WO1995008352A1 - Solutions d'entretien de lentilles de contact - Google Patents

Solutions d'entretien de lentilles de contact Download PDF

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Publication number
WO1995008352A1
WO1995008352A1 PCT/FI1994/000392 FI9400392W WO9508352A1 WO 1995008352 A1 WO1995008352 A1 WO 1995008352A1 FI 9400392 W FI9400392 W FI 9400392W WO 9508352 A1 WO9508352 A1 WO 9508352A1
Authority
WO
WIPO (PCT)
Prior art keywords
weight
ethyl
care solution
detergent
care
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/FI1994/000392
Other languages
English (en)
Inventor
Olavi Nieminen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Finnsusp Oy AB
Original Assignee
Finnsusp Oy AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Finnsusp Oy AB filed Critical Finnsusp Oy AB
Priority to AU75389/94A priority Critical patent/AU7538994A/en
Priority to EP94925504A priority patent/EP0728020A1/fr
Priority to JP7509579A priority patent/JPH09503134A/ja
Publication of WO1995008352A1 publication Critical patent/WO1995008352A1/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L12/00—Methods or apparatus for disinfecting or sterilising contact lenses; Accessories therefor
    • A61L12/08—Methods or apparatus for disinfecting or sterilising contact lenses; Accessories therefor using chemical substances
    • A61L12/14—Organic compounds not covered by groups A61L12/10 or A61L12/12
    • A61L12/141—Biguanides, e.g. chlorhexidine
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D1/00—Detergent compositions based essentially on surface-active compounds; Use of these compounds as a detergent
    • C11D1/66—Non-ionic compounds
    • C11D1/662—Carbohydrates or derivatives
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/0005—Other compounding ingredients characterised by their effect
    • C11D3/0078—Compositions for cleaning contact lenses, spectacles or lenses

Definitions

  • the invention relates to the use of a biode ⁇ gradable detergent in contact lens care solutions, a care solution containing such detergent, and a method for the care of contact lenses.
  • the use of a separate detergent and disinfectant complicates the care of contact lenses. It would therefore be highly desirable to provide a combined agent which is both an effective detergent and an effective disinfectant.
  • Previous detergents have been toxic to the eyes, and so it has been necessary to use a separate rinsing solution after cleaning. It has now been unexpectedly found that when a biodegradable detergent is used in contact lens care solutions, the obtained solution is suitable for the cleaning, rinsing, disinfection and storage of contact lenses.
  • the invention relates to the use of a bio- degradable detergent in contact lens care solutions.
  • the invention also relates to a contact lens care solution which is characterized in that it contains a biodegradable detergent.
  • the invention further relates to a method for the care of contact lenses. The method is character ⁇ ized by treating the contact lens by a care solution containing a biodegradable detergent.
  • biodegradable detergent any biodegradable detergent can be used.
  • preferred biodegrad ⁇ able detergents include 6-0-alkanoylglucosides, a particularly advantageous group consisting of those of the formula
  • R represents alkyl with 7 to 17 carbon atoms
  • R 1 represents ethyl or propyl.
  • Preferred 6-0- alkanoylglucosides of formula I include ethyl-6-0- octanoylglucoside, ethyl-6-0-decanoylglucoside, ethyl- 6-0-dodecanoylglucoside, ethyl-6-0-tetradecanoyl- glucoside, propyl-6-0-decanoylglucoside and propyl-6- 0-dodecanoylglucoside.
  • One particularly advantageous 6-0-alkanoylglucoside is ethyl-6-0-decanoylglucoside, which is sold by the company Novo Nordisk under the tradename BioSurfTM.
  • a biodegradable detergent can be used in all types of contact lens care solutions. Preferably, however, it is used in care solutions containing biguanide, particularly chlorhexidine acetate.
  • Chlorhexidine is a cationic ⁇ -substituted bibisguanide having a wide anti ⁇ bacterial spectrum.
  • the advantageous effect of a biodegradable detergent, such as ethyl-6-0-decanoyl ⁇ glucoside is attributed to the fact that such a detergent, in addition to its own possible anti ⁇ bacterial effect, improves the antibacterial effect of other substances, such as chlorhexidine.
  • a biodegradable detergent decomposes biofilms, which creates a suitable microenvironment for disinfectants.
  • the amount of the antibacterial agent, such as biguanide, preferably chlorhexidine acetate, in the care solution is preferably between 0.000025 and 0.0025% by weight, most preferably about 0.00025% by weight.
  • the care solution according to the invention may contain conventional additives, such as ethylene-diamine tetraacetic acid (EDTA), and a buffer.
  • EDTA ethylene-diamine tetraacetic acid
  • the care solution according to the invention typically contains 0.001 to 0.1% by weight, preferably about 0.005% by weight, of a biodegradable detergent.
  • a contact lens care solution which contained ion-exchanged water and Chlorhexidine acetate 0.00025% by weight EDTA 0.1% by weight
  • the pH of the solution is adjusted between 7.0 and 8.0 with concentrated hydrochloric acid.
  • Example 2 Chlorhexidine acetate 0.00025% by weight EDTA 0.1% by weight NaCl 0.47% by weight
  • the pH of the solution is adjusted between 7.0 and 8.0 with concentrated hydrochloric acid.
  • Example 3 Chlorhexidine acetate 0.00025% by weight EDTA 0.1% by weight NaCl 0.47% by weight
  • the pH of the solution is adjusted between 7.0 and 8.0 with concentrated hydrochloric acid.
  • the pH of the solution is adjusted between 7.0 and 8.0 with concentrated hydrochloric acid.
  • the pH of the solution is adjusted between 7.0 and 8.0 with concentrated hydrochloric acid.
  • Example 6 Chlorhexidine acetate 0.00025% by weight EDTA 0.1% by weight NaCl 0.47% by weight Na-tetraborate decahydrate 0.14% by weight
  • the pH of the solution is adjusted between 7.0 and 8.0 with concentrated hydrochloric acid.

