WO1995009984A1 - Pompe a sang centrifuge dotee d'un aubage formant un cone inducteur de tournoiement du sang - Google Patents

Pompe a sang centrifuge dotee d'un aubage formant un cone inducteur de tournoiement du sang Download PDF

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Publication number
WO1995009984A1
WO1995009984A1 PCT/US1994/010202 US9410202W WO9509984A1 WO 1995009984 A1 WO1995009984 A1 WO 1995009984A1 US 9410202 W US9410202 W US 9410202W WO 9509984 A1 WO9509984 A1 WO 9509984A1
Authority
WO
WIPO (PCT)
Prior art keywords
impeller
spindle
blades
centrifugal pump
inlet
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US1994/010202
Other languages
English (en)
Inventor
Lloyd C. Hubbard
Earl W. Clausen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Haemonetics Corp
Spin Corp
Original Assignee
Haemonetics Corp
Spin Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Haemonetics Corp, Spin Corp filed Critical Haemonetics Corp
Publication of WO1995009984A1 publication Critical patent/WO1995009984A1/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04D—NON-POSITIVE-DISPLACEMENT PUMPS
    • F04D13/00—Pumping installations or systems
    • F04D13/02—Units comprising pumps and their driving means
    • F04D13/021—Units comprising pumps and their driving means containing a coupling
    • F04D13/024—Units comprising pumps and their driving means containing a coupling a magnetic coupling
    • F04D13/026—Details of the bearings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
    • A61M60/10—Location thereof with respect to the patient's body
    • A61M60/104—Extracorporeal pumps, i.e. the blood being pumped outside the patient's body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
    • A61M60/10—Location thereof with respect to the patient's body
    • A61M60/104—Extracorporeal pumps, i.e. the blood being pumped outside the patient's body
    • A61M60/109—Extracorporeal pumps, i.e. the blood being pumped outside the patient's body incorporated within extracorporeal blood circuits or systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
    • A61M60/10—Location thereof with respect to the patient's body
    • A61M60/104—Extracorporeal pumps, i.e. the blood being pumped outside the patient's body
    • A61M60/117—Extracorporeal pumps, i.e. the blood being pumped outside the patient's body for assisting the heart, e.g. transcutaneous or external ventricular assist devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
    • A61M60/20—Type thereof
    • A61M60/205—Non-positive displacement blood pumps
    • A61M60/216—Non-positive displacement blood pumps including a rotating member acting on the blood, e.g. impeller
    • A61M60/226—Non-positive displacement blood pumps including a rotating member acting on the blood, e.g. impeller the blood flow through the rotating member having mainly radial components
    • A61M60/232—Centrifugal pumps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
    • A61M60/30—Medical purposes thereof other than the enhancement of the cardiac output
    • A61M60/36—Medical purposes thereof other than the enhancement of the cardiac output for specific blood treatment; for specific therapy
    • A61M60/38—Blood oxygenation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
    • A61M60/40—Details relating to driving
    • A61M60/403—Details relating to driving for non-positive displacement blood pumps
    • A61M60/419—Details relating to driving for non-positive displacement blood pumps the force acting on the blood contacting member being permanent magnetic, e.g. from a rotating magnetic coupling between driving and driven magnets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
    • A61M60/80—Constructional details other than related to driving
    • A61M60/802—Constructional details other than related to driving of non-positive displacement blood pumps
    • A61M60/804—Impellers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
    • A61M60/80—Constructional details other than related to driving
    • A61M60/802—Constructional details other than related to driving of non-positive displacement blood pumps
    • A61M60/804—Impellers
    • A61M60/806—Vanes or blades
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
    • A61M60/80—Constructional details other than related to driving
    • A61M60/802—Constructional details other than related to driving of non-positive displacement blood pumps
    • A61M60/818—Bearings
    • A61M60/824—Hydrodynamic or fluid film bearings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
    • A61M60/80—Constructional details other than related to driving
    • A61M60/802—Constructional details other than related to driving of non-positive displacement blood pumps
    • A61M60/818—Bearings
    • A61M60/825—Contact bearings, e.g. ball-and-cup or pivot bearings
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04D—NON-POSITIVE-DISPLACEMENT PUMPS
    • F04D29/00—Details, component parts, or accessories
    • F04D29/18—Rotors
    • F04D29/22—Rotors specially for centrifugal pumps
    • F04D29/2261—Rotors specially for centrifugal pumps with special measures
    • F04D29/2277—Rotors specially for centrifugal pumps with special measures for increasing NPSH or dealing with liquids near boiling-point
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04D—NON-POSITIVE-DISPLACEMENT PUMPS
    • F04D29/00—Details, component parts, or accessories
    • F04D29/18—Rotors
    • F04D29/22—Rotors specially for centrifugal pumps
    • F04D29/24—Vanes
    • F04D29/242—Geometry, shape

