US3628891A - Method for the minimization of the effects of pulsations in intermittent pumping systems - Google Patents

Method for the minimization of the effects of pulsations in intermittent pumping systems Download PDF

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US3628891A
US3628891A US71777A US3628891DA US3628891A US 3628891 A US3628891 A US 3628891A US 71777 A US71777 A US 71777A US 3628891D A US3628891D A US 3628891DA US 3628891 A US3628891 A US 3628891A
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pump
fluid
pulsations
inlet means
fluid stream
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Jack Isreeli
Aaron Kassel
Robert Dannewitz
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Technicon Corp
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Technicon Corp
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    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
    • F04B43/00—Machines, pumps, or pumping installations having flexible working members
    • F04B43/12—Machines, pumps, or pumping installations having flexible working members having peristaltic action
    • F04B43/1223—Machines, pumps, or pumping installations having flexible working members having peristaltic action the actuating elements, e.g. rollers, moving in a straight line during squeezing
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
    • F04B11/00—Equalisation of pulses, e.g. by use of air vessels; Counteracting cavitation
    • F04B11/005—Equalisation of pulses, e.g. by use of air vessels; Counteracting cavitation using two or more pumping pistons
    • F04B11/0075—Equalisation of pulses, e.g. by use of air vessels; Counteracting cavitation using two or more pumping pistons connected in series
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/08—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a stream of discrete samples flowing along a tube system, e.g. flow injection analysis

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  • Tedesco ABSTRACT New and improved method for minimizing the effects of pulsations which occur during the operation of intermittent pumping systems is provided and, as disclosed, is applied to a peristaltic pump which is utilized in a fluid sample supply, treatment and analysis system and comprises the minimization of the effects of the pulsation which occurs each time a pump roller occludes the compressible pump tube, and the minimization of the effects of the pulsation which occurs each time a pump roller discontinues the occlusion of the compressible pump tube.
  • any intermittent pumping system in the nature, for example, of a peristaltic pumping system or a pressure-pumped exchange valve and pilot fluid pumping system, it may be understood that intermittent pulsations in the provided flow rate will, of necessity, occur.
  • treatment and analysis means of the nature disclosed in U.S. Pat. No. 3,241,432 issued Mar.
  • treatment and analysis means which are operable, to significant advantage, at substantially reduced sample portion sampling times and with substantially reduced sample portion flow rates and volumes, however, it may be understood that a method must be provided to minimize the efiects of such pulsations, or that unacceptable variations in the essential sample portion phasing and in the essential sample portion-sample treatment fluid proportioning will result.
  • Another object of this invention is to provide method as above which may be applied to said intermittent pumping systems without structural modification of the latter.
  • a further object of this invention is the provision of method as above which is particularly adaptable for use in intermittent pumping systems which form part of automatically operable, substantially constant flow rate fluid sample supply, treatment and analysis means.
  • the method of the invention is applied to a peristaltic pump which is operable, in a fluid sample analysis system, through the progressive occlusion of a compressible pump tube by a plurality of substantially equally spaced pump rollers to pump fluid sample portions in a precisely phased successive stream thereof from fluid sample supply means to fluid sample treatment and analysis means.
  • a separating fluid portion which includes an air segment is provided in said fluid sample portion stream intermediate adjacent fluid sample portions.
  • a pulsation in the pump delivery rate occurs each time a said pump roller occludes said pump tube, and each time a said pump roller discontinues the occlusion of said pump tube.
  • Said fluid sample portions are supplied to said compressible pump tube by the aspiration thereof from sample container means through the inlet end of a connected sample offtake device which functions as pump inlet means, and each of said fluid sample portions is treated downstream of said compressible tube pump by the mixture thereof in precisely determined proportion with a sample treatment fluid through the merger of a stream of the latter with said sample portion stream.
