US3373601A - Device for the analysis of the sinking speed of blood corpuscles in a calibrated tube - Google Patents

Device for the analysis of the sinking speed of blood corpuscles in a calibrated tube Download PDF

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Publication number
US3373601A
US3373601A US476404A US47640465A US3373601A US 3373601 A US3373601 A US 3373601A US 476404 A US476404 A US 476404A US 47640465 A US47640465 A US 47640465A US 3373601 A US3373601 A US 3373601A
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United States
Prior art keywords
tube
container
blood
sealing lip
cylinder
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Expired - Lifetime
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US476404A
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English (en)
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Monn Stanislaus
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Individual
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Individual
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/04—Investigating sedimentation of particle suspensions
    • G01N15/05—Investigating sedimentation of particle suspensions in blood

Definitions

  • a device for filling an elongated, hollow calibrated tube for the purpose of analyzing the sedimentation rate of blood corpuscles having a resilient body which has an elongated recess therein opening outwardly at one end thereof, the diameter of said recess being slightly greater than the outer diameter of said calibrated tube.
  • the body has annular sealing means adjacent the open end thereof, the diameter of said sealing means being less than the outer diameter of said calibrated tube.
  • This invention relates to an apparatus for the analysis of the sinking speed of blood corpuscles in a calibrated tube which is filled to a reference mark by the blood.
  • the purpose of the invention is to provide a device by which the blood to be examined is filled into a cylinder, up to a reference mark on the tube also by means of a pistonlike insertion of the lower end of the tube, said cylinder being opened on the upper end and closed on the lower end, but whereby the mentioned disadvantages of the known device of this kind are avoided.
  • the device of the invention is mainly characterized in that the inner diameter of the cylinder is larger than the outer diameter of the tube and that the cylinder has an inwardly projecting, annular, resilient sealing lip at its 65 opening.
  • the normal diameter of the sealing lip when the tube is withdrawn is smaller than the outer diameter of the tube and when said tube is inserted into the cylinder the sealing lip contacts sealingly the outer surface of the tube.
  • the cylinder is a container consisting of rubber-elastic material
  • said container together with the annular sealing lip consists of a single integral piece of material.
  • FIGURE 1 shows a cylinder with a sealing lip formed as a rubber container and a measuring tube inserted into the cylinder, partially in an elevational view and partially in a vertical section;
  • FIGURE 2 is an analogous sectional view of the cylinder with the sealing lip alone;
  • FIGURE 3 is an elevational view of the cyilnder
  • FIGURE 4 is a cross-sectional view taken on the line IV-IV in FIGURE 2;
  • FIGURE 5 which is drawn in a smaller scale, shows a holder with inserted cylinders, in one of which a measuring tube is inserted.
  • the calibrated measuring tube 10 shown in FIGURE 1 and 5, which is made of glass, is in common use and available in the trade pertaining hereto.
  • the tube is open on both ends and has a reference mark 11, up to which the blood to be examined is introduced into the tube. Below the reference mark 11 the tube carries a millimeter scale beginning with the reference mark.
  • the lower part of the tube 10 is inserted into a cylinder, which is a rubber-elastic body or container for instance made out of caoutchouc.
  • a cylinder which is a rubber-elastic body or container for instance made out of caoutchouc.
  • the container 20 is closed by a bottom 21, while it has an opening 22 on the top.
  • annular sealing lip 23 which together with the container 2% is made of the same piece of material and therefore is also rubber-elastic or resilient.
  • the diameter of the sealing lip 23 is less than the outer diameter of the tube 10.
  • the inner diameter of the container 2t) is somewhat larger than the outer diameter of the tube 10, as shown clearly in FIGURE 1.
  • Above the sealing lip 23 the opening 22 has an enlarged, fannelshaped mouth 24.
  • the upper end part of the container 2% is reinforced by providing thickenings of material at the outer surface of the container, namely a peripheral rib 25 at the upper end of the container 20, and several longitudinal ribs 25 originating at the peripheral rib 25, the longitudinal ribs also extending outwardly, mainly shown in FIGURES 3 and 4.
  • the device has a holder (FIGURE 5), which comprises a block 31 with several vertical bores 32, each for receiving a container 243.
