WO2001051633A3 - Compositions et methodes destinees au traitement et au diagnostique du cancer de la prostate - Google Patents

Compositions et methodes destinees au traitement et au diagnostique du cancer de la prostate Download PDF

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Publication number
WO2001051633A3
WO2001051633A3 PCT/US2001/001574 US0101574W WO0151633A3 WO 2001051633 A3 WO2001051633 A3 WO 2001051633A3 US 0101574 W US0101574 W US 0101574W WO 0151633 A3 WO0151633 A3 WO 0151633A3
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WO
WIPO (PCT)
Prior art keywords
compositions
diagnosis
prostate cancer
therapy
methods
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2001/001574
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English (en)
Other versions
WO2001051633A9 (fr
WO2001051633A2 (fr
Inventor
Jiangchun Xu
Davin C Dillon
Jennifer L Mitcham
Susan L Harlocker
Yuqiu Jiang
Steven G Reed
Michael D Kalos
Gary Richard Fanger
Craig H Day
Marc W Retter
John A Stolk
Yasir A W Skeiky
Aijun Wang
Madeleine Joy Meagher
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Corixa Corp
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Corixa Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to JP2001551207A priority Critical patent/JP2003528591A/ja
Priority to HU0203968A priority patent/HUP0203968A3/hu
Priority to MXPA02006934A priority patent/MXPA02006934A/es
Priority to CA002397741A priority patent/CA2397741A1/fr
Priority to BR0107643-4A priority patent/BR0107643A/pt
Priority to AU34474/01A priority patent/AU3447401A/en
Priority to IL15073201A priority patent/IL150732A0/xx
Priority to EP01906582A priority patent/EP1261708A2/fr
Application filed by Corixa Corp filed Critical Corixa Corp
Publication of WO2001051633A2 publication Critical patent/WO2001051633A2/fr
Publication of WO2001051633A3 publication Critical patent/WO2001051633A3/fr
Anticipated expiration legal-status Critical
Priority to NO20023402A priority patent/NO20023402L/no
Publication of WO2001051633A9 publication Critical patent/WO2001051633A9/fr
Ceased legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/10—Cellular immunotherapy characterised by the cell type used
    • A61K40/11—T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/30—Cellular immunotherapy characterised by the recombinant expression of specific molecules in the cells of the immune system
    • A61K40/32—T-cell receptors [TCR]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
    • A61K40/41—Vertebrate antigens
    • A61K40/42—Cancer antigens
    • A61K40/4274—Prostate associated antigens e.g. Prostate stem cell antigen [PSCA]; Prostate carcinoma tumor antigen [PCTA]; Prostatic acid phosphatase [PAP]; Prostate-specific G-protein-coupled receptor [PSGR]
    • A61K40/4275—Prostate specific antigen [PSA]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53—DNA (RNA) vaccination
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/16011—Orthomyxoviridae
    • C12N2760/16022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Virology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

L'invention concerne des compositions et des méthodes destinées au traitement et au diagnostique de cancer, plus précisément le cancer de la prostate. Ces compositions comprennent un ou plusieurs polypeptides spécifiques de la prostate, des portions immunogéniques de ces polypeptides, des polynucléotides codant pour ces polypeptides, une cellule présentant un antigène qui exprime ces polypeptides, et des cellules T qui sont spécifiques des cellules exprimant ces polypetides. Les compositions selon l'invention conviennent, par exemple, pour le diagnostique, la prévention et/ou le traitement de maladies, notamment le cancer de la prostate.
PCT/US2001/001574 2000-01-14 2001-01-16 Compositions et methodes destinees au traitement et au diagnostique du cancer de la prostate Ceased WO2001051633A2 (fr)

Priority Applications (9)