  • the method of the invention minimizes the effects of the first-mentioned pulsation by insuring, through proper control of the operational timing of said pump rollers and said pump inlet means flow path length determination, that said offtake device inlet end is not exposed to the air at the time said pulsation arrives thereat to thus insure the aspiration of the separating fluid portion air segment of the required volume.
  • the method of the invention minimizes the effects of the second-mentioned pulsation by insuring, through proper determination of the flow path length between said pump roller as the latter discontinues said occluding contact, and the point at which said sample portion stream merges with said sample treatment fluid stream, that one of said separating fluid portion air segments is disposed at said merger point at the time of the arrival thereat of said pulsation to thus minimize the extent of the change, if any caused thereby in said sample portion-sample treatment fluid proportion and, in any event, restrict the same to the beginning or end part of each of said sample portions to render the same incapable of modifying the recorded sample portion analysis results.
  • FIG. 1 is a flow diagram illustrating the application of the method of the invention to the operation of peristaltic pump means in a fluid sample supply, treatment and analysis system, and depicts said pump means in a first operational position thereof;
  • FIG. 2 is a flow diagram depicting the peristaltic pump of FIG. 1 in a second operational position thereof;
  • FIG. 3 is a graph depicting pump delivery plotted against time and illustrates the pump pulsations of interest
  • FIG. 4 is a graph depicting treated sample portion optical density plotted against time and illustrates the minimization of the effects of one of the pulsations of FIG. 3;
  • FIG. 5 is a flow diagram illustrating fluid flow through the peristaltic pump of FIG. 1 when the same is used in a somewhat differently operable fluid sample supply, treatment and analysis system.
  • FIG. I new and improved sample supply system constructed and .operative in accordance with the teachings of this invention are indicated generally at 8, and comprise compressible tube pump means as indicated generally at 10 and operatively associated sample supply means as indicated generally at 12.
  • the sample supply means 12 may, for example, take the form of those shown and described in U.S. Pat. No. 3,134,263 issued May 26, 1964 to Edward B. M. DeJong, and comprise a turntable 14 upon which is disposed a generally circular array of sample containers 16.
  • a sample offtake device is indicated generally at 18 and comprises a sample offtake tube 20 and offtake tube operating-means 22, respectively.
  • a wash liquid receptacle 24 is disposed as shown adjacent the turntable 14, while sample supply device drive means are indicated at 26 and are operative to drive each of the turntable l4 and the sample offtake device 18 as indicated by the dashed lines extending therebetween.
  • the turntable 14 is intermittently rotated, or indexed, to present each of the sample containers 16 in turn to the sample offtake device 18, while the latter is operated to immerse the inlet end or offtake tube 20 in a thusly presented sample container for a predetermined period of time to aspirate (as described in detail hereinbelow) a measured volume of the sample therefrom, to then transfer the said offtake tube inlet end through the ambient air for immersion in the wash liquid receptacle for a predetermined period of time to thus aspirate a measured volume of ambient air followed by a measured volume of said wash liquid, and to then again transfer the said offtake tube inlet and through the ambient air for immersion in the next-presented sample container 16 for a predetermined period of time to thus aspirate aNother measured volume of ambient air and commence the aspiration of a measured volume of the sample from said next-presented sample container.
  • aspirate as described in detail hereinbelow
  • a stream S consisting of successive ones of portions of said samples of substantially equal predetermined volume as spaced, in each instance, by a segment of air A, a segment of wash liquid W and a segment of air A, respectively, will be supplied to the offtake tube 20.
  • the compressible tube or peristaltic pump may, for example, take the general form of that shown and described in U.S. Pat. No. 3,227,091 issued Jan. 4, 1966 to Jack lsl'eeli et al., and comprises spaced pump tube mounting blocks as indicated at 32 and 34.
  • a compressible pump tube 36 which is made from any suitably resilient material of appropriate strength characteristics in the nature, for example, of silicone rubber, is extended as shown between the said pump tube mounting blocks and affixed thereto by means of the placement of said pump tube in nonillustrated aligned mounting grooves formed in said pump tube mounting blocks, and the attachment of collar elements 38 and 40, as shown to opposite end portions of said pump tube, all in a manner made clear in said U.S. Pat. No. 3,2 27,091.