Definitions

  • the present invention relates to pumps and more particularly to centrifugal blood pumps in which impeller blades are positioned so that hemolysis is minimized.
  • heart-lung machines were capable of taking over the function of the natural heart and lungs for periods of up to several hours, enabling the development of techniques leading to today's extensive practice of open-heart surgery.
  • the first practical mechanical blood pumps used were peristaltic or "roller” pumps.
  • the pumping action of a roller pump derives from the compression of a section of the flexible plastic tubing which carries the blood through the heart-lung machine.
  • a moving roller presses the tubing against a semicircular platen, moving the blood forward in the tubing.
  • the speed of the moving roller and the diameter of the tubing control the rate of blood flow.
  • roller pump was and is simple and reliable, it has two characteristics which can endanger the patient undergoing surgery. First, if flow is inadvertently obstructed, the resulting increase in pressure produced by a roller pump may exceed the bursting strength of the tubing circuit.
  • centrifugal blood pumps began to replace the roller pump as the "heart" of the heart-lung machine.
  • the pumping action of a centrifugal blood pump derives from the rotation of an impdler within a pumping chamber.
  • One impeller design associated with centrifugal blood pumps is a disk-shaped device with multiple blades positioned on a surface. The impeller is rotated about a central axis of rotation by way of a rotational drive source. After the blood enters the pumping chamber via an inlet, it makes contact with the impeller blades and is rotated along with the impeller. The impeller rotates at a predetermined speed so that a required pressure and flow rate is maintained.
  • centrifugal blood pumps are controlled by the rotational speed of the impeller. At operational speeds, excessive pressure cannot be produced. Additionally, the centrifugal forces in the pump form a natural air trap and, with massive introduction of air, deprime and discontinue pumping altogether.
  • the above-mentioned safety features, and the decreased blood damage, or hemolysis, caused by centrifugal blood pumps is now widely recognized and has led to their extensive use for open heart surgery. In the early 1980s it was demonstrated that a mechanical blood pump could be used as a heart-assist pump for patients who could not be separated from the heart-lung machine following surgery. The readily available centrifugal blood pumps were quickly adapted to this situation as well as to the more routine use during heart surgery.
  • a reduction in hemolysis is achieved by positioning a plurality of blades of the impeller adjacent to the spindle which intersects the center and is the axis of rotation of the impeller.
  • This configuration reduces hemolysis because the velocity of the blade tangential to the axis of rotation is at its minimum at the center of the impeller.
  • hemolysis is reduced because the first contact of the blood with the impeller blade occurs at a point where the impeller blades have a relatively low tangential velocity with respect to the axis of rotation. Since the blades of the present invention are positioned adjacent to the center of the impeller, the blood is slowly accelerated from a point of relatively low tangential velocity to a maximum tangential velocity which occurs when the blood reaches the outer blade end.
  • the present invention is a centrifugal pump for pumping biological fluids such as blood.
  • the pump has a housing which defines a pumping chamber.
  • An impeller supported by a spindle, rotates about an axis of rotation located at the center of the impeller.
  • the impeller itself is disposed within the pumping chamber.
  • the pumping chamber has an inlet directed at the center of the impeller and an outlet provided along the periphery of the impeller.
  • the impeller includes a plurality of blades positioned on a first surface. An inner end of each blade is adjacent to the spindle which supports the impeller. A plurality of inner blade ends form a cone-shaped area, or spin inducer, around the circumference of the spindle. The location of the spin inducer near the center of the impeller causes the blood to rotate at a relatively low tangential velocity when it enters the high flow inlet area.
  • the inner ends of the impeller blades which actually form the cone-shaped spin inducer, are positioned at the center of the impeller adjacent the spindle.
  • the velocity of each inner blade end tangential to the axis of rotation is at a minimum.
  • the spin inducer is able to reduce the amount of hemolysis because the first contact of the blood with the impeller is at a point of relatively low tangential velocity.
  • the gradual acceleration decreases the turbulence of the flow within the pumping chamber and results in less hemolysis than in prior art centrifugal pumps.
