UA96257C2 - Стабілізована фармацевтична композиція лейкотриєн-b4 (ltb4) агента - Google Patents
Стабілізована фармацевтична композиція лейкотриєн-b4 (ltb4) агентаInfo
- Publication number
- UA96257C2 UA96257C2 UAA200704260A UAA200704260A UA96257C2 UA 96257 C2 UA96257 C2 UA 96257C2 UA A200704260 A UAA200704260 A UA A200704260A UA A200704260 A UAA200704260 A UA A200704260A UA 96257 C2 UA96257 C2 UA 96257C2
- Authority
- UA
- Ukraine
- Prior art keywords
- ltb4
- pharmaceutical formulation
- leukotriene
- stabilized
- agent pharmaceutical
- Prior art date
Links
- VNYSSYRCGWBHLG-AMOLWHMGSA-N leukotriene B4 Chemical compound CCCCC\C=C/C[C@@H](O)\C=C\C=C\C=C/[C@@H](O)CCCC(O)=O VNYSSYRCGWBHLG-AMOLWHMGSA-N 0.000 title abstract 3
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 238000009472 formulation Methods 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
- A61K31/202—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/2853—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers, poly(lactide-co-glycolide)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2886—Dragees; Coated pills or tablets, e.g. with film or compression coating having two or more different drug-free coatings; Tablets of the type inert core-drug layer-inactive layer
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Dermatology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Inorganic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Даний винахід стосується нової фармацевтичної композиції, що містить LTB4 агент при лужній рН, ефективній для стабілізації LTB4 агента, та являє собою композицію з підвищеним терміном придатності. Композиція за даним винаходом має підвищений термін придатності, переважно щонайменше 24 місяці.
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US61096204P | 2004-09-20 | 2004-09-20 | |
| US63500904P | 2004-12-13 | 2004-12-13 | |
| US63548204P | 2004-12-14 | 2004-12-14 | |
| PCT/IB2005/002781 WO2006032977A2 (en) | 2004-09-20 | 2005-09-20 | Stabilized leukotriene b4 (ltb4) agent pharmaceutical |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UA96257C2 true UA96257C2 (uk) | 2011-10-25 |
Family
ID=35902513
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UAA200704260A UA96257C2 (uk) | 2004-09-20 | 2005-09-20 | Стабілізована фармацевтична композиція лейкотриєн-b4 (ltb4) агента |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US8664271B2 (uk) |
| EP (1) | EP1796730B1 (uk) |
| JP (1) | JP4767256B2 (uk) |
| KR (1) | KR101109735B1 (uk) |
| CN (1) | CN101039698B (uk) |
| AT (1) | ATE474603T1 (uk) |
| AU (1) | AU2005286161B2 (uk) |
| BR (1) | BRPI0516957A (uk) |
| CA (1) | CA2581156C (uk) |
| CY (1) | CY1110841T1 (uk) |
| DE (1) | DE602005022462D1 (uk) |
| DK (1) | DK1796730T3 (uk) |
| EA (1) | EA012982B1 (uk) |
| ES (1) | ES2349410T3 (uk) |
| NO (1) | NO20071977L (uk) |
| NZ (1) | NZ553982A (uk) |
| PL (1) | PL1796730T3 (uk) |
| PT (1) | PT1796730E (uk) |
| SI (1) | SI1796730T1 (uk) |
| TW (1) | TWI361078B (uk) |
| UA (1) | UA96257C2 (uk) |
| WO (1) | WO2006032977A2 (uk) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1840114A1 (en) * | 2006-03-30 | 2007-10-03 | LTB4 Sweden AB | Crystalline Leukotriene B4 |
| CN102435443B (zh) * | 2011-09-08 | 2014-04-02 | 中国汽车技术研究中心 | 汽车催化器快速老化数据采集系统 |
| JP6483593B2 (ja) * | 2015-03-06 | 2019-03-13 | アークレイ株式会社 | 血液検査装置および血液検査方法 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0179959A1 (en) * | 1982-04-20 | 1986-05-07 | Merck Frosst Canada Inc. | Conjugates of leukotrienes with proteins |
| US4568559A (en) * | 1984-02-06 | 1986-02-04 | Biotek, Inc. | Composite core coated microparticles and process of preparing same |
| GB2189698A (en) * | 1986-04-30 | 1987-11-04 | Haessle Ab | Coated omeprazole tablets |