  • the inlet end of the compressible pump tube 36 is connected as indicated at 41 to the outlet end of the sample ofitake tube 20.
  • a pump roller assembly is indicated generally at 42 and comprises an endless chain 44 which is disposed as shown around a chain guide member 46 and is driveable therearound in the indicated clockwise direction through the driven rotation of a chain drive sprocket 48.
  • a plurality of substantially equally spaced pump rollers 50A, 50B, 50C and 50D are rotatably mounted in any convenient manner on endless chain 44 as shown, whereby may be understood that those of said rollers which are, at any given point in time, mounted on the upper throw of the endless chain 44 will be movable with the latter in the direction from left to right as seen in FIG. 1.
  • endless chain 44 As shown, however may be understood that those of said rollers which are, at any given point in time, mounted on the upper throw of the endless chain 44 will be movable with the latter in the direction from left to right as seen in FIG. 1.
  • only one chain and drive sprocket are depicted, it may be understood that at least two of the same would be provided in spaced, general alignment, and that the respective pump rollers would, of course, extend therebetween.
  • a pump platen is indicated at 52 and may be understood to be movable, as by pivotal movement, from a nonillustrated open" position thereof to the depicted closed" position thereof wherein the pump tube 36 will be disposed as shown in firm contact with the undersurface of said platen, and will be forced to conform with the configuration of the bottom surface 54 of said groove and pressed thereby against the respective relevant rollers 50, all again as described in detail in said U.S. Pat. No. 3,227,091.
  • Pump drive means which may, for example, take the form of any suitable electric motor, are indicated at 56, and are operatively connected, as indicated by the dashed line, to the chain drive sprocket 48 to drivingly rotate the latter.
  • the operation of sample supply device drive means 26 is synchronized with the operation of the pump drive means 56, and this may be understood to be indicated in the drawings by the extension of lead 58 therebetween.
  • a single drive means in the nature of a suitable electric drive motor may be provided and operatively connected, as by conventional mechanical connecting means, to both the pump 10 and the sample supply device 12 to drive the same in the described synchronized manner.
  • sample portions which constitute this sample portion stream will be spaced, each from the other, by a separating fluid portion which, in this instance, will be constituted as described by a segment of air A1, a slug of wash liquid W, and a segment of air A2, arranged in that order.
  • Sample treatment fluid supply means are indicated generally at 66 and may be understood to function to supply a sample treatment fluid to the sample portion stream supply conduit 62 for mixture therewithin in carefully predetermined proportion with each of said sample portions being pumped therethrougli.
  • the sample treatment fluid supply means 66 may, for example, take the general form of those shown and described in the copending application for U.S. Pat. Ser. No. 120,153 of Edward B. M. DeJong filed Mar. 2, 1971 and assigned to the assignee hereof (continuation in part of U.S. Pat. Ser. No. 712,431 filed Mar. 12, 1968, now abandoned) and, as such, will comprise a tank 68 of air at suitable pressure, as, for example, 2,200 psi. connected as shown by conduit 70 through suitable pressure regulator means 72 to a T-fitting 74 to maintain the latter at substantially constant pressure in the order, for example, of 66.8 cm. Hg.
  • the sample treatment fluid of interest may, for example, be constituted by a color-producing reagent liquid which, when mixed with said sample portions, will enable the respective colorimetric quantitative analyses thereof with respect to a predetermined blood sample constituent, all as described in greater detail in said U.S. Pat. No. 3,241,432.
  • a conduit 78 extends as shown from outlet of the Tfitting 74 through the screw-on cover 80 of a reagent liquid flask 82 to thus pressurize the interior of the latter at said substantially constant pressure.
