UA93209C2 - Комбинация снотворного агента продолжительного действия эпливансерина и снотворного агента короткого действия золпидема - Google Patents

Комбинация снотворного агента продолжительного действия эпливансерина и снотворного агента короткого действия золпидема

Info

Publication number
UA93209C2
UA93209C2 UAA200803488A UAA200803488A UA93209C2 UA 93209 C2 UA93209 C2 UA 93209C2 UA A200803488 A UAA200803488 A UA A200803488A UA A200803488 A UAA200803488 A UA A200803488A UA 93209 C2 UA93209 C2 UA 93209C2
Authority
UA
Ukraine
Prior art keywords
hypnotic agent
acting hypnotic
combination
short
long
Prior art date
Application number
UAA200803488A
Other languages
English (en)
Ukrainian (uk)
Inventor
Ален Кюин
Мишель Декобер
Доминик Франкон
Анри Сональ
Original Assignee
Санофи-Авентис
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Санофи-Авентис filed Critical Санофи-Авентис
Publication of UA93209C2 publication Critical patent/UA93209C2/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • A61K31/5513—1,4-Benzodiazepines, e.g. diazepam or clozapine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/15—Oximes (>C=N—O—); Hydrazines (>N—N<); Hydrazones (>N—N=) ; Imines (C—N=C)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Изобретение касается комбинации, по меньшей мере, одного снотворного агента короткого действия, который представляет собой золпидем, с по меньшей мере, одним снотворным агентом продолжительного действия, который представляет собой эпливансерин, и его применения для лечения расстройств сна.
UAA200803488A 2005-08-19 2006-07-27 Комбинация снотворного агента продолжительного действия эпливансерина и снотворного агента короткого действия золпидема UA93209C2 (ru)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0508643A FR2889811B1 (fr) 2005-08-19 2005-08-19 Association d'un agent hypnotique a duree d'action longue et d'un agent hypnotique a duree d'action courte, composition pharmaceutique la contenant et son application en therapeutique.

Publications (1)

Publication Number Publication Date
UA93209C2 true UA93209C2 (ru) 2011-01-25

Family

ID=36273351

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA200803488A UA93209C2 (ru) 2005-08-19 2006-07-27 Комбинация снотворного агента продолжительного действия эпливансерина и снотворного агента короткого действия золпидема

Country Status (25)