  • Figure 1 is an exploded perspective view of the present invention.
  • Figure 1 A is a close-up of a full impeller blade.
  • Figure 2 is a cross-sectional side view of the present invention.
  • Figure 3 is a close-up view of the spin inducer shown in the cross-sectional side view of the Figure 2.
  • centrifugal blood pump 10 A preferred embodiment of the present invention is shown as centrifugal blood pump 10 in Figures 1-3.
  • Figure 1 shows that blood pump 10 is composed of three distinct parts: upper enclosure 12, base 14, and impeller 16.
  • Upper enclosure 12 includes inlet 17, journal bearing 18 and plug
  • inlet 17 facilitates attachment of inlet tubing (not shown) from a reservoir/oxygenator or from the patient.
  • Journal bearing 18 and plug 20 are mounted in aperture 24 at the bend in inlet 17.
  • Base 14 includes cylindrical side wall 32, bottom wall 34 and outlet 36.
  • Bottom wall 34 contains aperture 34A in order to receive journal bearing 45.
  • Outlet 36 is a tubular member which extends from cylindrical side wall 32 to free end 38. Ridge 40 facilitates attachment of outlet tubing (not shown) to free end 38.
  • Impeller 16 includes spindle 42, impeller platform 44, full impeller blades 46 and short impeller blades 48. Central circulation hole 50 and spin inducer 52 are also shown.
  • Figure 1A shows a close-up view of full impeller blade 46.
  • Inner blade end 46A and outer blade end 46B are shown.
  • a plurality of inner blade ends 46 A forms spin inducer 52 (shown in Figures 1, 2 and 3).
  • Full impeller blade 46 is approximately four inches in total length.
  • the width of inner blade end 46A which is measured laterally from spindle 42 (not shown) to the end of the blade, is approximately 0.25 inches.
  • the width of outer blade end 46B which is measured vertically from impeller platform 44 (not shown) to the end of the blade, is approximately 0.38 inches.
  • the clearance between inlet 17 and inner blade end 46A is less than the clearance between upper enclosure 12 and outer blade end 46B.
  • FIG. 2 shows a cross sectional view of centrifugal blood pump 10 as it appears assembled.
  • housing 60 formed by upper enclosure 12 and base 14
  • impeller 16 encloses impeller 16.
  • Pumping chamber P is a volume defined by upper enclosure 12, inlet 17, cylindrical side wall 32 and bottom wall 34.
  • Impeller 16 is supported by spindle 42 and rotates about an axis of rotation defined by spindle 42 in a direction indicated by arrow R.
  • An inlet end of spindle 42 is inserted into journal bearing 18 while an opposite end of spindle 42 is received by journal bearing 45.
  • Bottom wall aperture 34A (shown in Figure 1) receives journal bearing 45.
  • Attached to platform 44 are ull impeller blades 46 and short impeller blades 48.
  • Full blades 46 extend across platform 44 and central circulation hole 50 (shown in Figure 1).
  • Short blades 48 have a length approximately half the radius of platform 44. Both full blades 46 and short blades 48 are tapered.
  • Inner blade ends 46A are supported by and positioned adjacent spindle 42 to form cone-shaped spin inducer 52.
  • Platform 44 has positioned on its bottom surface, magnets (not shown), which are coupled with magnets carried by a drive rotor (not shown) positioned below bottom wall 34 of base 14.
  • an electric motor is connected to the rotor in order to rotate the magnets on the bottom of platform 44 which are coupled with the magnets on the rotor.
  • Both magnets on platform 44 and the rotor rotate about the axis of rotation.
  • the magnets on the bottom of platform 44 and the magnets carried by the rotor are coupled together so that the impeller rotates at the same speed as the rotor.
  • the impeller is mounted on a drive shaft which extends outside the pumping chamber to a rotational drive source. As the drive source is activated, the impeller rotates along with the shaft. In either configuration, however, rotational speed adequate to create the required pump pressure and rate of flow of blood must be maintained.
  • spin inducer 52 serves to reduce the impact of the turbulent flow which is normally associated with the inlet area. Specifically, spin inducer 52 acts as a means to slowly accelerate the blood.
  • the tangential velocity of inner blade ends 46A, which form spin inducer 52 is less than the tangential velocity of outer blade ends 46B.
  • Hemolysis is reduced because the relatively slow tangential velocity and acceleration of the blood as it enters inlet 17 and impacts spin inducer 52 causes less blood damage than prior art pumps which do not have a spin inducer.
  • the inlet may be vertical instead of the curved shape shown in Figures 1-3.
  • the spindle is inserted into a journal bearing which is supported by struts which extend from the inlet wall. Similar to the embodiment shown in Figures 1-3, however, the inlet is flared so that the spin inducer may fit inside.

