UA99611C2 - Способ лечения дефицита внимания с гиперактивностью (adhd) и применение 4-[2-(4-метилфенилсульфанил)фенил]пиперидина для производства лекарственного средства - Google Patents

Способ лечения дефицита внимания с гиперактивностью (adhd) и применение 4-[2-(4-метилфенилсульфанил)фенил]пиперидина для производства лекарственного средства

Info

Publication number
UA99611C2
UA99611C2 UAA200910338A UAA200910338A UA99611C2 UA 99611 C2 UA99611 C2 UA 99611C2 UA A200910338 A UAA200910338 A UA A200910338A UA A200910338 A UAA200910338 A UA A200910338A UA 99611 C2 UA99611 C2 UA 99611C2
Authority
UA
Ukraine
Prior art keywords
treatment
methylphenylsulfanyl
adhd
piperidine
phenyl
Prior art date
Application number
UAA200910338A
Other languages
English (en)
Ukrainian (uk)
Inventor
Тине Брайан Стенсбьол
Зилке Миллер
Original Assignee
Х. Луннбэк А/С
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Х. Луннбэк А/С filed Critical Х. Луннбэк А/С
Publication of UA99611C2 publication Critical patent/UA99611C2/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4465—Non condensed piperidines, e.g. piperocaine only substituted in position 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/451—Non condensed piperidines, e.g. piperocaine having a carbocyclic group directly attached to the heterocyclic ring, e.g. glutethimide, meperidine, loperamide, phencyclidine, piminodine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Epidemiology (AREA)
  • Psychiatry (AREA)
  • Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)

Abstract

Описывается применение 4-[2-(4-метилфенилсульфанил)фенил]пиперидина и его кислотно-аддитивных солей для лечения дефицита внимания с гиперактивностью (ADHD), эндогенной депрессии, резистентной депрессии или резидуальных симптомов депрессии.
UAA200910338A 2007-03-20 2008-03-14 Способ лечения дефицита внимания с гиперактивностью (adhd) и применение 4-[2-(4-метилфенилсульфанил)фенил]пиперидина для производства лекарственного средства UA99611C2 (ru)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DKPA200700423 2007-03-20

Publications (1)

Publication Number Publication Date
UA99611C2 true UA99611C2 (ru) 2012-09-10

Family

ID=39575680

Family Applications (2)

Application Number Title Priority Date Filing Date
UAA200910338A UA99611C2 (ru) 2007-03-20 2008-03-14 Способ лечения дефицита внимания с гиперактивностью (adhd) и применение 4-[2-(4-метилфенилсульфанил)фенил]пиперидина для производства лекарственного средства
UAA200910359A UA97660C2 (ru) 2007-03-20 2008-03-14 Жидкие композиции солей 4-[2-(4-метилфенилсульфанил)фенил]-пиперидина

Family Applications After (1)

Application Number Title Priority Date Filing Date
UAA200910359A UA97660C2 (ru) 2007-03-20 2008-03-14 Жидкие композиции солей 4-[2-(4-метилфенилсульфанил)фенил]-пиперидина

Country Status (27)

Country Link
US (2) US20100144788A1 (ru)
EP (2) EP2139479B1 (ru)
JP (1) JP5388867B2 (ru)
KR (1) KR20090125775A (ru)
CN (2) CN101674830B (ru)
AR (1) AR065798A1 (ru)
AU (1) AU2008228639B2 (ru)
BR (1) BRPI0808831A2 (ru)
CA (1) CA2684556C (ru)
CL (1) CL2008000796A1 (ru)
CO (1) CO6220957A2 (ru)
CY (2) CY1113965T1 (ru)
DK (2) DK2139479T3 (ru)
EA (1) EA017407B1 (ru)
ES (2) ES2399305T3 (ru)
HR (1) HRP20130049T1 (ru)
IL (1) IL200954A (ru)
MX (1) MX2009009934A (ru)
MY (1) MY163537A (ru)
NZ (1) NZ579723A (ru)
PL (2) PL2139479T3 (ru)
PT (2) PT2139479E (ru)
RS (2) RS52676B (ru)
SI (1) SI2139479T1 (ru)
TW (1) TWI432194B (ru)
UA (2) UA99611C2 (ru)
WO (1) WO2008113360A2 (ru)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2007260356B2 (en) * 2006-06-16 2013-01-24 H. Lundbeck A/S Crystalline forms of 4- [2- (4-methylphenylsulfanyl) -phenyl] piperidine with combined serotonin and norepinephrine reuptake inhibition for the treatment of neuropathic pain
TWI432194B (zh) 2007-03-20 2014-04-01 Lundbeck & Co As H ４-〔２-（４-甲基苯硫基）苯基〕哌啶之新穎治療用途
SI2167085T1 (sl) * 2007-06-15 2014-05-30 H. Lundbeck A/S 4-(2-(4-metilfenilsulfanil)fenil)piperidin za zdravljenje sindroma razdraĺ˝ljivega äśrevesja (ibs)
TW200938194A (en) * 2007-12-14 2009-09-16 Lundbeck & Co As H Therapeutic uses of compounds having affinity to the serotonin transporter, serotonin receptors and noradrenalin transporter
US8920840B2 (en) * 2010-04-30 2014-12-30 Takeda Pharmaceutical Company Limited Enteric tablet
US9311462B1 (en) 2011-03-04 2016-04-12 Zynga Inc. Cross platform social networking authentication system
US8332488B1 (en) 2011-03-04 2012-12-11 Zynga Inc. Multi-level cache with synch
US10135776B1 (en) 2011-03-31 2018-11-20 Zynga Inc. Cross platform social networking messaging system
US8347322B1 (en) 2011-03-31 2013-01-01 Zynga Inc. Social network application programming interface
US8522137B1 (en) 2011-06-30 2013-08-27 Zynga Inc. Systems, methods, and machine readable media for social network application development using a custom markup language
WO2018002115A1 (en) 2016-07-01 2018-01-04 H. Lundbeck A/S Vortioxetine dosing regimes for fast onset of antidepressant effect
US20210393621A1 (en) 2018-10-26 2021-12-23 The Research Foundation For The State University Of New York Combination serotonin specific reuptake inhibitor and serotonin 1a receptor partial agonist for reducing l-dopa-induced dyskinesia

