UA92146C2 - Стабилизированная жидкая композиция, которая содержит интерферон - Google Patents
Стабилизированная жидкая композиция, которая содержит интерферонInfo
- Publication number
- UA92146C2 UA92146C2 UAA200612406A UAA200612406A UA92146C2 UA 92146 C2 UA92146 C2 UA 92146C2 UA A200612406 A UAA200612406 A UA A200612406A UA A200612406 A UAA200612406 A UA A200612406A UA 92146 C2 UA92146 C2 UA 92146C2
- Authority
- UA
- Ukraine
- Prior art keywords
- concentration
- liquid formulations
- stabilized interferon
- interferon liquid
- poloxamer
- Prior art date
Links
- 102000014150 Interferons Human genes 0.000 title 1
- 108010050904 Interferons Proteins 0.000 title 1
- 229940079322 interferon Drugs 0.000 title 1
- 239000012669 liquid formulation Substances 0.000 title 1
- CTKXFMQHOOWWEB-UHFFFAOYSA-N Ethylene oxide/propylene oxide copolymer Chemical compound CCCOC(C)COCCO CTKXFMQHOOWWEB-UHFFFAOYSA-N 0.000 abstract 2
- 108010005716 Interferon beta-1a Proteins 0.000 abstract 2
- FFEARJCKVFRZRR-BYPYZUCNSA-N L-methionine Chemical compound CSCC[C@H](N)C(O)=O FFEARJCKVFRZRR-BYPYZUCNSA-N 0.000 abstract 2
- 229960004461 interferon beta-1a Drugs 0.000 abstract 2
- 229930182817 methionine Natural products 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 229920001993 poloxamer 188 Polymers 0.000 abstract 2
- 229940044519 poloxamer 188 Drugs 0.000 abstract 2
- KDXKERNSBIXSRK-UHFFFAOYSA-N Lysine Natural products NCCCCC(N)C(O)=O KDXKERNSBIXSRK-UHFFFAOYSA-N 0.000 abstract 1
- 239000004472 Lysine Substances 0.000 abstract 1
- 239000008351 acetate buffer Substances 0.000 abstract 1
- 239000007864 aqueous solution Substances 0.000 abstract 1
- 239000007788 liquid Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/21—Interferons [IFN]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Gastroenterology & Hepatology (AREA)
- Dermatology (AREA)
- Zoology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Communicable Diseases (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Oncology (AREA)
- Virology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP04076626 | 2004-06-01 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UA92146C2 true UA92146C2 (ru) | 2010-10-11 |
Family
ID=34928261
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UAA200612406A UA92146C2 (ru) | 2004-06-01 | 2005-05-27 | Стабилизированная жидкая композиция, которая содержит интерферон |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US7731948B2 (ru) |
| EP (1) | EP1750751B1 (ru) |
| JP (1) | JP4988562B2 (ru) |
| CN (1) | CN1993139B (ru) |
| AU (1) | AU2005249233B2 (ru) |
| BR (1) | BRPI0510526A (ru) |
| CA (1) | CA2567310A1 (ru) |
| EA (1) | EA010979B1 (ru) |
| ES (1) | ES2418833T3 (ru) |
| IL (1) | IL179620A (ru) |
| MX (1) | MXPA06014078A (ru) |
| NO (1) | NO20065860L (ru) |
| UA (1) | UA92146C2 (ru) |
| WO (1) | WO2005117949A1 (ru) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2547822A1 (en) * | 2003-12-11 | 2005-06-30 | Ares Trading S.A. | Stabilized interferon liquid formulations |
| ZA200609412B (en) | 2004-05-17 | 2008-07-30 | Ares Trading Sa | Hydrogel interferon formulations |
