UA97237C2 - Производные таксола с противоопухолевой активностью - Google Patents

Производные таксола с противоопухолевой активностью

Info

Publication number
UA97237C2
UA97237C2 UAA200810233A UAA200810233A UA97237C2 UA 97237 C2 UA97237 C2 UA 97237C2 UA A200810233 A UAA200810233 A UA A200810233A UA A200810233 A UAA200810233 A UA A200810233A UA 97237 C2 UA97237 C2 UA 97237C2
Authority
UA
Ukraine
Prior art keywords
heading
normal
antitumor activity
taxol derivatives
taxol
Prior art date
Application number
UAA200810233A
Other languages
English (en)
Ukrainian (uk)
Inventor
Пиаоянг Сун
Ксиншенг Лей
Кайхонг Юан
Original Assignee
Шанхай Хенгруй Фармасьютикал Ко. Лтд.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Шанхай Хенгруй Фармасьютикал Ко. Лтд. filed Critical Шанхай Хенгруй Фармасьютикал Ко. Лтд.
Publication of UA97237C2 publication Critical patent/UA97237C2/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/08—Bridged systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

Описываются производные таксола или их соли, которые имеют следующую формулу:,где, R, R, Z, Z, Zи Zявляются такими, как определено в описании.Также описываются способы их получения и их применения в качестве противоопухолевого агента.
UAA200810233A 2006-01-10 2007-01-05 Производные таксола с противоопухолевой активностью UA97237C2 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CNB2006100012057A CN100516067C (zh) 2006-01-10 2006-01-10 具有抗肿瘤活性的紫杉酚衍生物
PCT/CN2007/000022 WO2007079666A1 (en) 2006-01-10 2007-01-05 Taxol derivatives with antitumor activity

Publications (1)

Publication Number Publication Date
UA97237C2 true UA97237C2 (ru) 2012-01-25

Family

ID=38255980

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA200810233A UA97237C2 (ru) 2006-01-10 2007-01-05 Производные таксола с противоопухолевой активностью

Country Status (13)

Country Link
US (1) US8362240B2 (ru)
EP (1) EP1980562A4 (ru)
JP (1) JP2009522380A (ru)
KR (1) KR20080094025A (ru)
CN (1) CN100516067C (ru)
AU (1) AU2007204520A1 (ru)
BR (1) BRPI0706384A2 (ru)
CA (1) CA2636211A1 (ru)
MX (1) MX2008008905A (ru)
RU (1) RU2419622C2 (ru)
UA (1) UA97237C2 (ru)
WO (1) WO2007079666A1 (ru)
ZA (1) ZA200805910B (ru)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI4426434T3 (fi) 2021-11-02 2025-11-24 Flare Therapeutics Inc Pparg:n käänteisagonisteja ja niiden käyttöjä

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2059631C1 (ru) * 1991-11-29 1996-05-10 Дзе Юниверсити оф Канзас Производные таксола и фармацевтическая композиция, обладающая противоопухолевой активностью
FR2698871B1 (fr) * 1992-12-09 1995-02-24 Rhone Poulenc Rorer Sa Nouveau taxoïdes, leur préparation et les compositions pharmaceutiques qui les contiennent.
WO1994020088A1 (en) 1993-03-05 1994-09-15 Florida State University C9 taxane derivatives and pharmaceutical compositions containing them
US5475011A (en) * 1993-03-26 1995-12-12 The Research Foundation Of State University Of New York Anti-tumor compounds, pharmaceutical compositions, methods for preparation thereof and for treatment
EP0826688B1 (en) * 1995-04-28 2001-09-05 Daiichi Pharmaceutical Co., Ltd. Pentacyclic compounds
TW527183B (en) 1996-06-06 2003-04-11 Daiichi Seiyaku Co Drug complex
KR100706566B1 (ko) * 1999-10-15 2007-04-13 다이이찌 세이야꾸 가부시기가이샤 5환성 탁산 화합물
US6677456B2 (en) * 1999-10-15 2004-01-13 Daiichi Pharmaceutical Co., Ltd. Pentacyclic taxan compound
EP1299374B1 (en) * 2000-06-22 2006-12-27 Pharmos Corporation Novel non-psychotropic cannabinoids
WO2004064728A2 (en) * 2003-01-16 2004-08-05 Paratek Pharmaceuticals, Inc. Use of specific tetracycline compounds in therapy

Also Published As

Publication number Publication date
BRPI0706384A2 (pt) 2011-03-22
MX2008008905A (es) 2008-10-03
US20100168420A1 (en) 2010-07-01
CN100999524A (zh) 2007-07-18
EP1980562A1 (en) 2008-10-15
JP2009522380A (ja) 2009-06-11
AU2007204520A1 (en) 2007-07-19
ZA200805910B (en) 2009-10-28
CN100516067C (zh) 2009-07-22
WO2007079666A1 (en) 2007-07-19
KR20080094025A (ko) 2008-10-22
AU2007204520A2 (en) 2008-09-25
RU2419622C2 (ru) 2011-05-27
EP1980562A4 (en) 2010-10-27
RU2008132871A (ru) 2010-02-20
CA2636211A1 (en) 2007-07-19
US8362240B2 (en) 2013-01-29

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