UA97092C2 - T-клеточные эпитопы с раково-эмбрионального антиген-незрелого рецепторного белка ламинина и их медицинское применение - Google Patents

T-клеточные эпитопы с раково-эмбрионального антиген-незрелого рецепторного белка ламинина и их медицинское применение

Info

Publication number
UA97092C2
UA97092C2 UAA200712736A UAA200712736A UA97092C2 UA 97092 C2 UA97092 C2 UA 97092C2 UA A200712736 A UAA200712736 A UA A200712736A UA A200712736 A UAA200712736 A UA A200712736A UA 97092 C2 UA97092 C2 UA 97092C2
Authority
UA
Ukraine
Prior art keywords
laminin receptor
oncofetal antigen
receptor protein
cell epitopes
medical uses
Prior art date
Application number
UAA200712736A
Other languages
English (en)
Ukrainian (uk)
Inventor
Маттиас Цайс
Original Assignee
Имматикс Биотекнолоджис Гмбх
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Имматикс Биотекнолоджис Гмбх filed Critical Имматикс Биотекнолоджис Гмбх
Publication of UA97092C2 publication Critical patent/UA97092C2/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4748—Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Данное изобретение относится к методам иммунотерапии, а также к молекулам и клеткам, которые применяются в иммунотерапевтических методах, к новой пептидной последовательности, полученной из молекул HLA I или II класса раково-эмбрионального антиген-незрелого рецептора ламинина (OFA/ilr) человека, который может использоваться в вакцинных или других фармацевтических композициях для стимулирования противоопухолевых иммунных реакций.
UAA200712736A 2005-04-26 2006-04-26 T-клеточные эпитопы с раково-эмбрионального антиген-незрелого рецепторного белка ламинина и их медицинское применение UA97092C2 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP05009095A EP1717245B1 (en) 2005-04-26 2005-04-26 T-cell epitopes from the oncofetal antigen-immature laminin receptor protein and medical uses thereof
PCT/EP2006/003888 WO2006114307A1 (en) 2005-04-26 2006-04-26 T-cell epitopes from the oncofetal antigen-immature laminin receptor protein and medical uses thereof

Publications (1)

Publication Number Publication Date
UA97092C2 true UA97092C2 (ru) 2012-01-10

Family

ID=34935739

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA200712736A UA97092C2 (ru) 2005-04-26 2006-04-26 T-клеточные эпитопы с раково-эмбрионального антиген-незрелого рецепторного белка ламинина и их медицинское применение

Country Status (14)