  • An outlet conduit 84 connects the interior of the flask 82 to the inlet of a precisely calibrated high flow resistance coil 86, the outlet of which is in turn connected as shown by reagent liquid supply conduit 88 to one inlet of a T- fitting 90 which is interposed in the sample portion stream supply conduit 62.
  • the other outlet of the T-fitting 74 is connected as shown by conduit 92 to the inlet of a precisely calibrated high flow resistance coil 94, and the outlet of the latter is connected by air supply conduit 96 to a T-fitting 98 which is interposed as shown in the reagent liquid supply conduit 88.
  • the high flow resistance coil 86 will preferably be disposed in a temperature control bath as indicated in dashed lines at 99 to maintain the temperature thereof at a suitable, substantially constant level as, for example, 37 C. to in turn maintain the temperature, and accordingly the viscosity and flow rate of the reagent liquid flowing therethrough at substantially constant, predetermined values.
  • a suitable, substantially constant level as, for example, 37 C. to in turn maintain the temperature, and accordingly the viscosity and flow rate of the reagent liquid flowing therethrough at substantially constant, predetermined values.
  • the respective reagent liquid flask 82 and portions at least of the respective conduits 84 and 88 may also be immersed in said temperature control bath.
  • the pressurized air from tank 68 will be effective to pump the reagent liquid R from the flask 82 at a substantially constant, predetermined flow rate through the high flow resistance coil 86 and therefrom, through reagent liquid supply conduit 88, to the sample stream supply conduit 62 for merger therewithin with the sample portion stream S flowing through the latter.
  • the pressurized air from tank 68 will be flowed, again at substantially constant, predetermined flow rate, through high flow resistance coil 94 and therefrom through air supply conduit 96 for merger with the reagent liquid stream flowing in reagent supply conduit 88 to air segment the same as shown to promote proper mixing thereof with the sample stream S upon the merger thereof as discussed hereinabove.
  • the graph 100 represents proportioning pump delivery as plotted against time for the travel of one of the compressible pump rollers 50 through one tube compressing cycle thereof, it may be understood that pulsations as indicated at 102 and 104 will respectively occur in said pump delivery rate as the said pump roller makes contact with and occludes the pump tube 36 at the commencement of the pumping cycle of interest, and as the said pump roller terminates the occluding contact thereof.
  • Sample treatment and analysis means of the nature discussed may be understood to be satisfactorily operable only at substantially constant flow rate, and to further depend for satisfactory constant flow rate, and to precise proportioning between each of the sample portions and the reagent liquid which is merged therewith, and upon the substantially precise maintenance of a predetermined phase relationship between the respective sample portions. Accordingly, it becomes essential that the effects of pulsations as indicated at 102 and 104 in FIG. 3 upon such flow rate, proportioning and sample portion phase. relationship be minimized, if not altogether removed.
  • the pulsation 102 which occurs as set forth hereinabove as a pump roller commences the occlusion of the compressible pump tube 36, it may be understood that this point in the operation of the compressible tube pump 10 as illustrated in FIG. 1 wherein the pump roller 50B is depicted as commencing the occlusion of the compressible pump tube 36.
  • the pulsation 102 of FIG. 3 will, of course, travel in both directions from the point of roller-pump tube contact through the sample portion stream S then flowing in said pump tube. The travel of this pulsation in the direction from left to right as seen in FIG. 1, or, that is to say, the downstream direction, will be terminated at the roller 50A since the latter is, at this point in time, fully occluding the compressible pump tube 36 to thereby render substantially impossible further travel of said pulsation in this direction.
  • the amount of airaspirated is simply reduced but is still adequate to form aleading air segment as indicated at A1 in FIG. 1 of at least the minimum volume required to occlude the nonuniform tube 36, it may be understood that the said air segment Al will be smaller than and thus of nonuniform volume with regard to the trailing' air segment as indicated at A2 whereby the essential sample portion phase relationship may be modified to obvious disadvantage.
