UA87845C2 - Производные тиенопиридинона и способ лечения расстройств нервной системы - Google Patents
Производные тиенопиридинона и способ лечения расстройств нервной системыInfo
- Publication number
- UA87845C2 UA87845C2 UAA200613298A UAA200613298A UA87845C2 UA 87845 C2 UA87845 C2 UA 87845C2 UA A200613298 A UAA200613298 A UA A200613298A UA A200613298 A UAA200613298 A UA A200613298A UA 87845 C2 UA87845 C2 UA 87845C2
- Authority
- UA
- Ukraine
- Prior art keywords
- disorders
- methods
- treatment
- nervous system
- system disorders
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 208000012902 Nervous system disease Diseases 0.000 title 1
- 108091032151 5-hydroxytryptamine receptor family Proteins 0.000 abstract 2
- 206010047700 Vomiting Diseases 0.000 abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- 102000040125 5-hydroxytryptamine receptor family Human genes 0.000 abstract 1
- 208000024827 Alzheimer disease Diseases 0.000 abstract 1
- 208000019901 Anxiety disease Diseases 0.000 abstract 1
- 206010003658 Atrial Fibrillation Diseases 0.000 abstract 1
- 206010010774 Constipation Diseases 0.000 abstract 1
- 208000010228 Erectile Dysfunction Diseases 0.000 abstract 1
- 208000019454 Feeding and Eating disease Diseases 0.000 abstract 1
- 102000014630 G protein-coupled serotonin receptor activity proteins Human genes 0.000 abstract 1
- 208000007882 Gastritis Diseases 0.000 abstract 1
- 208000018522 Gastrointestinal disease Diseases 0.000 abstract 1
- 208000032382 Ischaemic stroke Diseases 0.000 abstract 1
- 208000019695 Migraine disease Diseases 0.000 abstract 1
- 206010028813 Nausea Diseases 0.000 abstract 1
- 208000004756 Respiratory Insufficiency Diseases 0.000 abstract 1
- 206010038678 Respiratory depression Diseases 0.000 abstract 1
- 206010046543 Urinary incontinence Diseases 0.000 abstract 1
- 230000036506 anxiety Effects 0.000 abstract 1
- 206010003119 arrhythmia Diseases 0.000 abstract 1
- 230000006793 arrhythmia Effects 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 208000010877 cognitive disease Diseases 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000035475 disorder Diseases 0.000 abstract 1
- 201000006549 dyspepsia Diseases 0.000 abstract 1
- 230000030136 gastric emptying Effects 0.000 abstract 1
- 208000021302 gastroesophageal reflux disease Diseases 0.000 abstract 1
- 201000001881 impotence Diseases 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 208000002551 irritable bowel syndrome Diseases 0.000 abstract 1
- 230000001404 mediated effect Effects 0.000 abstract 1
- 206010027599 migraine Diseases 0.000 abstract 1
- 230000008693 nausea Effects 0.000 abstract 1
- 239000004031 partial agonist Substances 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 239000000018 receptor agonist Substances 0.000 abstract 1
- 229940044601 receptor agonist Drugs 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
- 230000008673 vomiting Effects 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Abstract
Изобретение касается агонистов и неполных агонистов рецептора 5-НТ.Раскрыты новые производные тиенопиридинона, представленные формулой І, их синтез и применение для лечения заболеваний, непосредственно или косвенно опосредованных рецепторами 5-НТ. Такие состояния включают болезнь Альцгеймера, расстройства познавательной способности, синдром раздраженной толстой кишки, тошноту, рвоту, срыгивание, прокинезию, гастроэзофагеальный рефлюкс, неязвенную диспепсию, депрессию, тревогу, недержание мочи, мигрень, аритмию, фибрилляцию предсердий, ишемический удар, гастрит, нарушение опорожнения кишечника, расстройства приема пищи, желудочно-кишечные расстройства, запор, эректильную дисфункцию и угнетение дыхания.Включены также способы получения и новые промежуточные продукты и их фармацевтически приемлемые соли.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US57185204P | 2004-05-17 | 2004-05-17 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UA87845C2 true UA87845C2 (ru) | 2009-08-25 |
Family
ID=38716194
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UAA200613298A UA87845C2 (ru) | 2004-05-17 | 2005-05-16 | Производные тиенопиридинона и способ лечения расстройств нервной системы |
Country Status (3)
| Country | Link |
|---|---|
| CN (1) | CN101031299A (ru) |
| UA (1) | UA87845C2 (ru) |
| ZA (1) | ZA200609213B (ru) |
-
2005
- 2005-05-16 CN CN 200580016769 patent/CN101031299A/zh active Pending
- 2005-05-16 UA UAA200613298A patent/UA87845C2/ru unknown
-
2006
- 2006-11-06 ZA ZA200609213A patent/ZA200609213B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CN101031299A (zh) | 2007-09-05 |
| ZA200609213B (en) | 2007-10-31 |
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