US3465748A - Device and method for treating vascular and other diseases of extremities - Google Patents

Device and method for treating vascular and other diseases of extremities Download PDF

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Publication number
US3465748A
US3465748A US589327A US3465748DA US3465748A US 3465748 A US3465748 A US 3465748A US 589327 A US589327 A US 589327A US 3465748D A US3465748D A US 3465748DA US 3465748 A US3465748 A US 3465748A
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extremity
pressure chamber
extremities
blood
decompression
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US589327A
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Vasily Afanasievich Kravchenko
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61HPHYSICAL THERAPY APPARATUS, e.g. DEVICES FOR LOCATING OR STIMULATING REFLEX POINTS IN THE BODY; ARTIFICIAL RESPIRATION; MASSAGE; BATHING DEVICES FOR SPECIAL THERAPEUTIC OR HYGIENIC PURPOSES OR SPECIFIC PARTS OF THE BODY
    • A61H9/00Pneumatic or hydraulic massage
    • A61H9/005Pneumatic massage
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61HPHYSICAL THERAPY APPARATUS, e.g. DEVICES FOR LOCATING OR STIMULATING REFLEX POINTS IN THE BODY; ARTIFICIAL RESPIRATION; MASSAGE; BATHING DEVICES FOR SPECIAL THERAPEUTIC OR HYGIENIC PURPOSES OR SPECIFIC PARTS OF THE BODY
    • A61H9/00Pneumatic or hydraulic massage
    • A61H9/005Pneumatic massage
    • A61H9/0071Pneumatic massage by localized pressure, e.g. air streams or jets

