WO1998029006A1 - Brosse a dents a fonction prophylactique - Google Patents

Brosse a dents a fonction prophylactique Download PDF

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Publication number
WO1998029006A1
WO1998029006A1 PCT/CN1997/000053 CN9700053W WO9829006A1 WO 1998029006 A1 WO1998029006 A1 WO 1998029006A1 CN 9700053 W CN9700053 W CN 9700053W WO 9829006 A1 WO9829006 A1 WO 9829006A1
Authority
WO
WIPO (PCT)
Prior art keywords
bristles
toothbrush
sodium
health
fluoride
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/CN1997/000053
Other languages
English (en)
Chinese (zh)
Inventor
Jungang Zhang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to AU29480/97A priority Critical patent/AU2948097A/en
Publication of WO1998029006A1 publication Critical patent/WO1998029006A1/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A46—BRUSHWARE
    • A46D—MANUFACTURE OF BRUSHES
    • A46D1/00—Bristles; Selection of materials for bristles

Definitions

  • the present invention relates to a new type of toothbrush, and more specifically a health toothbrush containing bristles containing compound particles having a role in protecting teeth.
  • Chinese patent application 90101463.X discloses a toothbrush coated with a coating film on the outside of the bristles.
  • the film is composed of a polymer having cation exchange capacity and a cationic fungicide. When a toothbrush is used, it can be released from the film. Out fungicide.
  • Chinese patent application 92109704.2 discloses a continuous release matrix material for dentistry. This material is doped with a germicidal bactericide, and this material is made into a substrate inside the toothbrush, so that the toothbrush can release the germicide in use.
  • Chinese patent application 94106489.1 discloses a method for producing an antibacterial health toothbrush.
  • the bristles contain germicidal substances, so that the toothbrush has the functions of killing bacteria and self-cleaning.
  • the toothbrushes disclosed above are used for sterilization purposes, instead of directly adding fluoride to the toothbrush base material to prevent and treat dental caries.
  • they are also generally unsatisfactory, or the manufacturing process is more complicated, or the production cost is higher, or the use is not easy, or the drug effect is not long-lasting, not obvious, etc., which seriously affects these technologies
  • Popular Application-Chinese Patent Application 94114969.2 discloses an anti-caries toothbrush, which contains bristles Fluoride, a medicine for preventing dental caries, releases fluoride when using a toothbrush by friction between the toothbrush and the teeth.
  • the toothbrush has some effects on preventing dental caries and anti-allergies, because its prescription is too simple, there are still many disadvantages:
  • the present inventors have conducted extensive and in-depth studies in order to develop a health toothbrush that does not have the above-mentioned disadvantages of the prior art, and has the function of preventing caries and protecting teeth while cleaning the teeth. It was found that when bristles are added with compounds that prevent and treat dental diseases such as calcium deficiency and desensitization, and fluorine compounds that have a slow-release effect, these compounds are added according to different water quality, different subjects, and different purposes. When separated with fluorine compounds in different bristles, it can effectively treat early dental caries while preventing dental caries, promote tooth remineralization and prevent and treat other dental diseases, and the drug effect is durable, thus completing the present invention.
  • dental diseases such as calcium deficiency and desensitization, and fluorine compounds that have a slow-release effect
  • the object of the present invention is to provide a health-care toothbrush.
  • the toothbrush has the effects of treating early dental caries, promoting tooth remineralization, and preventing and treating other dental diseases while cleaning and preventing dental caries, and has long-lasting effects.
  • a health toothbrush includes a handle and bristles made of synthetic fiber filaments.
  • the bristles are divided into nail bristles and ethyl bristles.
  • the nail bristles contain fluoride particles, and the ethyl bristles. Contains metal cation compound particles.
  • the fluoride useful in the present invention may be sodium monofluorophosphate, sodium fluoride, stannous fluoride, sodium fluorozirconate, sodium fluoroborate or a mixture thereof, and the metal cation compound useful in the present invention may be lanthanum chloride , Strontium chloride, zinc chloride, calcium chloride, sodium phosphomolybdate or mixtures thereof.
  • Raw materials such as nylon 1010, nylon 610 or other drawing materials.
  • the average particle size of the compound fine particles used in the present invention is not particularly limited as long as it does not affect the drawing of the nylon masterbatch, and is preferably 120 mesh or more. However, if the average particle size is too small, the processing cost will be disadvantageously increased. Therefore, the upper limit of the average particle size should not be too high, preferably 800 mesh or less.
  • the amount of the compound fine particles in the synthetic fiber filament bristles in the present invention preferably accounts for the total weight of the bristles. 1-6wt%. If the amount is less than 1wt%, the effect of preventing caries and teeth will not be fully exerted; if the amount is more than 6wt%, it will affect the drawing of the nylon masterbatch.
