US7670845B2 - Indicator granular material - Google Patents

Indicator granular material Download PDF

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Publication number
US7670845B2
US7670845B2 US11/575,448 US57544805A US7670845B2 US 7670845 B2 US7670845 B2 US 7670845B2 US 57544805 A US57544805 A US 57544805A US 7670845 B2 US7670845 B2 US 7670845B2
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US
United States
Prior art keywords
granular material
cat
granular
indicator
polymer layer
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Expired - Fee Related, expires
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US11/575,448
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US20090181466A1 (en
Inventor
Gunnar Wenzel
Dietmar Lange
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Mars Inc
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Mars Inc
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Assigned to MARS INCORPORATED reassignment MARS INCORPORATED ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: LANGE, DIETMAR, WENZEL, GUNNAR
Publication of US20090181466A1 publication Critical patent/US20090181466A1/en
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    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K1/00Housing animals; Equipment therefor
    • A01K1/015Floor coverings, e.g. bedding-down sheets ; Stable floors
    • A01K1/0152Litter
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/10Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing

Definitions

  • a wide variety of indicators for measuring the pH of a cat's urine are known from the state of the art. As a rule, such indicators take the form of granules or small scraps of various kinds, such as small strips of paper, which are impregnated with a wide variety of pH indicators. These indicators react to a change in pH by changing colour.
  • EP 0 569 232 A1 discloses a pH indicator material in which a coating made from an aqueous solution of a water-soluble polymer is applied to an inert core substrate, which coating likewise contains a sufficient quantity of a water-soluble pH indicator dye.
  • the pH indicator dye can alter its colour and thus indicate the change in the pH of a cat's urine.
  • the object the present invention is to provide an indicator material which overcomes the disadvantages of the state of the art, i.e. in particular which makes it possible to determine unambiguously whether the pH of the urine has changed beyond a threshold level.
  • an indicator material should be capable of being used in a simple manner in a conventional cat lavatory.
  • a second granular material is substantially completely coated with a second polymer layer, which is solid at a first pH and is dissolved at a third pH.
  • indicator granular material is preferred in which the second pH lies in a range above 7, preferably above 7.5.
  • indicator granular material is preferably provided in which the first and second granular materials comprise biodegradable plastics material.
  • the second polymer coating is a copolymer of methyl methacrylate, butyl methacrylate and dimethyl amino-ethyl methacrylate, preferably in a ratio of 25:25:50.
  • indicator granular material in which the first and second polymer coatings are opaque.
  • the invention also encompasses a cat lavatory comprising indicator granular material in accordance with the invention.
  • an indicator granular material in accordance with the invention in a cat lavatory in order to determine the pH of a cat's urine.
  • the present invention offers a completely novel approach to determining the pH of a cat's urine in a cat lavatory.
  • the indicator granular material of the invention yields an unambiguous yes/no criterion as to whether certain pH threshold values have been reached. A difficult interpretation of the colour change in conventional indicators is no longer necessary.
  • the polymer coatings can be applied to the granular materials in a simple manner as solutions or suspensions, whereupon the solvent or suspending agent is evaporated.
  • FIG. 1 schematically shows the dissolution of a polymer layer of an indicator granular material in accordance with the invention as a function of the pH.
  • Section ( 1 ) of the figure shows plastics granular material 2 coated with an intact polymer coating 1 in order to form indicator granular material 3 .
  • Section ( 2 ) of the figure shows a condition of the indicator granular material 3 when the pH is in a critical range: the polymer coating around the plastics granular material 2 is becoming detached.
  • section ( 3 ) shows the indicator granular material 3 from which the polymer coating 1 has become completely detached. If the plastics granular material 2 is dyed, the colour indicates unambiguously that the pH of the cat urine is not within the desired range.
  • the indicator granular material of the invention makes it possible unambiguously and objectively to indicate a pH change beyond a threshold value.
  • the indicator granular material of the invention can be used not only for cats, but also for dogs and other small animals.