| CA2571800A1 (en) * | 2005-12-23 | 2007-06-23 | Canadian Blood Services | Nitrophenyls and related compounds and thimerosal for the inhibition of immune related cell or tissue destruction |
| TW200806317A (en) * | 2006-03-20 | 2008-02-01 | Wyeth Corp | Methods for reducing protein aggregation |
| WO2008066322A1 (en) * | 2006-11-28 | 2008-06-05 | Daewoong Co., Ltd. | A stable hsa-free and antioxidant-free pharmaceutical composition comprising interferon-beta |
| EP2170268A2 (en) | 2007-06-25 | 2010-04-07 | Amgen, Inc. | Compositions of specific binding agents to hepatocyte growth factor |
| JP5563475B2 (ja) * | 2007-12-20 | 2014-07-30 | メルク セローノ ソシエテ アノニム | Pegインターフェロン−ベータ製剤 |
| NZ602685A (en) * | 2010-03-01 | 2014-10-31 | Cytodyn Inc | Concentrated protein formulations and uses thereof |
| US20120269770A1 (en) * | 2010-11-22 | 2012-10-25 | Mark Brader | Stable Preserved Compositions of Interferon-Beta |
| EP2686002B1 (en) * | 2011-03-15 | 2018-01-24 | Biogen Inc. | Method for reducing flu-like symptoms associated with intramuscular administration of interferon using a fast titration escalating dosing regimen |
| RU2527701C1 (ru) * | 2013-05-24 | 2014-09-10 | Федеральное государственное бюджетное учреждение "Научный центр реконструктивной и восстановительной хирургии" Сибирского отделения Российской академии медицинских наук (ФГБУ "НЦРВХ" СО РАМН) | Способ приготовления средства, обладающего свойством стимуляции регенерации хрящевой, костной, мышечной тканей и способ стимуляции регенерации хрящевой, костной, мышечной тканей с использованием приготовленного средства |
| CN106132983B (zh) | 2014-04-04 | 2021-03-26 | 阿雷斯贸易股份有限公司 | 新型IFN-β蛋白类似物 |
| US9744239B2 (en) | 2015-01-30 | 2017-08-29 | Par Pharmaceutical, Inc. | Vasopressin formulations for use in treatment of hypotension |
| US9925233B2 (en) | 2015-01-30 | 2018-03-27 | Par Pharmaceutical, Inc. | Vasopressin formulations for use in treatment of hypotension |
| US9750785B2 (en) | 2015-01-30 | 2017-09-05 | Par Pharmaceutical, Inc. | Vasopressin formulations for use in treatment of hypotension |
| US9937223B2 (en) | 2015-01-30 | 2018-04-10 | Par Pharmaceutical, Inc. | Vasopressin formulations for use in treatment of hypotension |
| US9744209B2 (en) | 2015-01-30 | 2017-08-29 | Par Pharmaceutical, Inc. | Vasopressin formulations for use in treatment of hypotension |
| US9687526B2 (en) | 2015-01-30 | 2017-06-27 | Par Pharmaceutical, Inc. | Vasopressin formulations for use in treatment of hypotension |
| CN114053397B (zh) * | 2022-01-17 | 2022-12-20 | 北京三元基因药业股份有限公司 | 一种稳定的干扰素多剂量注射液及其制备方法 |
| CN120549858A (zh) * | 2025-07-31 | 2025-08-29 | 长春生物制品研究所有限责任公司 | 重组人干扰素α1b溶液及其制备方法与应用 |
Family Cites Families (37)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6936694B1 (en) | 1982-05-06 | 2005-08-30 | Intermune, Inc. | Manufacture and expression of large structural genes |
| DE3380726D1 (en) | 1982-06-24 | 1989-11-23 | Japan Chem Res | Long-acting composition |
| US4737462A (en) * | 1982-10-19 | 1988-04-12 | Cetus Corporation | Structural genes, plasmids and transformed cells for producing cysteine depleted muteins of interferon-β |
