US1865539A - Microtome - Google Patents
Microtome Download PDFInfo
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- US1865539A US1865539A US372587A US37258729A US1865539A US 1865539 A US1865539 A US 1865539A US 372587 A US372587 A US 372587A US 37258729 A US37258729 A US 37258729A US 1865539 A US1865539 A US 1865539A
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- Prior art keywords
- blade
- arms
- arm
- holder
- tension
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- Expired - Lifetime
Links
- 238000010276 construction Methods 0.000 description 2
- 230000007812 deficiency Effects 0.000 description 2
- 230000001788 irregular Effects 0.000 description 2
- 241000078511 Microtome Species 0.000 description 1
- 229910000831 Steel Inorganic materials 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 210000003205 muscle Anatomy 0.000 description 1
- 210000005036 nerve Anatomy 0.000 description 1
- 230000003534 oscillatory effect Effects 0.000 description 1
- 210000004872 soft tissue Anatomy 0.000 description 1
- 239000010959 steel Substances 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
Images
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/02—Devices for withdrawing samples
- G01N1/04—Devices for withdrawing samples in the solid state, e.g. by cutting
- G01N1/06—Devices for withdrawing samples in the solid state, e.g. by cutting providing a thin slice, e.g. microtome
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T83/00—Cutting
- Y10T83/929—Tool or tool with support
- Y10T83/9457—Joint or connection
Definitions
- the object of the invention is to provide improvements in microtomes, and particularly in the means whereby the actual cutting edge of the blade is maintained to all intents 5 and purposes unyieldingly in its holder or support, so that its predetermined shape or direction is positively maintained throughout the operation of cutting substantially any kind of material for which such a device is designed.
- microtome is an instrument used by various classes of research workers and students but principally those interested in the microscopic examination of micrometrically thin sections of biological and similar subjects. Such sections measure but a f-ew thousandths of a millimeter in thickness and have at times been produced as thin as one-,fifty-thousandths of an inch, or thereabouts.
- Fig.,l is a top plan view of the improved blade holder
- Fig. 2 is a similar view with the clamping element in withdrawn position
- Fig. 3 is a. section on the line 3.-3 of Fig. 1
- Fig. 4c is abottom pla-n view of the device shown in Fig. l
- Fig. 5 is a section also on the line 3,-3 of Fig. l, but showing a slightly modified form of the device.
- the blade holder comprises a body portion 1, the central portion 2 of which has what will be referred to as an upper surface 3, extending in a diagonal direction so .as to meet the normal under surface of the'body atlanredge 54C, laterally disposed upon the opposite sides of the central portion 2, the body being of any suitable shape sufficient to Vinsure rigidity and adord portions for clamping or otherwise securing the device in operative position in a machine.
- the ⁇ normal rear side of said central portion is provided withv spaced parallel arms 5 and 6, between which is pivotally supported upon a pin 7 the supporting arm 8 of a bladesecuring member, having a head portion 9, which is adapted to lie parallel with the surface 3 and secure a fiexible blade 10 therebetween, said head being tapered in a normal forward direction to a terminal edgeV portion 11 which registers with the edge 4 of the blade-supporting portion 2, said blade when in operative position providing a freely extending cutting edge 12, as clearly shown in the drawing.
- a link or auxiliary arm 14 Pivotally secured by any suitable means 13 to the normal under side of the arm 6 is a link or auxiliary arm 14, which at its opposite end is provided with a VU-shaped recess adapted to normally receive a lug or bolt 16, which cooperates with the pivotal means 13 to normally secure said link in subs-tantially tight sliding-fit relation with the under surface of said arms.
- the arm 8 of the clamping member is in turn provided with a bolt 17, having a head 18, provided with finger-engaging wings or pins 19, whereby when in operative position, as shown in full lines in Fig. 3, screwing said bolt downwardly until it extends through its supporting arm and engages the link 14, cau-ses a variable pressure of predetermined degree to be imposed by the head 9 upon the blade 10 betweensaid supporting surfaces.
- the bolt 17 is released until freeV of engagement with the link 14, after which said link is oscillated into the dot-and-dash position shown in Fig. 4, so that the arm 8 is then free to oscillate into its dot-and-dash position, as shown in Fig. 3, thereby removing the head 9 from its normal position adjacent to and in binding relation with the blade.
