US3677246A - Hypodermic syringe - Google Patents
Hypodermic syringe Download PDFInfo
- Publication number
- US3677246A US3677246A US116108A US3677246DA US3677246A US 3677246 A US3677246 A US 3677246A US 116108 A US116108 A US 116108A US 3677246D A US3677246D A US 3677246DA US 3677246 A US3677246 A US 3677246A
- Authority
- US
- United States
- Prior art keywords
- injection
- housing
- container
- cylinder
- hypodermic syringe
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 238000002347 injection Methods 0.000 claims abstract description 96
- 239000007924 injection Substances 0.000 claims abstract description 96
- 239000000243 solution Substances 0.000 claims abstract description 32
- 230000000694 effects Effects 0.000 claims description 4
- 238000003780 insertion Methods 0.000 claims description 2
- 230000037431 insertion Effects 0.000 claims description 2
- 239000003708 ampul Substances 0.000 abstract description 15
- NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 abstract description 6
- 102000004877 Insulin Human genes 0.000 abstract description 3
- 108090001061 Insulin Proteins 0.000 abstract description 3
- 229940125396 insulin Drugs 0.000 abstract description 3
- 241001465754 Metazoa Species 0.000 description 3
- 239000007788 liquid Substances 0.000 description 3
- 238000010276 construction Methods 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 230000006835 compression Effects 0.000 description 1
- 238000007906 compression Methods 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 230000035515 penetration Effects 0.000 description 1
- 229920003023 plastic Polymers 0.000 description 1
- 230000000717 retained effect Effects 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
- A61M5/204—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically connected to external reservoirs for multiple refilling
Definitions
- a hypodermic syringe with a container having a supply of the injection solution from which the injection chamber of the syringe can be filled repeatedly.
- Syringes of this type typically are provided with an intermediate chamber which communicates at one side with a supply container and at the other side with the injection chamber in such a manner that, when the plunger is retracted, the injection solution is forced out of the intermediate chamber into the injection chamber while a return flow of the solution into the intermediate chamber is prevented by a oneway valve between the two chambers.
- This type of syringe however has the disadvantage of being complex in construction and is expensive to manufacture.
- the syringe of this invention is provided with an injection chamber which is adapted to serve also as a measuring chamber, the latter being connected with a supply chamber and with a pump which is associated with the supply chamber and Operable by a plunger from outside the syringe.
- Injection of the injection solution is carried out according to the present invention by releasing a main spring which first pushes the filled injection chamber forwardly to introduce the hypodermic needle and then pushes the injection piston forwardly within this chamber to inject a predetermined amount of the solution.
- the present invention provides that, before the injection piston can be pushed forwardly within the injection chamber, the injection chamber has to be pushed forwardly for a certain distance.
- hypodermic syringe of this invention While it may generally have a similar tubular cylindrical shape, it is provided with 21 preferably exchangeable container for a larger supply of an injection solution and with a device for measuring the amount of this solution which is required for an injection and that it merely requires the simple manual actuation of a plunger to pass this required amount of the solution from the supply container to the injection chamber.
- FIG. 1 is a longitudinal sectional view of a hypodermic syringe assembly embodying the invention.
- FIG. 2 is a perspective view of a pump forming a part of the syringe assembly.
- the hypodermic syringe of this invention comprises a main cylindrical outer casing or housing 1.
- an injection cylinder 2b having a chamber 2 which contains a solution of insulin for example to be injected into a human being or animal through a hypodermic needle 2f carried by the cylinder 2b and extending forwardly thereof through an opening 7a in a cap 7 on the forward end of the casing 1.
- An injection piston 2a is axially slidable within the cylinder 2b and advancement of the piston 2a in the cylinder 2b ejects a predetermined amount of the solution in the chamber 2 through the needle 2f.
- the volume of chamber 2 is variable by means of an adjustable cap nut 2c threaded on the rearward end of the cylinder 2b.
- an adjustable cap nut 2c threaded on the rearward end of the cylinder 2b.
- the syringe contains a supply container for the injection solution here shown in the form of a glass ampoule 3 which is confined in a cylindrical casing 12.
- the ampoule 3 holds a supply of the injection solution which is sufficient for several injections.