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Wood Science & Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Detergent Compositions (AREA)
  • Apparatus For Disinfection Or Sterilisation (AREA)
  • Eyeglasses (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

L'invention se rapporte à l'utilisation d'un détergent biodégradable dans des solutions destinées à l'entretien de lentilles de contact. L'invention se rapporte également à une solution d'entretien contenant ce détergent biodégradable, ainsi qu'à un procédé d'entretien de lentilles de contact.
PCT/FI1994/000392 1993-09-24 1994-09-05 Solutions d'entretien de lentilles de contact Ceased WO1995008352A1 (fr)

Priority Applications (3)

Application Number Priority Date Filing Date Title
AU75389/94A AU7538994A (en) 1993-09-24 1994-09-05 Contact lens care solutions
EP94925504A EP0728020A1 (fr) 1993-09-24 1994-09-05 Solutions d'entretien de lentilles de contact
JP7509579A JPH09503134A (ja) 1993-09-24 1994-09-05 コンタクトレンズ保護溶液

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FI934199A FI93609C (fi) 1993-09-24 1993-09-24 Biologisesti hajoavan detergentin käyttö piilolinssien hoitoliuoksissa, hoitoliuos ja menetelmä piilolinssien hoitamiseksi
FI934199 1993-09-24

Publications (1)

Publication Number Publication Date
WO1995008352A1 true WO1995008352A1 (fr) 1995-03-30

Family

ID=8538656

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/FI1994/000392 Ceased WO1995008352A1 (fr) 1993-09-24 1994-09-05 Solutions d'entretien de lentilles de contact

Country Status (6)

Country Link
EP (1) EP0728020A1 (fr)
JP (1) JPH09503134A (fr)
AU (1) AU7538994A (fr)
CA (1) CA2172043A1 (fr)
FI (1) FI93609C (fr)
WO (1) WO1995008352A1 (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2762849A1 (fr) * 1997-05-05 1998-11-06 Essilor Int Solution aqueuse d'entretien des lentilles de contact
CN104138856A (zh) * 2014-07-16 2014-11-12 北京卫星制造厂 一种机构密封圈的在轨擦拭装置及擦拭方法

