-03-23 株洲千金药业股份有限公司 一种工业化生产硝酸布康唑中间体的方法
CN105198814B (zh) * 2015-10-09 2018-03-20 株洲千金药业股份有限公司 一种工业化生产硝酸布康唑中间体的方法
CN105218456B (zh) * 2015-10-09 2018-07-03 株洲千金药业股份有限公司 一种工业化生产硝酸布康唑的方法
CN105175341B (zh) * 2015-10-09 2017-12-26 株洲千金药业股份有限公司 一种工业化合成硝酸布康唑中间体的方法
CN105218455B (zh) * 2015-10-09 2018-07-03 株洲千金药业股份有限公司 一种工业化连续生产硝酸布康唑的方法
CN105198816B (zh) * 2015-10-09 2018-05-01 株洲千金药业股份有限公司 一种工业化生产硝酸布康唑的方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL184160C (nl) * 1977-01-10 1989-05-01 Syntex Inc Tegen schimmels werkzame imidazool-derivaten, preparaten die ze bevatten en werkwijze voor de bereiding daarvan.

Also Published As

Publication number Publication date
EP1709005A1 (en) 2006-10-11
WO2005070897A1 (en) 2005-08-04
US7625935B2 (en) 2009-12-01
JP2007519699A (ja) 2007-07-19
EP1903035A2 (en) 2008-03-26
EA009238B1 (ru) 2007-12-28
HUP0400270A3 (en) 2007-09-28
HU0400270D0 (en) 2004-04-28
JP4795973B2 (ja) 2011-10-19
US20080221190A1 (en) 2008-09-11
EP1903035A3 (en) 2009-01-07
NO20063805L (no) 2006-08-25
EA200601373A1 (ru) 2006-12-29
DE602005015417D1 (de) 2009-08-27
EP1709005B1 (en) 2009-07-15
HUP0400270A2 (hu) 2005-12-28

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