Country Link
US (2) US20080181943A1 (ru)
EP (1) EP1919473B1 (ru)
JP (1) JP5215851B2 (ru)
KR (1) KR20080039909A (ru)
CN (1) CN101267819B (ru)
AR (1) AR055123A1 (ru)
AU (1) AU2006281334B2 (ru)
BR (1) BRPI0614792A2 (ru)
CA (1) CA2618212C (ru)
CR (1) CR9695A (ru)
EA (1) EA014294B1 (ru)
EC (1) ECSP088131A (ru)
FR (1) FR2889811B1 (ru)
HN (1) HN2008000278A (ru)
IL (1) IL188823A0 (ru)
MA (1) MA29766B1 (ru)
MX (1) MX2008002275A (ru)
NO (1) NO20081250L (ru)
NZ (1) NZ565880A (ru)
SG (1) SG165316A1 (ru)
TN (1) TNSN08027A1 (ru)
TW (1) TW200738238A (ru)
UA (1) UA93209C2 (ru)
WO (1) WO2007020337A1 (ru)
ZA (1) ZA200800968B (ru)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW200626137A (en) * 2004-12-13 2006-08-01 Takeda Pharmaceuticals Co Preventive or therapeutic agent for sleep disorder
WO2009084023A2 (en) * 2007-10-19 2009-07-09 Glenmark Generics Limited Amorphous ramelteon and process for the preparation thereof
JP2011507835A (ja) 2007-12-21 2011-03-10 アンドレイ・アレクサンドロビッチ・イワシェンコ α−アドレナリン受容体、ドーパミン、ヒスタミン、イミダゾリン及びセロトニン受容体のリガンド並びにその使用
US20120108669A1 (en) * 2008-11-13 2012-05-03 Sanofi-Aventis Method of treating sleep disorders using eplivanserin
FR2938534B1 (fr) 2008-11-14 2012-10-26 Sanofi Aventis Procede de preparation de l'hemifumarate d'eplivanserine
US20100196286A1 (en) * 2008-12-01 2010-08-05 Armer Thomas A Inhalation delivery methods and devices
US8555875B2 (en) 2008-12-23 2013-10-15 Map Pharmaceuticals, Inc. Inhalation devices and related methods for administration of sedative hypnotic compounds
SI2395840T1 (sl) 2009-02-13 2020-08-31 Romark Laboratories, L.C. Farmacevtske formulacije nitazoksanida z nadzorovanim sproščanjem
EP2255807A1 (en) * 2009-05-26 2010-12-01 Sanofi-Aventis Method of treating sleep disorders using the combination of eplivanserin and zolpidem
EP2255726A1 (en) * 2009-05-26 2010-12-01 Sanofi-Aventis Spectral profile of SWS enhancing drugs
WO2012109695A1 (en) * 2011-02-16 2012-08-23 Casal Y Galzov Ramon Ernesto Drug compositions for the treatment of insomnia
WO2012170883A1 (en) 2011-06-09 2012-12-13 Discovery Pharma Consulting, Llc Antihistamines combined with dietary supplements for improved health
CN102579383A (zh) * 2012-04-09 2012-07-18 南京正科制药有限公司 右佐匹克隆缓释片
CA2934595C (en) * 2014-02-06 2022-06-21 Sequential Medicine Limited Composition and method for aiding sleep
RU2697836C2 (ru) 2015-06-26 2019-08-21 Кореа Юнайтед Фарм. Инк. Комбинированный препарат мозаприда и рабепразола
CN105596313B (zh) * 2016-02-17 2018-06-29 新乡医学院第一附属医院 一种具有反向药理功能的用于治疗失眠的胶囊制剂
CN105997958B (zh) * 2016-07-12 2019-03-26 中国人民解放军白求恩医务士官学校 一种口腔外用制剂及其制备方法
SG11201903829PA (en) * 2016-10-31 2019-05-30 Neurim Pharma 1991 Melatonin mini-tablets and method of manufacturing the same
EP3567030B1 (en) * 2016-12-30 2022-02-09 Medshine Discovery Inc. Quinazoline compound for egfr inhibition
KR102874891B1 (ko) 2018-01-30 2025-10-21 애프니메드, 인코포레이티드 (델라웨어) 수면 무호흡증을 치료하기 위한 방법 및 조성물
JP2022514194A (ja) 2018-11-21 2022-02-10 セルテゴ セラピューティクス インコーポレイテッド 自殺のリスクを低減し、うつ病を迅速に軽減するためのガボキサドール
CN118557736A (zh) 2019-02-08 2024-08-30 布里格姆妇女医院 用于治疗睡眠呼吸暂停的方法和组合物
MX2022014599A (es) 2020-05-20 2022-12-16 Certego Therapeutics Inc Gaboxadol deuterado en anillo y su uso para el tratamiento de trastornos psiquiatricos.
FR3116439B1 (fr) * 2020-11-26 2023-08-04 Laboratoire Dielen Comprimé pelliculé contenant au moins un principe actif, adapté à l’administration par voie orale dudit au moins un principe actif chez des sujets humains
CN115919806A (zh) * 2022-12-22 2023-04-07 南京乐韬生物科技有限公司 一种gaba缓释胶囊的制备方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1100508B8 (en) * 1998-06-09 2004-01-07 Takeda Chemical Industries, Ltd. Pharmaceutical combination comprising a tricyclic compound and at least one of zolpidem, zopiclone and brotizolam for treating or preventing sleep disorders
JP3509637B2 (ja) * 1998-06-09 2004-03-22 武田薬品工業株式会社 睡眠障害予防治療剤
EP1005863A1 (en) * 1998-12-04 2000-06-07 Synthelabo Controlled-release dosage forms comprising a short acting hypnotic or a salt thereof
PL1691811T3 (pl) * 2003-12-11 2014-12-31 Sunovion Pharmaceuticals Inc Skojarzenie leku uspokajającego i modulatora neuroprzekaźnikowego oraz sposoby poprawy jakości snu i leczenia depresji
EP1696959A2 (en) * 2003-12-24 2006-09-06 Sepracor, Inc. Melatonin combination therapy for improving sleep quality
TW200626137A (en) * 2004-12-13 2006-08-01 Takeda Pharmaceuticals Co Preventive or therapeutic agent for sleep disorder
JP2009500421A (ja) * 2005-07-06 2009-01-08 セプラコア インコーポレーテッド エスゾピクロン及び抗うつ薬の組み合わせ
ES2336142T3 (es) * 2005-08-19 2010-04-08 Aventis Pharmaceuticals Inc. Combinacion de un agente hipnotico y un compuesto sustituido, con bis arilo y heteroarilo y aplicacion terapeutica del mismo.
KR20080034475A (ko) * 2005-08-19 2008-04-21 아벤티스 파마슈티칼스 인크. 수면제 및ｒ(＋)-알파-(2,3-디메톡시-페닐)-1-[2-(4-플루오로페닐)에틸]-4-피페리딘메탄올의 복합물 및 이의 치료학적 용도

Also Published As

Publication number Publication date
WO2007020337A1 (fr) 2007-02-22
JP2009504713A (ja) 2009-02-05
ECSP088131A (es) 2008-02-20
US20100291204A1 (en) 2010-11-18
EP1919473B1 (fr) 2012-12-05
HK1124541A1 (en) 2009-07-17
CA2618212C (fr) 2014-03-25
TNSN08027A1 (en) 2009-07-14
MA29766B1 (fr) 2008-09-01
IL188823A0 (en) 2008-12-29
EP1919473A1 (fr) 2008-05-14
ZA200800968B (en) 2009-04-29
SG165316A1 (en) 2010-10-28
AR055123A1 (es) 2007-08-08
BRPI0614792A2 (pt) 2011-04-12
JP5215851B2 (ja) 2013-06-19
AU2006281334A1 (en) 2007-02-22
NO20081250L (no) 2008-05-13
KR20080039909A (ko) 2008-05-07
NZ565880A (en) 2011-07-29
TW200738238A (en) 2007-10-16
CR9695A (es) 2008-02-20
US20080181943A1 (en) 2008-07-31
EA200800618A1 (ru) 2008-06-30
CN101267819B (zh) 2012-05-30
CN101267819A (zh) 2008-09-17
FR2889811A1 (fr) 2007-02-23
MX2008002275A (es) 2008-03-27
CA2618212A1 (fr) 2007-02-22
EA014294B1 (ru) 2010-10-29
AU2006281334B2 (en) 2012-10-18
HN2008000278A (es) 2011-03-30
FR2889811B1 (fr) 2009-10-09

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