UA92132C2 - Высокоактивные рекомбинантные вирусы гриппа для вакцин и генотерапии - Google Patents

Высокоактивные рекомбинантные вирусы гриппа для вакцин и генотерапии

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Publication number
UA92132C2
UA92132C2 UAA200512619A UAA200512619A UA92132C2 UA 92132 C2 UA92132 C2 UA 92132C2 UA A200512619 A UAA200512619 A UA A200512619A UA A200512619 A UAA200512619 A UA A200512619A UA 92132 C2 UA92132 C2 UA 92132C2
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Prior art keywords
influenza viruses
high titer
vaccines
gene therapy
recombinant influenza
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UAA200512619A
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English (en)
Ukrainian (uk)
Inventor
Йосихиро Каваока
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Висконсин Алюмни Рисьёч Фаундейшн
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Publication of UA92132C2 publication Critical patent/UA92132C2/ru

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    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
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    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C12N7/04—Inactivation or attenuation; Producing viral sub-units
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
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    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
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    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
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    • C12N2760/16011—Orthomyxoviridae
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    • C12N2760/00011—Details
    • C12N2760/16011—Orthomyxoviridae
    • C12N2760/16111—Influenzavirus A, i.e. influenza A virus
    • C12N2760/16141—Use of virus, viral particle or viral elements as a vector
    • C12N2760/16143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

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  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Изобретение относится к композиции, векторам вируса гриппа для продуцирования молекул "минус-нитевой" и " плюс-нитевой" РНК, пригодной для получения высокоактивных вирусов гриппа. Также изобретение относится к способу получения "6+2" реассортативных вирусов гриппа с применением клонированных кДНК и обратной генетики.
UAA200512619A 2003-05-28 2004-05-27 Высокоактивные рекомбинантные вирусы гриппа для вакцин и генотерапии UA92132C2 (ru)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US47379803P 2003-05-28 2003-05-28

Publications (1)

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UA92132C2 true UA92132C2 (ru) 2010-10-11

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UAA200512619A UA92132C2 (ru) 2003-05-28 2004-05-27 Высокоактивные рекомбинантные вирусы гриппа для вакцин и генотерапии

Country Status (18)

Country Link
US (1) US8475806B2 (ru)
EP (1) EP1631663B1 (ru)
JP (2) JP5215561B2 (ru)
KR (1) KR100908757B1 (ru)
CN (1) CN1826407B (ru)
AU (1) AU2004249133B2 (ru)
BR (1) BRPI0410702B1 (ru)
CA (1) CA2525953C (ru)
EA (1) EA012965B1 (ru)
ES (1) ES2593082T3 (ru)
HU (1) HUE030962T2 (ru)
IL (2) IL171831A (ru)
MX (1) MX342639B (ru)
NO (1) NO341506B1 (ru)
NZ (1) NZ543446A (ru)
UA (1) UA92132C2 (ru)
WO (1) WO2004112831A2 (ru)
ZA (1) ZA200510309B (ru)

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EP1631663B1 (en) 2016-08-24
IL238584A0 (en) 2015-06-30
EA012965B1 (ru) 2010-02-26
IL171831A (en) 2015-05-31
EA200501890A1 (ru) 2006-06-30
KR100908757B1 (ko) 2009-07-22
WO2004112831A3 (en) 2005-03-24
NO20056074L (no) 2006-03-22
JP5695020B2 (ja) 2015-04-01
AU2004249133A1 (en) 2004-12-29
ZA200510309B (en) 2006-08-30
JP2007518395A (ja) 2007-07-12
MX342639B (es) 2016-10-07
NZ543446A (en) 2008-06-30
US8475806B2 (en) 2013-07-02
HK1082769A1 (zh) 2006-06-16
AU2004249133B2 (en) 2009-05-28
US20050003349A1 (en) 2005-01-06
CN1826407B (zh) 2013-09-11
EP1631663A2 (en) 2006-03-08
ES2593082T3 (es) 2016-12-05
KR20060016095A (ko) 2006-02-21
HUE030962T2 (en) 2017-06-28
CN1826407A (zh) 2006-08-30
NO341506B1 (no) 2017-11-27
JP2013059346A (ja) 2013-04-04
WO2004112831A2 (en) 2004-12-29
JP5215561B2 (ja) 2013-06-19
BRPI0410702A (pt) 2006-06-13
IL238584B (en) 2020-06-30
BRPI0410702B1 (pt) 2022-04-12
CA2525953C (en) 2023-10-10
CA2525953A1 (en) 2004-12-29

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