Definitions

  • This invention relates to a method whereby vascular diseases of the extremities such as obliterating endarteritis (Endarteritis obliterans) as well as other diseases affecting the human extremities, e.g. rheumatism, are treated, and likewise to a device for carrying the method into effect.
  • vascular diseases of the extremities such as obliterating endarteritis (Endarteritis obliterans) as well as other diseases affecting the human extremities, e.g. rheumatism
  • the invention is concerned with both the method and the device for treating the aforementioned afllictions of the human extremities according to which the latter are put into a pressure chamber provided in the device and treated by an active (arterial) hyperemia and the creation of a differential barometric pressure between the extremity and the pressure chamber in case of decompression, and between the pressure chamber and the extremity in case of compression.
  • Vasotrein the light iron-made extremities
  • the devices Vasotrein are employed for 3,465,748 Patented Sept. 9, 1969 carrying the above method into effect, these devices be ing designed upon the principle of the apparatus of passive hyperemia which have been described in the magazine Medizinal-Markt, 1958, No. 9, pp. 321-322 published in German Federative Republic as well as in a prospectus issued by the firm Franz Itting, Ludwigsstadt, Bavaria, GFR.
  • the abovementioned device is essentially a pressure chamber made of a transparent material and on one of its sides provided with a locking chamber and an aircushion for pressurizing the extremity contained in the pressure chamber; provision is made inside the latter of a horizontal support for positioning the arm or leg being treated.
  • Both the method and the device mentioned afore find application in treating extremities affected with vascular diseases (both arterial and venous) of various origin and etiology which do not respond to any other therapeutic methods of treatment, the employment of the method in each particular case being the function of the kind, form and the degree of gravity of the disease being cured.
  • the above-said method may be considered to be resorted to for treating the following diseases (as stated in the above-mentioned prospectus of the firm Franz Itting): atherosclerosis, intermittent claudication, endoangiitis, Buergers disease, Raynauds disease, Sudecks disease, the initial stage of gangrene, frost-bite, joint deformity (deformatio articularis), posttraumatic lesions of vessels, circulatory disturbance due to thrombosis, or thrombophlebitis, varicose ulcer of the leg (ulcus cruris), varicosis, postpoliomyelitic paralysis.
  • atherosclerosis intermittent claudication, endoangiitis, Buergers disease, Raynauds disease, Sudecks disease, the initial stage of gangrene, frost-bite, joint deformity (deformatio articularis), posttraumatic lesions of vessels, circulatory disturbance due to thrombosis, or throm
  • the above-mentioned method of treatment due to too small difference between the barometric pressures of the extremity and that within the pressure chamber and low duration of decompression and compression phases (4 to 6 minutes), enables only the pumping of blood over from place to place, i.e. sucking it from the organism into the veins of the extremity in case of decompression phase, and expelling the blood back into the organism in case of compression phase, thereby affording rubbing massage to the tissues and blood vessels of the affected extremity.
  • no increase of gas exchange within the cells of hypoxic tissues takes place during decompression phase whereas in the course of compression phase it is suppressed sharply during 7-10 minutes that the curing procedure lasts.
  • the aforesaid method is known to provoke passive hyperemia in the affected extremity, this being due to the fact that while decompression phases are being built up, only the arterial blood inflow towards the veins takes place, and the venous blood outflow during decompression is passive; thus, in order to intensify the outflow of blood from the veins, compression phases are created in the course of the curing procedure. As a result, the outflow of venous blood increases whereas the inflow of arterial blood during compression phases becomes passive.
  • an active (arterial) hyperemia is created in the affected extremity contained in a pressure chamber, the negative barometric pressure inside said chamber being within the range of 680 to 400 mm. Hg, thus giving no possibility for the active hyperemia to be converted into the passive one.
  • a special stop capable of retaining the extremity fixed in position on a support contained within the pressure chamber, both the support and the stop being so made as to be free to travel in longitudinal direction with respect to the pressure chamber, and can be set in any predetermined position as to the chamber length by means of a locking device.
  • the abovesaid device for locking i position the support with the stop retaining the extremity is essentially a rack (a toothed rack in the case of preferred embodiment) which is made fast on the wall of the pressure chamber and a spring-loaded dog which is coupled to said support and is capable of engaging said toothed rack when pressing upon the support with the heel of the leg or with the first of the arm being treated.
  • flexible tying means be provided on the outside of said chamber, such as straps with which the patient is retained in place during the procedure.
  • a device which is employed for practicing the proposed method of treatment is essentially a cylindrical pressure chamber 1 made of a transparent material and provided at both end faces with air-tight flanges 2 and 3.
  • the flange 2 has an opening for the extremity to pass into the pressure chamber 1 and a hollow ring '4 with a hollow flexible collar 5 for pressurizing the extremity contained within the pressure chamber 1.
  • the ring which is inserted into the opening in the flange 2 is so selected as to suit the diameter of the extremity being treated.
  • Communicating with the hollow space of the aforesaid collar 5 is a flexible bulb 6 capable of inflating said space with air whereas provision is made on the flange 2 for a valve 7 for regulating the pressure inside the hollow space of the collar '5.