Country Link
US (1) US7968097B2 (ru)
EP (2) EP1717245B1 (ru)
JP (1) JP4870751B2 (ru)
CN (1) CN101166759B (ru)
AT (1) ATE512160T1 (ru)
AU (1) AU2006239505B2 (ru)
BR (1) BRPI0610841A2 (ru)
CA (1) CA2606088C (ru)
EA (1) EA013598B1 (ru)
ES (1) ES2367643T3 (ru)
NO (1) NO20076041L (ru)
NZ (1) NZ563432A (ru)
UA (1) UA97092C2 (ru)
WO (1) WO2006114307A1 (ru)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2003258081A1 (en) * 2002-08-02 2004-02-23 South Alabama Medical Sciences Foundation Cancer vaccines containing epitopes of oncofetal antigen
US20090004213A1 (en) 2007-03-26 2009-01-01 Immatics Biotechnologies Gmbh Combination therapy using active immunotherapy
BRPI0814140A2 (pt) * 2007-07-27 2017-03-28 Immatics Biotechnologies Gmbh composição de peptídeos associados a tumor e vacina anticâncer relacionada
DE602008000891D1 (de) 2008-04-30 2010-05-12 Immatics Biotechnologies Gmbh Neuartige Formulierungen von Tumor-assoziierten Peptiden, welche an menschliche Leukozytenantigene der Klasse I oder II für Impfungen binden
EP2411415A1 (en) * 2009-03-26 2012-02-01 Quantum Immunologics, Inc. Oncofetal antigen/immature laminin receptor antibodies for diagnostic and clinical applications
WO2011006084A2 (en) * 2009-07-09 2011-01-13 South Alabama Medical Science Vaccines with oncofetal antigen/ilrp-loaded autologous dendritic cells and uses thereof
EP2471901A4 (en) * 2009-08-25 2013-06-26 Takara Bio Inc PROCESS FOR PRODUCING T-CELL POPULATION IN THE PRESENCE OF RETINOIC ACID
EP2330122A1 (en) * 2009-12-02 2011-06-08 Asklepios Kliniken Hamburg Gmbh OFA/iLRP derived modified peptide
NL2014935B1 (en) 2015-06-08 2017-02-03 Applied Immune Tech Ltd T cell receptor like antibodies having fine specificity.
DE102016123893A1 (de) 2016-12-08 2018-06-14 Immatics Biotechnologies Gmbh T-Zellrezeptoren mit verbesserter Bindung
EP4317432A3 (en) 2016-12-08 2024-04-17 Immatics Biotechnologies GmbH T cell receptors with improved pairing
EP3609530A1 (en) * 2017-04-10 2020-02-19 Immatics Biotechnologies GmbH Peptides and combination thereof for use in the immunotherapy against cancers
WO2018224166A1 (en) * 2017-06-09 2018-12-13 Biontech Rna Pharmaceuticals Gmbh Methods for predicting the usefulness of disease specific amino acid modifications for immunotherapy
JP2021526365A (ja) * 2018-05-18 2021-10-07 チルドレンズ ナショナル メディカル センターＣｈｉｌｄｒｅｎ’Ｓ Ｎａｔｉｏｎａｌ Ｍｅｄｉｃａｌ Ｃｅｎｔｅｒ 改善された標的化ｔ細胞療法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ290089A (en) 1994-07-27 1999-05-28 Queensland Inst Med Res Recombinant polyepitope cytotoxic t lymphocyte (ctl) vaccines
CA2243235C (en) 1996-01-17 2010-08-10 Imperial College Innovations Limited Immunotherapy using cytotoxic t lymphocytes (ctl)
US20040236091A1 (en) 2001-03-28 2004-11-25 Chicz Roman M. Translational profiling
AU2003258081A1 (en) 2002-08-02 2004-02-23 South Alabama Medical Sciences Foundation Cancer vaccines containing epitopes of oncofetal antigen
CA2500687A1 (en) 2002-10-02 2004-04-15 Genentech, Inc. Compositions and methods for the diagnosis and treatment of tumor
US20070166318A1 (en) * 2003-05-30 2007-07-19 Macina Roberto A Compositions, splice variants and methods relating to ovarian specific nucleic acids and proteins
US20080206270A1 (en) * 2004-07-08 2008-08-28 Minev Boris R Enhancing Class I Antigen Presentation With Synthetic Sequences

Also Published As

Publication number Publication date
EP1874810A1 (en) 2008-01-09
CN101166759B (zh) 2012-09-05
CA2606088C (en) 2015-05-26
NO20076041L (no) 2007-11-23
AU2006239505B2 (en) 2012-05-10
AU2006239505A1 (en) 2006-11-02
BRPI0610841A2 (pt) 2010-07-27
US20090041794A1 (en) 2009-02-12
US7968097B2 (en) 2011-06-28
ATE512160T1 (de) 2011-06-15
JP4870751B2 (ja) 2012-02-08
WO2006114307A1 (en) 2006-11-02
CN101166759A (zh) 2008-04-23
EA200702202A1 (ru) 2008-04-28
EA013598B1 (ru) 2010-06-30
ES2367643T3 (es) 2011-11-07
JP2008538901A (ja) 2008-11-13
EP1717245B1 (en) 2011-06-08
NZ563432A (en) 2010-11-26
EP1717245A1 (en) 2006-11-02
CA2606088A1 (en) 2006-11-02

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