- a well-known type of blade has been illustrated as vbeing provided with spaced apertures :2O and 21.
- Through the aperture 20 normally extends a lug 22 ixedly carried preferably by the ysupporting section 2, though it might be carried by the clamping head 9.
- Through the second aperture 2l extends a lug or projection 23 carried by a lever 24, which is pivotally secured Vat 25 within a transversely extending recess 26 in the surface of the'blade-supporting portion 2 of the holder.
- the opposite end portion V27 of said lever ⁇ is normally engaged by a screw 28, having a preferably knurled finger-engaging and freely extending end portion 29.
- FIG. 5 Similar numerals are employed to designate parts which are substantially the same as those shown in F 3, but it will be noted that the upper face 39 of the central portion 2 of the holder is slightly concave, and that the oppositely disposed lower face 3l of the oscillatory head portion 9 is correspondingly convex, with the result that a blade secured therebetween is slightly flexed, in order that the freely projecting edge 12 lies more nearly in the plane of the under surface of said central portion 2 than is the case in that form of the device shown in Fig. 3. As a result of this construction the cutting head with a blade operatively supported thereby tends to permit the production of much thinner and more uniform cross sections, than is possible with that form of the device first described.
- a blade holder comprising -a body portion having a blade-supporting surface, a member pivoted to said body and lia-ving a surface opposed to said first surface, said ⁇ body and said member having arms together extending upon the side yof the pivot opposite to said surfaces, and means to ⁇ adj ust the ⁇ relative positionsof said arms to vary the pressure upon a blade between said surfaces.
- a blade holder comprising a body portion having a blade-supporting surface, a member pivoted to said body and having a surface opposed to said first surface, said body and said member having arms together extending upon the side of the pivot opposite to said surfaces, an auxiliary arin pivotally vcarried by one of ,said ⁇ armsV and means carried by the other of saidr arms and engaging said auxiliary arm when in operative position to adjust the relative positions 4of said arms to vary the pressure upon a blade between said surfaces.
- a blade holder comprising a body portion having a blade-supporting surface that is irregular, a member pivoted to said body and having a similarly shaped surface opposed to said first surface, said body and said member having arms together extending upon the side of the pivot opposite to said surfaces, and means to adjust the relative positions of said arms to vary the pressure upon and the shape of a blade between said surfaces.
- a blade holder comprising a body portion having a blade-supporting surface that is irregular, a member pivoted to said. body7 and operative with said surface to flex a blade into substantial conformity with said surface, said body and said member having arms together extending upon the side of the pivot opposite to said surfaces, and means carried by one arm and engaging the other arm to ⁇ adjust the relative positions of said arms to vary the pressure upon and the shape of a blade between said surfaces.
- a blade holder comprising a body portion having a blade-supporting surface provided with fixed and relatively movable projections, a member carried by said body and having a surface opposed to said first surface, means to secure said body and member together with a blade therebetween having edge portions in engagement with said projections, and means to adjust said movable projection with respect to said fixed projection to place upon the blade a tension.
- a blade holder comprising a body portion having a blade-supporting surface provided with fixed and relatively movable projections, a member pivoted to said body and having a surface opposed to said first surface, means to adj ustably secure said body and member together with a blade therebetween having edge portions in engagement with said projections, and means to ust said movable projection with respect to said xed projection to place upon theblade a variable longitudinal tension.
- a blade holder comprising a body portion having a blade-supporting surface, and a member pivoted to said body and having -a surface opposed to said first surface, said body and said member having arms together extending upon theside of the pivot opposite to said surfaces, one arm having a pivotal extension and the other arm carrying an adjustable screw engageable with said extension when in operative position to adjust the pressure upon a blade between said surfaces.
