UA91677C2 - Макроциклические соединения как ингибиторы вирусной репликации - Google Patents
Макроциклические соединения как ингибиторы вирусной репликацииInfo
- Publication number
- UA91677C2 UA91677C2 UAA200611368A UAA200611368A UA91677C2 UA 91677 C2 UA91677 C2 UA 91677C2 UA A200611368 A UAA200611368 A UA A200611368A UA A200611368 A UAA200611368 A UA A200611368A UA 91677 C2 UA91677 C2 UA 91677C2
- Authority
- UA
- Ukraine
- Prior art keywords
- methods
- inhibitors
- hcv replication
- macrocyclic compounds
- subject compound
- Prior art date
Links
- 239000003112 inhibitor Substances 0.000 title 1
- 150000002678 macrocyclic compounds Chemical class 0.000 title 1
- 230000010076 replication Effects 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 3
- 239000000203 mixture Substances 0.000 abstract 2
- 206010057199 Flaviviral infections Diseases 0.000 abstract 1
- 208000019425 cirrhosis of liver Diseases 0.000 abstract 1
- 208000010710 hepatitis C virus infection Diseases 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US55816104P | 2004-03-30 | 2004-03-30 | |
| PCT/US2005/010494 WO2005095403A2 (en) | 2004-03-30 | 2005-03-29 | Macrocyclic compounds as inhibitors of viral replication |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UA91677C2 true UA91677C2 (ru) | 2010-08-25 |
Family
ID=37955155
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UAA200611368A UA91677C2 (ru) | 2004-03-30 | 2005-03-29 | Макроциклические соединения как ингибиторы вирусной репликации |
Country Status (5)
| Country | Link |
|---|---|
| CN (1) | CN1938311A (es) |
| CU (1) | CU20090112A6 (es) |
| TN (1) | TNSN06308A1 (es) |
| UA (1) | UA91677C2 (es) |
| ZA (1) | ZA200608798B (es) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2009034055A1 (en) * | 2007-09-10 | 2009-03-19 | Novartis Forschungsstiftung, Zweigniederlassung | Method for predicting the response of a subject suffering from a viral infection of the liver to an antiviral therapy |
| WO2010033941A1 (en) | 2008-09-22 | 2010-03-25 | Array Biopharma Inc. | Substituted imidazo[1,2b]pyridazine compounds as trk kinase inhibitors |
| MY169791A (en) | 2008-10-22 | 2019-05-15 | Array Biopharma Inc | Substituted pyrazolo [1,5-a] pyrimidine compounds as trk kinase inhibitors |
| PT2401272T (pt) * | 2009-02-27 | 2017-02-28 | Janssen Pharmaceuticals Inc | Sal amorfo de um inibidor macrocíclico de hcv |
| AR077468A1 (es) | 2009-07-09 | 2011-08-31 | Array Biopharma Inc | Compuestos de pirazolo (1,5 -a) pirimidina sustituidos como inhibidores de trk- quinasa |
| KR20120110090A (ko) * | 2009-09-28 | 2012-10-09 | 에프. 호프만-라 로슈 리미티드 | Ｃ형 간염 바이러스 복제의 신규한 마크로시클릭 저해제 |
| AU2011209051B2 (en) * | 2010-01-27 | 2015-01-15 | AB Pharma Ltd. | Polyheterocyclic compounds highly potent as HCV inhibitors |
| ME03376B (me) | 2010-05-20 | 2020-01-20 | Array Biopharma Inc | Makrociklička jedinjenja kао inhibiтori trk kinaze |
| GB201116559D0 (en) * | 2011-09-26 | 2011-11-09 | Univ Leuven Kath | Novel viral replication inhibitors |
| CN113354649B (zh) | 2014-11-16 | 2024-12-10 | 阵列生物制药公司 | 一种新的晶型 |
| EP3368039A1 (en) | 2015-10-26 | 2018-09-05 | The Regents of The University of Colorado, A Body Corporate | Point mutations in trk inhibitor-resistant cancer and methods relating to the same |
| CN107043405B (zh) * | 2016-02-05 | 2021-11-19 | 爱博新药研发(上海)有限公司 | 多环杂环化合物的晶型、其制备方法、应用及组合物 |
| US10045991B2 (en) | 2016-04-04 | 2018-08-14 | Loxo Oncology, Inc. | Methods of treating pediatric cancers |
| FI3439662T3 (fi) | 2016-04-04 | 2024-09-04 | Loxo Oncology Inc | (s)-n-(5-((r)-2-(2,5-difluorifenyyli)pyrrolidin-1-yyli)pyratsolo[1,5-a]pyrimidin-3-yyli)-3-hydroksipyrrolidiini-1-karboksamidin nesteformulaatioita |
| EP3458456B1 (en) | 2016-05-18 | 2020-11-25 | Loxo Oncology Inc. | Preparation of (s)-n-(5-((r)-2-(2,5-difluorophenyl)pyrrolidin-1-yl)pyrazolo[1,5-a]pyrimidin-3-yl)-3-hydroxypyrrolidine-1-carboxamide |
| JOP20190092A1 (ar) | 2016-10-26 | 2019-04-25 | Array Biopharma Inc | عملية لتحضير مركبات بيرازولو[1، 5-a]بيريميدين وأملاح منها |
| JOP20190213A1 (ar) | 2017-03-16 | 2019-09-16 | Array Biopharma Inc | مركبات حلقية ضخمة كمثبطات لكيناز ros1 |
-
2005
- 2005-03-29 CN CN 200580010503 patent/CN1938311A/zh active Pending
- 2005-03-29 UA UAA200611368A patent/UA91677C2/ru unknown
-
2006
- 2006-09-27 TN TNP2006000308A patent/TNSN06308A1/en unknown
- 2006-10-23 ZA ZA200608798A patent/ZA200608798B/xx unknown
-
2009
- 2009-06-24 CU CU20090112A patent/CU20090112A6/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| TNSN06308A1 (en) | 2007-12-03 |
| CN1938311A (zh) | 2007-03-28 |
| CU20090112A6 (es) | 2012-03-15 |
| ZA200608798B (en) | 2008-06-25 |
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