UA94036C2 - Bendamustine pharmaceutical compositions for lyophilisation - Google Patents
Bendamustine pharmaceutical compositions for lyophilisationInfo
- Publication number
- UA94036C2 UA94036C2 UAA200709242A UAA200709242A UA94036C2 UA 94036 C2 UA94036 C2 UA 94036C2 UA A200709242 A UAA200709242 A UA A200709242A UA A200709242 A UAA200709242 A UA A200709242A UA 94036 C2 UA94036 C2 UA 94036C2
- Authority
- UA
- Ukraine
- Prior art keywords
- lyophilisation
- bendamustine
- pharmaceutical compositions
- bendamustine pharmaceutical
- present
- Prior art date
Links
- YTKUWDBFDASYHO-UHFFFAOYSA-N bendamustine Chemical compound ClCCN(CCCl)C1=CC=C2N(C)C(CCCC(O)=O)=NC2=C1 YTKUWDBFDASYHO-UHFFFAOYSA-N 0.000 title abstract 4
- 229960002707 bendamustine Drugs 0.000 title abstract 4
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 3
- 238000004108 freeze drying Methods 0.000 title 1
- 201000010099 disease Diseases 0.000 abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 1
- 230000001613 neoplastic effect Effects 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
The present invention provides pharmaceutical formulations of lyophilized bendamustine suitable for pharmaceutical use. The present invention further provides methods of producing lyophilized bendamustine. The pharmaceutical formulations can be used for any disease that is sensitive to treatment with bendamustine, such as neoplastic diseases.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US64435405P | 2005-01-14 | 2005-01-14 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UA94036C2 true UA94036C2 (en) | 2011-04-11 |
Family
ID=39055518
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UAA200709242A UA94036C2 (en) | 2005-01-14 | 2006-01-13 | Bendamustine pharmaceutical compositions for lyophilisation |
Country Status (3)
| Country | Link |
|---|---|
| CN (1) | CN101119708B (en) |
| UA (1) | UA94036C2 (en) |
| ZA (1) | ZA200705793B (en) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AR072777A1 (en) * | 2008-03-26 | 2010-09-22 | Cephalon Inc | SOLID FORMS OF BENDAMUSTINE CHLORHYDRATE |
| WO2010036702A1 (en) * | 2008-09-25 | 2010-04-01 | Cephalon, Inc. | Liquid formulations of bendamustine |
| UA102120C2 (en) * | 2008-12-03 | 2013-06-10 | Астеллас Дойчленд Гмбх | Oral dosage forms of bendamustine |
| CA2753641C (en) * | 2009-02-25 | 2014-09-16 | Supratek Pharma, Inc. | Bendamustine cyclopolysaccharide compositions |
| CN101836962B (en) * | 2009-03-20 | 2013-02-20 | 北京本草天源药物研究院 | Method for preparing bendamustine hydrochloride freeze-dried powder injection |
| CN101606934B (en) * | 2009-07-27 | 2011-09-28 | 江苏奥赛康药业有限公司 | Bendamustine hydrochloride composition |
| CN101912369B (en) * | 2010-07-29 | 2012-11-14 | 深圳万乐药业有限公司 | Method for preparing bendamustine hydrochloride freeze-dried preparation |
| CN102375044B (en) * | 2010-08-18 | 2015-04-08 | 重庆华邦胜凯制药有限公司 | Method for analyzing related substance from hydrochloric acid bendamustine intermediate Z6 |
| CN103351346A (en) * | 2013-07-29 | 2013-10-16 | 东南大学 | Preparation method of impurity HP1 in bendamustine hydrochloride |
| CN103989641A (en) * | 2014-05-29 | 2014-08-20 | 四川汇宇制药有限公司 | Preparation method of bendamustine hydrochloride composition for injection |
| CN105272920B (en) * | 2014-07-17 | 2020-01-24 | 江苏先声药业有限公司 | Bendamustine hydrochloride mannitol ester and preparation method and application thereof |
| CN108078931B (en) * | 2017-12-12 | 2019-02-01 | 健进制药有限公司 | A kind of bendamustine hydrochloride freeze-dried powder needle and preparation method thereof |
| CN108324691B (en) * | 2018-04-11 | 2019-03-08 | 健进制药有限公司 | A kind of injection Carmustine lyophilized preparation and preparation method thereof |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6261537B1 (en) * | 1996-10-28 | 2001-07-17 | Nycomed Imaging As | Diagnostic/therapeutic agents having microbubbles coupled to one or more vectors |
-
2006
- 2006-01-13 CN CN200680002440.4A patent/CN101119708B/en not_active Expired - Lifetime
- 2006-01-13 UA UAA200709242A patent/UA94036C2/en unknown
-
2007
- 2007-07-13 ZA ZA200705793A patent/ZA200705793B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ZA200705793B (en) | 2008-09-25 |
| CN101119708A (en) | 2008-02-06 |
| CN101119708B (en) | 2014-12-24 |
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