WO2003020258A1 - Anti-influenza drugs - Google Patents

Anti-influenza drugs Download PDF

Info

Publication number: WO2003020258A1
Authority: WO; WIPO (PCT)
Prior art keywords: airway; influenza; drugs; influenza virus; secretion
Prior art date: 2001-09-04
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Ceased

Application number

PCT/JP2002/008940

Other languages

English (en)

French (fr)

Inventor

Hiroshi Kido

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Boehringer Ingelheim International GmbH

Techno Network Shikoku Co Ltd

Original Assignee

Boehringer Ingelheim International GmbH

Techno Network Shikoku Co Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-09-04

Filing date

2002-09-03

Publication date

2003-03-13

2002-09-03 Priority to HK05101866.4A priority Critical patent/HK1069526B/xx

2002-09-03 Priority to KR10-2004-7003276A priority patent/KR20040045429A/ko

2002-09-03 Priority to MXPA04002066A priority patent/MXPA04002066A/es

2002-09-03 Priority to NZ532019A priority patent/NZ532019A/en

2002-09-03 Priority to EP02762982A priority patent/EP1437134A4/en

2002-09-03 Priority to IL16053902A priority patent/IL160539A0/xx

2002-09-03 Priority to BR0212232-4A priority patent/BR0212232A/pt

2002-09-03 Priority to HU0402299A priority patent/HUP0402299A3/hu

2002-09-03 Priority to CA002459492A priority patent/CA2459492A1/en

2002-09-03 Application filed by Boehringer Ingelheim International GmbH, Techno Network Shikoku Co Ltd filed Critical Boehringer Ingelheim International GmbH

2003-03-13 Publication of WO2003020258A1 publication Critical patent/WO2003020258A1/ja

2004-02-27 Priority to US10/790,448 priority patent/US20040242700A1/en

2004-03-04 Anticipated expiration legal-status Critical

Status Ceased legal-status Critical Current

Links

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Public Health (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Virology (AREA)
Emergency Medicine (AREA)
Epidemiology (AREA)
Chemical Kinetics & Catalysis (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Molecular Biology (AREA)
Pulmonology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)

PCT/JP2002/008940 2001-09-04 2002-09-03 Anti-influenza drugs Ceased WO2003020258A1 (en)

Priority Applications (10)

Application Number	Priority Date	Filing Date	Title
HU0402299A HUP0402299A3 (en)	2001-09-04	2002-09-03	Anti-influenza drugs containing ambroxol and bromhexine and process for its preparation
KR10-2004-7003276A KR20040045429A (ko)	2001-09-04	2002-09-03	항인플루엔자 약제
MXPA04002066A MXPA04002066A (es)	2001-09-04	2002-09-03	Farmacos contra influenza.
NZ532019A NZ532019A (en)	2001-09-04	2002-09-03	Anti-influenza drugs
EP02762982A EP1437134A4 (en)	2001-09-04	2002-09-03	FLU RESOURCES
HK05101866.4A HK1069526B (en)	2001-09-04	2002-09-03	Anti-influenza drugs
BR0212232-4A BR0212232A (pt)	2001-09-04	2002-09-03	Agente antiinfluenza
IL16053902A IL160539A0 (en)	2001-09-04	2002-09-03	Anti-influenzal agents
CA002459492A CA2459492A1 (en)	2001-09-04	2002-09-03	Anti-influenzal agent
US10/790,448 US20040242700A1 (en)	2001-09-04	2004-02-27	Anti-influenzal agent

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
JP2001-267236		2001-09-04
JP2001267236		2001-09-04

Related Child Applications (1)

Application Number	Title	Priority Date	Filing Date
US10/790,448 Continuation US20040242700A1 (en)	2001-09-04	2004-02-27	Anti-influenzal agent

Publications (1)

Publication Number	Publication Date
WO2003020258A1 true WO2003020258A1 (en)	2003-03-13

Family

ID=19093396

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PCT/JP2002/008940 Ceased WO2003020258A1 (en)	2001-09-04	2002-09-03	Anti-influenza drugs

Country Status (11)

