US746749A - Nasal medicator. - Google Patents
Nasal medicator. Download PDFInfo
- Publication number
- US746749A US746749A US14828403A US1903148284A US746749A US 746749 A US746749 A US 746749A US 14828403 A US14828403 A US 14828403A US 1903148284 A US1903148284 A US 1903148284A US 746749 A US746749 A US 746749A
- Authority
- US
- United States
- Prior art keywords
- nasal
- fitting
- medicator
- receptacle
- construction
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 238000010276 construction Methods 0.000 description 10
- 239000003814 drug Substances 0.000 description 7
- 238000003780 insertion Methods 0.000 description 3
- 230000037431 insertion Effects 0.000 description 3
- 210000000056 organ Anatomy 0.000 description 3
- 230000006978 adaptation Effects 0.000 description 2
- 230000015572 biosynthetic process Effects 0.000 description 2
- 239000000470 constituent Substances 0.000 description 2
- 210000004072 lung Anatomy 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 210000004400 mucous membrane Anatomy 0.000 description 2
- 230000001817 pituitary effect Effects 0.000 description 2
- 230000002889 sympathetic effect Effects 0.000 description 2
- NOOLISFMXDJSKH-UTLUCORTSA-N (+)-Neomenthol Chemical compound CC(C)[C@@H]1CC[C@@H](C)C[C@@H]1O NOOLISFMXDJSKH-UTLUCORTSA-N 0.000 description 1
- NOOLISFMXDJSKH-UHFFFAOYSA-N DL-menthol Natural products CC(C)C1CCC(C)CC1O NOOLISFMXDJSKH-UHFFFAOYSA-N 0.000 description 1
- ARPUHYJMCVWYCZ-UHFFFAOYSA-N ciprofloxacin hydrochloride hydrate Chemical compound O.Cl.C12=CC(N3CCNCC3)=C(F)C=C2C(=O)C(C(=O)O)=CN1C1CC1 ARPUHYJMCVWYCZ-UHFFFAOYSA-N 0.000 description 1
- 239000002131 composite material Substances 0.000 description 1
- 239000007799 cork Substances 0.000 description 1
- 230000002596 correlated effect Effects 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 229940059082 douche Drugs 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 229940041616 menthol Drugs 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 210000000196 olfactory nerve Anatomy 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 210000002345 respiratory system Anatomy 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/08—Inhaling devices inserted into the nose
Definitions
- My present invention does not contemplate a radical reconstruction of the constituent elements of devices of this character, but rather the adaptation of old principles with the -mechanical elements reduced to their simplest proposition and as a natural sequence accentuating the utilitarian residual benefits thereof and adapting them to subserve the highest economic ends.
- the object of my invention is the provision of a syringe, insufflator, atomizer, sprayer, injector, or inhaler consisting of a mechanical composite of tested instrumentalities or concatenations or tantamount devices for directing a medicament into or upon the nasal passages and organs and the plexus constituting the respiratory system.
- Another object'of my invention is the pro vision of a nasal medicator consisting of simple mechanical propositions correlated into a usonant ensemble for the expeditious insertion of aeriform or gaseous medicants to the pituitary or mucous membrane,the meatuses, the ramifications of the olfactory nerves, and contiguous and sympathetic organs thereof.
- Another object is the provision of a mer cable nasal medicator apposite to the ampliably subserving the highest economic ends as a natural sequence to the germanic synthesis of the mechanical construction and the intermutuality of utilization.
- Still another object is the provision of a nasal medicator for the insertion of medicaments or douches of either a'liquid, powder, or gaseous constituent into the nasal passages for the purpose of a douche, equration,
- a nasal medicator consisting of a minim nm of mechanical parts adapted to obtain a maximum ofefficiency and which can be manufactured and sold at a comparatively low price.
- my invention consists in the form, construction, and arrangement of the several elements with reference to each other and'the specific attachments with the interstinctive parts intermutually combined and in the legitimate combinations of the several parts with reference to each other and to the entire invention.
- Figure 1 is an isometrical view of my entire invention, showing one manner of application.
- Fig. 2 is a central longitudinal section of same.
- Fig. 3 is a modified form of my invention, showing a diiferent manner of application and use.
- indice A represents the mouth, and B the nose, of anindividual.
- the indice 0 represents a receptacle which I design shall contain a medicamentsuch, for instance, as a menthol or the like.
