WO2003106661A3 - Glutaminfreies medium - Google Patents

Glutaminfreies medium Download PDF

Info

Publication number
WO2003106661A3
WO2003106661A3 PCT/EP2003/004875 EP0304875W WO03106661A3 WO 2003106661 A3 WO2003106661 A3 WO 2003106661A3 EP 0304875 W EP0304875 W EP 0304875W WO 03106661 A3 WO03106661 A3 WO 03106661A3
Authority
WO
WIPO (PCT)
Prior art keywords
cell culture
glutamine
free environment
culture medium
lactate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/EP2003/004875
Other languages
English (en)
French (fr)
Other versions
WO2003106661A2 (de
Inventor
Ruediger Alt
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to EP03759889A priority Critical patent/EP1516045B1/de
Priority to AU2003242533A priority patent/AU2003242533A1/en
Priority to DE50311218T priority patent/DE50311218D1/de
Publication of WO2003106661A2 publication Critical patent/WO2003106661A2/de
Publication of WO2003106661A3 publication Critical patent/WO2003106661A3/de
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0018—Culture media for cell or tissue culture
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/30—Organic components
    • C12N2500/32—Amino acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/30—Organic components
    • C12N2500/34—Sugars

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)

Abstract

Zellkulturmedium, insbesondere für die Kultivierung von Säugerzellen, Verfahren zur Herstellung eines Zellkulturmediums, Verfahren zur Kultivierung von Zellen und die Verwendung des Zellkulturmediums zur Verminderung der Bildung von Lactat, Ammoniak und/oder Ammonium in der Zellkultur.
PCT/EP2003/004875 2002-06-13 2003-05-09 Glutaminfreies medium Ceased WO2003106661A2 (de)

Priority Applications (3)

Application Number Priority Date Filing Date Title
EP03759889A EP1516045B1 (de) 2002-06-13 2003-05-09 Verwendung von glutaminfreien medium
AU2003242533A AU2003242533A1 (en) 2002-06-13 2003-05-09 Glutamine-free medium
DE50311218T DE50311218D1 (de) 2002-06-13 2003-05-09 Verwendung von glutaminfreien medium

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10226455.4 2002-06-13
DE10226455A DE10226455A1 (de) 2002-06-13 2002-06-13 Verfahren zur Kultivierung von Säugerzellen mit verminderter Hemmstoffproduktion

Publications (2)

Publication Number Publication Date
WO2003106661A2 WO2003106661A2 (de) 2003-12-24
WO2003106661A3 true WO2003106661A3 (de) 2004-02-19

Family

ID=29594508

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2003/004875 Ceased WO2003106661A2 (de) 2002-06-13 2003-05-09 Glutaminfreies medium

Country Status (5)

Country Link
EP (1) EP1516045B1 (de)
AT (1) ATE423841T1 (de)
AU (1) AU2003242533A1 (de)
DE (2) DE10226455A1 (de)
WO (1) WO2003106661A2 (de)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8053236B2 (en) 2007-05-11 2011-11-08 Amgen Inc. Feed media

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102005046225B4 (de) 2005-09-28 2012-01-05 Cellca Gmbh Verbessertes Zellkulturmedium
KR20150131280A (ko) * 2013-03-15 2015-11-24 글락소스미스클라인 인털렉츄얼 프로퍼티 (넘버 2) 리미티드 세포 배양액에서 암모니아 생성을 제어하기 위한 트리카르복실산（ｔｃａ）중간체의 용도
SG11201700023WA (en) * 2014-07-16 2017-02-27 Heartseed Inc New undifferentiated stem cell removal and myocardial purification and refinement culture medium
NL2028813B1 (en) * 2021-07-22 2023-01-27 Mosa Meat B V Serum-free media for producing adipocytes for animal consumption.