- a blade holder comprising a'body portion having a blade-supporting surface, a member pivoted to said body and having a surface opposed to said first surface, said body and said member having arms together extending upon the side of the pivot opposite to said'surfaces, one arm having spaced projections, a link movably mounted upon one projection and normally engageable with the other projection, and afscrew carried by the other varm and engageable with said link, to
- a blade holder comprising a body portion having a blade-supporting surface, a memberpivoted to said body and having a surface opposed to said first surface, said body and said member having arms together extending upon the side of th-e pivot opposite to said surfaces, one arm havingspaced pro jections, a link movably mounted upon one projection and normally engageable with the other projection, and a screw carried by the other arm and'engageable with said link, to vary the relative positions of said arms and thereby vary the pressure upon a blade between said surfaces, said link Vbeing movable upon the release of said screw free from said second projection to permit the second arm to vswing between the projections of the first arm in separating said surfaces to Vremove the blade from therebetween.
- a blade holder comprising a body portion having a blade-supporting surface, a member'carried by saidV body and having a surface opposed to saidfirst surface, means to hold one portion'of a blade between said surfaces relatively fixed longitudinally, and means to engage another portion of said blade and movable in the plane of the blade to place an adjustable longitudinal tension upon the same.
- a blade holder comprising a body portion having a blade-supporting surface, a member carried by said body and having a surface opposed to said first surface, means to hold one portion of a blade between said surfaces relatively fixed longitudinally, and
- a blade holder comprising a Vbody member having a bladesupporting surface
- Va second member carried bysaid body member andhaving a surface opposed to said first surface, means to hold one portion of a blade between said surfaces relatively fixed, a lever pivotally carried by one of said members and extending between them, saidlever having a blade-engaging portion, and adjustable means to oscillate said lever to impose upon said blade a tension in its own plane.
- a blade holder comprising a body member having a blade-supporting surface, a second member carried by said body member and having a surface opposed to saidviirst surface, an upstanding lug to hold one portion of a blade between said surfaces relatively fixed, a lever pivotally carried by one of said members and extending between'them, said lever having an upstanding blade-engaging lng, and a screw to oscillate said lever to impose upon said blade a tension in its own plane.
- a blade holder comprising a pair of pivoted members, means to secure one portion of a blade relatively fixed between said members, adjustable means to engage another portion of such blade and to impose thereupon a variable tension in the plane of the blade, and means to adjustably bind said members together to prevent undesired flexing of the blade due to said tension.
- a blade holder comprising a pair of pivoted members, a projection of one member being adaptedto engage an edge portion of a blade between said members, a lever carried by one of said members and having a projection adapted to engage another edge portion of such blade, means to adjustably oscillate said lever to tension said blade in its own plane, and means to adjustably clamp said members together to predetermine the permissible degree of flexing ofthe blade when under tension.
- a blade holder comprising a body portion having a curved blade-supporting surface, a member pivotally carried by said body and operative to force a flexible blade into conformity With said first surface, means to hold one portion of a blade between said surfaces relatively fixed longitudinally, bladeengaging means movable with respect to said first means and operative to place upon said blade a longitudinal tension, vand :means to adjustably clamp said body and said member together to curve a blade between them and to predetermine the permissible degree of flexing of such blade.
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- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Knives (AREA)
Description
July 5,1932. R. H. PlETzscH n 1,865,539
MI CROTOME Filed June 2l, 1929 H awJ; l @I Patented July 5, 1932-' RICHARD 4IPIIElIZSGI-I, 0F PHILADELPHIA, PENNSYLVANIA yi/HonofroMI-i y Application led .Tune 21,
The object of the invention is to provide improvements in microtomes, and particularly in the means whereby the actual cutting edge of the blade is maintained to all intents 5 and purposes unyieldingly in its holder or support, so that its predetermined shape or direction is positively maintained throughout the operation of cutting substantially any kind of material for which such a device is designed.
Primarily it should be understood that a microtome is an instrument used by various classes of research workers and students but principally those interested in the microscopic examination of micrometrically thin sections of biological and similar subjects. Such sections measure but a f-ew thousandths of a millimeter in thickness and have at times been produced as thin as one-,fifty-thousandths of an inch, or thereabouts. i
The cutting of such a section requires not only an extremely sharp edged blade or knife, but demands a high gradeof instrument as well. For this purpose the type of microtome knife heretofore employed has resembled a very heavy razor having concave opposite surfaces to produce the necessarily reinforced cutting edge. However, as certain tissues tend to rapidly dull a blade of even the finest grade of steel, a great amount of valuable time has been wasted by scientists in the frequent honing and stropping ofthe blade.