- the indice D represents the upper converging end of the receptacle 0, which is adapted for insertion in the nostrils of the patient.
- the lower end of the receptacle C is formed open, with a bushing or gasket E, formed of cork or soft rubber, adapted to fit therein, and a central opening is provided through the bushing E to receive and hold the large end of the fitting G.
- the fitting G is preferably tral opening therethrough of same general contour thereof.
- the large end of said fitting is adapted to be inserted in the opening formed U-shaped, with a cenin the bushing E and the opposite or small end to receive the lower end of the flexible tube H.
- a mouthpiece I In the upper end of the flexible tube H is inserted a mouthpiece I, with a central opening therethrough.
- F represents a medicament contained in the receptacle, and it should be of a porous or granular formation in order that it may be penetrated by a forced draft
- K and L represent the upper and lower dams, respectively, to retain the medicamentin place. Small openings are formed through the said dams in an axial direction to allow the air to pass through the space inclosed thereby.
- menthol-is placed in the receptacle 0 and secured between and by the dams K and L, and the parts of the invention are otherwise assembled substantially as shown in Fig. 2.
- the point D is then placed to or in one of the nostrils of the nose B, and the mouthpiece I is placed between the lips of the mouth A, and the air is then exhaled from the lungs through the opening in the mouthpiece I, the flexible tube H, the fitting G into the interior of the receptacle 0, where the air becomes charged with the medicament in its passage therethrough and is forced through the nostril and the meatuses to the pituitary or mucous membrane, where the medicament is desired to be effective and which by the ordinary method of inhaling the medicated air would pass beyond said parts and enter the lungs of the patient.
- the fitting G instead of being U-shaped, as shown, may, if desired, be made L-shaped, only requiring a small additional length of the tube H, but making the fitting more easy of manufacture.
- a nasal medicator In a nasal medicator, the combination, a medicament-receptacle provided with an upper converging end and a lower open end, a bushing fitted in the lower end of the receptacle, a U-shaped fitting with an opening therethrough, one end of said fitting being inserted in the opening in bushing and the other end of the fitting being inserted into the lower end of a flexible tube, the flexible tube connected to said fitting and to a mouthpiece, the mouthpiece connected to the'upper end of said flexible tube with a central opening IIO connecting therewith, a pair of perforated
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pulmonology (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Otolaryngology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
Description
. tude of its various requirements, incontest- UNITED STATES GEORGE E. SEIDEL, OF
NASAL ME iatented December 15, 1903.
RIOHMOND, INDIANA.
DICATOR.
SPECIFICATION forming part of Letters Patent No. 746,749, dated December 1903- Application filed March 18, 1903.
To aZZ whom it may concern:
Be it known that I, GEORGE E. SEIDEL, a citizen of the United States, residing in the city of Richmond, in the county of VV-ayne and State of Indiana, have invented certain new and useful Im provemeuts-in Nasal Medicators, of which the following is a specification, which when taken in connection with the accompanying drawings, forming a part thereof,is sufiiciently clear and concise as to enable others skilled in the art to which it appertains to make and use the same in its preferred and modified construction.
My present invention does not contemplate a radical reconstruction of the constituent elements of devices of this character, but rather the adaptation of old principles with the -mechanical elements reduced to their simplest proposition and as a natural sequence accentuating the utilitarian residual benefits thereof and adapting them to subserve the highest economic ends.
The object of my invention, broadly speaking, is the provision of a syringe, insufflator, atomizer, sprayer, injector, or inhaler consisting of a mechanical composite of tested instrumentalities or concatenations or tantamount devices for directing a medicament into or upon the nasal passages and organs and the plexus constituting the respiratory system.
Another object'of my invention is the pro vision of a nasal medicator consisting of simple mechanical propositions correlated into a usonant ensemble for the expeditious insertion of aeriform or gaseous medicants to the pituitary or mucous membrane,the meatuses, the ramifications of the olfactory nerves, and contiguous and sympathetic organs thereof.
Another object is the provision of a mer cable nasal medicator apposite to the ampliably subserving the highest economic ends as a natural sequence to the germanic synthesis of the mechanical construction and the intermutuality of utilization.