- the injection solution is forced from the ampoule 3 into the chamber 2 through the discharge tube 3a of the ampoule and a connecting passage 2g in the piston 2a by a pump 4 interposed between the forward end of the ampoule and the adjacent end of the casing 12.
- the pump 4 consists of a cup-shaped piston 4b which is mounted for reciprocation in a cup-shaped cylinder 4a and is held normally retracted by a central spring 4c. Air is admitted into the pump 4 through an air inlet duct 4d which is controlled by a check valve 4 ⁇ " and air under pressure is discharged from the pump into the ampoule through a tube 4e which preferably is in the form of a hollow needle.
- the needle-like tube 4e is adapted to pierce through the end of the ampoule 3 when the latter is introduced into the casing 12.
- a manually operable plunger 6 mounted and supported in reciprocation in the rearward ends of the casings l and 12 is movable against the ampoule 3 to push the latter against the pump 4 so as to advance the cylinder 4a on the piston 4b against the action of the spring 40 whereby to force air under pressure into the ampoule through the tube 4e. Air pressure in the ampoule 3 in turn forces solu-.
- the volume of the injection chamber 2 may be varied by adjustment of the cap nut 20 along a male screw thread on the cylinder 2b. Each complete turn or a specific part of a turn of the cap nut 20 results in a predetermined adjustment of the volume of the chamber 2 which may be indicated by a suitably graduated scale (not shown) on the nut.
- the cap nut 2c is adjustably positioned so that the person using the syringe may be sure that he will inject a desired predetermined amount of solution at each injection.
- the injection may be carried out by placing the point of the hypodermic needle against the flesh of the person or animal and releasing the locking lever 8 from the bottom 12a of the inner casing 12 by the pressure of a finger upon the outer end 8a of lever 8 in the direction of the arrow.
- the main compression spring 5 acting upon the other end wall of the inner casing 12 then shifts this casing, the ampoule 3, the injection cylinder 2b and the piston 2a bodily forwardly in the outer casing 1 until the injection casing 2b engages the cap 7.
- the needle 2f is driven into the flesh preparatory to the injection.
- a leaf spring 9 which holds the two cylinders 2b and I2 normally in fixed spaced relation.
- the spring 9 thus prevents forward movement of piston 2a in the cylinder 2b during initial advancement of the inner components of the syringe in the manner described above.
- the slide contact 9a carried by the spring 9 reaches a relatively wide place 10a in the slot 10.
- the leaf spring 9 snaps outwardly through the slot 10 and thereby releases the rear casing 12 so that it can move forwardly independently of and relative to the injection cylinder 2b. This action preferably occurs shortly before the time the injection cylinder 2b strikes the cap 7. In this connection, it
- the cap 7 is adjustable on the outer casing 1 to vary the amount of forward movement of the injection cylinder 2b and the depth of penetration of the hypodermic needle 2f.
- continued thrust of the spring 5 after release of the leaf spring 9 from the rear casing 12 and engagement of the front casing 2b with the cap 7 shoots the piston 4b forwardly in the chamber 2 to forcibly eject the contents of the chamber through the needle 2f.
- the rear casing 12 is pulled back by means of the plunger 6 until the locking lever 8 snaps into place against the front end 12a of the casing to hold the latter fully retracted and the leaf spring 9 is pressed back against the front wall 12a of the casing 12 by pressure on the key 9b to hold the two casings 2b and 12 again in fixed spaced apart relation.
- the plunger 6 can then be manipulated back and forth in the manner hereinabove described to pump another charge of injection liquid from the ampoule 3 into the injection chamber 2.
- the front cap 7 of the syringe preferably is made of transparent plastic and may be removably secured to the outer syringe casing l, for example, by being clamped or screwed on the cap nut 11.
- a hypodermic syringe comprising a housing
- a slidable injection cylinder disposed in said housing and provided with an injection chamber adapted to hold a relatively small
- hypodermic needle carried by said cylinder and extending outwardly through said housing
- a container adapted to hold a relatively large supply of an injectionsolution mounted for independent reciprocatory movement in said housing adjacent to said cylinder,
- valve controlled conduit means interconnecting said container and said injection chamber
- pump means in said housing having an air inlet commu nicating with the exterior of said container and an outlet communicating with said container operable by reciprocatory movement of said container to force the in jection solution from the container into said injection chamber,
- spring actuated manually controlled means operable to slide' said cylinder in said housing to insert said hypodermic needle in use and then to advance said piston in said injection chamber to eject said injection solution from said injection chamber through said hypodermic needle.