Country	Link
US (1)	US20040242700A1 (ja)
EP (1)	EP1437134A4 (ja)
KR (1)	KR20040045429A (ja)
CN (1)	CN1267091C (ja)
BR (1)	BR0212232A (ja)
CA (1)	CA2459492A1 (ja)
HU (1)	HUP0402299A3 (ja)
IL (1)	IL160539A0 (ja)
MX (1)	MXPA04002066A (ja)
NZ (1)	NZ532019A (ja)
WO (1)	WO2003020258A1 (ja)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US20030166732A1 (en) *	2002-02-27	2003-09-04	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Ambroxol for the treatment of painful conditions in the mouth and pharyngeal cavity
ITMI20032463A1 (it) *	2003-12-16	2005-06-17	Advance Holdings Ltd	Soluzione acquosa concentrata a base di ambroxolo
BRPI0614887A2 (pt) *	2005-08-25	2011-04-19	Boehringer Ingelheim Int	uso de ambroxol para o tratamento de infecções por rinovìrus
EP2138172A4 (en) *	2007-03-19	2010-04-28	Yuuzou Tsuchida	ANTIVIRAL ACTIVE SUBSTANCE
JP5337405B2 (ja)	2007-09-17	2013-11-06	ザ・ホスピタル・フォー・シック・チルドレン	ゴーシェ病の治療方法
EP3654960A1 (en)	2017-07-16	2020-05-27	Neuere, LLC	Ambroxol to improve and/or extend healthspan, lifespan and/or mental acuity
JP7369716B2 (ja)	2018-01-26	2023-10-26	ノイレ，エルエルシー	皮膚バリア機能を改善するためのアンブロキソールの使用
EP3996696A1 (en)	2019-07-09	2022-05-18	Genethon	Treatment of glycogen storage disease (gsd)
WO2021255129A1 (en) *	2020-06-16	2021-12-23	Spedding Research Solutions, Sas	Novel use of a modulator of glucosylceramide degradation for viral infections
CN118660866A (zh)	2021-10-28	2024-09-17	启威公司	治疗用改良型氨溴索
CN121127451A (zh)	2023-05-02	2025-12-12	启威公司	一种用于医疗用途的改良型氨溴索

Citations (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1994008551A2 (en) *	1992-10-09	1994-04-28	The Procter & Gamble Company	Pharmaceutical compositions and methods for treating cold symptoms
WO1994014476A1 (en) *	1992-12-21	1994-07-07	The Procter & Gamble Company	Use of s(+) antipodes of analgesic agents for the manufacture of a composition to treat respiratory disorders
JPH06287144A (ja) *	1993-02-03	1994-10-11	Takeda Chem Ind Ltd	かぜ薬製剤
WO1995007103A1 (en) *	1993-09-07	1995-03-16	The Procter & Gamble Company	Compositions containing an amino acid salt of propionic acid non-steroidal anti-inflammatory agent and at least one of a decongestant, an expectorant, an antihistamine and an antitussive

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3610997A1 (de) *	1986-04-02	1987-10-15	Krewel Werke Gmbh	Ambroxol-nasenspray
JPH11510168A (ja) *	1995-07-28	1999-09-07	ザ、プロクター、エンド、ギャンブル、カンパニー	呼吸障害を処理するための鎮痛剤及び抗ヒスタミン剤を含有する組成物及び方法
US5648358A (en) *	1996-03-05	1997-07-15	Mitra; Sekhar	Compositions and methods for treating respiratory disorders
US5885594A (en) *	1997-03-27	1999-03-23	The Procter & Gamble Company	Oral compositions having enhanced mouth-feel

2002
- 2002-09-03 MX MXPA04002066A patent/MXPA04002066A/es not_active Application Discontinuation
- 2002-09-03 WO PCT/JP2002/008940 patent/WO2003020258A1/ja not_active Ceased
- 2002-09-03 CN CNB028170601A patent/CN1267091C/zh not_active Expired - Fee Related
- 2002-09-03 NZ NZ532019A patent/NZ532019A/en unknown
- 2002-09-03 BR BR0212232-4A patent/BR0212232A/pt not_active IP Right Cessation
- 2002-09-03 IL IL16053902A patent/IL160539A0/xx unknown
- 2002-09-03 CA CA002459492A patent/CA2459492A1/en not_active Abandoned
- 2002-09-03 HU HU0402299A patent/HUP0402299A3/hu unknown
- 2002-09-03 EP EP02762982A patent/EP1437134A4/en not_active Withdrawn
- 2002-09-03 KR KR10-2004-7003276A patent/KR20040045429A/ko not_active Ceased
2004
- 2004-02-27 US US10/790,448 patent/US20040242700A1/en not_active Abandoned