  • a horizontal support 8 mounted on guides 10 along which said support is free to move in longitudinal direction with respect to said chamber, a stop 9 being provided on said hori- Zontal support to hold in place the extremity being treated.
  • the support 8 is connected to a spring-loaded dog 11 which is capable of being engaged with a toothed rack 12 when pressing upon said support, said toothed rack being made fast on the wall of said pressure chamber beneath the support 8.
  • the spring-loaded dog 11 and the toothed rack 12 in conjunction with each other form a locking device with which the support 8 can be locked in any preset position within the pressure chamber with respect to the length thereof.
  • the pressure chamber 1 is mounted on a carriage 13 which at its front is provided with a device 14 for lifting the chamber 1 which is needed for convenient disposition of the extremity under treatment.
  • An electrically driven pump 15 capable of building up a pressure inside the pressure chamber 1 can be mounted on a control board.
  • the patient should be subjected to a comprehensive examination by way of general analyses as well as to special investigations such as thermometry of the skin in the affected extremity, arterial oscillography, capillaroscopy, plethysmography as well as testing for oxygen content in the arterial and venous blood. According to indications thus obtained the kind and stage of the disease as well as its prognosis can be judged.
  • the ring 4 complete with collar *5 is to be so selected as to suit the size of the affected extremity, e.g. the leg, whereupon the latter is placed into the pressure chamber 1 so as to slightly touch the surface of the collar 5 of the ring 4. Then by pressing upon the heel rest of the support 8, the dog 11 is made to engage the toothed rack 12 whereby the extremity is fixed in position relative to the pressure chamber 1; this done, one should inflate the collar 5 of the ring 4 with air by manipulating the bulb 6 until the slight touch of the collar 5 and the surface of the extremity is attained.
  • the affected extremity e.g. the leg
  • the collar 5 expands and compresses the extremity; in such cases one should open the valve 7 and bleed the air away from the collar until the atmospheric air starts inflowing slightly into the pressure chamber through the contact area of the collar and the extremity which is indicated by a pressure gauge 18; after this the collar 5 is again inflated by using the bulb 6 until the former touches the surface of the extremity, taking care not to constrict the blood vessels excessively which can be easily checked by pressing upon the collar with the finger.
  • the procedure is terminated in the third phase with a decompression which lasts 5 to '7 minutes.
  • the main curative factor in the method involved consists in a decompression applied for 10 to 20 minutes since only this can intensify gas exchange in the cells and exert a curative effect upon the vessels whereas compression, on the contrary, suppresses gas exchange and therefore, affords only massotherapeutic effect and eliminates oedema of the extremity.
  • the initial two procedures are trial periods, in the course of which the necessary parameters of the curing procedure are selected.
  • the duration of decompression phases is administered to be the minimum, that is from 680 to 640 mm. Hg.
  • the degree of decompression is gradually increased by 5 or 10 mm. Hg until reaching the value which depends upon the kind and stage of the disease as well as upon the predetermined course of treatment.
  • the treatment procedure is preferably conducted with the patient inhaling oxygen.
  • the first coarse of treatment consists of 12 or 15 procedures, the maximum dosing of the negative pressure being within 680 to 635 mm. Hg.
  • the range of decompression in the initial two (trial) procedures is prescribed to be from 680 to 630 mm. Hg, and subsequently, from 645 to 580 mm. Hg, the duration of treatment being from 30 to 35 procedures.
  • the method of treatment described hereinabove is likewise applicable for curing the initial stage of hypertension in atherosclerosis of the human extremities.
  • the degree of decompression prescribed in treating polyarthritis infectiosa deformans ranges within 680 to 600 mm. Hg (with the leg bound up in case of weak veins), the number of procedures totalling up to 25 or 30.
  • the device of the present invention is likewise effective in treating torpid wounds and trophic ulcers where necessity arises of binding up the extremity with an aseptic bandage and using cotton wool. Considerable improvement and disappearing of painful sensations occur even after the initial 2-3 procedures while the complete recuperation comes after 15 to procedures, the results of treatment being most durable and persistent.
  • a method of treating vascular and other diseases of the extremities comprising placing the affected extremity in a pressure chamber, producing active hyperemia in said extremity while producing a negative pressure in the pressure chamber of 400 to 680 mm. Hg for increasing the difference in the partial pressures of oxygen in the blood and in the cells of tissues of said extremity to intensify gas exchange in the cells of hypoxic tissues, While preventing the abovesaid active hypermia from converting into a passive one during the period in which the extremity is in said pressure chamber.
  • a device for treating vascular and other diseases of extremities comprising: a pressure chamber adapted for receiving the affected extremity; a flexible collar on one side of said pressure chamber for pressurizing an extremity placed in said chamber; a support in the chamber for the extremity, means mounting said support within said pressure chamber for free longitudinal movement therein; stop means on said support for the extremity to bear against, and a locking device within said pressure chamber for holding said support in a preset longitudinal location within said pressure chamber, said locking device comprising a toothed rack in said pressure chamber, and a spring-loaded dog coupled to said support and engageable with said rack while pressing upon said support.
  • stop means is connected to said spring-loaded dog and is locked in position by the engagement of said dog with said rack.