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR9911049A (pt) * 1998-05-22 2001-02-06 Lilly Co Eli Terapia combinada para tratamento de depressão resistente
UA81749C2 (ru) * 2001-10-04 2008-02-11 Х. Луннбек А/С производные фенилпиперазина как ингибиторы обратного захвата серотонинА
PT1635828E (pt) * 2003-04-04 2008-07-01 Lundbeck & Co As H Derivados de 4-(2-feniloxifenil) piperidina ou de 1,2,3,6-tetrahidropiridina como inibidores da recaptação da serotonina
HRP20080478T3 (hr) * 2003-04-04 2009-02-28 H. Lundbeck A/S Derivati 4-(2-fenilsulfanil-fenil)-piperidina kaoinhibitori ponovne pohrane serotonina
AR052308A1 (es) * 2004-07-16 2007-03-14 Lundbeck & Co As H Derivados de 2-(1h-indolilsulfanil)-arilamina y una composicion farmaceutica que contiene al compuesto
DE102006028034A1 (de) * 2006-06-14 2007-12-20 Leifheit Ag Bürste und Kehrgerät mit Bürste
AU2007260356B2 (en) * 2006-06-16 2013-01-24 H. Lundbeck A/S Crystalline forms of 4- [2- (4-methylphenylsulfanyl) -phenyl] piperidine with combined serotonin and norepinephrine reuptake inhibition for the treatment of neuropathic pain
TWI432194B (zh) 2007-03-20 2014-04-01 Lundbeck & Co As H ４-〔２-（４-甲基苯硫基）苯基〕哌啶之新穎治療用途
TWI405588B (zh) 2007-03-20 2013-08-21 Lundbeck & Co As H ４-〔２-（４-甲苯基硫基）-苯基〕哌啶之鹽類的液體調配物
TW200938194A (en) * 2007-12-14 2009-09-16 Lundbeck & Co As H Therapeutic uses of compounds having affinity to the serotonin transporter, serotonin receptors and noradrenalin transporter

Also Published As

Publication number Publication date
EA017407B1 (ru) 2012-12-28
ES2445400T3 (es) 2014-03-03
PL2139479T3 (pl) 2013-05-31
MX2009009934A (es) 2009-09-24
CY1113965T1 (el) 2016-07-27
CN101646438B (zh) 2012-04-11
US8507526B2 (en) 2013-08-13
WO2008113360A2 (en) 2008-09-25
RS52676B (sr) 2013-06-28
ES2399305T3 (es) 2013-03-27
CN101674830A (zh) 2010-03-17
US20100144788A1 (en) 2010-06-10
IL200954A (en) 2014-12-31
RS53138B (sr) 2014-06-30
HK1142007A1 (en) 2010-11-26
EP2139479A2 (en) 2010-01-06
PL2167085T3 (pl) 2014-08-29
MY163537A (en) 2017-09-15
CO6220957A2 (es) 2010-11-19
CL2008000796A1 (es) 2008-09-26
JP5388867B2 (ja) 2014-01-15
BRPI0808831A2 (pt) 2014-08-26
CN101674830B (zh) 2012-05-09
PT2139479E (pt) 2013-02-20
UA97660C2 (ru) 2012-03-12
EP2167085B1 (en) 2013-12-25
KR20090125775A (ko) 2009-12-07
CY1114774T1 (el) 2016-12-14
EP2167085A1 (en) 2010-03-31
DK2167085T3 (da) 2014-02-03
US20100137366A1 (en) 2010-06-03
JP2010521502A (ja) 2010-06-24
CN101646438A (zh) 2010-02-10
WO2008113360A3 (en) 2008-11-13
HRP20130049T1 (hr) 2013-02-28
AU2008228639A1 (en) 2008-09-25
AR065798A1 (es) 2009-07-01
TWI432194B (zh) 2014-04-01
IL200954A0 (en) 2010-05-17
TW200848032A (en) 2008-12-16
EP2139479B1 (en) 2012-12-12
CA2684556A1 (en) 2008-09-25
SI2139479T1 (sl) 2013-04-30
CA2684556C (en) 2013-01-08
PT2167085E (pt) 2014-02-17
AU2008228639B2 (en) 2012-12-13
DK2139479T3 (da) 2013-02-11
EA200970871A1 (ru) 2010-04-30
NZ579723A (en) 2011-07-29

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