ATE361108T1 - Verwendung eines hydrogels zum züchten von chondrozyten - Google Patents
Verwendung eines hydrogels zum züchten von chondrozytenInfo
- Publication number
- ATE361108T1 ATE361108T1 AT04805394T AT04805394T ATE361108T1 AT E361108 T1 ATE361108 T1 AT E361108T1 AT 04805394 T AT04805394 T AT 04805394T AT 04805394 T AT04805394 T AT 04805394T AT E361108 T1 ATE361108 T1 AT E361108T1
- Authority
- AT
- Austria
- Prior art keywords
- chondrocytes
- hydrogel
- silanated
- complex
- grow
- Prior art date
Links
- 210000001612 chondrocyte Anatomy 0.000 title abstract 4
- 239000000017 hydrogel Substances 0.000 title abstract 2
- 229920000663 Hydroxyethyl cellulose Polymers 0.000 abstract 2
- 239000004354 Hydroxyethyl cellulose Substances 0.000 abstract 2
- 235000019447 hydroxyethyl cellulose Nutrition 0.000 abstract 2
- 239000001866 hydroxypropyl methyl cellulose Substances 0.000 abstract 2
- 229920003088 hydroxypropyl methyl cellulose Polymers 0.000 abstract 2
- 235000010979 hydroxypropyl methyl cellulose Nutrition 0.000 abstract 2
- UFVKGYZPFZQRLF-UHFFFAOYSA-N hydroxypropyl methyl cellulose Chemical compound OC1C(O)C(OC)OC(CO)C1OC1C(O)C(O)C(OC2C(C(O)C(OC3C(C(O)C(O)C(CO)O3)O)C(CO)O2)O)C(CO)O1 UFVKGYZPFZQRLF-UHFFFAOYSA-N 0.000 abstract 2
- 239000006177 biological buffer Substances 0.000 abstract 1
- 210000000845 cartilage Anatomy 0.000 abstract 1
- 210000004027 cell Anatomy 0.000 abstract 1
- 238000004132 cross linking Methods 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical class [H]* 0.000 abstract 1
- 238000001727 in vivo Methods 0.000 abstract 1
- 238000002347 injection Methods 0.000 abstract 1
- 239000007924 injection Substances 0.000 abstract 1
- 230000010354 integration Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0655—Chondrocytes; Cartilage
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
- A61L27/3817—Cartilage-forming cells, e.g. pre-chondrocytes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3839—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by the site of application in the body
- A61L27/3843—Connective tissue
- A61L27/3852—Cartilage, e.g. meniscus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3895—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells using specific culture conditions, e.g. stimulating differentiation of stem cells, pulsatile flow conditions
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2533/00—Supports or coatings for cell culture, characterised by material
- C12N2533/30—Synthetic polymers
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Cell Biology (AREA)
- Zoology (AREA)
- General Health & Medical Sciences (AREA)
- Rheumatology (AREA)
- Botany (AREA)
- Dermatology (AREA)
- Medicinal Chemistry (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Developmental Biology & Embryology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Materials For Medical Uses (AREA)
- Compositions Of Macromolecular Compounds (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP03292759A EP1529543A1 (de) | 2003-11-04 | 2003-11-04 | Verwendung eines hydrogels zur Chondrozyten-Kultur |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE361108T1 true ATE361108T1 (de) | 2007-05-15 |
Family
ID=34429548
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT04805394T ATE361108T1 (de) | 2003-11-04 | 2004-11-04 | Verwendung eines hydrogels zum züchten von chondrozyten |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US20070212389A1 (de) |
| EP (2) | EP1529543A1 (de) |
| JP (1) | JP4351258B2 (de) |
| CN (1) | CN100509064C (de) |
| AT (1) | ATE361108T1 (de) |
| AU (1) | AU2004287234B2 (de) |
| CA (1) | CA2543917A1 (de) |
| DE (1) | DE602004006299T2 (de) |
| DK (1) | DK1689461T5 (de) |
| ES (1) | ES2286709T3 (de) |
| PL (1) | PL1689461T3 (de) |
| WO (1) | WO2005044326A1 (de) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7622562B2 (en) | 2002-06-26 | 2009-11-24 | Zimmer Orthobiologics, Inc. | Rapid isolation of osteoinductive protein mixtures from mammalian bone tissue |
| EP2335650B1 (de) | 2003-12-11 | 2012-10-03 | Isto Technologies Inc. | Teilchenförmiges Knorpelsystem |
| WO2007025290A2 (en) | 2005-08-26 | 2007-03-01 | Isto Technologies, Inc. | Implants and methods for repair, replacement and treatment of joint disease |
| EP1764117A1 (de) * | 2005-09-20 | 2007-03-21 | Zimmer GmbH | Implantat zur Wiederherstellung von Knorpeldefekten und Verfahren zu seiner Herstellung |
| US8163549B2 (en) | 2006-12-20 | 2012-04-24 | Zimmer Orthobiologics, Inc. | Method of obtaining viable small tissue particles and use for tissue repair |
