WO2004014946A1 - Nouvelle proteine homo avec fonction de suppression du cancer et sa sequence de codage - Google Patents

Nouvelle proteine homo avec fonction de suppression du cancer et sa sequence de codage Download PDF

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Publication number
WO2004014946A1
WO2004014946A1 PCT/CN2003/000639 CN0300639W WO2004014946A1 WO 2004014946 A1 WO2004014946 A1 WO 2004014946A1 CN 0300639 W CN0300639 W CN 0300639W WO 2004014946 A1 WO2004014946 A1 WO 2004014946A1
Authority
WO
WIPO (PCT)
Prior art keywords
suppressing function
polypeptide
cancer suppressing
coding sequence
homo protein
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/CN2003/000639
Other languages
English (en)
Chinese (zh)
Inventor
Shengli Yang
Jianren Gu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
NEWORGEN Ltd
Original Assignee
NEWORGEN Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CNB021364001A external-priority patent/CN100478354C/zh
Priority claimed from CNB021370001A external-priority patent/CN1229386C/zh
Priority claimed from CNB021370095A external-priority patent/CN1229387C/zh
Priority claimed from CNB021454353A external-priority patent/CN1222616C/zh
Application filed by NEWORGEN Ltd filed Critical NEWORGEN Ltd
Priority to AU2003255098A priority Critical patent/AU2003255098A1/en
Publication of WO2004014946A1 publication Critical patent/WO2004014946A1/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • C07K14/4703—Inhibitors; Suppressors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Cette invention se rapporte à un nouveau type de protéine HOMO avec fonction de suppression du cancer et à un polynucléotide codant ce polypeptide, ainsi qu'à un procédé pour produire ce polypeptide par des techniques de recombinaison. Cette invention concerne également un procédé utilisant ce polypeptide dans le traitement de divers types de maladies, tels que le cancer. L'antagoniste contre ce polypeptide et l'utilisation thérapeutique de ce polypeptide sont également décrits. Cette invention concerne en outre l'utilisation d'un polynucléotide codant cette protéine HOMO avec fonction de suppression du cancer.
PCT/CN2003/000639 2002-08-07 2003-08-07 Nouvelle proteine homo avec fonction de suppression du cancer et sa sequence de codage Ceased WO2004014946A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2003255098A AU2003255098A1 (en) 2002-08-07 2003-08-07 A novel homo protein with cancer suppressing function and its coding sequence

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
CNB021364001A CN100478354C (zh) 2002-08-07 2002-08-07 具有抑癌功能的新的人蛋白及其编码序列
CN02136400.1 2002-08-07
CNB021370001A CN1229386C (zh) 2002-09-16 2002-09-16 具有抑癌功能的新的人蛋白及其编码序列
CNB021370095A CN1229387C (zh) 2002-09-16 2002-09-16 具有抑癌功能的新的人蛋白及其编码序列
CN02137009.5 2002-09-16
CN02137000.1 2002-09-16
CNB021454353A CN1222616C (zh) 2002-11-20 2002-11-20 具有抑癌功能的新的人蛋白及其编码序列
CN02145435.3 2002-11-20

Publications (1)

Publication Number Publication Date
WO2004014946A1 true WO2004014946A1 (fr) 2004-02-19

Family

ID=31721565

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/CN2003/000639 Ceased WO2004014946A1 (fr) 2002-08-07 2003-08-07 Nouvelle proteine homo avec fonction de suppression du cancer et sa sequence de codage

Country Status (2)

Country Link
AU (1) AU2003255098A1 (fr)
WO (1) WO2004014946A1 (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2018234576A1 (fr) * 2017-06-22 2018-12-27 Institut Gustave Roussy Protéine rétrovirale endogène humaine
US20210214695A1 (en) * 2018-05-30 2021-07-15 Esteve Pharmaceuticals, S.A. Adenoassociated virus vectors for the treatment of mucopolysaccharidoses type iv a

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1313297A (zh) * 2000-03-09 2001-09-19 上海市肿瘤研究所 具有抑制癌细胞生长功能的新的人蛋白及其编码序列
CN1313298A (zh) * 2000-03-09 2001-09-19 上海市肿瘤研究所 具有抑制癌细胞生长功能的新的人蛋白及其编码序列
CN1323803A (zh) * 2000-05-15 2001-11-28 上海市肿瘤研究所 具有抑制癌细胞生长功能的新的人蛋白及其编码序列

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1313297A (zh) * 2000-03-09 2001-09-19 上海市肿瘤研究所 具有抑制癌细胞生长功能的新的人蛋白及其编码序列
CN1313298A (zh) * 2000-03-09 2001-09-19 上海市肿瘤研究所 具有抑制癌细胞生长功能的新的人蛋白及其编码序列
CN1323803A (zh) * 2000-05-15 2001-11-28 上海市肿瘤研究所 具有抑制癌细胞生长功能的新的人蛋白及其编码序列

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2018234576A1 (fr) * 2017-06-22 2018-12-27 Institut Gustave Roussy Protéine rétrovirale endogène humaine
US20210214695A1 (en) * 2018-05-30 2021-07-15 Esteve Pharmaceuticals, S.A. Adenoassociated virus vectors for the treatment of mucopolysaccharidoses type iv a
US12146169B2 (en) * 2018-05-30 2024-11-19 Esteve Pharmaceuticals, S.A. Adenoassociated virus vectors for the treatment of mucopolysaccharidoses type IV A
AU2019275969B2 (en) * 2018-05-30 2025-07-10 Esteve Pharmaceuticals, S.A. Adenoassociated virus vectors for the treatment of mucopolysaccharidoses type IV A

Also Published As

Publication number Publication date
AU2003255098A1 (en) 2004-02-25

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