Application Number Priority Date Filing Date Title
IL15073201A IL150732A0 (en) 2000-01-14 2001-01-16 Prostate specific polypeptides, polynucleotides that encode said polypeptides and pharmaceutical compositions containing the same
MXPA02006934A MXPA02006934A (es) 2000-01-14 2001-01-16 Composiciones y metodos para la terapia y diagnostico de cancer de prostata.
CA002397741A CA2397741A1 (fr) 2000-01-14 2001-01-16 Compositions et methodes destinees au traitement et au diagnostique du cancer de la prostate
BR0107643-4A BR0107643A (pt) 2000-01-14 2001-01-16 Composições e processos para a terapia e diagnóstico de c ncer de próstata
AU34474/01A AU3447401A (en) 2000-01-14 2001-01-16 Compositions and methods for the therapy and diagnosis of prostate cancer
JP2001551207A JP2003528591A (ja) 2000-01-14 2001-01-16 前立腺癌の治療及び診断のための組成物及び方法
HU0203968A HUP0203968A3 (en) 2000-01-14 2001-01-16 Compositions and methods for the therapy and diagnosis of prostate cancer
EP01906582A EP1261708A2 (fr) 2000-01-14 2001-01-16 Compositions et methodes destinees au traitement et au diagnostique du cancer de la prostate
NO20023402A NO20023402L (no) 2000-01-14 2002-07-15 Blandinger og fremgangsmåter for behandling og diagnose av prostatakreft

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US48367200A 2000-01-14 2000-01-14
US09/483,672 2000-01-14

Publications (3)

Publication Number Publication Date
WO2001051633A2 WO2001051633A2 (fr) 2001-07-19
WO2001051633A3 true WO2001051633A3 (fr) 2002-06-20
WO2001051633A9 WO2001051633A9 (fr) 2002-10-31

Family

ID=23921037

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/001574 Ceased WO2001051633A2 (fr) 2000-01-14 2001-01-16 Compositions et methodes destinees au traitement et au diagnostique du cancer de la prostate

Country Status (16)

Country Link
EP (1) EP1261708A2 (fr)
JP (1) JP2003528591A (fr)
KR (1) KR20030016217A (fr)
CN (1) CN1436234A (fr)
AU (1) AU3447401A (fr)
BR (1) BR0107643A (fr)
CA (1) CA2397741A1 (fr)
CZ (1) CZ20022756A3 (fr)
HU (1) HUP0203968A3 (fr)
IL (1) IL150732A0 (fr)
MX (1) MXPA02006934A (fr)
NO (1) NO20023402L (fr)
PL (1) PL356908A1 (fr)
RU (1) RU2002121771A (fr)
WO (1) WO2001051633A2 (fr)
ZA (1) ZA200206400B (fr)

Cited By (3)

* Cited by examiner, † Cited by third party
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US9096907B2 (en) 2004-12-24 2015-08-04 Stichting Katholieke Universiteit, The University Medical Centre Nijmegen Prostate cancer prognostic compositions and kits
US9617346B2 (en) 2004-04-22 2017-04-11 Agensys, Inc. Antibodies and molecules derived therefrom that bind to STEAP-1 proteins
US11180571B2 (en) 2017-04-03 2021-11-23 Hoffmann-La Roche Inc. Antibodies binding to STEAP-1

