WO2004085683A3 - Verfahren zur frühdiagnose von carcinomen und testkit zu dessen durchführung - Google Patents

Verfahren zur frühdiagnose von carcinomen und testkit zu dessen durchführung Download PDF

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Publication number
WO2004085683A3
WO2004085683A3 PCT/EP2004/003044 EP2004003044W WO2004085683A3 WO 2004085683 A3 WO2004085683 A3 WO 2004085683A3 EP 2004003044 W EP2004003044 W EP 2004003044W WO 2004085683 A3 WO2004085683 A3 WO 2004085683A3
Authority
WO
WIPO (PCT)
Prior art keywords
carrying
test kit
early carcinoma
carcinoma detection
papilloma virus
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/EP2004/003044
Other languages
English (en)
French (fr)
Other versions
WO2004085683A2 (de
Inventor
Ralf Hilfrich
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BUCHNER ERWIN
Original Assignee
BUCHNER ERWIN
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by BUCHNER ERWIN filed Critical BUCHNER ERWIN
Priority to JP2006504811A priority Critical patent/JP2006521104A/ja
Priority to EP04722574A priority patent/EP1656561A2/de
Publication of WO2004085683A2 publication Critical patent/WO2004085683A2/de
Publication of WO2004085683A3 publication Critical patent/WO2004085683A3/de
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701—Specific hybridization probes
    • C12Q1/708—Specific hybridization probes for papilloma
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Hospice & Palliative Care (AREA)
  • Virology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Die vorliegende Erfindung betrifft ein Verfahren zur frühen Diagnose von Carcinomen und ihren Vorstufen, die durch humane Papillomviren hervorgerufen werden oder eine Assoziation zu humanen Papillomviren aufweisen, anhand von Körperproben. In dem Verfahren wird bestimmt, ob ein virales Proteins der humanen Papillomviren exprimiert wird. Das virale Protein ist ein Capsidprotein, insbesondere das majore Capsidprotein Ll. Ausserdem betrifft die Erfindung ein Testkit zur Durchführung des Verfahrens.
PCT/EP2004/003044 2003-03-25 2004-03-23 Verfahren zur frühdiagnose von carcinomen und testkit zu dessen durchführung Ceased WO2004085683A2 (de)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP2006504811A JP2006521104A (ja) 2003-03-25 2004-03-23 癌腫の早期診断法及びこれを行うための検査キット
EP04722574A EP1656561A2 (de) 2003-03-25 2004-03-23 Verfahren zur frühdiagnose von carcinomen und testkit zu dessen durchführung

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10313388.7 2003-03-25
DE10313388 2003-03-25

Publications (2)

Publication Number Publication Date
WO2004085683A2 WO2004085683A2 (de) 2004-10-07
WO2004085683A3 true WO2004085683A3 (de) 2005-01-06

Family

ID=33038757

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2004/003044 Ceased WO2004085683A2 (de) 2003-03-25 2004-03-23 Verfahren zur frühdiagnose von carcinomen und testkit zu dessen durchführung

Country Status (3)

Country Link
EP (1) EP1656561A2 (de)
JP (1) JP2006521104A (de)
WO (1) WO2004085683A2 (de)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8859218B2 (en) 2008-06-13 2014-10-14 Oncohealth Corp. In situ detection of early stages and late stages HPV infection
US8916342B2 (en) 2006-11-13 2014-12-23 Oncohealth Corp. Identification of high grade or ≧ CIN2 for early stages and late stages detection, screening, and diagnosis of human papillomavirus (HPV) and HPV-associated cancers
US8968995B2 (en) 2008-11-12 2015-03-03 Oncohealth Corp. Detection, screening, and diagnosis of HPV-associated cancers
US9128094B2 (en) 2010-01-08 2015-09-08 Oncohealth Corp. High throughput cell-based HPV immunoassays for diagnosis and screening of HPV-associated cancers

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1936379A1 (de) * 2006-12-21 2008-06-25 BUCHNER, Erwin Verfahren zum Nachweis einer aktiven HPV-Infektion in biologischen Proben durch einen Sandwich-ELISA sowie Testkit zur Durchführung des Verfahrens
US9149517B2 (en) * 2007-11-02 2015-10-06 The Johns Hopkins University Multitype HPV peptide compositions and methods for treatment or prevention of human papillomavirus infection

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4332596A1 (de) * 1993-09-24 1995-03-30 Martin Josef Dr Sapp Monoklonale Antikörper
US5985610A (en) * 1992-09-03 1999-11-16 The United States Of America As Represented By The Department Of Health And Human Services Self-assembling recombinant papillomavirus capsid proteins
US6165471A (en) * 1997-07-03 2000-12-26 University Of Colorado, University Technology Corporation Homogeneous human papillomavirus capsomere containing compositions, methods for manufacture, and use thereof as diagnostic, prophylactic or therapeutic agents
WO2003020975A2 (en) * 2001-08-31 2003-03-13 Norchip A/S OLIGONUCLEOTIDES FOR USE IN DETECTION OF HUMAN PAPILLOMAVIRUS L1 mRNA

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5985610A (en) * 1992-09-03 1999-11-16 The United States Of America As Represented By The Department Of Health And Human Services Self-assembling recombinant papillomavirus capsid proteins
DE4332596A1 (de) * 1993-09-24 1995-03-30 Martin Josef Dr Sapp Monoklonale Antikörper
US6165471A (en) * 1997-07-03 2000-12-26 University Of Colorado, University Technology Corporation Homogeneous human papillomavirus capsomere containing compositions, methods for manufacture, and use thereof as diagnostic, prophylactic or therapeutic agents
WO2003020975A2 (en) * 2001-08-31 2003-03-13 Norchip A/S OLIGONUCLEOTIDES FOR USE IN DETECTION OF HUMAN PAPILLOMAVIRUS L1 mRNA

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
MCMURRAY H R ET AL: "Biology of human papillomaviruses", INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY, vol. 82, no. 1, February 2001 (2001-02-01), pages 15 - 33, XP002301425, ISSN: 0959-9673 *

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8916342B2 (en) 2006-11-13 2014-12-23 Oncohealth Corp. Identification of high grade or ≧ CIN2 for early stages and late stages detection, screening, and diagnosis of human papillomavirus (HPV) and HPV-associated cancers
US8859218B2 (en) 2008-06-13 2014-10-14 Oncohealth Corp. In situ detection of early stages and late stages HPV infection
US8865162B2 (en) 2008-06-13 2014-10-21 Oncohealth Corp. Monoclonal antibodies against HPV proteins
US9568474B2 (en) 2008-06-13 2017-02-14 Oncohealth Corp. In situ detection of early stages and late stages HPV infection
US8968995B2 (en) 2008-11-12 2015-03-03 Oncohealth Corp. Detection, screening, and diagnosis of HPV-associated cancers
US9128094B2 (en) 2010-01-08 2015-09-08 Oncohealth Corp. High throughput cell-based HPV immunoassays for diagnosis and screening of HPV-associated cancers

Also Published As

Publication number Publication date
EP1656561A2 (de) 2006-05-17
WO2004085683A2 (de) 2004-10-07
JP2006521104A (ja) 2006-09-21

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