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1994008551A2 (en) *	1992-10-09	1994-04-28	The Procter & Gamble Company	Pharmaceutical compositions and methods for treating cold symptoms
WO1994014476A1 (en) *	1992-12-21	1994-07-07	The Procter & Gamble Company	Use of s(+) antipodes of analgesic agents for the manufacture of a composition to treat respiratory disorders
JPH06287144A (ja) *	1993-02-03	1994-10-11	Takeda Chem Ind Ltd	かぜ薬製剤
WO1995007103A1 (en) *	1993-09-07	1995-03-16	The Procter & Gamble Company	Compositions containing an amino acid salt of propionic acid non-steroidal anti-inflammatory agent and at least one of a decongestant, an expectorant, an antihistamine and an antitussive

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
DATABASE CAPLUS [online] NISHIKAWA M. ET AL.: "Ambroxol suppresses influenza virus multiplication in the airway by increasing antiviral factor levels", XP002961052, accession no. STN Database accession no. 2002:542180 *
DATABASE CAPLUS [online] YANG B. ET AL.: "Ambroxol suppresses influenza-virus proliferation in the mouse airway by increasing antiviral factor levels", XP002961053, accession no. STN Database accession no. 2002:444958 *
EUROPEAN RESPIRATORY JOURNAL, vol. 19, no. 5, 2002, pages 952 - 958 *
See also references of EP1437134A4 *
TOKUSHIMA IGAKKAI, vol. 58, no. 3, 2002, pages 162 - 167 *

Also Published As

Publication number	Publication date
HUP0402299A3 (en)	2008-04-28
HUP0402299A2 (hu)	2005-02-28
HK1069526A1 (en)	2005-05-27
EP1437134A4 (en)	2009-03-11
CN1267091C (zh)	2006-08-02
MXPA04002066A (es)	2005-02-17
BR0212232A (pt)	2004-10-05
NZ532019A (en)	2007-04-27
CN1549708A (zh)	2004-11-24
EP1437134A1 (en)	2004-07-14
KR20040045429A (ko)	2004-06-01
CA2459492A1 (en)	2003-03-13
IL160539A0 (en)	2004-07-25
US20040242700A1 (en)	2004-12-02

Similar Documents

Publication	Publication Date	Title
WO2003020258A1 (en)	2003-03-13	Anti-influenza drugs
ATE276244T1 (de)	2004-10-15	Replikationsinhibitoren des respiratorischen synzytialvirus
AU2002346973A1 (en)	2003-07-03	Oral Dosage Form for Propiverine or its Pharmaceutically Acceptable Salts with an Extended Release of the Active Ingredient
SI1435915T1 (sl)	2008-12-31	Oralne dozirne oblike za propiverin ali njegove farmacevtsko sprejemljive soli s podaljšanim sproščanjem učinkovine
NO20016369D0 (no)	2001-12-27	Respiratorisk syncytialvirus-replikasjonsinhibitorer
BR0112756A (pt)	2003-06-24	Composto, composição farmacêutica, métodos para o tratamento de doenças mediadas por prostaglandina, de congestão nasal, asma alérgica, e rinite alérgica, e, uso de um composto
NO20041277L (no)	2004-03-26	Farmasoytiske preparater for behandling av astma.
BR0307050A (pt)	2004-10-26	Composto, composição farmacêutica, métodos para o tratamento de doenças mediadas por prostaglandina d2, para o tratamento de congestão nasal, para o tratamento de asma alérgica, e para o tratamento de rinite alérgica, sal farmaceuticamente aceitável, e, uso de um composto ou sal
ATE392863T1 (de)	2008-05-15	Streifen zur abgabe eines mundpflegewirkstoffes
NO20016370L (no)	2001-12-27	Respiratorisk syncytialvirus-replikasjonsinhibitorer
EA200400481A1 (ru)	2004-10-28	Применение флибансерина для лечения половых расстройств
DK1572153T3 (da)	2012-03-05	Fremstilling af sterile vandige suspensioner, som omfatter mikroniserede krystallinske virksomme stoffer til inhalering
AR030829A1 (es)	2003-09-03	Una formulacion de vacuna, procedimiento para la produccion de la misma, uso de dicha preparacion y un estuche para su administracion via intranasal
MXPA03009391A (es)	2004-01-29	METODO PARA FABRICAR UNA COMPOSICIoN FARMACEUTICA DE DOSIS BAJA.
DE60336225D1 (de)	2011-04-14	Neue pharmazeutische zusammenstezungen, flibanserin polymorph a enthaltend
DK1957037T3 (da)	2010-07-19	Farmaceutisk præparat til nasal anvendelse af fentanyl
ATE240717T1 (de)	2003-06-15	Wässrige formulierung zur nasalen verabreichung
BRPI0411623A (pt)	2006-08-08	forma de dosagem farmacêutica ou dietética, esporopolenina, método para a formação de uma esporopolenina funcionalizada com amina primária ou um outro revestimento de exina, método para a formação de uma esporopolenina funcionalizada com poliamino ou um outro revestimento de exina de um esporo, método para a obtenção de uma esporopolenina funcionalizada com aminoácido ou um outro revestimento de exina de um esporo, esporopolenina funcionalizada ou um outro revestimento de exina de um esporo, forma de dosagem dietética ou flavorizante, método de preenchimento de revestimentos de exina de esporos, uso da forma de dosagem e método de aplicação oral de um ingrediente ativo
EA200600603A1 (ru)	2006-08-25	Оральная система доставки лекарственного препарата
TW200501935A (en)	2005-01-16	Use of resveratrol for preparation of a medicament useful for the treatment of influenza virus infections
WO2005051350A3 (en)	2005-08-18	Water dispersible tablet
WO2005065639A3 (en)	2005-09-01	Novel pharmaceutical compositions
ECSP014082A (es)	2002-04-23	Combinacion de secretagogos de hormona del crecimiento y antidepresivos
WO2008020314A3 (en)	2009-04-23	Statin stabilizing dosage formulations
WO2006071896A3 (en)	2007-04-26	Epitope-based sars vaccine