  • the bristle material used in the present invention can be manufactured according to the method described in Chinese patent application 94114969.2, that is, the drug is first dried and ground to the required average particle size, and then the ingredients are weighted according to the weight ratio. 20% nylon masterbatch is first mixed with The dried medicines are mixed, thoroughly mixed, and re-granulated by a granulator. Finally, the remaining 80% nylon masterbatch is added to the re-granulated nylon raw material containing the drug, mixed well, and drawn by a wire drawing machine into the special wire for health toothbrushes of the invention.
  • the health toothbrush of the present invention can select the amount of various drugs and the ratio of two types of bristles according to different water quality, different objects and different purposes.
  • the formula when formulating according to the quality of drinking water, the formula is mainly adjusted according to the different fluorine, calcium and other trace elements contained in the water to achieve the required ratio.
  • the formula when it is required to add a large proportion of fluorine and calcium compounds, for hard water quality, due to the high content of calcium and magnesium ions, A larger proportion of fluorine compounds should be added when formulating.
  • the medicine added to the health toothbrush of the present invention is mainly for preventing caries, but at the same time, it can solve the problems of calcium deficiency, anti-allergy, anti-acid, prevention of gum bleeding and anti-inflammatory. Therefore, different formulas are selected according to different objects and different purposes. . For example, for children, there is no desensitization problem, so caries prevention should be the main formula. Fluorine, lanthanum (lanthanum is a drug that increases the hardness and smoothness of the tooth surface) and zinc (zinc is used to prevent plaque formation) Drugs). For workers working in acidic environments (such as monosodium glutamate plants, chemical plants), it mainly solves the problem of acid resistance and desensitization, and the formula highlights strontium, zinc, molybdenum and other compounds.
  • the dosage of each drug in the formula must be appropriately matched according to the different solubility of the drug and the release curve of the drug ion to meet the therapeutic dose and achieve the purpose of long-term sustained release.
  • Sodium fluorozirconate and sodium fluoroborate were chosen because they contain 6 and 4 F — and F — is gradually decomposed when dissolved.
  • the drug itself has a slow release effect, so it is convenient to form a remineralization system in the oral cavity. Desired free F one.
  • the quantity ratio of the two ions must be considered when making the brush, and the quantity ratio of the two bristles must be determined to achieve accurate treatment. effect.
  • the arrangement of the two types of bristles in A and B can be either in clusters, or in rows and columns or in blocks arranged on the surface of the toothbrush. Hair implantation can be performed by using methods and equipment commonly used in the field of brush making.
  • Example 1 children's health toothbrush
  • Zinc chloride 1 wt% The ratio of the number of nail bristles to the number of bristles of the bristle is 80:20, and the brush surface is composed of clusters, thereby preparing a child-type health toothbrush.
  • Example 2 soft water type health toothbrush
  • the soft water health toothbrush was manufactured according to the procedure of Example 1, except that the following medicines were used with nail bristles: Sodium fluoroborate 2.5wt%
  • the hard water health toothbrush was manufactured according to the procedure of Example 1, except that the following medicines were used with nail bristles: Sodium fluoride 0.9wt%
  • the anti-sensitivity health toothbrush was manufactured according to the procedure of Example 1, except that the following medicines were used with nail bristles: sodium fluozirconate 1.5wt%
  • the health toothbrush of the present invention has the following advantages: Drug particles with anti-dental effects are dispersed in the filaments of synthetic fiber filaments. When brushing teeth, drug ions are precipitated under the action of water and mechanical forces. They act on the teeth as if they are forced to be coated with a drug film on the tooth surface, so the effect is excellent. In toothpaste. The formula based on different solubility can ensure the sustained release of the drug, so the toothbrush is valid for more than three months. The health toothbrush is simple and convenient to make and use, low in cost, good in preventing diseases and protecting teeth, and easy to popularize.
  • the purpose of dividing the bristles into two is to form an effective remineralization system, because F- and other metal cations can easily combine to form water-insoluble fluorides such as calcium fluoride, so if you make a bristle you will lose the drug. Role.
  • the medicine is placed in two kinds of bristles, and a remineralization system is formed in the oral cavity only when the tooth is brushed, which effectively solves the problem of dental caries. Therefore, the health toothbrush of the present invention is not only preventable but also treatable. It is another important feature of the present invention to form a systematic and perfect formula by placing medicines for preventing and treating dental diseases in the bristles in a scientific, targeted and orderly manner.