This deficiency has Vled to -the use of the much thinner and much less expensive dexible blades of the so-called safety-razor type, but all known attempts along this line have resulted in failure, except for the cutting of relatively soft tissue and that in not too thin sections. This is due tothe fact that the ordinary safety razor blade because of itsV thinness` vibrates, or more properly speaking fleXes, while passingV through a relatively ltough section such as through a bundle of muscles, nerves, gristle, or the like. Such deficiency has been definitelyovercome ,by securingV the usual thin and ordinarily very fleXibleblade between opposed surfaces of a clamp which imposes upon the blade a lateral or transverse strain or tension, while upon said blade there is simulta- 1929. Serial No. 372,587.
neously imposed a relatively high degree of longitudinal strain or tension, with the result that for all intents and purposes the cutting edge of the blade is positively maintained in its predetermined position and direction, and frequently to an even greater degree than the free edge portion of a relatively much heavier and therefore stier blade such as has heretofore been used as above described. Y
Thus, by employing. this improved blade holder a great saving of time is made possible, while the cost of the blades is very much less than those previously available.` Also, if -instead of alwaysreplacing a dulled blade by a new one,'the first blade is to be sharpened, it is well-known that many devices have been perfected for the automatic `and thorough grindingand honing of a exible safety-razor blade, which could not possibly be used, and of which there is no counterpart vfor use, in sharpening a rigid, relatively heavy blade of the character referred to.
Having in mind these objects thus broadly stated, the present invention comprises further detailsof construction and operation, which are fully brought out in the following description,v when read in conjunction with the accompanying drawing, in which Fig.,l is a top plan view of the improved blade holder; Fig. 2 is a similar view with the clamping element in withdrawn position; Fig. 3 is a. section on the line 3.-3 of Fig. 1; Fig. 4c .is abottom pla-n view of the device shown in Fig. l; and Fig. 5 is a section also on the line 3,-3 of Fig. l, but showing a slightly modified form of the device.
l'Referring to the drawing, the blade holder comprises a body portion 1, the central portion 2 of which has what will be referred to as an upper surface 3, extending in a diagonal direction so .as to meet the normal under surface of the'body atlanredge 54C, laterally disposed upon the opposite sides of the central portion 2, the body being of any suitable shape sufficient to Vinsure rigidity and adord portions for clamping or otherwise securing the device in operative position in a machine. The `normal rear side of said central portion is provided withv spaced parallel arms 5 and 6, between which is pivotally supported upon a pin 7 the supporting arm 8 of a bladesecuring member, having a head portion 9, which is adapted to lie parallel with the surface 3 and secure a fiexible blade 10 therebetween, said head being tapered in a normal forward direction to a terminal edgeV portion 11 which registers with the edge 4 of the blade-supporting portion 2, said blade when in operative position providing a freely extending cutting edge 12, as clearly shown in the drawing.
Pivotally secured by any suitable means 13 to the normal under side of the arm 6 is a link or auxiliary arm 14, which at its opposite end is provided with a VU-shaped recess adapted to normally receive a lug or bolt 16, which cooperates with the pivotal means 13 to normally secure said link in subs-tantially tight sliding-fit relation with the under surface of said arms. The arm 8 of the clamping member is in turn provided with a bolt 17, having a head 18, provided with finger-engaging wings or pins 19, whereby when in operative position, as shown in full lines in Fig. 3, screwing said bolt downwardly until it extends through its supporting arm and engages the link 14, cau-ses a variable pressure of predetermined degree to be imposed by the head 9 upon the blade 10 betweensaid supporting surfaces. In order to remove said blade for re'clamping, replacement, or readjustment, the bolt 17 is released until freeV of engagement with the link 14, after which said link is oscillated into the dot-and-dash position shown in Fig. 4, so that the arm 8 is then free to oscillate into its dot-and-dash position, as shown in Fig. 3, thereby removing the head 9 from its normal position adjacent to and in binding relation with the blade.
' It is also to be noted that it is preferable to provide the adjacent surfaces of the bladesupporting portion 2 and the head 9 with a slight degree of curvature adjacent to their free edge portions in order `to cause both the longitudinal and transversestiflening of they blade, in addition to the tension means hereinafter described. 'This also insures the blades cutting edge 12 projecting beneath the plane of the lower surface of the body l.