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  • Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rehabilitation Therapy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Orthopedics, Nursing, And Contraception (AREA)
  • Medicinal Preparation (AREA)
US589327A 1966-10-25 1966-10-25 Device and method for treating vascular and other diseases of extremities Expired - Lifetime US3465748A (en)

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US58932766A 1966-10-25 1966-10-25

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CH (1) CH467618A (de)
FR (1) FR1499586A (de)
GB (1) GB1172077A (de)

Cited By (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4269175A (en) * 1977-06-06 1981-05-26 Dillon Richard S Promoting circulation of blood
US4738249A (en) * 1985-03-01 1988-04-19 The Procter & Gamble Company Method and apparatus for augmenting blood circulation
US20030032904A1 (en) * 2000-01-18 2003-02-13 Norbert Egger Fitness device in the form of a garment
US20030125649A1 (en) * 2001-10-31 2003-07-03 Mcintosh Laura Janet Method and system apparatus using temperature and pressure for treating medical disorders
US20030125646A1 (en) * 2001-12-29 2003-07-03 Whitlock Russell Ward Device and method for relieving pain
US20030216672A1 (en) * 2002-05-15 2003-11-20 The Research Foundation Of State University Of New York System and method for healing skin injuries
US20050027218A1 (en) * 2002-12-31 2005-02-03 Marius Filtvedt Device for applying a pulsating pressure to a local region of the body and applications thereof
US20050070405A1 (en) * 2001-10-02 2005-03-31 Norbert Egger Fitness device
US20050148913A1 (en) * 2004-01-02 2005-07-07 Weston Richard S. Reduced pressure wound treatment appliance
US20050261615A1 (en) * 2004-05-21 2005-11-24 Richard Scott Weston Hypobaric chamber treatment system
US20060211958A1 (en) * 2005-03-15 2006-09-21 Syneron Medical Ltd. Method and device for soft tissue treatment
US20070260110A1 (en) * 2002-08-22 2007-11-08 Koenig J F Noninvasive angioplasty using momentary vacuum therapy
US7708724B2 (en) 2004-04-05 2010-05-04 Blue Sky Medical Group Incorporated Reduced pressure wound cupping treatment system
US20100152821A1 (en) * 2008-12-16 2010-06-17 Thermanor As Portable patient temperature adjustment apparatus and method
US20100152633A1 (en) * 2008-12-16 2010-06-17 Thermanor As Portable patient temperature adjustment apparatus and method
US7776028B2 (en) 2004-04-05 2010-08-17 Bluesky Medical Group Incorporated Adjustable overlay reduced pressure wound treatment system
US7846141B2 (en) 2002-09-03 2010-12-07 Bluesky Medical Group Incorporated Reduced pressure treatment system
US7909805B2 (en) 2004-04-05 2011-03-22 Bluesky Medical Group Incorporated Flexible reduced pressure treatment appliance
US8062272B2 (en) 2004-05-21 2011-11-22 Bluesky Medical Group Incorporated Flexible reduced pressure treatment appliance
US8100887B2 (en) 2004-03-09 2012-01-24 Bluesky Medical Group Incorporated Enclosure-based reduced pressure treatment system
WO2012011927A1 (en) 2010-07-23 2012-01-26 Munoz Emilio A Leg constriction apparatus for promoting blood circulation
US8287474B1 (en) * 2002-08-22 2012-10-16 Koenig J Frank Method and apparatus for noninvasively increasing whole body blood flow and noninvasive physical exercise of limbs from the outside and from within the limb to treat diseases throughout the body
US8398614B2 (en) 2002-10-28 2013-03-19 Smith & Nephew Plc Apparatus for aspirating, irrigating and cleansing wounds
US8569566B2 (en) 2003-10-28 2013-10-29 Smith & Nephew, Plc Wound cleansing apparatus in-situ
US8926592B2 (en) 2003-10-28 2015-01-06 Smith & Nephew Plc Wound cleansing apparatus with heat
US20170360649A1 (en) * 2016-06-21 2017-12-21 Otivio As Post-surgical obstruction treatment recovery and rehabilitation therapy
US10058642B2 (en) 2004-04-05 2018-08-28 Bluesky Medical Group Incorporated Reduced pressure treatment system
US20190099312A1 (en) * 2017-09-29 2019-04-04 Otivio As Medical pressure therapy device and components thereof
WO2019064288A1 (en) * 2017-09-29 2019-04-04 Otivio As MEDICAL DEVICE FOR PRESSURE THERAPY AND ITS ELEMENTS
USD889634S1 (en) 2018-08-10 2020-07-07 Otivio As Pressure control unit
USD900996S1 (en) 2017-10-16 2020-11-03 Otivio As Pressure chamber
US10940075B2 (en) 2017-09-29 2021-03-09 Otivio As Medical pressure therapy device and components thereof
US20210393472A1 (en) * 2020-06-22 2021-12-23 Otivio As Pressure therapy methods and devices for treating spasticity
US11259985B2 (en) 2017-09-29 2022-03-01 Otivio As Medical pressure therapy device and components thereof
US20230023986A1 (en) * 2019-12-31 2023-01-26 Nuwelilis, Inc. Venous blood flow stimulator for extracorporeal therapy

