WO2003020258A1 - Anti-influenza drugs - Google Patents

Anti-influenza drugs Download PDF

Info

Publication number: WO2003020258A1
Authority: WO; WIPO (PCT)
Prior art keywords: airway; influenza; drugs; influenza virus; secretion
Prior art date: 2001-09-04
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Ceased

Application number

PCT/JP2002/008940

Other languages

English (en)

French (fr)

Inventor

Hiroshi Kido

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Boehringer Ingelheim International GmbH

Techno Network Shikoku Co Ltd

Original Assignee

Boehringer Ingelheim International GmbH

Techno Network Shikoku Co Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-09-04

Filing date

2002-09-03

Publication date

2003-03-13

2002-09-03 Priority to MXPA04002066A priority Critical patent/MXPA04002066A/es

2002-09-03 Priority to HU0402299A priority patent/HUP0402299A3/hu

2002-09-03 Priority to BR0212232-4A priority patent/BR0212232A/pt

2002-09-03 Priority to EP02762982A priority patent/EP1437134A4/en

2002-09-03 Priority to KR10-2004-7003276A priority patent/KR20040045429A/ko

2002-09-03 Priority to CA002459492A priority patent/CA2459492A1/en

2002-09-03 Priority to HK05101866.4A priority patent/HK1069526B/xx

2002-09-03 Priority to IL16053902A priority patent/IL160539A0/xx

2002-09-03 Priority to NZ532019A priority patent/NZ532019A/en

2002-09-03 Application filed by Boehringer Ingelheim International GmbH, Techno Network Shikoku Co Ltd filed Critical Boehringer Ingelheim International GmbH

2003-03-13 Publication of WO2003020258A1 publication Critical patent/WO2003020258A1/ja

2004-02-27 Priority to US10/790,448 priority patent/US20040242700A1/en

2004-03-04 Anticipated expiration legal-status Critical

Status Ceased legal-status Critical Current

Links

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Virology (AREA)
Emergency Medicine (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Pulmonology (AREA)
Communicable Diseases (AREA)
Molecular Biology (AREA)
Oncology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)

PCT/JP2002/008940 2001-09-04 2002-09-03 Anti-influenza drugs Ceased WO2003020258A1 (en)

Priority Applications (10)

Application Number	Priority Date	Filing Date	Title
IL16053902A IL160539A0 (en)	2001-09-04	2002-09-03	Anti-influenzal agents
HU0402299A HUP0402299A3 (en)	2001-09-04	2002-09-03	Anti-influenza drugs containing ambroxol and bromhexine and process for its preparation
BR0212232-4A BR0212232A (pt)	2001-09-04	2002-09-03	Agente antiinfluenza
EP02762982A EP1437134A4 (en)	2001-09-04	2002-09-03	FLU RESOURCES
KR10-2004-7003276A KR20040045429A (ko)	2001-09-04	2002-09-03	항인플루엔자 약제
MXPA04002066A MXPA04002066A (es)	2001-09-04	2002-09-03	Farmacos contra influenza.
HK05101866.4A HK1069526B (en)	2001-09-04	2002-09-03	Anti-influenza drugs
CA002459492A CA2459492A1 (en)	2001-09-04	2002-09-03	Anti-influenzal agent
NZ532019A NZ532019A (en)	2001-09-04	2002-09-03	Anti-influenza drugs
US10/790,448 US20040242700A1 (en)	2001-09-04	2004-02-27	Anti-influenzal agent

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
JP2001-267236		2001-09-04
JP2001267236		2001-09-04

Related Child Applications (1)

Application Number	Title	Priority Date	Filing Date
US10/790,448 Continuation US20040242700A1 (en)	2001-09-04	2004-02-27	Anti-influenzal agent

Publications (1)

Publication Number	Publication Date
WO2003020258A1 true WO2003020258A1 (en)	2003-03-13

Family

ID=19093396

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PCT/JP2002/008940 Ceased WO2003020258A1 (en)	2001-09-04	2002-09-03	Anti-influenza drugs

Country Status (11)

Country	Link
US (1)	US20040242700A1 (ja)
EP (1)	EP1437134A4 (ja)
KR (1)	KR20040045429A (ja)
CN (1)	CN1267091C (ja)
BR (1)	BR0212232A (ja)
CA (1)	CA2459492A1 (ja)
HU (1)	HUP0402299A3 (ja)
IL (1)	IL160539A0 (ja)
MX (1)	MXPA04002066A (ja)
NZ (1)	NZ532019A (ja)
WO (1)	WO2003020258A1 (ja)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US20030166732A1 (en) *	2002-02-27	2003-09-04	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Ambroxol for the treatment of painful conditions in the mouth and pharyngeal cavity
ITMI20032463A1 (it) *	2003-12-16	2005-06-17	Advance Holdings Ltd	Soluzione acquosa concentrata a base di ambroxolo
JP2009506002A (ja) *	2005-08-25	2009-02-12	ベーリンガーインゲルハイムインターナショナルゲゼルシャフトミットベシュレンクテルハフツング	ライノウィルスの感染症治療の為のアンブロキソールの使用
EP2138172A4 (en) *	2007-03-19	2010-04-28	Yuuzou Tsuchida	ANTIVIRAL ACTIVE SUBSTANCE
JP5337405B2 (ja)	2007-09-17	2013-11-06	ザ・ホスピタル・フォー・シック・チルドレン	ゴーシェ病の治療方法
US11583543B2 (en)	2017-07-16	2023-02-21	Neuere, Llc	Ambroxol to improve and/or extend healthspan, lifespan and/or mental acuity
EP3743039A1 (en)	2018-01-26	2020-12-02	Neuere, LLC	Use of ambroxol to improve skin barrier function
JP7771045B2 (ja)	2019-07-09	2025-11-17	ジェネトン	糖原病（ｇｓｄ）の処置
WO2021255129A1 (en) *	2020-06-16	2021-12-23	Spedding Research Solutions, Sas	Novel use of a modulator of glucosylceramide degradation for viral infections
JP2024540241A (ja)	2021-10-28	2024-10-31	ザイウィー，エルエルシー	治療上の使用のためのアンブロキソールの修飾形態
EP4705274A1 (en)	2023-05-02	2026-03-11	Zywie LLC	Modified forms of ambroxol for therapeutic use