| US4876505A (en) * | 1988-05-27 | 1989-10-24 | Westinghouse Electric Corp. | Apparatus and method for monitoring steam turbine shroud clearance |
| US20040132820A1 (en) | 1996-02-15 | 2004-07-08 | Jean Gosselin | Agents with leukotriene B4-like antiviral (DNA) and anti-neoplastic activities |
| US5789441A (en) * | 1996-02-15 | 1998-08-04 | Virocell Inc. | Leukotriene B4 as an antiviral and anti-neoplastic agent |
| US5780055A (en) * | 1996-09-06 | 1998-07-14 | University Of Maryland, Baltimore | Cushioning beads and tablet comprising the same capable of forming a suspension |
| US5909734A (en) * | 1996-12-03 | 1999-06-08 | Regents Of The University Of Michigan | Administration of products of the 5-lipoxygenase metabolic pathway to enhance antimicrobial defense |
| CA2452008C (en) * | 2001-07-05 | 2012-03-06 | Virocell Inc. | Ltb4 as vaccine adjuvant |
| WO2003105823A1 (en) * | 2002-06-14 | 2003-12-24 | Alcon, Inc. | Use of hydroxyeicosatetraenoic acid compounds to treat dry mouth |
-
2005
- 2005-09-20 AT AT05786891T patent/ATE474603T1/de active
- 2005-09-20 CN CN2005800317006A patent/CN101039698B/zh not_active Expired - Fee Related
- 2005-09-20 PT PT05786891T patent/PT1796730E/pt unknown
- 2005-09-20 BR BRPI0516957-7A patent/BRPI0516957A/pt not_active IP Right Cessation
- 2005-09-20 JP JP2007531861A patent/JP4767256B2/ja not_active Expired - Fee Related
- 2005-09-20 CA CA2581156A patent/CA2581156C/en not_active Expired - Fee Related
- 2005-09-20 DK DK05786891.1T patent/DK1796730T3/da active
- 2005-09-20 AU AU2005286161A patent/AU2005286161B2/en not_active Ceased
- 2005-09-20 EA EA200700676A patent/EA012982B1/ru not_active IP Right Cessation
- 2005-09-20 TW TW094132426A patent/TWI361078B/zh active
- 2005-09-20 EP EP05786891A patent/EP1796730B1/en not_active Expired - Lifetime
- 2005-09-20 UA UAA200704260A patent/UA96257C2/uk unknown
- 2005-09-20 WO PCT/IB2005/002781 patent/WO2006032977A2/en not_active Ceased
- 2005-09-20 KR KR1020077009102A patent/KR101109735B1/ko not_active Expired - Fee Related
- 2005-09-20 US US11/231,359 patent/US8664271B2/en not_active Expired - Fee Related
- 2005-09-20 DE DE602005022462T patent/DE602005022462D1/de not_active Expired - Lifetime
- 2005-09-20 SI SI200531135T patent/SI1796730T1/sl unknown
- 2005-09-20 NZ NZ553982A patent/NZ553982A/en not_active IP Right Cessation
- 2005-09-20 ES ES05786891T patent/ES2349410T3/es not_active Expired - Lifetime
- 2005-09-20 PL PL05786891T patent/PL1796730T3/pl unknown
-
2007
- 2007-04-18 NO NO20071977A patent/NO20071977L/no not_active Application Discontinuation
-
2010
- 2010-10-20 CY CY20101100940T patent/CY1110841T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE602005022462D1 (de) | 2010-09-02 |
| KR20070085277A (ko) | 2007-08-27 |
| EA200700676A1 (ru) | 2007-10-26 |
| PL1796730T3 (pl) | 2010-12-31 |
| BRPI0516957A (pt) | 2008-09-30 |
| CN101039698A (zh) | 2007-09-19 |
| TW200626175A (en) | 2006-08-01 |
| TWI361078B (en) | 2012-04-01 |
| AU2005286161B2 (en) | 2010-09-09 |
| US20060063837A1 (en) | 2006-03-23 |
| EP1796730A2 (en) | 2007-06-20 |
| EA012982B1 (ru) | 2010-02-26 |
| NO20071977L (no) | 2007-04-18 |
| ES2349410T3 (es) | 2011-01-03 |
| JP4767256B2 (ja) | 2011-09-07 |
| CY1110841T1 (el) | 2015-06-10 |
| JP2008513431A (ja) | 2008-05-01 |
| CN101039698B (zh) | 2011-11-09 |
| PT1796730E (pt) | 2010-10-26 |
| ATE474603T1 (de) | 2010-08-15 |
| WO2006032977A2 (en) | 2006-03-30 |
| WO2006032977A3 (en) | 2006-07-13 |
| CA2581156C (en) | 2011-07-12 |
| NZ553982A (en) | 2009-09-25 |
| HK1103652A1 (en) | 2007-12-28 |
| US8664271B2 (en) | 2014-03-04 |
| CA2581156A1 (en) | 2006-03-30 |
| SI1796730T1 (sl) | 2010-12-31 |
| DK1796730T3 (da) | 2010-11-01 |
| KR101109735B1 (ko) | 2012-02-17 |
| AU2005286161A1 (en) | 2006-03-30 |
| EP1796730B1 (en) | 2010-07-21 |
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