Still another object is the provision of a nasal medicator for the insertion of medicaments or douches of either a'liquid, powder, or gaseous constituent into the nasal passages for the purpose of a douche, equration,
Serial No. 148,284. i140 model.)
ormedicament; and, finally, another object is the provision of a new article of manufacture,
a nasal medicator consisting of a minim nm of mechanical parts adapted to obtain a maximum ofefficiency and which can be manufactured and sold at a comparatively low price.
Other objects and advantages of my invention will appear from the drawings, from the description set forth otherwheres in this specification, and from the claim hereunto appended.
With the above-named objects in View my invention consists in the form, construction, and arrangement of the several elements with reference to each other and'the specific attachments with the interstinctive parts intermutually combined and in the legitimate combinations of the several parts with reference to each other and to the entire invention.
Referring now to the drawings by the indicated figures, Figure 1 is an isometrical view of my entire invention, showing one manner of application. Fig. 2 is a central longitudinal section of same. Fig. 3 is a modified form of my invention, showing a diiferent manner of application and use.
In the drawings similar indices refer to and denote similar parts throughout the several views.
I will now describe my invention in detail, which I will state as briefly and compact-1y as I may.
In the drawings the indice A represents the mouth, and B the nose, of anindividual.
The indice 0 represents a receptacle which I design shall contain a medicamentsuch, for instance, as a menthol or the like.
The indice D represents the upper converging end of the receptacle 0, which is adapted for insertion in the nostrils of the patient. The lower end of the receptacle C is formed open, with a bushing or gasket E, formed of cork or soft rubber, adapted to fit therein, and a central opening is provided through the bushing E to receive and hold the large end of the fitting G. The fitting G is preferably tral opening therethrough of same general contour thereof. The large end of said fitting is adapted to be inserted in the opening formed U-shaped, with a cenin the bushing E and the opposite or small end to receive the lower end of the flexible tube H. In the upper end of the flexible tube H is inserted a mouthpiece I, with a central opening therethrough.
F represents a medicament contained in the receptacle, and it should be of a porous or granular formation in order that it may be penetrated by a forced draft, and K and L represent the upper and lower dams, respectively, to retain the medicamentin place. Small openings are formed through the said dams in an axial direction to allow the air to pass through the space inclosed thereby.
For use the medicament-such,forinstance,
as menthol-is placed in the receptacle 0 and secured between and by the dams K and L, and the parts of the invention are otherwise assembled substantially as shown in Fig. 2. The point D is then placed to or in one of the nostrils of the nose B, and the mouthpiece I is placed between the lips of the mouth A, and the air is then exhaled from the lungs through the opening in the mouthpiece I, the flexible tube H, the fitting G into the interior of the receptacle 0, where the air becomes charged with the medicament in its passage therethrough and is forced through the nostril and the meatuses to the pituitary or mucous membrane, where the medicament is desired to be effective and which by the ordinary method of inhaling the medicated air would pass beyond said parts and enter the lungs of the patient.
In some instances I find it advisable to modify my device to a construction on the on der of a medicinal insufiiator or atomizer, in which case I replace the U-shaped fitting G with a straight or L-shaped fitting M, thus extending the flexible tube H below and parallel with the receptacle 0, as shown in Fig. 3, and to the lower end of the tube H, I secure the fitting P, providing means whereby a rubber ball 0 may be connected thereto, and on the opposite side of the ball 0 is a valve N, connected with the interior of the ball. By this modified arrangement it will beapparent that air may be pumped into the receptacle 0 by alternately contacting and releasing the ball 0, drawing the air in through the valve N, and forcing it through the medicament and thence into the nostrils and accomplishing mechanically the same results as hereinbefore stated in regard to the method of application.
It is apparent that the fitting G instead of being U-shaped, as shown, may, if desired, be made L-shaped, only requiring a small additional length of the tube H, but making the fitting more easy of manufacture.
By the use of my improved construction, substantially as herein shown and described, I have indubitably produced a device of simple construction and when expeditiously applied with the medical ingredients will accelerate the cure of the nasal and its sympathetic organs.
The simplicity of my invention, together with its positiveness of action and elfect-iveness of the resultant operation, will appeal to any one familiar with the treatment of nasal and kindred diseases, and while I am aware that devices of a somewhat similar character have been constructed, yet in my opinion they all, more or less, lack that positiveness of action and adaptation and intermutual relationship of the several elements which should be a vital characteristic of devices of this kind, and, in my opinion, the crux of the whole matter lies'more particularly in what has been the inability heretofore of conducting the medicament to the exact spot to be treated and to allow the flow to be controlled instantly at the will of the patient. This I have accomplished in the construction herein shown and described.