Citations (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1994008551A2 (en) *	1992-10-09	1994-04-28	The Procter & Gamble Company	Pharmaceutical compositions and methods for treating cold symptoms
WO1994014476A1 (en) *	1992-12-21	1994-07-07	The Procter & Gamble Company	Use of s(+) antipodes of analgesic agents for the manufacture of a composition to treat respiratory disorders
JPH06287144A (ja) *	1993-02-03	1994-10-11	Takeda Chem Ind Ltd	かぜ薬製剤
WO1995007103A1 (en) *	1993-09-07	1995-03-16	The Procter & Gamble Company	Compositions containing an amino acid salt of propionic acid non-steroidal anti-inflammatory agent and at least one of a decongestant, an expectorant, an antihistamine and an antitussive

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3610997A1 (de) *	1986-04-02	1987-10-15	Krewel Werke Gmbh	Ambroxol-nasenspray
JPH11510168A (ja) *	1995-07-28	1999-09-07	ザ、プロクター、エンド、ギャンブル、カンパニー	呼吸障害を処理するための鎮痛剤及び抗ヒスタミン剤を含有する組成物及び方法
US5648358A (en) *	1996-03-05	1997-07-15	Mitra; Sekhar	Compositions and methods for treating respiratory disorders
US5885594A (en) *	1997-03-27	1999-03-23	The Procter & Gamble Company	Oral compositions having enhanced mouth-feel

2002
- 2002-09-03 IL IL16053902A patent/IL160539A0/xx unknown
- 2002-09-03 CN CNB028170601A patent/CN1267091C/zh not_active Expired - Fee Related
- 2002-09-03 KR KR10-2004-7003276A patent/KR20040045429A/ko not_active Ceased
- 2002-09-03 WO PCT/JP2002/008940 patent/WO2003020258A1/ja not_active Ceased
- 2002-09-03 CA CA002459492A patent/CA2459492A1/en not_active Abandoned
- 2002-09-03 MX MXPA04002066A patent/MXPA04002066A/es not_active Application Discontinuation
- 2002-09-03 BR BR0212232-4A patent/BR0212232A/pt not_active IP Right Cessation
- 2002-09-03 EP EP02762982A patent/EP1437134A4/en not_active Withdrawn
- 2002-09-03 HU HU0402299A patent/HUP0402299A3/hu unknown
- 2002-09-03 NZ NZ532019A patent/NZ532019A/en unknown
2004
- 2004-02-27 US US10/790,448 patent/US20040242700A1/en not_active Abandoned

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1994008551A2 (en) *	1992-10-09	1994-04-28	The Procter & Gamble Company	Pharmaceutical compositions and methods for treating cold symptoms
WO1994014476A1 (en) *	1992-12-21	1994-07-07	The Procter & Gamble Company	Use of s(+) antipodes of analgesic agents for the manufacture of a composition to treat respiratory disorders
JPH06287144A (ja) *	1993-02-03	1994-10-11	Takeda Chem Ind Ltd	かぜ薬製剤
WO1995007103A1 (en) *	1993-09-07	1995-03-16	The Procter & Gamble Company	Compositions containing an amino acid salt of propionic acid non-steroidal anti-inflammatory agent and at least one of a decongestant, an expectorant, an antihistamine and an antitussive

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
DATABASE CAPLUS [online] NISHIKAWA M. ET AL.: "Ambroxol suppresses influenza virus multiplication in the airway by increasing antiviral factor levels", XP002961052, accession no. STN Database accession no. 2002:542180 *
DATABASE CAPLUS [online] YANG B. ET AL.: "Ambroxol suppresses influenza-virus proliferation in the mouse airway by increasing antiviral factor levels", XP002961053, accession no. STN Database accession no. 2002:444958 *
EUROPEAN RESPIRATORY JOURNAL, vol. 19, no. 5, 2002, pages 952 - 958 *
See also references of EP1437134A4 *
TOKUSHIMA IGAKKAI, vol. 58, no. 3, 2002, pages 162 - 167 *

Also Published As

Publication number	Publication date
MXPA04002066A (es)	2005-02-17
HUP0402299A2 (hu)	2005-02-28
NZ532019A (en)	2007-04-27
KR20040045429A (ko)	2004-06-01
HK1069526A1 (en)	2005-05-27
CN1549708A (zh)	2004-11-24
HUP0402299A3 (en)	2008-04-28
CN1267091C (zh)	2006-08-02
CA2459492A1 (en)	2003-03-13
BR0212232A (pt)	2004-10-05
IL160539A0 (en)	2004-07-25
EP1437134A4 (en)	2009-03-11
EP1437134A1 (en)	2004-07-14
US20040242700A1 (en)	2004-12-02

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