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  • Life Sciences & Earth Sciences (AREA)
  • Environmental Sciences (AREA)
  • Zoology (AREA)
  • Animal Husbandry (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)
US11/575,448 2004-09-23 2005-09-02 Indicator granular material Expired - Fee Related US7670845B2 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE102004046102 2004-09-23
DE102004046102A DE102004046102B4 (de) 2004-09-23 2004-09-23 Indikatorgranulat
DE102004046102.3 2004-09-23
PCT/EP2005/009453 WO2006032353A1 (en) 2004-09-23 2005-09-02 Indicator granular material

Publications (2)

Publication Number Publication Date
US20090181466A1 US20090181466A1 (en) 2009-07-16
US7670845B2 true US7670845B2 (en) 2010-03-02

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Family Applications (1)

Application Number Title Priority Date Filing Date
US11/575,448 Expired - Fee Related US7670845B2 (en) 2004-09-23 2005-09-02 Indicator granular material

Country Status (6)

Country Link
US (1) US7670845B2 (de)
EP (1) EP1791420B1 (de)
AT (1) ATE534287T1 (de)
AU (1) AU2005287648B2 (de)
DE (1) DE102004046102B4 (de)
WO (1) WO2006032353A1 (de)

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090325304A1 (en) * 2008-02-28 2009-12-31 Francois Mestrallet Mammalian Disease Detection System
US20130017612A1 (en) * 2011-07-11 2013-01-17 United States Of America As Represented By The Administrator Of The National Aeronautics And Spac pH-Sensitive Microparticles with Matrix-Dispersed Active Agent
US9908799B2 (en) 2014-05-23 2018-03-06 Nch Corporation Method for improving quality of aquaculture pond water
US10653729B2 (en) 2013-10-25 2020-05-19 Nch Corporation Delivery system and probiotic composition for animals and plants
US10660301B1 (en) * 2015-08-07 2020-05-26 Pretty Litter, Inc. Health monitoring cat litter
US10766799B2 (en) 2014-05-23 2020-09-08 Nch Corporation Method for improving quality of aquaculture pond water using a nutrient germinant composition and spore incubation method
US11401500B2 (en) 2018-08-29 2022-08-02 Nch Corporation System, method, and composition for incubating spores for use in aquaculture, agriculture, wastewater, and environmental remediation applications

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US8755747B2 (en) 2006-10-31 2014-06-17 Qualcomm Incorporated Techniques to control transmit power for a shared antenna architecture
US8909165B2 (en) * 2009-03-09 2014-12-09 Qualcomm Incorporated Isolation techniques for multiple co-located radio modules
US9693390B2 (en) 2009-06-01 2017-06-27 Qualcomm Incorporated Techniques to manage a mobile device based on network density
DE102011075667A1 (de) * 2011-05-11 2012-11-15 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Verpackung
DE102011082716A1 (de) * 2011-09-14 2013-03-14 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Indikatorelement mit einer von einer in kontakt zu bringenden substanz abhängigen farbgebung
US9291570B2 (en) * 2013-06-26 2016-03-22 Eastman Kodak Company Reactive indicator compositions and articles containing same
US9289528B2 (en) * 2013-06-26 2016-03-22 Eastman Kodak Company Methods for using indicator compositions
DE102017118504A1 (de) * 2017-08-14 2019-02-14 Endress+Hauser Conducta Gmbh+Co. Kg Schutzvorrichtung für einen optochemischen Sensor und entsprechender optochemischer Sensor

