WO2000008464A3 - Verfahren zur bestimmung der immunabwehr des blutes sowie testkit hierfür - Google Patents

Verfahren zur bestimmung der immunabwehr des blutes sowie testkit hierfür Download PDF

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Publication number
WO2000008464A3
WO2000008464A3 PCT/EP1999/005635 EP9905635W WO0008464A3 WO 2000008464 A3 WO2000008464 A3 WO 2000008464A3 EP 9905635 W EP9905635 W EP 9905635W WO 0008464 A3 WO0008464 A3 WO 0008464A3
Authority
WO
WIPO (PCT)
Prior art keywords
blood
determining
test kit
kit therefor
immune defences
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/EP1999/005635
Other languages
English (en)
French (fr)
Other versions
WO2000008464A2 (de
Inventor
Manfred Schmolz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
EDI Experimentelle und Diagnostische Immunologie GmbH
Original Assignee
EDI Experimentelle und Diagnostische Immunologie GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by EDI Experimentelle und Diagnostische Immunologie GmbH filed Critical EDI Experimentelle und Diagnostische Immunologie GmbH
Priority to DE59912716T priority Critical patent/DE59912716D1/de
Priority to US09/762,189 priority patent/US6410334B1/en
Priority to EP99940137A priority patent/EP1102988B8/de
Priority to AU54193/99A priority patent/AU5419399A/en
Priority to AT99940137T priority patent/ATE308045T1/de
Publication of WO2000008464A2 publication Critical patent/WO2000008464A2/de
Publication of WO2000008464A3 publication Critical patent/WO2000008464A3/de
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/49—Blood
    • G01N33/491—Blood by separating the blood components
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Ecology (AREA)
  • Biophysics (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

Die Erfindung betrifft ein Verfahren zur Bestimmung der Immunabwehraktivität von Blut durch Stimulation der weißen Blutzellen im Vollblut, Inkubieren des Vollblutes, Trennung von Überstand vom Sediment und Bestimmung der Aktivität aus dem abgetrennten Überstand. Die Erfindung betrifft ferner einen Testkit für die Durchführung des Verfahrens sowie die Verwendung eines geeigneten Blutentnahmesystems, insbesondere eines Spritzenzylinders, hierzu.
PCT/EP1999/005635 1998-08-07 1999-08-04 Verfahren zur bestimmung der immunabwehr des blutes sowie testkit hierfür Ceased WO2000008464A2 (de)

Priority Applications (5)

Application Number Priority Date Filing Date Title
DE59912716T DE59912716D1 (de) 1998-08-07 1999-08-04 Verfahren zur bestimmung der immunabwehraktivität des blutes sowie testkit hierfür
US09/762,189 US6410334B1 (en) 1998-08-07 1999-08-04 Method for determining the immune defense of blood and test kit for the same and use of a suitable blood sampling system
EP99940137A EP1102988B8 (de) 1998-08-07 1999-08-04 Verfahren zur bestimmung der immunabwehraktivität des blutes sowie testkit hierfür
AU54193/99A AU5419399A (en) 1998-08-07 1999-08-04 Method for determining the immune defences of blood, test kit therefor and use of a suitable system for taking blood samples
AT99940137T ATE308045T1 (de) 1998-08-07 1999-08-04 Verfahren zur bestimmung der immunabwehraktivität des blutes sowie testkit hierfür

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19835721A DE19835721A1 (de) 1998-08-07 1998-08-07 Verfahren zur Bestimmung der Immunabwehr des Blutes sowie Testkit hierfür und Verwendung eines geeigneten Spritzenzylinders
DE19835721.4 1998-08-07

Publications (2)

Publication Number Publication Date
WO2000008464A2 WO2000008464A2 (de) 2000-02-17
WO2000008464A3 true WO2000008464A3 (de) 2000-06-22

Family

ID=7876778

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP1999/005635 Ceased WO2000008464A2 (de) 1998-08-07 1999-08-04 Verfahren zur bestimmung der immunabwehr des blutes sowie testkit hierfür

Country Status (6)

Country Link
US (1) US6410334B1 (de)
EP (1) EP1102988B8 (de)
AT (1) ATE308045T1 (de)
AU (1) AU5419399A (de)
DE (2) DE19835721A1 (de)
WO (1) WO2000008464A2 (de)

