WO2002004656A3 - Biosonden und deren verwendung - Google Patents

Biosonden und deren verwendung Download PDF

Info

Publication number
WO2002004656A3
WO2002004656A3 PCT/EP2001/007259 EP0107259W WO0204656A3 WO 2002004656 A3 WO2002004656 A3 WO 2002004656A3 EP 0107259 W EP0107259 W EP 0107259W WO 0204656 A3 WO0204656 A3 WO 0204656A3
Authority
WO
WIPO (PCT)
Prior art keywords
probes
bio
biological material
dielectrophoresis
electrophoresis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/EP2001/007259
Other languages
English (en)
French (fr)
Other versions
WO2002004656A2 (de
Inventor
Peter Wagner
Thomas Polakowski
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Phylos Inc
Original Assignee
Phylos Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Phylos Inc filed Critical Phylos Inc
Priority to CA002415253A priority Critical patent/CA2415253A1/en
Priority to JP2002509509A priority patent/JP2004502462A/ja
Priority to AU2001277519A priority patent/AU2001277519A1/en
Priority to EP01955323A priority patent/EP1305626A2/de
Publication of WO2002004656A2 publication Critical patent/WO2002004656A2/de
Publication of WO2002004656A3 publication Critical patent/WO2002004656A3/de
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416—Systems
    • G01N27/447—Systems using electrophoresis
    • G01N27/44704—Details; Accessories
    • G01N27/44717—Arrangements for investigating the separated zones, e.g. localising zones
    • G01N27/44721—Arrangements for investigating the separated zones, e.g. localising zones by optical means
    • G01N27/44726—Arrangements for investigating the separated zones, e.g. localising zones by optical means using specific dyes, markers or binding molecules
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C5/00—Separating dispersed particles from liquids by electrostatic effect
    • B03C5/005—Dielectrophoresis, i.e. dielectric particles migrating towards the region of highest field strength

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Physics & Mathematics (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Electrochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

Die Erfindung betrifft den Einsatz von Biosonden, die spezifisch an biologisches Material binden und dadurch die Detektion und/oder Trennung des so markierten Materials aus einer Umgebung ähnlichen biologischen Materials mittels Elektrophorese oder Dielektrophorese ermöglichen. Die Biosonden zeichnen sich dadurch aus, daß sie die elektrischen und/oder dielektrischen Eigenschaften des biologischen Materials verändern.
PCT/EP2001/007259 2000-07-07 2001-06-26 Biosonden und deren verwendung Ceased WO2002004656A2 (de)

Priority Applications (4)

Application Number Priority Date Filing Date Title
CA002415253A CA2415253A1 (en) 2000-07-07 2001-06-26 Bio-probes and use thereof
JP2002509509A JP2004502462A (ja) 2000-07-07 2001-06-26 バイオプローブ及びその使用
AU2001277519A AU2001277519A1 (en) 2000-07-07 2001-06-26 Bio-probes and use thereof
EP01955323A EP1305626A2 (de) 2000-07-07 2001-06-26 Biosonden und deren verwendung

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10033194A DE10033194C2 (de) 2000-07-07 2000-07-07 Biosonden und deren Verwendung
DE10033194.7 2000-07-07

Publications (2)

Publication Number Publication Date
WO2002004656A2 WO2002004656A2 (de) 2002-01-17
WO2002004656A3 true WO2002004656A3 (de) 2002-09-19

Family

ID=7648218

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2001/007259 Ceased WO2002004656A2 (de) 2000-07-07 2001-06-26 Biosonden und deren verwendung

Country Status (6)

Country Link
EP (1) EP1305626A2 (de)
JP (1) JP2004502462A (de)
AU (1) AU2001277519A1 (de)
CA (1) CA2415253A1 (de)
DE (1) DE10033194C2 (de)
WO (1) WO2002004656A2 (de)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7067046B2 (en) 2000-08-04 2006-06-27 Essen Instruments, Inc. System for rapid chemical activation in high-throughput electrophysiological measurements
US7201836B2 (en) 1997-12-17 2007-04-10 Molecular Devices Corporation Multiaperture sample positioning and analysis system
US7244349B2 (en) 1997-12-17 2007-07-17 Molecular Devices Corporation Multiaperture sample positioning and analysis system
US7270730B2 (en) 2000-08-04 2007-09-18 Essen Instruments, Inc. High-throughput electrophysiological measurement system

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998031700A1 (en) * 1997-01-21 1998-07-23 The General Hospital Corporation Selection of proteins using rna-protein fusions
WO1999051773A1 (en) * 1998-04-03 1999-10-14 Phylos, Inc. Addressable protein arrays

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998031700A1 (en) * 1997-01-21 1998-07-23 The General Hospital Corporation Selection of proteins using rna-protein fusions
WO1999051773A1 (en) * 1998-04-03 1999-10-14 Phylos, Inc. Addressable protein arrays

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
FIEDLER S ET AL: "DIELECTROPHORETIC SORTING OF PARTICLES AND CELLS IN A MICROSYSTEM", ANALYTICAL CHEMISTRY, AMERICAN CHEMICAL SOCIETY. COLUMBUS, US, vol. 70, no. 9, 1 May 1998 (1998-05-01), pages 1909 - 1915, XP000755524, ISSN: 0003-2700 *
ROBERTS R W ET AL: "RNA-PEPTIDE FUSIONS FOR THE IN VITRO SELECTION OF PEPTIDES AND PROTEINS", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, NATIONAL ACADEMY OF SCIENCE. WASHINGTON, US, vol. 94, November 1997 (1997-11-01), pages 12297 - 12302, XP000904377, ISSN: 0027-8424 *

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7201836B2 (en) 1997-12-17 2007-04-10 Molecular Devices Corporation Multiaperture sample positioning and analysis system
US7244349B2 (en) 1997-12-17 2007-07-17 Molecular Devices Corporation Multiaperture sample positioning and analysis system
US7387715B2 (en) 1997-12-17 2008-06-17 Molecular Devices Corporation Sample positioning and analysis system
US7067046B2 (en) 2000-08-04 2006-06-27 Essen Instruments, Inc. System for rapid chemical activation in high-throughput electrophysiological measurements
US7270730B2 (en) 2000-08-04 2007-09-18 Essen Instruments, Inc. High-throughput electrophysiological measurement system

Also Published As

Publication number Publication date
WO2002004656A2 (de) 2002-01-17
DE10033194C2 (de) 2002-07-18
AU2001277519A1 (en) 2002-01-21
DE10033194A1 (de) 2002-01-24
JP2004502462A (ja) 2004-01-29
CA2415253A1 (en) 2002-01-17
EP1305626A2 (de) 2003-05-02

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