  • the already mentioned longitudinal ribs 26 of the container 20 constitute a base to support the container at the upper end of the respective bores 32, so that the containers 20 being inserted into the bores 32, each hangs in a vertical position.
  • the blood to be examined is taken directly from the syringe, which was used for taking the blood sample, and injected into an empty container 20, so that the liquid level is slightly below the sealing lip 23.
  • a clean measuring tube 10 is slipped through the opening 22 into the container 20, the funnel-like enlarged month 24 making entry thereof very easy.
  • the sealing lip 23 is pressed outwardly elastically by the tube 10, whereby a liquid-tight sealing contact of the sealing lip 23 with the outer surface of the tube 10 is assured. If the tube It) is further pushed into the container 20, a part of the blood is displaced. Since the sealing lip 23 prevents escape of the blood along the outer surface of the tube 10 effectively, the displaced blood rises inwardly in the tube 10.
  • the tube 10 is pushed into the container 20 sufficiently until the top of the blood column has exactly reached the reference mark 11 of the tube. Because of the elastic stress of the sealing lip 23, the tube 10 is automatically locked in position relative to the container 20. The container 20 is then put into the holder 30. Since the container 20 is vertically supported in the holder 30, the tube 10 also has a position which is at least almost vertical. The measuring of the sinking speed of the blood corpuscles can now be conducted in the known and usual way.
  • the tube It can easily be pulled out of the container 20, whereafter these two parts can be cleaned easily and if desired can be sterilized by heating. If the blood in the container 20 and in the tube 10- is dried because of a too long waiting time, the container 20 still can be pulled from the tube 10 without complications, because there is enough space between the outer surface of the tube and the inner wall of the container to effect a crumbling of the blood crust through a Whipping movement of the container against the tube. Since the container 20 in the described example consists of rubber-elastic material, the container can be deformed by a sideways compressing such that any possible existing blood crust crumbles fast.
  • the new apparatus has a further advantage, that commercial tubes 10 without an outer grinding can be used, because of the flexibility of the sealing lip 23, the outer diameter of the tube 10 may have the usual tolerance, without damaging the effectiveness of the apparatus.
  • Another advantage results from the fact that the tubes 10 without an outer grinding and the container 20 having a resilient sealing lip 23 can be manufactured at a more favorable price than can tubes and cylinders which are ground to each other.
  • no additional means for holding and securing of the tube 10 with respect to the container 20 are necessary, since the sealing lip 23, due to its elastic stress, automatically holds the tube 10 in position.
  • a device for analyzing the sedimentation rate of blood corpuscles comprising:
  • a body having an elongated, cylindrical recess therein, said recess being closed at one end and open at the other end thereof, the diameter of said recess being slightly greater than the outer diameter of said calibrated tube and the length of said tube being greater than the length of said recess so that said tube can slide axially in said recess toward said closed end thereof and said tube will function like a piston to displace the blood in said recess upwardly into said tube;
  • annular sealing lip means mounted on said body adjacent said open end thereof and projecting inwardly from the wall of said recess, the diameter of said lip means being slightly less than said outer diameter of said calibrated tube, the lip means being of relatively small axial thickness and being flexible so that the tube can be forced therethrough and the outer surface of said tube will sealingly slideably engage said sealing lip means to seal the interior of said recess.
  • a device in which the body has a funnel-like enlarged mouth (24) extending upwardly from said lip means and having wall portions converging toward said lip means.
  • a device in which said other end of said body (20) is reinforced by thickenings of material (25, 26) provided on the outer surface of the said body.
  • a device in which there is provided adjacent said other end of said body (20) an outwardly projecting peripheral rib (25), and a plurality of circumferentially spaced, radially outwardly projecting longitudinal ribs (26) extending from said peripheral rib on the outer surface of said body partway toward said one end thereof.
  • a device including a holder for holding said device, the thickenings of the material ('26) forming a base to support the body (20) in a vertical position in said holder (-30).
  • a device in which the holder (30) is a block (31) having several bores (32) therein for receiving one body (20) each, which bodies are each supported on the upper end of each respective bore by said thickenings of material (26).