While any desired type of blades maybe used in this device, a well-known type of blade has been illustrated as vbeing provided with spaced apertures :2O and 21. Through the aperture 20 normally extends a lug 22 ixedly carried preferably by the ysupporting section 2, though it might be carried by the clamping head 9. Through the second aperture 2l extends a lug or projection 23 carried by a lever 24, which is pivotally secured Vat 25 within a transversely extending recess 26 in the surface of the'blade-supporting portion 2 of the holder. Y The opposite end portion V27 of said lever `is normally engaged by a screw 28, having a preferably knurled finger-engaging and freely extending end portion 29. Thus, when the blade has been positioned upon the supporting portion 2 and clamping head 9 secured in position with a certain initial pressure imposed thereby upon the blade, rotation of the screw head 29 causes the lever 24-27 to be moved upon the pivotal portion 25 in such manner that the distance between the centers of the lugs 22 and 23 is increased, thereby imposing upon the blade a distinct and, if desired, very great longitudinal tension, after which the remainder of the desired clamping tension may be imposed up on the blade by further tightening the bolt 17. Obviously, to release the blade, this series of operations is reversed, so that by reversely rotating the head 29, the screw 28 permits the lever lug 23 to approach the fixed lug 22 and release the blade as soon as the bolt 17 has also been released and the link 14 has been rotated into inoperative position.
Referring to Fig. 5, similar numerals are employed to designate parts which are substantially the same as those shown in F 3, but it will be noted that the upper face 39 of the central portion 2 of the holder is slightly concave, and that the oppositely disposed lower face 3l of the oscillatory head portion 9 is correspondingly convex, with the result that a blade secured therebetween is slightly flexed, in order that the freely projecting edge 12 lies more nearly in the plane of the under surface of said central portion 2 than is the case in that form of the device shown in Fig. 3. As a result of this construction the cutting head with a blade operatively supported thereby tends to permit the production of much thinner and more uniform cross sections, than is possible with that form of the device first described.
Having thus described my invention, what I claim and desire to protect by Letters Patent of the United States is l. A blade holder, comprising -a body portion having a blade-supporting surface, a member pivoted to said body and lia-ving a surface opposed to said first surface, said `body and said member having arms together extending upon the side yof the pivot opposite to said surfaces, and means to `adj ust the `relative positionsof said arms to vary the pressure upon a blade between said surfaces.
2. A blade holder, comprising a body portion having a blade-supporting surface, a member pivoted to said body and having a surface opposed to said first surface, said body and said member having arms together extending upon the side of the pivot opposite to said surfaces, an auxiliary arin pivotally vcarried by one of ,said` armsV and means carried by the other of saidr arms and engaging said auxiliary arm when in operative position to adjust the relative positions 4of said arms to vary the pressure upon a blade between said surfaces. Y
3. A blade holder, comprising a body portion having a blade-supporting surface that is irregular, a member pivoted to said body and having a similarly shaped surface opposed to said first surface, said body and said member having arms together extending upon the side of the pivot opposite to said surfaces, and means to adjust the relative positions of said arms to vary the pressure upon and the shape of a blade between said surfaces.
4:. A blade holder, comprising a body portion having a blade-supporting surface that is irregular, a member pivoted to said. body7 and operative with said surface to flex a blade into substantial conformity with said surface, said body and said member having arms together extending upon the side of the pivot opposite to said surfaces, and means carried by one arm and engaging the other arm to` adjust the relative positions of said arms to vary the pressure upon and the shape of a blade between said surfaces.
5. A blade holder, comprising a body portion having a blade-supporting surface provided with fixed and relatively movable projections, a member carried by said body and having a surface opposed to said first surface, means to secure said body and member together with a blade therebetween having edge portions in engagement with said projections, and means to adjust said movable projection with respect to said fixed projection to place upon the blade a tension.
6. A blade holder, comprising a body portion having a blade-supporting surface provided with fixed and relatively movable projections, a member pivoted to said body and having a surface opposed to said first surface, means to adj ustably secure said body and member together with a blade therebetween having edge portions in engagement with said projections, and means to ust said movable projection with respect to said xed projection to place upon theblade a variable longitudinal tension.
