ATE540319T1 - Verfahren für die bestimmung von fk506 - Google Patents

Verfahren für die bestimmung von fk506

Info

Publication number
ATE540319T1
ATE540319T1 AT04811367T AT04811367T ATE540319T1 AT E540319 T1 ATE540319 T1 AT E540319T1 AT 04811367 T AT04811367 T AT 04811367T AT 04811367 T AT04811367 T AT 04811367T AT E540319 T1 ATE540319 T1 AT E540319T1
Authority
AT
Austria
Prior art keywords
levels
determining
derivatives
blood
determination
Prior art date
Application number
AT04811367T
Other languages
English (en)
Inventor
Chengrong Wang
Tie Wei
Zhu Teng
Original Assignee
Siemens Healthcare Diagnostics
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Siemens Healthcare Diagnostics filed Critical Siemens Healthcare Diagnostics
Application granted granted Critical
Publication of ATE540319T1 publication Critical patent/ATE540319T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D498/18—Bridged systems
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/94—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
    • G01N33/9493—Immunosupressants
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/815—Test for named compound or class of compounds
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/825—Pretreatment for removal of interfering factors from sample

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Glass Compositions (AREA)
AT04811367T 2003-11-21 2004-11-10 Verfahren für die bestimmung von fk506 ATE540319T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/719,868 US7186518B2 (en) 2003-11-21 2003-11-21 Method and composition useful for determining FK 506
PCT/US2004/038640 WO2005052542A2 (en) 2003-11-21 2004-11-10 Method and composition useful for determining fk 506

Publications (1)

Publication Number Publication Date
ATE540319T1 true ATE540319T1 (de) 2012-01-15

Family

ID=34591451

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04811367T ATE540319T1 (de) 2003-11-21 2004-11-10 Verfahren für die bestimmung von fk506

Country Status (6)