My invention is perfectly adapted to accomplish the results for which it is intended, and it is evident that changes in and modifications of the specific construction herein shown and described may be made and that analogous parts may be used to accomplish the same results without departing from the spirit of my invention or sacrificing any of its many advantages, and the specific construction of the details of my invention, in which novel features are embodied, may be variously changed without altering the essential principles of the invention which are claimed as new.
Having now fully shown and described my invention and the best means for. its construction and operation to me known at this time, what I claim as new, and desire to secure by Letters Patent of the United States, 1s
In a nasal medicator, the combination, a medicament-receptacle provided with an upper converging end and a lower open end, a bushing fitted in the lower end of the receptacle, a U-shaped fitting with an opening therethrough, one end of said fitting being inserted in the opening in bushing and the other end of the fitting being inserted into the lower end of a flexible tube, the flexible tube connected to said fitting and to a mouthpiece, the mouthpiece connected to the'upper end of said flexible tube with a central opening IIO connecting therewith, a pair of perforated
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US14828403A US746749A (en) | 1903-03-18 | 1903-03-18 | Nasal medicator. |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US14828403A US746749A (en) | 1903-03-18 | 1903-03-18 | Nasal medicator. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| US746749A true US746749A (en) | 1903-12-15 |
Family
ID=2815244
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| US14828403A Expired - Lifetime US746749A (en) | 1903-03-18 | 1903-03-18 | Nasal medicator. |
Country Status (1)
| Country | Link |
|---|---|
| US (1) | US746749A (en) |
Cited By (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2818068A (en) * | 1955-09-02 | 1957-12-31 | Felice Anthony De | Air pressure eye cup |
| US5906198A (en) * | 1996-07-16 | 1999-05-25 | Flickinger; William J. | Nasal nebulizer |
| US6648848B1 (en) * | 1997-05-27 | 2003-11-18 | Direct-Haler A/S | Inhaler for powdered medicaments |
| US20040182388A1 (en) * | 1999-03-03 | 2004-09-23 | Djupesland Per Gisle | Nasal delivery method |
| US20070125371A1 (en) * | 2003-08-28 | 2007-06-07 | Optinose As | Delivery devices |
| GB2444395A (en) * | 2006-11-28 | 2008-06-04 | Optinose As | Nasal delivery devices |
| GB2468794A (en) * | 2006-11-28 | 2010-09-22 | Optinose As | Nasal delivery devices |
| US20120006323A1 (en) * | 2001-06-12 | 2012-01-12 | Optinose As | Nasal devices |
| WO2013124492A1 (en) * | 2012-02-24 | 2013-08-29 | Optinose As | Nasal delivery devices |
| USD759805S1 (en) | 2013-05-23 | 2016-06-21 | Optinose As | Nosepiece unit |
| US9452272B2 (en) | 2003-08-14 | 2016-09-27 | Optinose As | Delivery devices |
| US9522243B2 (en) | 2002-07-02 | 2016-12-20 | Optinose As | Nasal devices |
| US9566402B2 (en) | 2003-05-20 | 2017-02-14 | Optinose As | Delivery Device and Method |
| US9649456B2 (en) | 2007-04-05 | 2017-05-16 | Optinose As | Nasal administration |
| US9949923B2 (en) | 2011-03-15 | 2018-04-24 | Optinose As | Nasal delivery |
| US10076615B2 (en) | 2007-04-05 | 2018-09-18 | Optinose As | Nasal delivery |
| US10112021B2 (en) | 2006-06-08 | 2018-10-30 | Optinose As | Intranasal administration |
