UA96265C2 - Composition and method for inhibition of the jak pathway - Google Patents

Composition and method for inhibition of the jak pathway

Info

Publication number
UA96265C2
UA96265C2 UAA200714921A UAA200714921A UA96265C2 UA 96265 C2 UA96265 C2 UA 96265C2 UA A200714921 A UAA200714921 A UA A200714921A UA A200714921 A UAA200714921 A UA A200714921A UA 96265 C2 UA96265 C2 UA 96265C2
Authority
UA
Ukraine
Prior art keywords
inhibition
composition
jak pathway
jak
pathway
Prior art date
Application number
UAA200714921A
Other languages
Russian (ru)
Ukrainian (uk)
Inventor
Гуи Ли
Самбаиах Тота
Дейвид Керролл
Анкуш Аргейд
Кин Тсо
Арвиндер Срен
Джеффри Клоф
Хольгер Кеим
Сомасекхар БХАМИДИПАТИ
Ванесса Тейлор
Робин КУПЕР
Раджиндер Сингх
Брайан Вонг
Original Assignee
Райджел Фармасьютикалс, Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Райджел Фармасьютикалс, Инк. filed Critical Райджел Фармасьютикалс, Инк.
Publication of UA96265C2 publication Critical patent/UA96265C2/en

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

The invention encompasses compounds having formula (I-V) and the compositions and methods using these compounds in the treatment of conditions in which modulation of the JAK pathway or inhibition of JAK kinases, particularly JAK3, may be therapeutically useful.
UAA200714921A 2005-06-08 2006-06-08 Composition and method for inhibition of the jak pathway UA96265C2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US68903205P 2005-06-08 2005-06-08

Publications (1)

Publication Number Publication Date
UA96265C2 true UA96265C2 (en) 2011-10-25

Family

ID=40014879

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA200714921A UA96265C2 (en) 2005-06-08 2006-06-08 Composition and method for inhibition of the jak pathway

Country Status (3)

Country Link
CN (1) CN101282945A (en)
UA (1) UA96265C2 (en)
ZA (2) ZA200710206B (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8338439B2 (en) * 2008-06-27 2012-12-25 Celgene Avilomics Research, Inc. 2,4-disubstituted pyrimidines useful as kinase inhibitors
WO2010072155A1 (en) * 2008-12-26 2010-07-01 复旦大学 Pyrimidine derivative, preparation method and use thereof
JP5658685B2 (en) * 2009-01-14 2015-01-28 ライジェル ファーマシューティカルズ， インコーポレイテッド 2,4-pyrimidinediamine compounds for the treatment of inflammatory disorders
AU2011282742B2 (en) * 2010-07-28 2015-08-27 Rigel Pharmaceuticals, Inc. Compositions and methods for inhibition of the JAK pathway
CN103159749A (en) * 2011-12-13 2013-06-19 南京友杰医药科技有限公司 Synthesis method for antidepressant drug vilazodone
CN105683167B (en) * 2013-10-16 2018-10-23 富士胶片株式会社 Salt of nitrogen-containing heterocyclic compound or its crystal, pharmaceutical composition and FLT3 inhibitor
CN105924389A (en) * 2015-12-18 2016-09-07 重庆两江药物研发中心有限公司 Preparation method of regorafenib intermediate
CN110256465B (en) * 2019-07-13 2021-08-13 南方医科大学 A kind of 2,4-diaminopyrimidine containing dihydropyranothiazole and application thereof
CN117402178B (en) * 2023-12-15 2024-03-08 英矽智能科技(上海)有限公司 Pyrimidine compounds as JAK inhibitors and PHD inhibitors
CN117756822B (en) * 2023-12-20 2025-04-18 英矽智能科技(上海)有限公司 Pyrimidine amino compounds as JAK inhibitors and PHD inhibitors
CN120647626B (en) * 2025-06-09 2026-02-27 江西省肿瘤医院(江西省第二人民医院、江西省癌症中心) A 4-aminopyrimidine compound targeting EGFR and AXL, its preparation method and application

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0004888D0 (en) * 2000-03-01 2000-04-19 Astrazeneca Uk Ltd Chemical compounds

Also Published As

Publication number Publication date
CN101282945A (en) 2008-10-08
ZA200809949B (en) 2010-08-25
ZA200710206B (en) 2009-12-30

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