| US4588585A (en) | 1982-10-19 | 1986-05-13 | Cetus Corporation | Human recombinant cysteine depleted interferon-β muteins |
| US4469228A (en) * | 1983-05-31 | 1984-09-04 | Schering Corporation | Interferon kit |
| US4636383A (en) | 1984-08-29 | 1987-01-13 | Schering Corporation | Interferon-cyclaradine combination |
| US4959314A (en) | 1984-11-09 | 1990-09-25 | Cetus Corporation | Cysteine-depleted muteins of biologically active proteins |
| US5116943A (en) * | 1985-01-18 | 1992-05-26 | Cetus Corporation | Oxidation-resistant muteins of Il-2 and other protein |
| US5017691A (en) | 1986-07-03 | 1991-05-21 | Schering Corporation | Mammalian interleukin-4 |
| US4879111A (en) | 1986-04-17 | 1989-11-07 | Cetus Corporation | Treatment of infections with lymphokines |
| US4965195A (en) * | 1987-10-26 | 1990-10-23 | Immunex Corp. | Interleukin-7 |
| US4904584A (en) | 1987-12-23 | 1990-02-27 | Genetics Institute, Inc. | Site-specific homogeneous modification of polypeptides |
| IT1244511B (it) | 1991-04-15 | 1994-07-15 | Isi Ist Sierovaccinogeno Ital | Idrogeli a base di policarbossilati sintetici e proteine per il rilascio controllato di farmaci e procedimento per la loro preparazione. |
| KR960009385B1 (en) * | 1993-11-24 | 1996-07-18 | Samsung Bp Chemicals Co Ltd | Apparatus and method for wastewater treatment by activated sludge process type |
| IT1272252B (it) * | 1994-05-16 | 1997-06-16 | Applied Research Systems | Formulazioni liquide di interferone beta |
| JP2758154B2 (ja) | 1995-04-06 | 1998-05-28 | エフ・ホフマン−ラ ロシユ アーゲー | インターフェロンを含む液体製剤 |
| ZA9610374B (en) | 1995-12-11 | 1997-06-23 | Elan Med Tech | Cartridge-based drug delivery device |
| JP4642946B2 (ja) * | 1996-12-20 | 2011-03-02 | アルザ コーポレイション | ゲル組成物および方法 |
| US6013253A (en) * | 1997-08-15 | 2000-01-11 | Amgen, Inc. | Treatment of multiple sclerosis using consensus interferon and IL-1 receptor antagonist |
| EP1426058A3 (de) * | 1997-09-23 | 2004-07-28 | Dr. Rentschler Biotechnologie GmbH | Flüssige Interferon-Beta Formulierungen |
| EP1037995A1 (en) * | 1997-12-08 | 2000-09-27 | Genentech, Inc. | Human interferon-epsilon: a type 1 interferon |
| EE05214B1 (et) | 1998-04-28 | 2009-10-15 | Applied Research Systems ARS Holding N.V. | Polool-IFN- β konjugaat, selle valmistamismeetod ja farmatseutiline kompositsioon |
| US6143314A (en) | 1998-10-28 | 2000-11-07 | Atrix Laboratories, Inc. | Controlled release liquid delivery compositions with low initial drug burst |
| US7754855B1 (en) | 1999-07-13 | 2010-07-13 | Bolder Biotechnology, Inc. | Immunoglobulin fusion proteins |
| US6531122B1 (en) * | 1999-08-27 | 2003-03-11 | Maxygen Aps | Interferon-β variants and conjugates |
| CZ20021186A3 (cs) * | 1999-10-04 | 2002-11-13 | Chiron Corporation | Farmaceutické prostředky obsahující stabilizovaný kapalný polypeptid |
| CN1175901C (zh) | 1999-12-06 | 2004-11-17 | 天津华立达生物工程有限公司 | 一种稳定的干扰素水溶液 |
| US6465425B1 (en) | 2000-02-10 | 2002-10-15 | Alkermes Controlled Therapeutics, Inc. | Microencapsulation and sustained release of biologically active acid-stable or free sulfhydryl-containing proteins |