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
US476404A 1964-08-05 1965-08-02 Device for the analysis of the sinking speed of blood corpuscles in a calibrated tube Expired - Lifetime US3373601A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH1032664A CH417158A (de) 1964-08-05 1964-08-05 Vorrichtung zum Bestimmen der Senkungsgeschwindigkeit von Blutkörperchen in einem kalibrierten Röhrchen

Publications (1)

Publication Number Publication Date
US3373601A true US3373601A (en) 1968-03-19

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ID=4361998

Family Applications (1)

Application Number Title Priority Date Filing Date
US476404A Expired - Lifetime US3373601A (en) 1964-08-05 1965-08-02 Device for the analysis of the sinking speed of blood corpuscles in a calibrated tube

Country Status (6)

Country Link
US (1) US3373601A (de)
AT (1) AT251754B (de)
CH (1) CH417158A (de)
FR (1) FR1445844A (de)
GB (1) GB1085978A (de)
NL (1) NL148410B (de)

Cited By (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3824841A (en) * 1971-02-08 1974-07-23 Coulter Electronics Method for sedimentation study
JPS5034283U (de) * 1973-07-24 1975-04-12
US3910103A (en) * 1973-05-23 1975-10-07 Ewald Rose Medical apparatus for measuring blood sedimentation
JPS52101185U (de) * 1976-01-29 1977-08-01
JPS5637560A (en) * 1979-09-01 1981-04-11 Sarstedt Kunststoff Blood precipitation device
EP0108724A2 (de) 1982-11-05 1984-05-16 L.P. ITALIANA S.p.A. Vorrichtung zur Messung der Sedimentationsgeschwindigkeit der Bluterythrocyten
US4545237A (en) * 1983-02-02 1985-10-08 Gerard Poncept Apparatus for blood analysis
US4592227A (en) * 1982-12-17 1986-06-03 Gerard Poncept Apparatus for analysis of blood
WO1997029377A1 (en) * 1996-02-11 1997-08-14 Altay Ender Babuer A rapid method of obtaining blood sedimentation rate
US5731512A (en) * 1996-09-16 1998-03-24 Lewy, Deceased; Henry Method for quick estimation of erythrocyte sedimentation rate with capillary tubes lined with preformed anticoagulant, mounted in an oblique position, and supported on a specially designed stand
US5939023A (en) * 1993-01-19 1999-08-17 Thermogenesis Corp. Fibrinogen processing apparatus method and container
US20040185570A1 (en) * 2003-03-21 2004-09-23 Bouboulis Denis A. Erythrocyte sedimentation rate (ESR) test measurement instrument of unitary design and method of using the same
US20060216829A1 (en) * 2003-03-21 2006-09-28 Denis Bouboulis Erythrocyte sedimentation rate (ESR) test measurement instrument of unitary design and method of using the same

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE8814379U1 (de) * 1988-11-17 1989-02-09 Ritter-Plastic GmbH, 8933 Untermeitingen Gerät zur Blutsenkung

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2000501A (en) * 1934-04-26 1935-05-07 David E Wade Ink well and pen filling device
US2097571A (en) * 1935-08-26 1937-11-02 Kimble Glass Co Pipette
US2263845A (en) * 1939-05-08 1941-11-25 Claude L Hartsell Plastic dispensing combination
DE1104225B (de) * 1959-04-02 1961-04-06 Kirchner & Wilhelm Geraet zur Bestimmung der Blutkoerperchensenkungsgeschwindigkeit

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2000501A (en) * 1934-04-26 1935-05-07 David E Wade Ink well and pen filling device
US2097571A (en) * 1935-08-26 1937-11-02 Kimble Glass Co Pipette
US2263845A (en) * 1939-05-08 1941-11-25 Claude L Hartsell Plastic dispensing combination
DE1104225B (de) * 1959-04-02 1961-04-06 Kirchner & Wilhelm Geraet zur Bestimmung der Blutkoerperchensenkungsgeschwindigkeit

Cited By (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3824841A (en) * 1971-02-08 1974-07-23 Coulter Electronics Method for sedimentation study
US3910103A (en) * 1973-05-23 1975-10-07 Ewald Rose Medical apparatus for measuring blood sedimentation
JPS5034283U (de) * 1973-07-24 1975-04-12
JPS52101185U (de) * 1976-01-29 1977-08-01
JPS5637560A (en) * 1979-09-01 1981-04-11 Sarstedt Kunststoff Blood precipitation device
EP0108724A2 (de) 1982-11-05 1984-05-16 L.P. ITALIANA S.p.A. Vorrichtung zur Messung der Sedimentationsgeschwindigkeit der Bluterythrocyten
US4622847A (en) * 1982-11-05 1986-11-18 L.P. Italiana S.P.A. Apparatus for measuring the rate of erythrosedimentation of the blood
EP0108724A3 (en) * 1982-11-05 1986-02-05 L.P. Italiana S.P.A. Apparatus for measuring the rate of erythrosedimentation of the blood
US4592227A (en) * 1982-12-17 1986-06-03 Gerard Poncept Apparatus for analysis of blood
US4545237A (en) * 1983-02-02 1985-10-08 Gerard Poncept Apparatus for blood analysis
US5939023A (en) * 1993-01-19 1999-08-17 Thermogenesis Corp. Fibrinogen processing apparatus method and container
WO1997029377A1 (en) * 1996-02-11 1997-08-14 Altay Ender Babuer A rapid method of obtaining blood sedimentation rate
US5731512A (en) * 1996-09-16 1998-03-24 Lewy, Deceased; Henry Method for quick estimation of erythrocyte sedimentation rate with capillary tubes lined with preformed anticoagulant, mounted in an oblique position, and supported on a specially designed stand
US20040185570A1 (en) * 2003-03-21 2004-09-23 Bouboulis Denis A. Erythrocyte sedimentation rate (ESR) test measurement instrument of unitary design and method of using the same
US6974701B2 (en) 2003-03-21 2005-12-13 Hemovations, Llc Erythrocyte sedimentation rate (ESR) test measurement instrument of unitary design and method of using the same
US20060030051A1 (en) * 2003-03-21 2006-02-09 Bouboulis Denis A Erythrocyte sedimentation rate (ESR) test measurement instrument of unitary design and method of using the same
US20060216829A1 (en) * 2003-03-21 2006-09-28 Denis Bouboulis Erythrocyte sedimentation rate (ESR) test measurement instrument of unitary design and method of using the same

Also Published As

Publication number Publication date
AT251754B (de) 1967-01-25
NL148410B (nl) 1976-01-15
CH417158A (de) 1966-07-15
FR1445844A (fr) 1966-07-15
NL6510103A (de) 1966-02-07
GB1085978A (en) 1967-10-04
DE1598755B1 (de) 1971-12-09

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