WO1989005351A3 - RECEPTEUR DE Fc-GAMMA HUMAIN - Google Patents

RECEPTEUR DE Fc-GAMMA HUMAIN Download PDF

Info

Publication number
WO1989005351A3
WO1989005351A3 PCT/US1988/004240 US8804240W WO8905351A3 WO 1989005351 A3 WO1989005351 A3 WO 1989005351A3 US 8804240 W US8804240 W US 8804240W WO 8905351 A3 WO8905351 A3 WO 8905351A3
Authority
WO
WIPO (PCT)
Prior art keywords
receptor
human
useful
immunoglobulin
gamma receptor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US1988/004240
Other languages
English (en)
Other versions
WO1989005351A2 (fr
Inventor
Kevin W Moore
Gary A Peltz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Schering Biotech Corp
Original Assignee
Schering Biotech Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Biotech Corp filed Critical Schering Biotech Corp
Publication of WO1989005351A2 publication Critical patent/WO1989005351A2/fr
Publication of WO1989005351A3 publication Critical patent/WO1989005351A3/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/564—Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/70535—Fc-receptors, e.g. CD16, CD32, CD64 (CD2314/705F)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Zoology (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Rheumatology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Toxicology (AREA)
  • Food Science & Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Rehabilitation Therapy (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Un clone d'ADNc code un récepteur humain pour la partie Fc de l'immunoglobuline G. Des formes solubles du récepteur peuvent être utiles dans le traitement de troubles associés à une production excessive d'immunoglobuline G. Des cellules exprimant les formes du récepteur liées à la membrane sont utiles dans des analyses de détection de complexes immuns, dont les niveaux élevés sont associés à de nombreux états de maladies, entre autres le lupus érythémateux de l'organisme (SLE) ainsi que les rhumatismes articulaires.
PCT/US1988/004240 1987-12-04 1988-12-01 RECEPTEUR DE Fc-GAMMA HUMAIN Ceased WO1989005351A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US12900287A 1987-12-04 1987-12-04
US129,002 1987-12-04

Publications (2)

Publication Number Publication Date
WO1989005351A2 WO1989005351A2 (fr) 1989-06-15
WO1989005351A3 true WO1989005351A3 (fr) 1989-08-10

Family

ID=22438026

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1988/004240 Ceased WO1989005351A2 (fr) 1987-12-04 1988-12-01 RECEPTEUR DE Fc-GAMMA HUMAIN

Country Status (3)

Country Link
EP (1) EP0319307A3 (fr)
AU (1) AU3284289A (fr)
WO (1) WO1989005351A2 (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5985599A (en) * 1986-05-29 1999-11-16 The Austin Research Institute FC receptor for immunoglobulin
WO1991006570A1 (fr) * 1989-10-25 1991-05-16 The University Of Melbourne MOLECULES RECEPTRICES Fc HYBRIDES
EP0495376B1 (fr) * 1991-01-15 1997-05-28 Bayer Corporation Complémentation des récepteurs de surface cellulaire
JP3619282B2 (ja) * 1994-04-01 2005-02-09 中外製薬株式会社 ＩｇＧＦｃ部結合タンパク質をコードする遺伝子
US5830652A (en) * 1994-08-30 1998-11-03 New York Society For The Ruptured And Crippled Maintaining The Hospital For Special Surgery Method for determining predisposition to severe forms of autoimmune disease by determining Fcy receptor allelic patterns
EP1006183A1 (fr) 1998-12-03 2000-06-07 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Récepteurs Fc recombinantes et solubles
US7622260B2 (en) 2001-09-05 2009-11-24 The Brigham And Women's Hospital, Inc. Diagnostic and prognostic tests
CA2512974A1 (fr) 2003-01-13 2004-07-29 Macrogenics, Inc. Proteines de fusion fc.gamma.r solubles et leurs procedes d'utilisation

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1987007277A1 (fr) * 1986-05-29 1987-12-03 The University Of Melbourne Recepteur fc de l'immunoglobuline

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1987007277A1 (fr) * 1986-05-29 1987-12-03 The University Of Melbourne Recepteur fc de l'immunoglobuline

Also Published As

Publication number Publication date
EP0319307A2 (fr) 1989-06-07
AU3284289A (en) 1989-07-05
EP0319307A3 (fr) 1989-08-30
WO1989005351A2 (fr) 1989-06-15

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