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4049494A (en) * 1975-09-04 1977-09-20 The United States Of America As Represented By The Secretary Of Agriculture Vaccine production process

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4049494A (en) * 1975-09-04 1977-09-20 The United States Of America As Represented By The Secretary Of Agriculture Vaccine production process

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
DATABASE WPI Section Ch Week 199902, Derwent World Patents Index; Class B04, AN 1999-022688, XP002265010, QUEST INT: "Use of protein hydrolysates in cell culture media - as replacements for serum, glutamine and other free amino acids" *
DOWNS STEPHEN M ET AL: "Energy substrates and the completion of spontaneous meiotic maturation", ZYGOTE, vol. 8, no. 4, November 2000 (2000-11-01), pages 339 - 351, XP008025824, ISSN: 0967-1994 *
NEERMANN J ET AL: "COMPARATIVE ANALYSIS OF GLUCOSE AND GLUTAMINE METABOLISM IN TRANSFORMED MAMMALIAN CELL LINES, INSECT AND PRIMARY LIVER CELLS", JOURNAL OF CELLULAR PHYSIOLOGY, LISS, NEW YORK, NY, US, vol. 166, no. 1, 1996, pages 152 - 169, XP000929952, ISSN: 0021-9541 *
RESEARCH DISCLOSURE, vol. 415, no. 051, 10 November 1998 (1998-11-10), Emsworth, GB, pages 1 - 3, XP007123516 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8053236B2 (en) 2007-05-11 2011-11-08 Amgen Inc. Feed media
US9228168B2 (en) 2007-05-11 2016-01-05 Amgen Inc. Feed media

Also Published As

Publication number Publication date
EP1516045A2 (de) 2005-03-23
WO2003106661A2 (de) 2003-12-24
DE10226455A1 (de) 2003-12-24
EP1516045B1 (de) 2009-02-25
AU2003242533A1 (en) 2003-12-31
DE50311218D1 (de) 2009-04-09
ATE423841T1 (de) 2009-03-15

Similar Documents

Publication Publication Date Title
Kurokawa et al. Growth characteristics in fed‐batch culture of hybridoma cells with control of glucose and glutamine concentrations
BR0015374A (pt) Diferenciação hematopoiética de troncocélulas embriÈnicas humanas
WO2003089567A3 (en) Apparatus and method for a cell culture in a bioreactor at high cell concentration
GB2432846B (en) Medium and culture of embryonic stem cells
CY1110267T1 (el) Μεθοδος για την καλλιεργεια κυτταρων για την παραγωγη ουσιων
WO2003010302A1 (en) Cultured cell construct containing spheroids of cultured animal cells and utilization thereof
NZ597334A (en) Cell culture improvements
WO2004050826A3 (en) Method of dynamically culturing embryonic stem cells
EP0642326A4 (de) Nicht faserige, mit alginat beschichtete transplantate sowie herstellungs- und anwendungssvefahren dafür.
EP1748064A4 (de) Kultivierte periodontale membranzellage, verfahren zur herstellung davon sowie verfahren zur verwendung davon
AU4017501A (en) Cell culture spinner flasks
WO2003106661A3 (de) Glutaminfreies medium
ATE361108T1 (de) Verwendung eines hydrogels zum züchten von chondrozyten
WO2008073348A3 (en) Microgravity bioreactor systems for production of bioactive compounds and biological macromolecules
DK1495112T3 (da) Cellekulturmedium
WO2009007646A3 (fr) Systeme de production de microorganismes
WO2003089581A3 (en) A method to increase the rate of cell growth
EP0990704A3 (de) Nicht-reduzierende Saccharid-bildendes Enzym, Enzym das Trehalose freisetzt, und Verfahren zur Herstellung von Saccharide mittels diese Enzyme
WO2000070022A3 (en) Ex vivo expansion of mammalian hematopoietic stem cells
WO2003069972A3 (en) Hepatocyte precursor cell lines
AU4816201A (en) Production of tcr gamma delta t cells
ATE258594T1 (de) Verfahren zur steigerung des wachstums von pflanzenzellkulturen
WO2004033616A8 (de) Einrichtung zur kultivierung von zellen, insbesondere menschlicher oder tierischer zellen
TR200001960T2 (tr) Biyolojik ürünlerin üretimi için hücrelerin hazırlanması.
WO2024145139A3 (en) Systems and methods of biomass monitoring for cell culture bioreactors

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NI NO NZ OM PH PL PT RO RU SC SD SE SG SK SL TJ TM TN TR TT TZ UA UG US UZ VC VN YU ZA ZM ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZM ZW AM AZ BY KG KZ MD RU TJ TM AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LU MC NL PT RO SE SI SK TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG

DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
121 Ep: the epo has been informed by wipo that ep was designated in this application
WWE Wipo information: entry into national phase

Ref document number: 2003759889

Country of ref document: EP

WWP Wipo information: published in national office

Ref document number: 2003759889

Country of ref document: EP

NENP Non-entry into the national phase

Ref country code: JP

WWW Wipo information: withdrawn in national office

Country of ref document: JP