| EP2134297B1 (de) | 2007-04-12 | 2017-03-08 | Zimmer, Inc. | Vorrichtung zur gewebereparatur |
| WO2008136733A1 (en) * | 2007-05-04 | 2008-11-13 | Ascendia Ab | Method and means for culturing osteoblastic cells |
| WO2009057755A1 (ja) * | 2007-11-02 | 2009-05-07 | National Institute Of Advanced Industrial Science And Technology | 糖鎖アレイ基板とそれを用いた糖鎖結合分子検出法 |
| JP5544635B2 (ja) * | 2009-09-30 | 2014-07-09 | 国立大学法人北海道大学 | 軟骨細胞再分化誘導用基材およびこれを用いた軟骨細胞の製造方法 |
| US9414930B2 (en) * | 2010-10-26 | 2016-08-16 | Kyphon SÀRL | Activatable devices containing a chemonucleolysis agent |
| EP2714891B1 (de) | 2011-06-03 | 2019-11-13 | Institut National de la Sante et de la Recherche Medicale (INSERM) | Silyliertes biomolekülbasiertes hydrogel zur kultivierung von kardiomyozyten und stammzellen und verwendung des hydrogels davon zur behandlung von herzinsuffizienz |
| CN102775831B (zh) * | 2012-07-31 | 2014-11-12 | 华南理工大学 | 在材料表面紫外表固化接枝两性离子凝胶涂层的方法 |
| US20140178343A1 (en) | 2012-12-21 | 2014-06-26 | Jian Q. Yao | Supports and methods for promoting integration of cartilage tissue explants |
| WO2015084972A1 (en) * | 2013-12-03 | 2015-06-11 | Cornell University | Method of repairing an annulus and collagen gel composition |
| WO2016081742A1 (en) * | 2014-11-19 | 2016-05-26 | The Trustees Of Columbia University In The City Of New York | Systems, methods, and devices for cell cycle synchronization of stem cells |
| EP3167911A1 (de) * | 2015-11-10 | 2017-05-17 | Oniris | In si-hpmc-eingekapselte insulinerzeugende zellen zur behandlung von typ-1-diabetes |
| CN108102129B (zh) * | 2016-11-25 | 2021-01-01 | 山西加乐医疗科技有限责任公司 | 一种纤维素海绵的制备方法 |
| CN108042567A (zh) * | 2017-12-15 | 2018-05-18 | 广州金塞迩中西医结合医院有限公司 | 用于软骨修复的生物组合制剂及其应用 |
| CN109172604A (zh) * | 2018-08-08 | 2019-01-11 | 浙江大学 | 一种msc水凝胶复合物及应用 |
| CN114096660A (zh) * | 2019-04-08 | 2022-02-25 | Gn股份有限公司 | 高组织再生能力的软骨细胞培养物 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5902741A (en) * | 1986-04-18 | 1999-05-11 | Advanced Tissue Sciences, Inc. | Three-dimensional cartilage cultures |
| US5709854A (en) * | 1993-04-30 | 1998-01-20 | Massachusetts Institute Of Technology | Tissue formation by injecting a cell-polymeric solution that gels in vivo |
| US6129761A (en) * | 1995-06-07 | 2000-10-10 | Reprogenesis, Inc. | Injectable hydrogel compositions |
| FR2737663B1 (fr) * | 1995-08-07 | 1997-10-03 | Centre Nat Rech Scient | Composition pour bio-materiau, procede de preparation |
| FR2798671A1 (fr) * | 1999-09-16 | 2001-03-23 | Univ Paris Curie | Compositions de chondrocytes, preparation et utilisations |
-
2003
- 2003-11-04 EP EP03292759A patent/EP1529543A1/de not_active Withdrawn
-
2004
- 2004-11-04 CA CA002543917A patent/CA2543917A1/fr not_active Abandoned
- 2004-11-04 AU AU2004287234A patent/AU2004287234B2/en not_active Ceased
- 2004-11-04 ES ES04805394T patent/ES2286709T3/es not_active Expired - Lifetime
- 2004-11-04 AT AT04805394T patent/ATE361108T1/de active
- 2004-11-04 PL PL04805394T patent/PL1689461T3/pl unknown
- 2004-11-04 WO PCT/FR2004/002844 patent/WO2005044326A1/fr not_active Ceased
- 2004-11-04 CN CNB2004800383605A patent/CN100509064C/zh not_active Expired - Fee Related
- 2004-11-04 DE DE602004006299T patent/DE602004006299T2/de not_active Expired - Lifetime
- 2004-11-04 DK DK04805394T patent/DK1689461T5/da active
- 2004-11-04 US US10/577,942 patent/US20070212389A1/en not_active Abandoned
- 2004-11-04 EP EP04805394A patent/EP1689461B9/de not_active Expired - Lifetime
- 2004-11-04 JP JP2006537372A patent/JP4351258B2/ja not_active Expired - Fee Related
-
2010
- 2010-05-24 US US12/785,874 patent/US8440462B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP1689461B1 (de) | 2007-05-02 |
| EP1689461A1 (de) | 2006-08-16 |
| US20070212389A1 (en) | 2007-09-13 |
| CA2543917A1 (fr) | 2005-05-19 |
| WO2005044326A1 (fr) | 2005-05-19 |
| JP2007510410A (ja) | 2007-04-26 |
| PL1689461T3 (pl) | 2007-10-31 |
| US8440462B2 (en) | 2013-05-14 |
| EP1689461B9 (de) | 2007-08-29 |
| EP1529543A1 (de) | 2005-05-11 |
| DK1689461T5 (da) | 2007-10-15 |
| CN100509064C (zh) | 2009-07-08 |
| DE602004006299D1 (de) | 2007-06-14 |
| AU2004287234A1 (en) | 2005-05-19 |
| CN1897989A (zh) | 2007-01-17 |
| DE602004006299T2 (de) | 2008-04-10 |
| AU2004287234B2 (en) | 2010-08-05 |
| ES2286709T3 (es) | 2007-12-01 |
| DK1689461T3 (da) | 2007-09-10 |
| JP4351258B2 (ja) | 2009-10-28 |
| US20100297764A1 (en) | 2010-11-25 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
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