Citations (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3051661A (en) * 1956-07-03 1962-08-28 Miles Lab ph indicator units in tablet form
EP0088951A2 (de) 1982-03-11 1983-09-21 Röhm Gmbh Verfahren zum Überziehen von Arzneiformen mittels eines in Wasser dispergierten Überzugsmittels
US5143023A (en) 1990-10-16 1992-09-01 Kleanheart, Inc. Animal litter with chemically bound chemical indicators
EP0569232A1 (de) 1992-05-05 1993-11-10 Anitox Corporation PH-Indikatormaterial und dieses Material enthaltendes Katzenstreu
US5371054A (en) 1993-08-13 1994-12-06 Engelhard Corporation Compositions for use as diagnostic animal litter and methods for their preparation
US5468450A (en) * 1993-12-16 1995-11-21 Michael; Richard D. Expanding vehicle for colorimetric diagnostic assays
US5534269A (en) 1993-07-05 1996-07-09 Takeda Chemical Industries, Ltd. Method of producing sustained-release preparation
US5554147A (en) * 1994-02-01 1996-09-10 Caphco, Inc. Compositions and devices for controlled release of active ingredients
US5996534A (en) * 1996-07-11 1999-12-07 Pet Eceology Brands, Inc. Animal litter having the property of detecting urinary infection in felines
US6019062A (en) 1997-12-15 2000-02-01 Lombard; Marsha M. Animal litter
EP1029448A1 (de) 1997-10-24 2000-08-23 Tolsa S.A. Antibackerielles mittel, ihre herstellung und verwendung
US6162646A (en) 1996-04-03 2000-12-19 William H. Webster Urine pH indicator system and associated methods
US6309666B1 (en) 1995-07-20 2001-10-30 Tanabe Seiyaku Co., Ltd. Pharmaceutical preparation in form of coated capsule releasable at lower part of digestive tract
US6376252B1 (en) 1999-08-19 2002-04-23 Environmental Test Systems, Inc. Preparation and method for cat box filler additive capable of detecting feline lower urinary tract disease (FLUTD)
US20020133189A1 (en) * 2001-02-09 2002-09-19 Concentric Medical, Inc., A Delaware Corporation Methods and devices for delivering occlusion elements
DE10260920A1 (de) 2002-12-20 2004-07-01 Röhm GmbH & Co. KG Verfahren zur Herstellung von Arnzeiformen oder Nahrungsergänzungsmitteln mit pigmentierten Polymerüberzügen
US20050123596A1 (en) * 2003-09-23 2005-06-09 Kohane Daniel S. pH-triggered microparticles

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10044299A1 (de) * 2000-09-07 2002-03-21 Roehm Gmbh Multipartikuläre Arzneiform und Verfahren zu ihrer Herstellung

Patent Citations (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3051661A (en) * 1956-07-03 1962-08-28 Miles Lab ph indicator units in tablet form
EP0088951A2 (de) 1982-03-11 1983-09-21 Röhm Gmbh Verfahren zum Überziehen von Arzneiformen mittels eines in Wasser dispergierten Überzugsmittels
US4520172A (en) 1982-03-11 1985-05-28 Rohm Gmbh Method for coating medicaments
US5143023A (en) 1990-10-16 1992-09-01 Kleanheart, Inc. Animal litter with chemically bound chemical indicators
EP0569232A1 (de) 1992-05-05 1993-11-10 Anitox Corporation PH-Indikatormaterial und dieses Material enthaltendes Katzenstreu
US5267532A (en) * 1992-05-05 1993-12-07 Anitox Corporation pH-indicating material and cat litter containing same
DE69420632T2 (de) 1993-07-05 2000-03-02 Takeda Chemical Industries, Ltd. Verfahren zur Herstellung von Arzneizubereitungen mit verzögerter Wirkstoffabgabe
US5534269A (en) 1993-07-05 1996-07-09 Takeda Chemical Industries, Ltd. Method of producing sustained-release preparation
US5371054A (en) 1993-08-13 1994-12-06 Engelhard Corporation Compositions for use as diagnostic animal litter and methods for their preparation
US5468450A (en) * 1993-12-16 1995-11-21 Michael; Richard D. Expanding vehicle for colorimetric diagnostic assays
US5554147A (en) * 1994-02-01 1996-09-10 Caphco, Inc. Compositions and devices for controlled release of active ingredients
US6309666B1 (en) 1995-07-20 2001-10-30 Tanabe Seiyaku Co., Ltd. Pharmaceutical preparation in form of coated capsule releasable at lower part of digestive tract
DE69624047T2 (de) 1995-07-20 2003-08-14 Tanabe Seiyaku Co., Ltd. Im unteren Teil des Verdauungstrakts freisetzende pharmazeutische Zubereitung in Form einer beschichteten Kapsel
US6162646A (en) 1996-04-03 2000-12-19 William H. Webster Urine pH indicator system and associated methods
US5996534A (en) * 1996-07-11 1999-12-07 Pet Eceology Brands, Inc. Animal litter having the property of detecting urinary infection in felines
EP1029448A1 (de) 1997-10-24 2000-08-23 Tolsa S.A. Antibackerielles mittel, ihre herstellung und verwendung
US6019062A (en) 1997-12-15 2000-02-01 Lombard; Marsha M. Animal litter
US6376252B1 (en) 1999-08-19 2002-04-23 Environmental Test Systems, Inc. Preparation and method for cat box filler additive capable of detecting feline lower urinary tract disease (FLUTD)
US20020133189A1 (en) * 2001-02-09 2002-09-19 Concentric Medical, Inc., A Delaware Corporation Methods and devices for delivering occlusion elements
DE10260920A1 (de) 2002-12-20 2004-07-01 Röhm GmbH & Co. KG Verfahren zur Herstellung von Arnzeiformen oder Nahrungsergänzungsmitteln mit pigmentierten Polymerüberzügen
US7494690B2 (en) 2002-12-20 2009-02-24 Roehm Gmbh & Co. Kg Method of producing pharmaceuticals or food supplements comprising pigmented polymer coatings
US20050123596A1 (en) * 2003-09-23 2005-06-09 Kohane Daniel S. pH-triggered microparticles