Landscapes

  • Brushes (AREA)
  • Cosmetics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

L'invention concerne une brosse à dents à fonction prophylactique, comprenant un manche et des poils de filaments de fibre synthétique. Lesdits poils sont classés en deux catégories, dont une contient des particules de fluorure et l'autre contient des particules composées de cations métalliques. La brosse à dents peut prévenir avec efficacité les caries et peut en outre s'adapter aux différentes qualités de l'eau, ainsi que répondre aux besoins spécifiques.
PCT/CN1997/000053 1996-12-30 1997-05-30 Brosse a dents a fonction prophylactique Ceased WO1998029006A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU29480/97A AU2948097A (en) 1996-12-30 1997-05-30 Health toothbrush

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN 96114293 CN1064226C (zh) 1996-12-30 1996-12-30 护齿牙刷
CN96114293.6 1996-12-30

Publications (1)

Publication Number Publication Date
WO1998029006A1 true WO1998029006A1 (fr) 1998-07-09

Family

ID=5122058

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/CN1997/000053 Ceased WO1998029006A1 (fr) 1996-12-30 1997-05-30 Brosse a dents a fonction prophylactique

Country Status (3)

Country Link
CN (1) CN1064226C (fr)
AU (1) AU2948097A (fr)
WO (1) WO1998029006A1 (fr)

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3613143A (en) * 1970-11-12 1971-10-19 Indiana University Foundation Brush with abrasive-impregnated bristles
CN1046091A (zh) * 1989-03-14 1990-10-17 新时代株式会社 牙刷
WO1995001788A1 (fr) * 1993-07-09 1995-01-19 Trustees Of Tufts College Procedes et articles d'administration de medicament dans la cavite buccale
TW254975B (en) * 1995-02-21 1995-08-21 Shyh-Lih Shy A toothbrush with cavity-prevention performance and the production process for its brush hair
CN1108074A (zh) * 1994-08-23 1995-09-13 孟筱玲 防龋药物牙刷
CN1113973A (zh) * 1994-06-24 1995-12-27 温一林 一种抗菌保健牙刷的生产方法

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3613143A (en) * 1970-11-12 1971-10-19 Indiana University Foundation Brush with abrasive-impregnated bristles
CN1046091A (zh) * 1989-03-14 1990-10-17 新时代株式会社 牙刷
WO1995001788A1 (fr) * 1993-07-09 1995-01-19 Trustees Of Tufts College Procedes et articles d'administration de medicament dans la cavite buccale
CN1113973A (zh) * 1994-06-24 1995-12-27 温一林 一种抗菌保健牙刷的生产方法
CN1108074A (zh) * 1994-08-23 1995-09-13 孟筱玲 防龋药物牙刷
TW254975B (en) * 1995-02-21 1995-08-21 Shyh-Lih Shy A toothbrush with cavity-prevention performance and the production process for its brush hair

Also Published As

Publication number Publication date
CN1160521A (zh) 1997-10-01
CN1064226C (zh) 2001-04-11
AU2948097A (en) 1998-07-31

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