- a hypodermic syringe as defined in claim 1 including means for varying the volume of said injection chamber and therefore the amount of injection solution ejected by said piston.
- a hypodermic syringe as defined in claim 1 including adjusting means for varying the travel of said injection cylinder in said housing and consequently the insertion amount of said hypodermic needle.
- a hypodermic syringe as defined in claim 5 including spring means for holding said pump members normally apart.
- a hypodennic syringe as defined in claim 7 further including delaying means for insuring that said movement of said piston on said injection chamber will not occur until said injection cylinder has been moved a predetermined distance in said housing.
- a hypodermic syringe as defined in claim I further including a cap nut adjustably mounted on said housing, and
- a transparent cap removably connected to said cap nut engageable by said injection cylinder to control the forward travel thereof in said housing.
Landscapes
- Health & Medical Sciences (AREA)
- Vascular Medicine (AREA)
- Engineering & Computer Science (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AT149270A AT303250B (de) | 1970-02-19 | 1970-02-19 | Mit Medikamentdepot ausgestattete Injektionsspritze |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| US3677246A true US3677246A (en) | 1972-07-18 |
Family
ID=3515053
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| US116108A Expired - Lifetime US3677246A (en) | 1970-02-19 | 1971-02-17 | Hypodermic syringe |
Country Status (3)
| Country | Link |
|---|---|
| US (1) | US3677246A (de) |
| AT (1) | AT303250B (de) |
| DE (1) | DE2106338A1 (de) |
Cited By (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3848773A (en) * | 1972-03-07 | 1974-11-19 | New England Nuclear Corp | Radioactive gas dispensing device |
| US3955571A (en) * | 1974-04-03 | 1976-05-11 | The Emko Company | Rechargeable applicator for dispensing substances |
| US4140117A (en) * | 1975-05-12 | 1979-02-20 | Alza Corporation | Cartridge for liquid infusion apparatus |
| US4475905A (en) * | 1982-09-30 | 1984-10-09 | Himmelstrup Anders B | Injection device |
| DE3713508A1 (de) * | 1986-04-22 | 1987-11-05 | Phillips Pty Ltd N J | Injektionsgeraet mit wegwerfbarer patrone |
| US4781689A (en) * | 1986-11-13 | 1988-11-01 | Andrew Sealfon | Spring-operated liquid-dispensing device |
| US6090070A (en) * | 1997-02-07 | 2000-07-18 | Rhone-Poulenc Rorer Gmbh | Device for administering metered amounts of a liquid medicament |
| AU723084B2 (en) * | 1996-02-12 | 2000-08-17 | Rhone-Poulenc Rorer Arzneimittel Gmbh | A device for the output of a liquid in partitioned amounts |
| US6224572B1 (en) * | 1995-05-04 | 2001-05-01 | Sarcos L.C. | Piston-actuated attachable topical fluid delivery system |
| US20040015134A1 (en) * | 1998-11-13 | 2004-01-22 | Elan Pharma International, Ltd. | Drug delivery systems and methods |
| WO2007027203A3 (en) * | 2005-04-11 | 2007-05-18 | Becton Dickinson Co | Injection device with secondary reservoir |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE9107574U1 (de) * | 1991-06-20 | 1991-08-01 | Heraeus Kulzer GmbH & Co. KG, 63450 Hanau | Spritzenartige Vorrichtung zum Dosieren von Flüssigkeiten oder Pasten |
| DE19532410C2 (de) * | 1995-09-01 | 1998-02-05 | Gaplast Gmbh | Injektionseinrichtung |
| ATE209935T1 (de) * | 1996-09-20 | 2001-12-15 | Novo Nordisk As | Arbeitszylinder |
| DE19812366A1 (de) * | 1998-03-20 | 1999-09-23 | Berno Spaeter | Injektionsgerät zur s.c.Injektion von Medikamenten |
Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2413303A (en) * | 1944-01-17 | 1946-12-31 | Marvin L Folkman | Syringe |
| US2821195A (en) * | 1952-05-15 | 1958-01-28 | Duncan M Mclintock | Liquid-dosing instruments |
| US3104448A (en) * | 1961-09-21 | 1963-09-24 | Morrow | Mortician's body cavity injector |
| US3353537A (en) * | 1965-08-11 | 1967-11-21 | George W Knox | Automatic multi-dosage inoculating instrument |
| US3400716A (en) * | 1964-06-05 | 1968-09-10 | William H. Schultz | Multiple dosage hypodermic syringe |
| US3461867A (en) * | 1966-03-14 | 1969-08-19 | Mizzy Inc | Needleless injector |
| DE1815118A1 (de) * | 1968-12-17 | 1970-06-25 | Hoechst Ag | Zweikammer-Injektionsgeraet |
-
1970
- 1970-02-19 AT AT149270A patent/AT303250B/de not_active IP Right Cessation
-
1971
- 1971-02-10 DE DE19712106338 patent/DE2106338A1/de active Pending
- 1971-02-17 US US116108A patent/US3677246A/en not_active Expired - Lifetime
Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2413303A (en) * | 1944-01-17 | 1946-12-31 | Marvin L Folkman | Syringe |
| US2821195A (en) * | 1952-05-15 | 1958-01-28 | Duncan M Mclintock | Liquid-dosing instruments |
| US3104448A (en) * | 1961-09-21 | 1963-09-24 | Morrow | Mortician's body cavity injector |
| US3400716A (en) * | 1964-06-05 | 1968-09-10 | William H. Schultz | Multiple dosage hypodermic syringe |
| US3353537A (en) * | 1965-08-11 | 1967-11-21 | George W Knox | Automatic multi-dosage inoculating instrument |
| US3461867A (en) * | 1966-03-14 | 1969-08-19 | Mizzy Inc | Needleless injector |
| DE1815118A1 (de) * | 1968-12-17 | 1970-06-25 | Hoechst Ag | Zweikammer-Injektionsgeraet |
Cited By (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3848773A (en) * | 1972-03-07 | 1974-11-19 | New England Nuclear Corp | Radioactive gas dispensing device |
| US3955571A (en) * | 1974-04-03 | 1976-05-11 | The Emko Company | Rechargeable applicator for dispensing substances |
| US4140117A (en) * | 1975-05-12 | 1979-02-20 | Alza Corporation | Cartridge for liquid infusion apparatus |
| US4475905A (en) * | 1982-09-30 | 1984-10-09 | Himmelstrup Anders B | Injection device |
| DE3713508A1 (de) * | 1986-04-22 | 1987-11-05 | Phillips Pty Ltd N J | Injektionsgeraet mit wegwerfbarer patrone |
| US4781689A (en) * | 1986-11-13 | 1988-11-01 | Andrew Sealfon | Spring-operated liquid-dispensing device |
| US6224572B1 (en) * | 1995-05-04 | 2001-05-01 | Sarcos L.C. | Piston-actuated attachable topical fluid delivery system |
| AU723084B2 (en) * | 1996-02-12 | 2000-08-17 | Rhone-Poulenc Rorer Arzneimittel Gmbh | A device for the output of a liquid in partitioned amounts |
| US6090070A (en) * | 1997-02-07 | 2000-07-18 | Rhone-Poulenc Rorer Gmbh | Device for administering metered amounts of a liquid medicament |
| US20040015134A1 (en) * | 1998-11-13 | 2004-01-22 | Elan Pharma International, Ltd. | Drug delivery systems and methods |
| WO2007027203A3 (en) * | 2005-04-11 | 2007-05-18 | Becton Dickinson Co | Injection device with secondary reservoir |
| JP2008535636A (ja) * | 2005-04-11 | 2008-09-04 | ベクトン・ディキンソン・アンド・カンパニー | 2次リザーバ付きの注射装置 |
| US20100049140A1 (en) * | 2005-04-11 | 2010-02-25 | Marsh Ronald W | Injection device with secondary reservoir |
| US7981081B2 (en) | 2005-04-11 | 2011-07-19 | Becton, Dickinson And Company | Injection device with secondary reservoir |
Also Published As
| Publication number | Publication date |
|---|---|
| AT303250B (de) | 1972-11-10 |
| DE2106338A1 (de) | 1971-09-02 |
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