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2302810B (en) * 1995-07-05 1999-06-16 Lakeside Eng Ltd Variable pressure chamber

Citations (2)

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US2098272A (en) * 1935-03-25 1937-11-09 Benson Simon Therapeutic apparatus

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2055128A (en) * 1933-11-01 1936-09-22 Taylor Instrument Co Apparatus and method for enhancing blood circulation
US2098272A (en) * 1935-03-25 1937-11-09 Benson Simon Therapeutic apparatus

Cited By (90)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4269175A (en) * 1977-06-06 1981-05-26 Dillon Richard S Promoting circulation of blood
US4738249A (en) * 1985-03-01 1988-04-19 The Procter & Gamble Company Method and apparatus for augmenting blood circulation
US20030032904A1 (en) * 2000-01-18 2003-02-13 Norbert Egger Fitness device in the form of a garment
US20050070405A1 (en) * 2001-10-02 2005-03-31 Norbert Egger Fitness device
US20030125649A1 (en) * 2001-10-31 2003-07-03 Mcintosh Laura Janet Method and system apparatus using temperature and pressure for treating medical disorders
US20030125646A1 (en) * 2001-12-29 2003-07-03 Whitlock Russell Ward Device and method for relieving pain
US20030216672A1 (en) * 2002-05-15 2003-11-20 The Research Foundation Of State University Of New York System and method for healing skin injuries
US20070260110A1 (en) * 2002-08-22 2007-11-08 Koenig J F Noninvasive angioplasty using momentary vacuum therapy
US8287474B1 (en) * 2002-08-22 2012-10-16 Koenig J Frank Method and apparatus for noninvasively increasing whole body blood flow and noninvasive physical exercise of limbs from the outside and from within the limb to treat diseases throughout the body
US7513879B2 (en) * 2002-08-22 2009-04-07 Koenig J Frank Noninvasive angioplasty using momentary vacuum therapy
US7846141B2 (en) 2002-09-03 2010-12-07 Bluesky Medical Group Incorporated Reduced pressure treatment system
US10265445B2 (en) 2002-09-03 2019-04-23 Smith & Nephew, Inc. Reduced pressure treatment system
US11298454B2 (en) 2002-09-03 2022-04-12 Smith & Nephew, Inc. Reduced pressure treatment system
US8628505B2 (en) 2002-09-03 2014-01-14 Bluesky Medical Group Incorporated Reduced pressure treatment system
US11376356B2 (en) 2002-09-03 2022-07-05 Smith & Nephew, Inc. Reduced pressure treatment system
US9211365B2 (en) 2002-09-03 2015-12-15 Bluesky Medical Group, Inc. Reduced pressure treatment system
US8545464B2 (en) 2002-09-03 2013-10-01 Bluesky Medical Group Incorporated Reduced pressure treatment system
US8062273B2 (en) 2002-09-03 2011-11-22 Bluesky Medical Group Incorporated Reduced pressure treatment system
US9844473B2 (en) 2002-10-28 2017-12-19 Smith & Nephew Plc Apparatus for aspirating, irrigating and cleansing wounds
US10278869B2 (en) 2002-10-28 2019-05-07 Smith & Nephew Plc Apparatus for aspirating, irrigating and cleansing wounds
US9205001B2 (en) 2002-10-28 2015-12-08 Smith & Nephew Plc Apparatus for aspirating, irrigating and cleansing wounds
US10842678B2 (en) 2002-10-28 2020-11-24 Smith & Nephew Plc Apparatus for aspirating, irrigating and cleansing wounds
US8834451B2 (en) 2002-10-28 2014-09-16 Smith & Nephew Plc In-situ wound cleansing apparatus
US9844474B2 (en) 2002-10-28 2017-12-19 Smith & Nephew Plc Apparatus for aspirating, irrigating and cleansing wounds