Legal Events

Date	Code	Title	Description
2003-03-13	AK	Designated states	Kind code of ref document: A1 Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE ES FI GB GD GE GH GM HR HU ID IL IN IS KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NO NZ OM PH PL PT RO RU SD SE SG SI SK SL TJ TM TN TR TT TZ UA UG US UZ VC VN YU ZA ZM ZW Kind code of ref document: A1 Designated state(s): AE AG AL AM AT AU AZ BA BB BG BY BZ CA CH CN CO CR CU CZ DE DM DZ EC EE ES FI GB GD GE GH HR HU ID IL IN IS KE KG KP KR KZ LK LR LS LT LU LV MA MD MG MK MW MX MZ NO NZ OM PH PL PT RO SD SE SG SI SK SL TJ TM TN TR TT UA UG US UZ VC VN YU ZA ZM
2003-03-13	AL	Designated countries for regional patents	Kind code of ref document: A1 Designated state(s): GH GM KE LS MW MZ SD SL SZ UG ZM ZW AM AZ BY KG KZ RU TJ TM AT BE BG CH CY CZ DK EE ES FI FR GB GR IE IT LU MC PT SE SK TR BF BJ CF CG CI GA GN GQ GW ML MR NE SN TD TG Kind code of ref document: A1 Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZM ZW AM AZ BY KG KZ MD RU TJ TM AT BE BG CH CY CZ DE DK EE ES FI FR GB GR IE IT LU MC NL PT SE SK TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG
2003-05-07	121	Ep: the epo has been informed by wipo that ep was designated in this application
2004-02-24	WWE	Wipo information: entry into national phase	Ref document number: 160539 Country of ref document: IL
2004-02-27	WWE	Wipo information: entry into national phase	Ref document number: 10790448 Country of ref document: US
2004-03-01	WWE	Wipo information: entry into national phase	Ref document number: 20028170601 Country of ref document: CN
2004-03-03	WWE	Wipo information: entry into national phase	Ref document number: PA/a/2004/002066 Country of ref document: MX Ref document number: 2459492 Country of ref document: CA
2004-03-04	WWE	Wipo information: entry into national phase	Ref document number: 1020047003276 Country of ref document: KR
2004-03-23	WWE	Wipo information: entry into national phase	Ref document number: 2002328415 Country of ref document: AU
2004-03-30	WWE	Wipo information: entry into national phase	Ref document number: 532019 Country of ref document: NZ
2004-03-31	WWE	Wipo information: entry into national phase	Ref document number: 2002762982 Country of ref document: EP
2004-04-15	DFPE	Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
2004-07-14	WWP	Wipo information: published in national office	Ref document number: 2002762982 Country of ref document: EP