| US10124132B2 (en) | 2006-03-06 | 2018-11-13 | Optinose As | Nasal delivery |
| US10179216B2 (en) | 2012-02-24 | 2019-01-15 | Optinose As | Nasal delivery devices |
| US10252010B2 (en) | 2007-10-03 | 2019-04-09 | Optinose As | Nasal delivery devices |
| US10300229B2 (en) | 2012-02-24 | 2019-05-28 | Optinose As | Nasal delivery devices |
| US10398859B2 (en) | 2004-09-15 | 2019-09-03 | Optinose As | Nasal delivery devices |
| US10478574B2 (en) | 2006-01-19 | 2019-11-19 | Optinose As | Nasal administration |
| US10525218B2 (en) | 2006-11-28 | 2020-01-07 | Optinose As | Nasal delivery devices |
| US10639438B2 (en) | 2006-11-28 | 2020-05-05 | Optinose As | Delivery devices |
| US10682331B2 (en) | 2012-02-24 | 2020-06-16 | Nasoneb, Inc. | Nasal drug delivery and method of making same |
| US10765829B2 (en) | 2006-07-25 | 2020-09-08 | Optinose As | Delivery of gases to the nasal airway |
| US10864334B2 (en) | 2006-03-23 | 2020-12-15 | Optinose As | Nasal delivery |
| US10940277B2 (en) | 2014-11-19 | 2021-03-09 | Optinose As | Intranasal administration |
| US11291626B2 (en) | 2010-09-14 | 2022-04-05 | Optinose As | Nasal delivery of oxytocin |
| US11554229B2 (en) | 2013-03-26 | 2023-01-17 | OptiNose Inc. | Nasal administration |
| US11571531B2 (en) | 2005-02-23 | 2023-02-07 | OptiNose Inc. | Powder delivery devices |
| US20230062996A1 (en) * | 2019-10-11 | 2023-03-02 | Rocket Science Health Corp. | Intranasal drug delivery device, system, and process |
| US12083270B2 (en) | 2006-02-14 | 2024-09-10 | OptiNose Inc. | Delivery device and method |
| US12516267B2 (en) | 2019-12-09 | 2026-01-06 | Aak Ab (Publ) | Wax compositions for use in candles and methods of preparing wax compositions |
| US12616806B2 (en) | 2022-12-12 | 2026-05-05 | Optinose, Inc. | Nasal administration |
-
1903
- 1903-03-18 US US14828403A patent/US746749A/en not_active Expired - Lifetime
Cited By (75)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2818068A (en) * | 1955-09-02 | 1957-12-31 | Felice Anthony De | Air pressure eye cup |
| US5906198A (en) * | 1996-07-16 | 1999-05-25 | Flickinger; William J. | Nasal nebulizer |
| US6811543B2 (en) * | 1997-05-27 | 2004-11-02 | Direct-Haler A/S | Method for introducing a powdered substance into a nostril |
| US6648848B1 (en) * | 1997-05-27 | 2003-11-18 | Direct-Haler A/S | Inhaler for powdered medicaments |
| US20060219240A1 (en) * | 1999-03-03 | 2006-10-05 | Djupesland Per G | Nasal delivery device |
| US8555878B2 (en) | 1999-03-03 | 2013-10-15 | Optinose As | Nasal delivery device |
| EP1555038A3 (en) * | 1999-03-03 | 2006-05-10 | Optinose AS | Nasal delivery device |
| US20060219241A1 (en) * | 1999-03-03 | 2006-10-05 | Djupesland Per G | Nasal delivery device |
| US8555877B2 (en) | 1999-03-03 | 2013-10-15 | Optinose As | Nasal delivery device |
| US20060225732A1 (en) * | 1999-03-03 | 2006-10-12 | Djupesland Per G | Nasal delivery device |
| US20060231094A1 (en) * | 1999-03-03 | 2006-10-19 | Djupesland Per G | Nasal delivery device |
| EP1555038A2 (en) | 1999-03-03 | 2005-07-20 | Optinose AS | Nasal delivery device |
| US9119932B2 (en) | 1999-03-03 | 2015-09-01 | Optinose As | Nasal delivery device |
| US9072857B2 (en) | 1999-03-03 | 2015-07-07 | Optinose As | Nasal delivery device |
| US8327844B2 (en) * | 1999-03-03 | 2012-12-11 | Optinose As | Nasal delivery method |
| US20040182388A1 (en) * | 1999-03-03 | 2004-09-23 | Djupesland Per Gisle | Nasal delivery method |