US8398614B2 (en) 2002-10-28 2013-03-19 Smith & Nephew Plc Apparatus for aspirating, irrigating and cleansing wounds
US7833180B2 (en) * 2002-12-31 2010-11-16 Otivio As Device for applying a pulsating pressure to a local region of the body and the applications thereof
US8361001B2 (en) * 2002-12-31 2013-01-29 Otivio As Device for applying a pulsating pressure to a local region of the body and the applications thereof
US8021314B2 (en) * 2002-12-31 2011-09-20 Otivio As Device for applying a pulsating pressure to a local region of the body and the applications thereof
US8821422B2 (en) 2002-12-31 2014-09-02 Otivio As Device for applying a pulsating pressure to a local region of the body and applications thereof
US20090036959A1 (en) * 2002-12-31 2009-02-05 Thermanor As Device for applying a pulsating pressure to a local region of the body and the applications thereof
US20110301510A1 (en) * 2002-12-31 2011-12-08 Otivio As Device for applying a pulsating pressure to a local region of the body and the applications thereof
US7833179B2 (en) * 2002-12-31 2010-11-16 Otivio As Device for applying a pulsating pressure to a local region of the body and applications thereof
US20110021960A1 (en) * 2002-12-31 2011-01-27 Otivio As Device for applying a pulsating pressure to a local region of the body and the applications thereof
US20050027218A1 (en) * 2002-12-31 2005-02-03 Marius Filtvedt Device for applying a pulsating pressure to a local region of the body and applications thereof
US9452248B2 (en) 2003-10-28 2016-09-27 Smith & Nephew Plc Wound cleansing apparatus in-situ
US9289542B2 (en) 2003-10-28 2016-03-22 Smith & Nephew Plc Wound cleansing apparatus
US8569566B2 (en) 2003-10-28 2013-10-29 Smith & Nephew, Plc Wound cleansing apparatus in-situ
US9616208B2 (en) 2003-10-28 2017-04-11 Smith & Nephew Plc Wound cleansing apparatus
US8926592B2 (en) 2003-10-28 2015-01-06 Smith & Nephew Plc Wound cleansing apparatus with heat
US9446178B2 (en) 2003-10-28 2016-09-20 Smith & Nephew Plc Wound cleansing apparatus in-situ
US20050148913A1 (en) * 2004-01-02 2005-07-07 Weston Richard S. Reduced pressure wound treatment appliance
US7128735B2 (en) 2004-01-02 2006-10-31 Richard Scott Weston Reduced pressure wound treatment appliance
US8100887B2 (en) 2004-03-09 2012-01-24 Bluesky Medical Group Incorporated Enclosure-based reduced pressure treatment system
US8708998B2 (en) 2004-03-09 2014-04-29 Bluesky Medical Group, Inc. Enclosure-based reduced pressure treatment system
US20100305549A1 (en) * 2004-04-05 2010-12-02 Bluesky Medical Group Incorporated Reduced pressure wound treatment system
US10363346B2 (en) 2004-04-05 2019-07-30 Smith & Nephew, Inc. Flexible reduced pressure treatment appliance
US9198801B2 (en) 2004-04-05 2015-12-01 Bluesky Medical Group, Inc. Flexible reduced pressure treatment appliance
US8540699B2 (en) 2004-04-05 2013-09-24 Bluesky Medical Group Incorporated Reduced pressure wound treatment system
US8449509B2 (en) 2004-04-05 2013-05-28 Bluesky Medical Group Incorporated Flexible reduced pressure treatment appliance
US11730874B2 (en) 2004-04-05 2023-08-22 Smith & Nephew, Inc. Reduced pressure treatment appliance
US10842919B2 (en) 2004-04-05 2020-11-24 Smith & Nephew, Inc. Reduced pressure treatment system
