WO2000008463A3 - Immunoadsorbant permettant d'eliminer des endotoxines de liquides, procede de preparation et d'utilisation dudit immunoadsorbant - Google Patents

Immunoadsorbant permettant d'eliminer des endotoxines de liquides, procede de preparation et d'utilisation dudit immunoadsorbant Download PDF

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Publication number
WO2000008463A3
WO2000008463A3 PCT/DE1999/002486 DE9902486W WO0008463A3 WO 2000008463 A3 WO2000008463 A3 WO 2000008463A3 DE 9902486 W DE9902486 W DE 9902486W WO 0008463 A3 WO0008463 A3 WO 0008463A3
Authority
WO
WIPO (PCT)
Prior art keywords
immunoadsorber
fluids
research
endotoxins
biomedical
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/DE1999/002486
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German (de)
English (en)
Other versions
WO2000008463A2 (fr
Inventor
Hans-Werner Heinrich
Udo Meyer
Andreas Hlinak
Peter Kruschke
Mirko Sasse
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Privates Institut Bioserv GmbH
Original Assignee
Privates Institut Bioserv GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Privates Institut Bioserv GmbH filed Critical Privates Institut Bioserv GmbH
Priority to AU64632/99A priority Critical patent/AU6463299A/en
Publication of WO2000008463A2 publication Critical patent/WO2000008463A2/fr
Publication of WO2000008463A3 publication Critical patent/WO2000008463A3/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/12—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1203—Gram-negative bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/10—Immunoglobulins specific features characterized by their source of isolation or production
    • C07K2317/11—Immunoglobulins specific features characterized by their source of isolation or production isolated from eggs
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/23—Immunoglobulins specific features characterized by taxonomic origin from birds

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • External Artificial Organs (AREA)

Abstract

Immunoadsorbant permettant d'éliminer spécifiquement des endotoxines bactériennes de liquides, de solutions aqueuses, cristallines et/ou colloïdales, d'émulsions et de liquides corporels (tels que par exemple le sang, le plasma, la lymphe, le liquide céphalo-rachidien) et/ou de liquides obtenus à partir de liquides corporels (tels que par exemple le sérum ou le dialysat). Les endotoxines sont liées (in vitro, ex vivo ou in situ) à des anticorps anti-endotoxines aviaires et donc éliminés du liquide. Un procédé de préparation dudit immunoadsorbant est également décrit. La présente invention peut être utilisée dans les domaines suivants: médecine, médecine vétérinaire, techniques biomédicales, médecine dentaire, pharmacie, recherche biologique, pharmaceutique et médicale, fabrication des denrées alimentaires et éventuellement environnement.
PCT/DE1999/002486 1998-08-05 1999-08-05 Immunoadsorbant permettant d'eliminer des endotoxines de liquides, procede de preparation et d'utilisation dudit immunoadsorbant Ceased WO2000008463A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU64632/99A AU6463299A (en) 1998-08-05 1999-08-05 Immunoadsorber for removing endotoxins from fluids, method for the production and use thereof

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19839429 1998-08-05
DE19839429.2 1998-08-05

Publications (2)

Publication Number Publication Date
WO2000008463A2 WO2000008463A2 (fr) 2000-02-17
WO2000008463A3 true WO2000008463A3 (fr) 2000-04-20

Family

ID=7879178

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/DE1999/002486 Ceased WO2000008463A2 (fr) 1998-08-05 1999-08-05 Immunoadsorbant permettant d'eliminer des endotoxines de liquides, procede de preparation et d'utilisation dudit immunoadsorbant

Country Status (3)

Country Link
AU (1) AU6463299A (fr)
DE (1) DE19938394A1 (fr)
WO (1) WO2000008463A2 (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL165390A0 (en) 2002-06-24 2006-01-15 Profos Ag Methods for identifying and extracting endotoxin
DE10258944A1 (de) 2002-12-17 2004-07-01 B. Braun Medizintechnologie Gmbh Vorrichtung zur Entfernung von bakteriellen Lipopolysacchariden oder/und Lipoteichonsäuren aus proteinhaltigen Flüssigkeiten sowie deren Verwendung zur Behandlung von Sepsis
DE502004003217D1 (de) * 2004-06-03 2007-04-26 Braun Medizintechnologie Gmbh Vorrichtung zur Entfernung von bakteriellen Lipopolysacchariden oder/und Lipoteichonsäuren aus proteinhaltigen Flüssigkeiten sowie Verwendung zur Herstellung eines Mittels zur Entfernung dieser Stoffe
DE102005002969A1 (de) 2005-01-21 2006-08-03 Profos Ag Verfahren zum Nachweis und zur Entfernung von Endotoxin
RU2395304C1 (ru) * 2009-05-25 2010-07-27 Сергей Викторович Кемеров Способ детоксикации организма при критических эндотоксикозах
RU2489172C1 (ru) * 2012-06-22 2013-08-10 Дятленко Оксана Валерьевна Способ проведения лечебного дискретного плазмафереза с экстракарпоральной модификацией эритроцитов и лейкоцитов индукторами интерферона, антиоксидантами и протекторами клеток
EP3477300A1 (fr) 2017-10-25 2019-05-01 Euroimmun Medizinische Labordiagnostika AG Immunoadsorbant à base de cellulose
US12433985B2 (en) 2019-09-30 2025-10-07 Hemotune Ag Assembly for extracorporeal treatment of body fluids

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4113602A1 (de) * 1991-04-23 1992-10-29 Falkenhagen Dieter Dr Sc Med Endotoxinadsorber und verfahren zu seiner herstellung
JPH0634633A (ja) * 1992-07-14 1994-02-10 Toyobo Co Ltd 鶏卵抗体固定化担体およびその製造方法
DE19653669A1 (de) * 1996-12-13 1998-06-18 Affina Immuntechnik Gmbh Adsorptionsmatrix, ihre Herstellung und ihre Verwendung zur Entfernung von Immunglobulinen aus biologischen Flüssigkeiten

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4113602A1 (de) * 1991-04-23 1992-10-29 Falkenhagen Dieter Dr Sc Med Endotoxinadsorber und verfahren zu seiner herstellung
JPH0634633A (ja) * 1992-07-14 1994-02-10 Toyobo Co Ltd 鶏卵抗体固定化担体およびその製造方法
DE19653669A1 (de) * 1996-12-13 1998-06-18 Affina Immuntechnik Gmbh Adsorptionsmatrix, ihre Herstellung und ihre Verwendung zur Entfernung von Immunglobulinen aus biologischen Flüssigkeiten

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
CHEMICAL ABSTRACTS, vol. 120, no. 19, 9 May 1994, Columbus, Ohio, US; abstract no. 239646, XP002129937 *
PATENT ABSTRACTS OF JAPAN vol. 18, no. 253 (P - 1737) 10 February 1994 (1994-02-10) *

Also Published As

Publication number Publication date
WO2000008463A2 (fr) 2000-02-17
DE19938394A1 (de) 2000-02-24
AU6463299A (en) 2000-02-28

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