USB450708I5 - Tetrahydropyran-2-Ols - Google Patents

Tetrahydropyran-2-Ols

Info

Publication number
USB450708I5
USB450708I5 US45070874A USB450708I5 US B450708 I5 USB450708 I5 US B450708I5 US 45070874 A US45070874 A US 45070874A US B450708 I5 USB450708 I5 US B450708I5
Authority
US
United States
Prior art keywords
ols
tetrahydropyran
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
Inventor
Gabriel Saucy
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US00057372A external-priority patent/US3816458A/en
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of USB450708I5 publication Critical patent/USB450708I5/en
Application granted granted Critical
Publication of US3989724A publication Critical patent/US3989724A/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/10—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/16—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D309/28—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/30—Oxygen atoms, e.g. delta-lactones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/78—Ring systems having three or more relevant rings
    • C07D311/92—Naphthopyrans; Hydrogenated naphthopyrans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/94—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems condensed with rings other than six-membered or with ring systems containing such rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D315/00—Heterocyclic compounds containing rings having one oxygen atom as the only ring hetero atom according to more than one of groups C07D303/00 - C07D313/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D317/16—Radicals substituted by halogen atoms or nitro radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D317/26—Radicals substituted by doubly bound oxygen or sulfur atoms or by two such atoms singly bound to the same carbon atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/74—Naphthothiophenes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J73/00—Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00—Systems containing at least three condensed rings
    • C07C2603/02—Ortho- or ortho- and peri-condensed systems
    • C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
    • C07C2603/06—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members
    • C07C2603/10—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings
    • C07C2603/12—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings only one five-membered ring
    • C07C2603/16—Benz[e]indenes; Hydrogenated benz[e]indenes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
US05/450,708 1967-11-02 1974-03-13 Tetrahydropyran-2-ols Expired - Lifetime US3989724A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US67998967A 1967-11-02 1967-11-02
US00057372A US3816458A (en) 1966-05-13 1970-07-22 3-substituted 6alpha,beta-alkyl-cyclopenta(f)(1)benzopyrans and-naphto(2,1-b)pyrans

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
US00057372A Division US3816458A (en) 1966-05-13 1970-07-22 3-substituted 6alpha,beta-alkyl-cyclopenta(f)(1)benzopyrans and-naphto(2,1-b)pyrans

Publications (2)

Publication Number Publication Date
USB450708I5 true USB450708I5 (en) 1976-03-09
US3989724A US3989724A (en) 1976-11-02

Family

ID=42025733

Family Applications (3)

Application Number Title Priority Date Filing Date
US450694A Expired - Lifetime US3880911A (en) 1967-11-02 1974-03-13 Des-A steroidal intermediates
US05/450,708 Expired - Lifetime US3989724A (en) 1967-11-02 1974-03-13 Tetrahydropyran-2-ols
US450692A Expired - Lifetime US3892779A (en) 1967-11-02 1974-03-13 Steroidal intermediates

Family Applications Before (1)

Application Number Title Priority Date Filing Date
US450694A Expired - Lifetime US3880911A (en) 1967-11-02 1974-03-13 Des-A steroidal intermediates

Family Applications After (1)

Application Number Title Priority Date Filing Date
US450692A Expired - Lifetime US3892779A (en) 1967-11-02 1974-03-13 Steroidal intermediates

Country Status (1)

Country Link
US (3) US3880911A (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3980687A (en) * 1966-05-26 1976-09-14 Roussel-Uclaf Intermediates for the preparation of 17-substituted-Δ4 -gonenes
JPH0449269A (en) * 1990-06-14 1992-02-18 Asahi Denka Kogyo Kk Optically active pentane derivative
US5243096A (en) * 1990-06-14 1993-09-07 Asahi Denka Kogyo K.K. Optically active pentane derivatives and intermediates thereof, and process for manufacturing same
JP2004522754A (en) * 2001-02-02 2004-07-29 ファルマシア・コーポレーション Use of a cyclooxygenase-2 inhibitor and a sex steroid as a combination therapy for the treatment and prevention of dysmenorrhea

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3631039A (en) * 1969-04-21 1971-12-28 Hoffmann La Roche 2-amino ethyl-2-hydroxy - 6-vinyl tetrahydropyrans tautomers and optical enantiomers thereof
US3655695A (en) * 1969-05-21 1972-04-11 David Andrews 6-alkyl-substituted tetrahydropyran-2-ols and process for their production
US3813417A (en) * 1970-08-26 1974-05-28 Hoffmann La Roche Cycloalkyl(f)(l)benzopyrans

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3294819A (en) * 1964-12-17 1966-12-27 Squibb & Sons Inc Synthesis of steroids
US3644425A (en) * 1967-08-04 1972-02-22 American Home Prod 10-methyl-13-ethylgon-4 9(11)-dienes
FR1574693A (en) * 1968-01-26 1969-07-18
US3793374A (en) * 1971-03-08 1974-02-19 Hoffmann La Roche Intermediates useful in steroid total synthesis and processes therefor
US3694463A (en) * 1971-04-23 1972-09-26 David Andrews 3-vinyl-cyclo penta (fm{11 )benzopyrans

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3631039A (en) * 1969-04-21 1971-12-28 Hoffmann La Roche 2-amino ethyl-2-hydroxy - 6-vinyl tetrahydropyrans tautomers and optical enantiomers thereof
US3655695A (en) * 1969-05-21 1972-04-11 David Andrews 6-alkyl-substituted tetrahydropyran-2-ols and process for their production
US3813417A (en) * 1970-08-26 1974-05-28 Hoffmann La Roche Cycloalkyl(f)(l)benzopyrans

Also Published As

Publication number Publication date
US3989724A (en) 1976-11-02
US3880911A (en) 1975-04-29
US3892779A (en) 1975-07-01

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