WO2001000192A3 - Procede d'administration d'un derive d'imidazole pour obtenir une analgesie - Google Patents

Procede d'administration d'un derive d'imidazole pour obtenir une analgesie Download PDF

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Publication number
WO2001000192A3
WO2001000192A3 PCT/FI2000/000566 FI0000566W WO0100192A3 WO 2001000192 A3 WO2001000192 A3 WO 2001000192A3 FI 0000566 W FI0000566 W FI 0000566W WO 0100192 A3 WO0100192 A3 WO 0100192A3
Authority
WO
WIPO (PCT)
Prior art keywords
administering
imidazole derivative
intraspinally
analgesia
obtain analgesia
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/FI2000/000566
Other languages
English (en)
Other versions
WO2001000192A2 (fr
Inventor
Antti Haapalinna
Jyrki Lehtimaeki
Tiina Leino
Timo Viitamaa
Raimo Virtanen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Orion Oyj
Original Assignee
Orion Oyj
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Orion Oyj filed Critical Orion Oyj
Priority to AU55378/00A priority Critical patent/AU5537800A/en
Priority to EP00940441A priority patent/EP1196168A2/fr
Publication of WO2001000192A2 publication Critical patent/WO2001000192A2/fr
Publication of WO2001000192A3 publication Critical patent/WO2001000192A3/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4174—Arylalkylimidazoles, e.g. oxymetazolin, naphazoline, miconazole

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

La présente invention concerne une méthode d'obtention d'analgésie par administration de 3-[1-(1H-imidazol-4-yl)-éthyl]-indan-5-ol, son énantiomère ou son ester ou sel acceptable sur le plan pharmaceutique à un mammifère par voie intraspinale. Le 3-[1-(1H-imidazol-4-yl)-éthyl]-indan-5-ol, son énantiomère ou son sel ou ester acceptable sur le plan pharmaceutique peuvent être administrés par voie intraspinale à un mammifère recevant une analgésie sans effet secondaire, telle que la sédation. La présente invention concerne également une méthode d'utilisation du médicament en tant qu'appoint de l'anesthésie par administration par voie intraspinale.
PCT/FI2000/000566 1999-06-25 2000-06-22 Procede d'administration d'un derive d'imidazole pour obtenir une analgesie Ceased WO2001000192A2 (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
AU55378/00A AU5537800A (en) 1999-06-25 2000-06-22 Method of admistering an imidazole derivative to obtain analgesia
EP00940441A EP1196168A2 (fr) 1999-06-25 2000-06-22 Procede d'administration d'un derive d'imidazole pour obtenir une analgesie

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US14079599P 1999-06-25 1999-06-25
US60/140,795 1999-06-25

Publications (2)

Publication Number Publication Date
WO2001000192A2 WO2001000192A2 (fr) 2001-01-04
WO2001000192A3 true WO2001000192A3 (fr) 2001-06-07

Family

ID=22492822

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/FI2000/000566 Ceased WO2001000192A2 (fr) 1999-06-25 2000-06-22 Procede d'administration d'un derive d'imidazole pour obtenir une analgesie

Country Status (3)

Country Link
EP (1) EP1196168A2 (fr)
AU (1) AU5537800A (fr)
WO (1) WO2001000192A2 (fr)

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0424059A1 (fr) * 1989-10-17 1991-04-24 Orion-Yhtymà„ Oy Utilisation d'imidazoles substituées pour la fabrication d'un analgésique
WO1997012874A1 (fr) * 1995-10-03 1997-04-10 Orion-Yhtymä Oy Derives d'imidazole a affinite pour l'activite de recepteurs alpha2
US5801188A (en) * 1997-01-08 1998-09-01 Medtronic Inc. Clonidine therapy enhancement
WO2000018400A1 (fr) * 1998-09-28 2000-04-06 Orion Corporation Utilisation de 3-(1h-imidazol-4-ylmethyl)-indan-5-ol dans la fabrication d'un medicament s'administrant par voie sous-arachnoidienne, intrathecale ou peridurale

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0424059A1 (fr) * 1989-10-17 1991-04-24 Orion-Yhtymà„ Oy Utilisation d'imidazoles substituées pour la fabrication d'un analgésique
WO1997012874A1 (fr) * 1995-10-03 1997-04-10 Orion-Yhtymä Oy Derives d'imidazole a affinite pour l'activite de recepteurs alpha2
US5801188A (en) * 1997-01-08 1998-09-01 Medtronic Inc. Clonidine therapy enhancement
WO2000018400A1 (fr) * 1998-09-28 2000-04-06 Orion Corporation Utilisation de 3-(1h-imidazol-4-ylmethyl)-indan-5-ol dans la fabrication d'un medicament s'administrant par voie sous-arachnoidienne, intrathecale ou peridurale

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
EISENACH J C ET AL: "Antinociceptive and hemodynamic effects of a novel alpha2-adrenergic agonist, MPV-2426, in sheep", ANESTHESIOLOGY, vol. 91, no. 5, November 1999 (1999-11-01), pages 1425 - 1436, XP002901419 *

Also Published As

Publication number Publication date
EP1196168A2 (fr) 2002-04-17
AU5537800A (en) 2001-01-31
WO2001000192A2 (fr) 2001-01-04

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