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AT500247B1 (de) 2001-03-30 2007-06-15 Greiner Bio One Gmbh Aufnahmeeinrichtung, insbesondere für körperflüssigkeiten, mit einer trennvorrichtung sowie trennvorrichtung hierzu
US20030205538A1 (en) 2002-05-03 2003-11-06 Randel Dorian Methods and apparatus for isolating platelets from blood
US7832566B2 (en) 2002-05-24 2010-11-16 Biomet Biologics, Llc Method and apparatus for separating and concentrating a component from a multi-component material including macroparticles
US7845499B2 (en) 2002-05-24 2010-12-07 Biomet Biologics, Llc Apparatus and method for separating and concentrating fluids containing multiple components
WO2003099412A1 (en) * 2002-05-24 2003-12-04 Biomet Manufacturing Corp. Apparatus and method for separating and concentrating fluids containing multiple components
AU2002952548A0 (en) * 2002-11-08 2002-11-21 Cellestis Limited Diagnostic assay
DE10340613A1 (de) * 2003-08-29 2005-03-24 Primojex Gmbh Vorrichtung zur Injektion eines injizierbaren Produktes
US20050266398A1 (en) * 2004-06-01 2005-12-01 Peter Lea Method and device for rapid detection and quantitation of macro and micro matrices
US20080300173A1 (en) * 2004-07-13 2008-12-04 Defrees Shawn Branched Peg Remodeling and Glycosylation of Glucagon-Like Peptides-1 [Glp-1]
CA2474940A1 (en) * 2004-07-16 2006-01-16 Peter Lea Method and device to process, label and concentrate analytes
CA2475456A1 (en) 2004-07-20 2006-01-20 Biophys, Inc. Method and device to optimize analyte and antibody substrate binding by least energy adsorption
CA2475191A1 (en) * 2004-07-20 2006-01-20 Biophys, Inc. System and method for rapid reading of macro and micro matrices
CA2475240A1 (en) * 2004-07-20 2006-01-20 Biophys, Inc. Method and device to measure dynamic internal calibration true dose response curves
CA2569971A1 (en) * 2006-12-04 2008-06-04 Umedik Inc. Method for double-dip substrate spin optimization of coated micro array supports
US8382704B2 (en) 2006-12-29 2013-02-26 Medrad, Inc. Systems and methods of delivering a dilated slurry to a patient
US20100093551A1 (en) * 2008-10-09 2010-04-15 Decision Biomarkers, Inc. Liquid Transfer and Filter System
WO2010138895A2 (en) 2009-05-29 2010-12-02 Neil Francis Duffy Apparatus and methods for aspirating and separating components of different densities from a physiological fluid containing cells
US7927563B1 (en) * 2009-10-13 2011-04-19 Cytomedix, Inc. Kit for separation of biological fluids
US9427707B2 (en) 2012-08-10 2016-08-30 Jean I. Montagu Filtering blood
WO2014120797A1 (en) 2013-01-29 2014-08-07 Endocellutions, Inc. Cell concentration devices and methods
US10550419B2 (en) * 2013-03-13 2020-02-04 Heidi Kay Utilities of stimulated whole blood culture systems
WO2016183434A1 (en) * 2015-05-14 2016-11-17 Becton, Dickinson And Company Blood culture system with low media volume
DE102019214137A1 (de) * 2019-09-17 2021-03-18 Hot Screen Gmbh Verwendung in vitro eines Kits und eines Verfahrens zur Diagnostik von Transplantationen und/oder Autoimmunerkrankungen und/oder Tumorerkrankungen und/oder Vakzinierungen sowie ein botenstoffhaltiger Überstand, zellhaltiges Sediment und eine Kombination zur Anwendung bei der Diagnostik von Transplantationen und/oder Autoimmunerkrankungen und/oder Tumorerkrankungen und/oder Vakzinierungen
WO2021231504A1 (en) * 2020-05-12 2021-11-18 Rpi Consulting Llc Systems and methods for isolating and testing blood for biomarkers and genetic material

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DE4128923A1 (de) * 1990-10-05 1992-04-09 Sarstedt Walter Geraete Trennvorrichtung fuer fluessigkeits-, insbesondere blutfraktionen
US5128270A (en) * 1987-05-19 1992-07-07 Ire-Medgenix S.A. Assay of monokines

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Publication number Priority date Publication date Assignee Title
DE2948653C2 (de) 1979-12-04 1984-01-05 Walter Sarstedt Kunststoff-Spritzgußwerk, 5223 Nümbrecht Blutentnahmevorrichtung
DE3049503C2 (de) 1980-12-30 1983-04-28 Walter Sarstedt Kunststoff-Spritzgußwerk, 5223 Nümbrecht "Blutentnahmevorrichtung"
US4615341A (en) * 1981-06-18 1986-10-07 Syringe Industries, Inc. Syringe device for physiological fluid sampling
US4745058A (en) * 1984-05-10 1988-05-17 Townsley Philip M Method for producing cellulosic fibers and microcrystalline cellulose
DE3542331C2 (de) * 1985-11-29 1995-07-06 Sarstedt Kunststoff Filtervorrichtung für Flüssigkeiten
CA1299099C (en) 1986-03-06 1992-04-21 Paul Richard Wood In vitro assay for detecting cell-mediated immune responses
EP0294216A3 (de) * 1987-06-05 1990-05-30 Interferon Sciences, Inc. Funktionelle Prüfung für t-Lymphozyten
CA2003455C (en) * 1988-11-23 2000-02-22 Craig B. Thompson Immunotherapy involving cd28 stimulation
GB2232599A (en) * 1989-06-08 1990-12-19 Summers Dr Julie Andrea One-step blood to plasma device
DE19620443C2 (de) * 1996-05-21 1998-09-17 Rhein Biotech Proz & Prod Gmbh Verfahren zum automatischen Durchführen von Bluttests

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5128270A (en) * 1987-05-19 1992-07-07 Ire-Medgenix S.A. Assay of monokines
DE4128923A1 (de) * 1990-10-05 1992-04-09 Sarstedt Walter Geraete Trennvorrichtung fuer fluessigkeits-, insbesondere blutfraktionen

Also Published As

Publication number Publication date
EP1102988B1 (de) 2005-10-26
EP1102988A2 (de) 2001-05-30
EP1102988B8 (de) 2006-06-14
AU5419399A (en) 2000-02-28
DE19835721A1 (de) 2000-02-10
WO2000008464A2 (de) 2000-02-17
DE59912716D1 (de) 2005-12-01
ATE308045T1 (de) 2005-11-15
US6410334B1 (en) 2002-06-25

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