US7708724B2 (en) 2004-04-05 2010-05-04 Blue Sky Medical Group Incorporated Reduced pressure wound cupping treatment system
US10350339B2 (en) 2004-04-05 2019-07-16 Smith & Nephew, Inc. Flexible reduced pressure treatment appliance
US9492326B2 (en) 2004-04-05 2016-11-15 Bluesky Medical Group Incorporated Reduced pressure wound treatment system
US7909805B2 (en) 2004-04-05 2011-03-22 Bluesky Medical Group Incorporated Flexible reduced pressure treatment appliance
US10105471B2 (en) 2004-04-05 2018-10-23 Smith & Nephew, Inc. Reduced pressure treatment system
US7776028B2 (en) 2004-04-05 2010-08-17 Bluesky Medical Group Incorporated Adjustable overlay reduced pressure wound treatment system
US10058642B2 (en) 2004-04-05 2018-08-28 Bluesky Medical Group Incorporated Reduced pressure treatment system
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US10207035B2 (en) 2004-05-21 2019-02-19 Smith & Nephew, Inc. Flexible reduced pressure treatment appliance
US20050261615A1 (en) * 2004-05-21 2005-11-24 Richard Scott Weston Hypobaric chamber treatment system
US7998125B2 (en) * 2004-05-21 2011-08-16 Bluesky Medical Group Incorporated Hypobaric chamber treatment system
US9925313B2 (en) 2004-05-21 2018-03-27 Smith & Nephew, Inc. Flexible reduced pressure treatment appliance
US7857775B2 (en) * 2005-03-15 2010-12-28 Syneron Medical Ltd. Method for soft tissue treatment
US20060211958A1 (en) * 2005-03-15 2006-09-21 Syneron Medical Ltd. Method and device for soft tissue treatment
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US12257207B2 (en) 2017-09-29 2025-03-25 Otivio As Medical pressure therapy device and components thereof
US10940075B2 (en) 2017-09-29 2021-03-09 Otivio As Medical pressure therapy device and components thereof
US11110021B2 (en) 2017-09-29 2021-09-07 Otivio As Medical pressure therapy device and components thereof
AU2018343331B2 (en) * 2017-09-29 2024-02-15 Otivio As Medical pressure therapy device and components thereof
US11259985B2 (en) 2017-09-29 2022-03-01 Otivio As Medical pressure therapy device and components thereof
WO2019064288A1 (en) * 2017-09-29 2019-04-04 Otivio As MEDICAL DEVICE FOR PRESSURE THERAPY AND ITS ELEMENTS
USD900996S1 (en) 2017-10-16 2020-11-03 Otivio As Pressure chamber
USD901670S1 (en) 2018-08-10 2020-11-10 Otivio As Pressure control unit
USD889634S1 (en) 2018-08-10 2020-07-07 Otivio As Pressure control unit
US20230023986A1 (en) * 2019-12-31 2023-01-26 Nuwelilis, Inc. Venous blood flow stimulator for extracorporeal therapy
US11793709B2 (en) * 2019-12-31 2023-10-24 Nuwellis, Inc. Venous blood flow stimulator for extracorporeal therapy
US12011416B2 (en) 2019-12-31 2024-06-18 Nuwellis, Inc. Venous blood flow stimulator for extracorporeal therapy
US20230190570A1 (en) * 2020-06-22 2023-06-22 Otivio As Methods for treating spasticity using anti-spasmodic compositions and negative pressure therapy
JP2023530769A (ja) * 2020-06-22 2023-07-19 オティビオ・エーエス 鎮痙組成物および陰圧療法を用いて痙縮を治療するための方法
US20210393472A1 (en) * 2020-06-22 2021-12-23 Otivio As Pressure therapy methods and devices for treating spasticity
JP7586521B2 (ja) 2020-06-22 2024-11-19 オティビオ・エーエス 鎮痙組成物および陰圧療法を用いて痙縮を治療するための方法

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CH467618A (de) 1969-01-31
GB1172077A (en) 1969-11-26
FR1499586A (fr) 1967-10-27

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