7. A blade holder, comprising a body portion having a blade-supporting surface, and a member pivoted to said body and having -a surface opposed to said first surface, said body and said member having arms together extending upon theside of the pivot opposite to said surfaces, one arm having a pivotal extension and the other arm carrying an adjustable screw engageable with said extension when in operative position to adjust the pressure upon a blade between said surfaces.
8. A blade holder, comprising a'body portion having a blade-supporting surface, a member pivoted to said body and having a surface opposed to said first surface, said body and said member having arms together extending upon the side of the pivot opposite to said'surfaces, one arm having spaced projections, a link movably mounted upon one projection and normally engageable with the other projection, and afscrew carried by the other varm and engageable with said link, to
vary the relative positions of said arms and thereby vary the pressure upon a blade between said surfaces. A i
9. A blade holder, comprising a body portion having a blade-supporting surface, a memberpivoted to said body and having a surface opposed to said first surface, said body and said member having arms together extending upon the side of th-e pivot opposite to said surfaces, one arm havingspaced pro jections, a link movably mounted upon one projection and normally engageable with the other projection, and a screw carried by the other arm and'engageable with said link, to vary the relative positions of said arms and thereby vary the pressure upon a blade between said surfaces, said link Vbeing movable upon the release of said screw free from said second projection to permit the second arm to vswing between the projections of the first arm in separating said surfaces to Vremove the blade from therebetween. y
lO. A blade holder, comprising a body portion having a blade-supporting surface, a member'carried by saidV body and having a surface opposed to saidfirst surface, means to hold one portion'of a blade between said surfaces relatively fixed longitudinally, and means to engage another portion of said blade and movable in the plane of the blade to place an adjustable longitudinal tension upon the same.
11. A blade holder, comprising a body portion having a blade-supporting surface, a member carried by said body and having a surface opposed to said first surface, means to hold one portion of a blade between said surfaces relatively fixed longitudinally, and
means to engage another portion of said blade Y and movablev in the plane of the blade to place an adjustable longitudinal tension upon the same inthe plane of the blade.
l2. A blade holder, comprising a Vbody member having a bladesupporting surface,
Va second member carried bysaid body member andhaving a surface opposed to said first surface, means to hold one portion of a blade between said surfaces relatively fixed, a lever pivotally carried by one of said members and extending between them, saidlever having a blade-engaging portion, and adjustable means to oscillate said lever to impose upon said blade a tension in its own plane.
13. A blade holder, comprising a body member having a blade-supporting surface, a second member carried by said body member and having a surface opposed to saidviirst surface, an upstanding lug to hold one portion of a blade between said surfaces relatively fixed, a lever pivotally carried by one of said members and extending between'them, said lever having an upstanding blade-engaging lng, and a screw to oscillate said lever to impose upon said blade a tension in its own plane.
14. A blade holder, comprising a pair of pivoted members, means to secure one portion of a blade relatively fixed between said members, adjustable means to engage another portion of such blade and to impose thereupon a variable tension in the plane of the blade, and means to adjustably bind said members together to prevent undesired flexing of the blade due to said tension.
l5. A blade holder, comprising a pair of pivoted members, a projection of one member being adaptedto engage an edge portion of a blade between said members, a lever carried by one of said members and having a projection adapted to engage another edge portion of such blade, means to adjustably oscillate said lever to tension said blade in its own plane, and means to adjustably clamp said members together to predetermine the permissible degree of flexing ofthe blade when under tension.
16. A blade holden-comprising a body portion having a curved blade-supporting surface, a member pivoted to said body and having a curved surface conforming Wit-h and opposed to said first surface, said body and said member having arms together extending upon the side of the pivot opposite to said surfaces, and means to adjustthe relative positions of said arms to vary the curvature and pressure upon a blade betvveensaid surfaces. i
17. A blade holder, comprising a body portion having a curved blade-supporting surface, a member pivotally carried by said body and operative to force a flexible blade into conformity With said first surface, means to hold one portion of a blade between said surfaces relatively fixed longitudinally, bladeengaging means movable with respect to said first means and operative to place upon said blade a longitudinal tension, vand :means to adjustably clamp said body and said member together to curve a blade between them and to predetermine the permissible degree of flexing of such blade..