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US20030125536A1 (en) * 1996-01-11 2003-07-03 Corixa Corporation Compositions and methods for the therapy and diagnosis of breast cancer
US7241876B2 (en) 1996-01-11 2007-07-10 Corixa Corporation Compositions and methods for the therapy and diagnosis of breast cancer
US6818751B1 (en) 1997-08-01 2004-11-16 Corixa Corporation Compositions and methods for the therapy and diagnosis of prostate cancer
US7517952B1 (en) 1997-02-25 2009-04-14 Corixa Corporation Compositions and methods for the therapy and diagnosis of prostate cancer
US7202342B1 (en) 1999-11-12 2007-04-10 Corixa Corporation Compositions and methods for the therapy and diagnosis of prostate cancer
US6630305B1 (en) 1999-11-12 2003-10-07 Corixa Corporation Compositions and methods for the therapy and diagnosis of prostate cancer
US6620922B1 (en) 1997-02-25 2003-09-16 Corixa Corporation Compositions and methods for the therapy and diagnosis of prostate cancer
US6613872B1 (en) 1997-02-25 2003-09-02 Corixa Corporation Compounds for immunotherapy of prostate cancer and methods for their use
US6800746B2 (en) 1997-02-25 2004-10-05 Corixa Corporation Compositions and methods for the therapy and diagnosis of prostate cancer
US6465611B1 (en) 1997-02-25 2002-10-15 Corixa Corporation Compounds for immunotherapy of prostate cancer and methods for their use
US6943236B2 (en) 1997-02-25 2005-09-13 Corixa Corporation Compositions and methods for the therapy and diagnosis of prostate cancer
US6759515B1 (en) 1997-02-25 2004-07-06 Corixa Corporation Compositions and methods for the therapy and diagnosis of prostate cancer
US6894146B1 (en) 1997-02-25 2005-05-17 Corixa Corporation Compositions and methods for the therapy and diagnosis of prostate cancer
US20030185830A1 (en) 1997-02-25 2003-10-02 Corixa Corporation Compositions and methods for the therapy and diagnosis of prostate cancer
US6329505B1 (en) 1997-02-25 2001-12-11 Corixa Corporation Compositions and methods for therapy and diagnosis of prostate cancer
US7033827B2 (en) 1997-02-25 2006-04-25 Corixa Corporation Prostate-specific polynucleotide compositions
DE69840669D1 (de) 1997-04-10 2009-04-30 Stichting Katholieke Univ Pca3, pca3-gene und verfahren zu ihrer verwendung
US6861215B1 (en) 1998-05-21 2005-03-01 Diadexus, Inc. Method of diagnosing, monitoring, and staging prostate cancer
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US7494646B2 (en) 2001-09-06 2009-02-24 Agensys, Inc. Antibodies and molecules derived therefrom that bind to STEAP-1 proteins
EP1474516B1 (fr) 2002-01-25 2013-03-27 The Regents of The University of California Procedes de modulation de la perception du froid
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JP4969444B2 (ja) * 2005-06-14 2012-07-04 ディナベック株式会社 抗体の作製方法
BRPI0717638A2 (pt) 2006-10-27 2013-11-12 Genentech Inc Anticorpors e imunoconjugados e usos para os mesmos
BR112014029417B1 (pt) * 2012-05-25 2023-03-07 Cellectis Método ex vivo para a preparação de células t para imunoterapia
CN104357451B (zh) * 2014-12-02 2016-09-21 广州市番禺区中心医院 针对dd3基因的小干扰rna及其表达载体构建与应用
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EP4178976A1 (fr) * 2020-07-13 2023-05-17 The United States of America, as represented by the Secretary, Department of Health and Human Services Récepteurs de lymphocytes t à restriction hla de classe ii dirigés contre ras ayant une mutation g12d
JP2024501482A (ja) * 2020-12-14 2024-01-12 ビオンテック ユーエス インコーポレイテッド がん免疫療法のための組織特異的抗原
CN114250238B (zh) * 2021-11-26 2023-08-25 北京航空航天大学 基因编码的神经元发育调控多肽及其应用

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Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9617346B2 (en) 2004-04-22 2017-04-11 Agensys, Inc. Antibodies and molecules derived therefrom that bind to STEAP-1 proteins
US10597463B2 (en) 2004-04-22 2020-03-24 Agensys, Inc. Antibodies and molecules derived therefrom that bind to STEAP-1 proteins
US11401347B2 (en) 2004-04-22 2022-08-02 Agensys, Inc. Antibodies and molecules derived therefrom that bind to STEAP-1 proteins
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KR20030016217A (ko) 2003-02-26
HUP0203968A3 (en) 2004-09-28
IL150732A0 (en) 2003-02-12
RU2002121771A (ru) 2004-03-10
MXPA02006934A (es) 2003-01-28
WO2001051633A9 (fr) 2002-10-31
BR0107643A (pt) 2003-06-10
CZ20022756A3 (cs) 2003-02-12
CN1436234A (zh) 2003-08-13
HUP0203968A2 (hu) 2003-03-28
NO20023402D0 (no) 2002-07-15
JP2003528591A (ja) 2003-09-30
CA2397741A1 (fr) 2001-07-19
WO2001051633A2 (fr) 2001-07-19
EP1261708A2 (fr) 2002-12-04
ZA200206400B (en) 2004-01-21
PL356908A1 (en) 2004-07-12
AU3447401A (en) 2001-07-24
NO20023402L (no) 2002-08-29

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