  • the amount of air aspirated is reduced to the extent that insufficient air is provided for the formation of an air segment A of minimum volume to fully occlude the pump tube 36- thereby resulting only in the formation of a suspended air bubbleor if no air is aspirated at all, it is believed. clear that the essential inter sample portion cleansing and sample portion separating functions of the air segment A which was to have been formed will also be eliminated along with the phase relationship destruction as discussed hereinabove.
  • the sample offtake tube 20 will be arranged as illustrated so that the inlet end thereof will be immersed in a sample container 16 generally intermediate the aspiration of a sample portion at the time of the arrival of the pulsation 102 at said inlet end, with resultant substantial absorption of said pulsation to render the efiects of the latter substantially undetectable during the steady state flow rate portion of sample stream flow.
  • the sample offtake tube 20 may be arranged so that the inlet end thereof will be immersed in the wash liquid receptacle 24 at the time of arrival of the pulsation 102 thereat although this may, of course, prove unacceptable in instances as discussed hereinabove wherein the total time for wash liquid slug aspiration is so short in relation to the duration of the pulsation 102 that the former cannot accommodate the latter and still provide for the aspiration of a wash liquid slug W of suitable volume.
  • the length of the fluid flow path through the compressible pump tube 36 from the point thereon whereat the respective pump rollers discontinue occluding contact therewith as illustrated by the position of pump roller 50A in FIG. 1, and the T-fitting 90 is precisely predetermined in accordance with the fluid flow rate therethrough to insure that the arrival of the pulsation 104 at the said T-llitting will occur substantially concomitantly with the arrival of an air segment A1 or A2 thereat.
  • nonillustrated sample treatment and analysis means of the type discussed include colorimeter means through which the appropriately treated sample portions which then constitute the sample portion stream S are successively flowed, and operatively connected null balance-type strip chart recorder means which provide a record of the colorimetric analysis of said sample portion, all as described in detail in said US. Pat. No. 3,241,432-FIG.
  • sample portion supply means 12 could be modified by the deletion of the wash liquid reservoir 24 and the arrangement of the sample offtake means 18 to aspirate repeated small volumes of each of the samples as spaced, each from the other, by a small segment of air A, prior to the aspiration of the main body of the sample portion-with said small sample portion volumes functioning in the manner of the wash liquid in conjunction with said air segments as the separating fluid portion to remove the residue, if any, of the preceding sample portion and inhibit the contamination of the succeeding sample portion therebyand that the teachings of the invention should be equally applicable to such system.
  • FIG. which illustrates the sample portion stream which would result from such operation
  • the respective turntable 14, sample offtake tubes 20, proportioning pump and T-lfitting 90 would respectively again be arranged as described in detail hereinabove to insure that the offtake tube inlet end would be immersed in a sample container concomitantly with the arrival thereat of the pulsation 102 for each of the pump rollers 50, and to insure that the arrival of the pulsation 104 for each of the pump rollers at the T-fitting 90 would occur substantially concomitantly with the arrival of one of said air segments A thereat.
  • the apparatus of the invention are arranged as illustrated and described so that each of the pump rollers makes occluding contact with the compressible pump tube 36 generally intermediate a sample portion as shown as at S1, S2, S3, etc., rather than at a separating fluid portion, to thus prevent the breaking up of the respective air segments A by such occluding contact into air bubbles which may not reform as air segments and thus would no longer function to occlude the compressible pump tube 36 to very significant disadvantage as discussed in detail hereinabove.
  • the proportioning pump 10 may alternatively be arranged to operate with one such pump tube occluding contact per two or more sample portions to, in any event, minimize the number of pump roller-compressible pump tube contacts per sample portion and thus minimize compressible pump tube wear as should be obvious.
  • said pump comprises a progressively occludable pump tube and said method further comprises, the steps of, operating said pumping system to provide separating fluid portions of the minimum volume required to occlude said pump tube.
  • said pump comprises a progressively occludable pump tube and said method further comprises, the steps of, operating said pump and said pump inlet means to provide air segments of the minimum volume required to occlude said pump tube.