Cited By (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090325304A1 (en) * 2008-02-28 2009-12-31 Francois Mestrallet Mammalian Disease Detection System
US8062902B2 (en) * 2008-02-28 2011-11-22 Nullodor Usa Llc Mammalian disease detection system
US20130017612A1 (en) * 2011-07-11 2013-01-17 United States Of America As Represented By The Administrator Of The National Aeronautics And Spac pH-Sensitive Microparticles with Matrix-Dispersed Active Agent
US8859288B2 (en) * 2011-07-11 2014-10-14 The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration pH-sensitive microparticles with matrix-dispersed active agent
US10653729B2 (en) 2013-10-25 2020-05-19 Nch Corporation Delivery system and probiotic composition for animals and plants
US12115199B2 (en) 2013-10-25 2024-10-15 Nch Corporation Delivery system and probiotic composition for animals and plants
US9908799B2 (en) 2014-05-23 2018-03-06 Nch Corporation Method for improving quality of aquaculture pond water
US10766799B2 (en) 2014-05-23 2020-09-08 Nch Corporation Method for improving quality of aquaculture pond water using a nutrient germinant composition and spore incubation method
US10660301B1 (en) * 2015-08-07 2020-05-26 Pretty Litter, Inc. Health monitoring cat litter
US11076577B1 (en) * 2015-08-07 2021-08-03 Pretty Litter, Inc. Health monitoring cat litter
US12250922B2 (en) 2015-08-07 2025-03-18 Pretty Litter, Inc. Health monitoring cat litter
US11401500B2 (en) 2018-08-29 2022-08-02 Nch Corporation System, method, and composition for incubating spores for use in aquaculture, agriculture, wastewater, and environmental remediation applications

Also Published As

Publication number Publication date
EP1791420A1 (de) 2007-06-06
DE102004046102A1 (de) 2006-04-06
ATE534287T1 (de) 2011-12-15
DE102004046102B4 (de) 2009-09-03
EP1791420B1 (de) 2011-11-23
WO2006032353A1 (en) 2006-03-30
US20090181466A1 (en) 2009-07-16
AU2005287648A1 (en) 2006-03-30
AU2005287648B2 (en) 2009-08-20

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Owner name: MARS INCORPORATED, VIRGINIA

Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNORS:WENZEL, GUNNAR;LANGE, DIETMAR;REEL/FRAME:020002/0782;SIGNING DATES FROM 20070323 TO 20070402

Owner name: MARS INCORPORATED,VIRGINIA

Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNORS:WENZEL, GUNNAR;LANGE, DIETMAR;SIGNING DATES FROM 20070323 TO 20070402;REEL/FRAME:020002/0782

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Effective date: 20180302