| US6723606B2 (en) | 2000-06-29 | 2004-04-20 | California Institute Of Technology | Aerosol process for fabricating discontinuous floating gate microelectronic devices |
| KR100396983B1 (ko) | 2000-07-29 | 2003-09-02 | 이강춘 | 고반응성의 가지 달린 고분자 유도체 및 고분자와 단백질또는 펩타이드의 접합체 |
| DK1345593T3 (da) | 2000-12-27 | 2007-12-10 | Ares Trading Sa | Lipidmikropartikler ved kryogen mikronisering |
| US6887462B2 (en) * | 2001-04-09 | 2005-05-03 | Chiron Corporation | HSA-free formulations of interferon-beta |
| WO2003066585A2 (en) | 2002-02-08 | 2003-08-14 | Alkermes Controlled Therapeutics, Inc. | Polymer-based compositions for sustained release |
| US20040037809A1 (en) | 2002-06-28 | 2004-02-26 | Nastech Pharmaceutical Company Inc. | Compositions and methods for enhanced mucosal delivery of interferon beta |
| TWI272948B (en) * | 2003-05-01 | 2007-02-11 | Ares Trading Sa | HSA-free stabilized interferon liquid formulations |
| AR044302A1 (es) * | 2003-05-13 | 2005-09-07 | Ares Trading Sa | Formulaciones con proteinas liquidas estabilizadas en recipientes farmaceuticos |
| ZA200609412B (en) * | 2004-05-17 | 2008-07-30 | Ares Trading Sa | Hydrogel interferon formulations |
-
2005
- 2005-05-27 JP JP2007513938A patent/JP4988562B2/ja not_active Expired - Lifetime
- 2005-05-27 EA EA200602257A patent/EA010979B1/ru not_active IP Right Cessation
- 2005-05-27 ES ES05752765T patent/ES2418833T3/es not_active Expired - Lifetime
- 2005-05-27 MX MXPA06014078A patent/MXPA06014078A/es active IP Right Grant
- 2005-05-27 AU AU2005249233A patent/AU2005249233B2/en not_active Expired
- 2005-05-27 WO PCT/EP2005/052414 patent/WO2005117949A1/en not_active Ceased
- 2005-05-27 EP EP05752765.7A patent/EP1750751B1/en not_active Expired - Lifetime
- 2005-05-27 US US11/597,987 patent/US7731948B2/en active Active
- 2005-05-27 CN CN2005800257255A patent/CN1993139B/zh not_active Expired - Lifetime
- 2005-05-27 CA CA002567310A patent/CA2567310A1/en not_active Withdrawn
- 2005-05-27 BR BRPI0510526-9A patent/BRPI0510526A/pt not_active IP Right Cessation
- 2005-05-27 UA UAA200612406A patent/UA92146C2/ru unknown
-
2006
- 2006-11-27 IL IL179620A patent/IL179620A/en not_active IP Right Cessation
- 2006-12-19 NO NO20065860A patent/NO20065860L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| AU2005249233B2 (en) | 2010-10-07 |
| CN1993139A (zh) | 2007-07-04 |
| MXPA06014078A (es) | 2007-02-15 |
| EA200602257A1 (ru) | 2007-04-27 |
| JP4988562B2 (ja) | 2012-08-01 |
| EP1750751A1 (en) | 2007-02-14 |
| AU2005249233A1 (en) | 2005-12-15 |
| IL179620A0 (en) | 2007-05-15 |
| CN1993139B (zh) | 2011-02-16 |
| ES2418833T3 (es) | 2013-08-16 |
| JP2008500996A (ja) | 2008-01-17 |
| WO2005117949A1 (en) | 2005-12-15 |
| EA010979B1 (ru) | 2008-12-30 |
| EP1750751B1 (en) | 2013-04-10 |
| HK1102563A1 (en) | 2007-11-30 |
| CA2567310A1 (en) | 2005-12-15 |
| NO20065860L (no) | 2006-12-19 |
| US20070292391A1 (en) | 2007-12-20 |
| BRPI0510526A (pt) | 2007-10-30 |
| US7731948B2 (en) | 2010-06-08 |
| IL179620A (en) | 2013-04-30 |
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