  • said pump comprises a progressively occludablepump tube and said method further comprises, the steps of, operating said pump and said pump inlet means to provide air segments of the minimum volume required to occlude said pump tube.
  • the steps of arranging said fluid stream flow paths comprise the establishment of the length of said first fluid stream flow path between the outlet side of said pumping means and said flow path juncture in accordance with the flow rate through said first fluid stream flow path to provide for said substantially concomitant pulsations and separating fluid portions arrivals at said flow path juncture.
  • said pump comprises a progressively occludable pump tube and said method further comprises, the steps of, operating said pumping system to provide separating fluid portions of the minimum volume required to occlude said pump tube.
  • said pump comprises a progressively occludable pump tube and said method further comprises, the steps of, operating said pumping system to provide separating fluid portions of the minimum volume required to occlude said pumptube.
  • the steps of arranging said fluid stream flow paths comprise the establishment of the length of said first fluid stream flow path between the outlet side of said pumping means and said flow path juncture in accordance with the flow rate through said first fluid stream flow path to provide for said substantially concomitant pulsations and separating fluids portions arrivals at said flow path juncture.
  • the steps of arranging said fluid stream flow paths comprise the establishment of the length of said first fluid stream flow path between the outlet side of said pumping means and said flow path juncture in accordance with the flow rate through said first fluid stream flow path to provide for said substantially concomitant pulsations and separating fluid portions arrivals at said flow path juncture.
  • said pump comprises a progressively occludable pump tube and said method further comprises, the steps of, operating said pump and said pump inlet means to provide air segments of the minimum volume required to occlude said pump tube.
  • said pump comprises a progressively occludable pump tube and said method further comprises, the steps of, operating said pump and said pump inlet means to provide air segments of the minimum volume required to occlude said pump tube.
  • the steps of arranging said fluid stream flow paths comprise the establishment of the length of said first fluid stream flow path between the outlet side of said pumping means and said flow path juncture in accordance with the flow rate through said first fluid stream flow path to provide for said substantially concomitant pulsations and separating fluid portions arrivals at said flow path juncture.

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US71777A 1970-09-14 1970-09-14 Method for the minimization of the effects of pulsations in intermittent pumping systems Expired - Lifetime US3628891A (en)

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US (1) US3628891A (de)
AU (1) AU445535B2 (de)
BE (1) BE771322A (de)
CA (1) CA938194A (de)
CH (1) CH534304A (de)
DE (1) DE2144122C3 (de)
FR (1) FR2107509A5 (de)
GB (1) GB1339807A (de)
IT (1) IT938777B (de)
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Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3758239A (en) * 1970-12-23 1973-09-11 Ceskoslovenska Akademie Ved Controlled peristaltic pump
US4100797A (en) * 1977-01-17 1978-07-18 Technicon Instruments Corporation Non-invasive method and apparatus for instantaneous flow measurement of a segmented fluid stream
US4218197A (en) * 1978-07-06 1980-08-19 Beckman Instruments, Inc. Combined peristaltic pump and valve flow controller
FR2491624A1 (fr) * 1980-10-06 1982-04-09 Technicon Instr Procede pour le fonctionnement d'un appareil d'analyse automatique