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0055515A2 (fr) * 1980-12-18 1982-07-07 Smith and Nephew Associated Companies p.l.c. Solutions pour la stérilisation de lentilles et leur utilisation
EP0255041A1 (fr) * 1986-07-31 1988-02-03 Henkel Kommanditgesellschaft auf Aktien Système de désinfection et de nettoyage de lentilles de contact
EP0384666A2 (fr) * 1989-02-21 1990-08-29 BAUSCH & LOMB INCORPORATED Méthode et composition pour le nettoyage et la désinfection de lentilles de contact
EP0423968A1 (fr) * 1989-10-06 1991-04-24 Unilever Plc Composition détergente
WO1992011876A1 (fr) * 1990-12-27 1992-07-23 Schering Corporation Procede et composition de desinfection pour lentilles de contact
WO1992016244A1 (fr) * 1991-03-18 1992-10-01 Allergan, Inc. Compositions de desinfection de lentilles de contact
EP0524150A1 (fr) * 1991-07-19 1993-01-20 Ciba-Geigy Ag Amélioration de solutions désinfectrices de peroxyde d'hydrogène

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0055515A2 (fr) * 1980-12-18 1982-07-07 Smith and Nephew Associated Companies p.l.c. Solutions pour la stérilisation de lentilles et leur utilisation
EP0255041A1 (fr) * 1986-07-31 1988-02-03 Henkel Kommanditgesellschaft auf Aktien Système de désinfection et de nettoyage de lentilles de contact
EP0384666A2 (fr) * 1989-02-21 1990-08-29 BAUSCH & LOMB INCORPORATED Méthode et composition pour le nettoyage et la désinfection de lentilles de contact
EP0423968A1 (fr) * 1989-10-06 1991-04-24 Unilever Plc Composition détergente
WO1992011876A1 (fr) * 1990-12-27 1992-07-23 Schering Corporation Procede et composition de desinfection pour lentilles de contact
WO1992016244A1 (fr) * 1991-03-18 1992-10-01 Allergan, Inc. Compositions de desinfection de lentilles de contact
EP0524150A1 (fr) * 1991-07-19 1993-01-20 Ciba-Geigy Ag Amélioration de solutions désinfectrices de peroxyde d'hydrogène

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
ACTA OPHTHALMOLOGICA, Volume 64, 1986, PER-ARNE PARMENT et al., "Persistance of Serratia Marcescens, Serratia Liquefaciens and E. Coli in Solution for Contact Lenses", page 456 - page 462. *
ARCHIVES OF OPHTHALMOLOGY, Volume 109, August 1991, LOUIS A. WILSON et al., "Comparative Efficacies of Soft Contact Lens Disinfectant Solutions Against Microbial Films in Lens Cases", page 1155 - page 1157. *

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2762849A1 (fr) * 1997-05-05 1998-11-06 Essilor Int Solution aqueuse d'entretien des lentilles de contact
EP0877075A1 (fr) * 1997-05-05 1998-11-11 Essilor International Compagnie Generale D'optique Solution aqueuse d'entretien des lentilles de contact
US6207628B1 (en) 1997-05-05 2001-03-27 Essilor International Compagnie Generale D'optique Aqueous solution
CN104138856A (zh) * 2014-07-16 2014-11-12 北京卫星制造厂 一种机构密封圈的在轨擦拭装置及擦拭方法

Also Published As

Publication number Publication date
FI93609C (fi) 1995-05-10
FI93609B (fi) 1995-01-31
AU7538994A (en) 1995-04-10
FI934199A0 (fi) 1993-09-24
EP0728020A1 (fr) 1996-08-28
JPH09503134A (ja) 1997-03-31
CA2172043A1 (fr) 1995-03-30

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