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Mechanical Engineering (AREA)
  • Cardiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Fluid Mechanics (AREA)
  • Geometry (AREA)
  • Emergency Medicine (AREA)
  • External Artificial Organs (AREA)

Abstract

Une pompe centrifuge (10) conçue pour pomper des liquides biologiques tels que du sang comporte un carter définissant une chambre de pompage. Ladite chambre de pompage renferme une roue (16) dotée d'une broche (42) tournant sur un axe et d'une pluralité d'aubes (46) positionnées chacune de sorte que leur extrémité interne soit adjacente à la broche (42). Les extrémités internes des aubes forment un cône (52) inducteur de tournoiement du sang, permettant de réduire l'hémolyse.
PCT/US1994/010202 1993-10-07 1994-09-12 Pompe a sang centrifuge dotee d'un aubage formant un cone inducteur de tournoiement du sang Ceased WO1995009984A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US13356293A 1993-10-07 1993-10-07
US08/133,562 1993-10-07

Publications (1)

Publication Number Publication Date
WO1995009984A1 true WO1995009984A1 (fr) 1995-04-13

Family

ID=22459219

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1994/010202 Ceased WO1995009984A1 (fr) 1993-10-07 1994-09-12 Pompe a sang centrifuge dotee d'un aubage formant un cone inducteur de tournoiement du sang

Country Status (1)

Country Link
WO (1) WO1995009984A1 (fr)

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0760428A1 (fr) * 1995-08-29 1997-03-05 Fujikoki Corporation Pompe de drainage
EP0834326A3 (fr) * 1996-10-02 1998-09-23 JMS Co., Ltd. Turbopompe à sang
EP1617084A1 (fr) * 2004-07-16 2006-01-18 Fujikoki Corporation Pompe de drainage
EP2407188A4 (fr) * 2009-03-09 2012-07-11 Jms Co Ltd Pompe sanguine à turbine
WO2016047331A1 (fr) * 2014-09-24 2016-03-31 テルモ株式会社 Procédé de fabrication de pompe centrifuge
CN107795513A (zh) * 2017-12-12 2018-03-13 无锡市盛源汽车配件厂 设置进水栅防护的汽车水泵叶轮
CN113769258A (zh) * 2021-10-08 2021-12-10 卡迪美科(北京)生物科技有限公司 医用离心泵头

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3487784A (en) * 1967-10-26 1970-01-06 Edson Howard Rafferty Pumps capable of use as heart pumps
US4507048A (en) * 1979-03-16 1985-03-26 Jacques Belenger Centrifugal clinical blood pump
US4984972A (en) * 1989-10-24 1991-01-15 Minnesota Mining And Manufacturing Co. Centrifugal blood pump

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3487784A (en) * 1967-10-26 1970-01-06 Edson Howard Rafferty Pumps capable of use as heart pumps
US4507048A (en) * 1979-03-16 1985-03-26 Jacques Belenger Centrifugal clinical blood pump
US4984972A (en) * 1989-10-24 1991-01-15 Minnesota Mining And Manufacturing Co. Centrifugal blood pump

Cited By (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0760428A1 (fr) * 1995-08-29 1997-03-05 Fujikoki Corporation Pompe de drainage
CN1068936C (zh) * 1995-08-29 2001-07-25 株式会社不二工机 排水泵
EP0834326A3 (fr) * 1996-10-02 1998-09-23 JMS Co., Ltd. Turbopompe à sang
EP1473048A1 (fr) * 1996-10-02 2004-11-03 JMS Co., Ltd. Turbopompe à sang
EP1617084A1 (fr) * 2004-07-16 2006-01-18 Fujikoki Corporation Pompe de drainage
US8814541B2 (en) 2009-03-09 2014-08-26 Jms Co., Ltd. Turbo blood pump
EP2407188A4 (fr) * 2009-03-09 2012-07-11 Jms Co Ltd Pompe sanguine à turbine
WO2016047331A1 (fr) * 2014-09-24 2016-03-31 テルモ株式会社 Procédé de fabrication de pompe centrifuge
JPWO2016047331A1 (ja) * 2014-09-24 2017-04-27 テルモ株式会社 遠心ポンプの製造方法
JP2018028322A (ja) * 2014-09-24 2018-02-22 テルモ株式会社 遠心ポンプの製造方法
US10851802B2 (en) 2014-09-24 2020-12-01 Terumo Kabushiki Kaisha Method of manufacturing centrifugal pump
CN107795513A (zh) * 2017-12-12 2018-03-13 无锡市盛源汽车配件厂 设置进水栅防护的汽车水泵叶轮
CN113769258A (zh) * 2021-10-08 2021-12-10 卡迪美科(北京)生物科技有限公司 医用离心泵头

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