FR2581133A1 (fr) * 1985-04-30 1986-10-31 Vidal Lucien Pompe peristaltique lineaire pour vehiculer du beton ou autre
WO1989000698A1 (en) * 1985-11-08 1989-01-26 Wessex Instrumentation Ltd. Continuous flow analysis
US20060228240A1 (en) * 2005-03-30 2006-10-12 Lancer Partnership, Ltd. Method and apparatus for a linear peristaltic pump
US20070258829A1 (en) * 2006-04-21 2007-11-08 Bredel Hose Pumps B.V. Peristaltic pump
US20100135824A1 (en) * 2008-11-05 2010-06-03 Roche Diagnostics Operations, Inc. Process for Peristaltic Pump Control
US20110060284A1 (en) * 2009-09-10 2011-03-10 Tyco Healthcare Group Lp Compact peristaltic medical pump
EP4239341A4 (de) * 2020-10-30 2024-08-21 Hitachi High-Tech Corporation Automatische analysevorrichtung

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE8810455U1 (de) * 1988-08-18 1988-09-29 Hoechst Ag, 6230 Frankfurt Vorrichtung zum Dämpfen von stoßweise fördernden Pumpen

Citations (2)

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Publication number Priority date Publication date Assignee Title
US3134263A (en) * 1961-10-20 1964-05-26 Technicon Instr Sample-supply device for automatic analysis apparatus
US3588281A (en) * 1969-07-24 1971-06-28 Technicon Corp Method and apparatus for the pumping of fluids at substantially constant flow rate

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3134263A (en) * 1961-10-20 1964-05-26 Technicon Instr Sample-supply device for automatic analysis apparatus
US3588281A (en) * 1969-07-24 1971-06-28 Technicon Corp Method and apparatus for the pumping of fluids at substantially constant flow rate

Cited By (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3758239A (en) * 1970-12-23 1973-09-11 Ceskoslovenska Akademie Ved Controlled peristaltic pump
US4100797A (en) * 1977-01-17 1978-07-18 Technicon Instruments Corporation Non-invasive method and apparatus for instantaneous flow measurement of a segmented fluid stream
US4218197A (en) * 1978-07-06 1980-08-19 Beckman Instruments, Inc. Combined peristaltic pump and valve flow controller
FR2491624A1 (fr) * 1980-10-06 1982-04-09 Technicon Instr Procede pour le fonctionnement d'un appareil d'analyse automatique
FR2581133A1 (fr) * 1985-04-30 1986-10-31 Vidal Lucien Pompe peristaltique lineaire pour vehiculer du beton ou autre
EP0201389A1 (de) * 1985-04-30 1986-11-12 Lucien René Vidal Lineare peristaltische Pumpe zum Transportieren von Beton oder anderen Materialien
US4735553A (en) * 1985-04-30 1988-04-05 Lucien Vidal Straight peristaltic pump for conveying concrete or the like
WO1989000698A1 (en) * 1985-11-08 1989-01-26 Wessex Instrumentation Ltd. Continuous flow analysis
US20060228240A1 (en) * 2005-03-30 2006-10-12 Lancer Partnership, Ltd. Method and apparatus for a linear peristaltic pump
US20070258829A1 (en) * 2006-04-21 2007-11-08 Bredel Hose Pumps B.V. Peristaltic pump
US8157547B2 (en) * 2006-04-21 2012-04-17 Bredel Hose Pumps B.V. Peristaltic pump with flow control
US20100135824A1 (en) * 2008-11-05 2010-06-03 Roche Diagnostics Operations, Inc. Process for Peristaltic Pump Control
US20110060284A1 (en) * 2009-09-10 2011-03-10 Tyco Healthcare Group Lp Compact peristaltic medical pump
US8241018B2 (en) 2009-09-10 2012-08-14 Tyco Healthcare Group Lp Compact peristaltic medical pump
US8882481B2 (en) 2009-09-10 2014-11-11 Covidien Lp Compact peristaltic medical pump
EP4239341A4 (de) * 2020-10-30 2024-08-21 Hitachi High-Tech Corporation Automatische analysevorrichtung

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SE371863B (de) 1974-12-02
BE771322A (fr) 1972-02-14
NL7111946A (de) 1972-03-16
AU445535B2 (en) 1974-02-21
DE2144122A1 (de) 1972-03-23
DE2144122C3 (de) 1974-06-20
FR2107509A5 (de) 1972-05-05
CH534304A (de) 1973-02-28
AU3253471A (en) 1973-02-22
DE2144122B2 (de) 1973-09-27
IT938777B (it) 1973-02-10
GB1339807A (en) 1973-12-05
CA938194A (en) 1973-12-11

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