| US9205208B2 (en) * | 2001-06-12 | 2015-12-08 | Optinose As | Nasal devices |
| US20120006323A1 (en) * | 2001-06-12 | 2012-01-12 | Optinose As | Nasal devices |
| US9522243B2 (en) | 2002-07-02 | 2016-12-20 | Optinose As | Nasal devices |
| US10286164B2 (en) | 2003-05-20 | 2019-05-14 | Optinose As | Delivery device and method |
| US9566402B2 (en) | 2003-05-20 | 2017-02-14 | Optinose As | Delivery Device and Method |
| US9452272B2 (en) | 2003-08-14 | 2016-09-27 | Optinose As | Delivery devices |
| US10737045B2 (en) | 2003-08-28 | 2020-08-11 | Optinose As | Delivery devices |
| US8800555B2 (en) * | 2003-08-28 | 2014-08-12 | Optinose As | Delivery devices |
| US20070125371A1 (en) * | 2003-08-28 | 2007-06-07 | Optinose As | Delivery devices |
| US10398859B2 (en) | 2004-09-15 | 2019-09-03 | Optinose As | Nasal delivery devices |
| US11571531B2 (en) | 2005-02-23 | 2023-02-07 | OptiNose Inc. | Powder delivery devices |
| US10478574B2 (en) | 2006-01-19 | 2019-11-19 | Optinose As | Nasal administration |
| US12083270B2 (en) | 2006-02-14 | 2024-09-10 | OptiNose Inc. | Delivery device and method |
| US10124132B2 (en) | 2006-03-06 | 2018-11-13 | Optinose As | Nasal delivery |
| US10864334B2 (en) | 2006-03-23 | 2020-12-15 | Optinose As | Nasal delivery |
| US10112021B2 (en) | 2006-06-08 | 2018-10-30 | Optinose As | Intranasal administration |
| US10765829B2 (en) | 2006-07-25 | 2020-09-08 | Optinose As | Delivery of gases to the nasal airway |
| US11690969B2 (en) | 2006-07-25 | 2023-07-04 | OptiNose Inc. | Delivery of gases to the nasal airway |
| GB2444395B (en) * | 2006-11-28 | 2009-12-09 | Optinose As | Delivery devices |
| GB2444395A (en) * | 2006-11-28 | 2008-06-04 | Optinose As | Nasal delivery devices |
| US10639438B2 (en) | 2006-11-28 | 2020-05-05 | Optinose As | Delivery devices |
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| US20110126830A1 (en) * | 2006-11-28 | 2011-06-02 | Optinose As | Delivery devices |
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| US9038630B2 (en) | 2006-11-28 | 2015-05-26 | Optinose As | Delivery devices |
| GB2468794B (en) * | 2006-11-28 | 2011-07-13 | Optinose As | Delivery devices |
| GB2468794A (en) * | 2006-11-28 | 2010-09-22 | Optinose As | Nasal delivery devices |
| US9649456B2 (en) | 2007-04-05 | 2017-05-16 | Optinose As | Nasal administration |
| US10076615B2 (en) | 2007-04-05 | 2018-09-18 | Optinose As | Nasal delivery |
| US10722667B2 (en) | 2007-04-05 | 2020-07-28 | Optinose As | Nasal administration |
| US11602603B2 (en) | 2007-10-03 | 2023-03-14 | Optinose, Inc. | Nasal delivery devices |
| US10252010B2 (en) | 2007-10-03 | 2019-04-09 | Optinose As | Nasal delivery devices |
| US11083858B2 (en) | 2007-10-03 | 2021-08-10 | Optinose As | Nasal delivery devices |
| US11291626B2 (en) | 2010-09-14 | 2022-04-05 | Optinose As | Nasal delivery of oxytocin |
| US9949923B2 (en) | 2011-03-15 | 2018-04-24 | Optinose As | Nasal delivery |
| US10179216B2 (en) | 2012-02-24 | 2019-01-15 | Optinose As | Nasal delivery devices |
| US10076614B2 (en) * | 2012-02-24 | 2018-09-18 | Optinose As | Nasal delivery devices |
| WO2013124492A1 (en) * | 2012-02-24 | 2013-08-29 | Optinose As | Nasal delivery devices |
| US20150013677A1 (en) * | 2012-02-24 | 2015-01-15 | Optinose As | Nasal Delivery Devices |
| US10300229B2 (en) | 2012-02-24 | 2019-05-28 | Optinose As | Nasal delivery devices |
| JP2015507990A (en) * | 2012-02-24 | 2015-03-16 | オプティノーズ アズ | Nasal delivery device |
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