In testimony whereof I have affixed my signature.
RICHARD H. PIETZSCH.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US372587A US1865539A (en) | 1929-06-21 | 1929-06-21 | Microtome |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US372587A US1865539A (en) | 1929-06-21 | 1929-06-21 | Microtome |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| US1865539A true US1865539A (en) | 1932-07-05 |
Family
ID=23468794
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| US372587A Expired - Lifetime US1865539A (en) | 1929-06-21 | 1929-06-21 | Microtome |
Country Status (1)
| Country | Link |
|---|---|
| US (1) | US1865539A (en) |
Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2439671A (en) * | 1944-02-16 | 1948-04-13 | Harvey N Ott | Knife holder for microtomes |
| US2875669A (en) * | 1952-11-06 | 1959-03-03 | Lkb Produkter Farbiksaktiebola | Microtome |
| US3227020A (en) * | 1963-09-23 | 1966-01-04 | Internat Equipment Co | Microtome blade holder and anti-roll means therefor |
| US3599523A (en) * | 1969-12-15 | 1971-08-17 | John E P Pickett | Disposable blade and holder for microtome |
| US3699830A (en) * | 1971-03-22 | 1972-10-24 | John E P Pickett | Method utilizing a disposable blade in microtome cutting |
| DE9015566U1 (en) * | 1990-11-14 | 1991-02-07 | Microm Laborgeräte GmbH, 6909 Walldorf | Microtome with a holder for a cutting knife |
| US20060185490A1 (en) * | 2005-02-23 | 2006-08-24 | Mincer Mathew T | Microtome blade |
| US20060225289A1 (en) * | 2005-04-08 | 2006-10-12 | Patents Holding Company | Sealant cutting tool with quick release, repositionable blade |
| US20100043612A1 (en) * | 2007-04-20 | 2010-02-25 | Feather Safety Razor Co., Ltd. | Replaceable blade for microtome and curl prevention plate |
| WO2022271908A1 (en) | 2021-06-23 | 2022-12-29 | 10X Genomics, Inc. | Chop-fix method and chopping device for preparing biological samples |
-
1929
- 1929-06-21 US US372587A patent/US1865539A/en not_active Expired - Lifetime
Cited By (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2439671A (en) * | 1944-02-16 | 1948-04-13 | Harvey N Ott | Knife holder for microtomes |
| US2875669A (en) * | 1952-11-06 | 1959-03-03 | Lkb Produkter Farbiksaktiebola | Microtome |
| US3227020A (en) * | 1963-09-23 | 1966-01-04 | Internat Equipment Co | Microtome blade holder and anti-roll means therefor |
| US3599523A (en) * | 1969-12-15 | 1971-08-17 | John E P Pickett | Disposable blade and holder for microtome |
| US3699830A (en) * | 1971-03-22 | 1972-10-24 | John E P Pickett | Method utilizing a disposable blade in microtome cutting |
| DE9015566U1 (en) * | 1990-11-14 | 1991-02-07 | Microm Laborgeräte GmbH, 6909 Walldorf | Microtome with a holder for a cutting knife |
| US20060185490A1 (en) * | 2005-02-23 | 2006-08-24 | Mincer Mathew T | Microtome blade |
| US7827894B2 (en) | 2005-02-23 | 2010-11-09 | Feather Safety Razor Co., Ltd. | Microtome blade |
| US20060225289A1 (en) * | 2005-04-08 | 2006-10-12 | Patents Holding Company | Sealant cutting tool with quick release, repositionable blade |
| US7308763B2 (en) * | 2005-04-08 | 2007-12-18 | Patents Holding Company | Sealant cutting tool with quick release, repositionable blade |
| US20100043612A1 (en) * | 2007-04-20 | 2010-02-25 | Feather Safety Razor Co., Ltd. | Replaceable blade for microtome and curl prevention plate |
| WO2022271908A1 (en) | 2021-06-23 | 2022-12-29 | 10X Genomics, Inc. | Chop-fix method and chopping device for preparing biological samples |
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