Country Link
US (1) US7186518B2 (de)
EP (1) EP1687283B1 (de)
JP (1) JP4912887B2 (de)
AT (1) ATE540319T1 (de)
ES (1) ES2379959T3 (de)
WO (1) WO2005052542A2 (de)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7261735B2 (en) * 2001-05-07 2007-08-28 Cordis Corporation Local drug delivery devices and methods for maintaining the drug coatings thereon
US20060222756A1 (en) * 2000-09-29 2006-10-05 Cordis Corporation Medical devices, drug coatings and methods of maintaining the drug coatings thereon
WO2002026139A1 (en) 2000-09-29 2002-04-04 Cordis Corporation Coated medical devices
JP2007505932A (ja) * 2003-09-18 2007-03-15 マクサイト, インコーポレイテッド 経強膜送達
CA2597590A1 (en) 2005-02-09 2006-08-17 Macusight, Inc. Formulations for ocular treatment
US8663639B2 (en) * 2005-02-09 2014-03-04 Santen Pharmaceutical Co., Ltd. Formulations for treating ocular diseases and conditions
KR101478164B1 (ko) 2006-02-09 2014-12-31 산텐 세이야꾸 가부시키가이샤 안정한 제제와 그 제조 및 사용 방법
AU2007230964B2 (en) 2006-03-23 2012-07-19 Santen Pharmaceutical Co., Ltd. Formulations and methods for vascular permeability-related diseases or conditions
US8022188B2 (en) * 2006-04-24 2011-09-20 Abbott Laboratories Immunosuppressant binding antibodies and methods of obtaining and using same
US7642338B2 (en) * 2006-06-20 2010-01-05 Siemens Healthcare Diagnostics Inc. Tacrolimus standard and methods of using same
US7883855B2 (en) * 2006-07-21 2011-02-08 Abbott Laboratories Immunosuppressant drug extraction reagent for immunoassays
WO2008082984A2 (en) 2006-12-29 2008-07-10 Abbott Laboratories Non-denaturing lysis reagent for use with capture-in-solution immunoassay
ES2405364T3 (es) * 2006-12-29 2013-05-30 Abbott Laboratories Ensayo diagnóstico para la detección de una molécula o fármaco en sangre entera
ES2393135T3 (es) 2006-12-29 2012-12-18 Abbott Laboratories Ensayo mejorado para fármacos inmunosupresores
US7914999B2 (en) * 2006-12-29 2011-03-29 Abbott Laboratories Non-denaturing lysis reagent
US20080265343A1 (en) * 2007-04-26 2008-10-30 International Business Machines Corporation Field effect transistor with inverted t shaped gate electrode and methods for fabrication thereof
US7790401B2 (en) * 2007-08-06 2010-09-07 Siemens Healthcare Diagnostics Methods for detection of immunosuppressant drugs
US7910378B2 (en) 2007-12-14 2011-03-22 Siemens Healthcare Diagnostics Inc. Methods for detection of hydrophobic drugs
US8084223B2 (en) * 2009-03-23 2011-12-27 Siemens Healthcare Diagnostics Inc. Detection of false results in assays
US8809003B2 (en) 2010-06-25 2014-08-19 Siemens Healthcare Diagnostics Inc. Reduction in false results in assay measurements
US8329424B2 (en) 2010-06-25 2012-12-11 Siemens Healthcare Diagnostics Reduction in false results in assay measurements
US8563298B2 (en) 2010-10-22 2013-10-22 T2 Biosystems, Inc. NMR systems and methods for the rapid detection of analytes
EP3974831A1 (de) 2010-10-22 2022-03-30 T2 Biosystems, Inc. Verfahren zum nachweis eines bakteriums in einer vollblutprobe
US8409807B2 (en) 2010-10-22 2013-04-02 T2 Biosystems, Inc. NMR systems and methods for the rapid detection of analytes
US8586322B2 (en) 2012-03-07 2013-11-19 Siemens Healthcare Diagnostics, Inc Sandwich assay for immunosuppressant drugs
WO2013158281A1 (en) 2012-04-20 2013-10-24 T2 Biosystems, Inc. Compositions and methods for detection of candida species
US9658218B2 (en) * 2012-05-07 2017-05-23 Siemens Healthcare Diagnostics Inc. Determination of total analyte concentration
US9244083B2 (en) 2012-11-30 2016-01-26 Siemens Healthcare Diagnostics Inc. Compositions and methods for detecting vitamin D
US9121859B2 (en) 2012-12-04 2015-09-01 Siemens Healthcare Diagnostics Inc. Compounds and methods for determination of FKBP-binding immunosuppressant drugs
ES2740851T3 (es) 2013-12-13 2020-02-06 Siemens Healthcare Diagnostics Inc Agente de tratamiento previo en ensayos sin aglutinación
KR102309377B1 (ko) 2014-06-27 2021-10-05 지멘스 헬쓰케어 다이아그노스틱스 인크. 비타민 d 에피머에 특이적인 결합 파트너
KR20180021934A (ko) 2014-06-27 2018-03-05 지멘스 헬쓰케어 다이아그노스틱스 인크. 비타민 d 검정에서 비타민 d 에피머에 특이적인 결합 파트너
WO2016100116A1 (en) 2014-12-17 2016-06-23 Siemens Healthcare Diagnostics Inc. Sandwich assay design for small molecules
WO2017074703A1 (en) 2015-10-29 2017-05-04 Siemens Healthcare Diagnostics Inc. Sandwich assay for small molecules
US11519016B2 (en) 2016-01-21 2022-12-06 T2 Biosystems, Inc. NMR methods and systems for the rapid detection of bacteria
EP3873509B1 (de) * 2018-11-02 2024-06-12 Siemens Healthcare Diagnostics, Inc. Bindungskompetitoren zur verwendung in makrophilinbindenden pharmazeutischen assays und verfahren zur verwendung davon
EP3990923A4 (de) * 2019-06-28 2022-08-31 Siemens Healthcare Diagnostics, Inc. Reagenzien für sandwich-immunoassays unter verwendung von verbesserter agglutinationsdetektion mittels partikeln sowie verfahren zur herstellung und verwendung davon
CN115397464A (zh) 2020-04-24 2022-11-25 美国西门子医学诊断股份有限公司 用于使用抗人免疫球蛋白抗体的抗微生物血清学测定的组合物、试剂盒和方法

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4434236A (en) * 1982-10-20 1984-02-28 E. I. Du Pont De Nemours & Co. Immunoassay wherein labeled antibody is displaced from immobilized analyte-analogue
ES2060621T3 (es) * 1987-06-05 1994-12-01 Fujisawa Pharmaceutical Co Anticuerpos anti-sustancia fr-900506 y metodo de inmunoensayo enzimatico altamente sensible.
US5366971A (en) * 1987-11-09 1994-11-22 Sandoz Ltd. Use of 11,28-dioxa-4-azatricyclo[22.3.1.04,9 ]octacos-18-ene derivatives and pharmaceutical compositions containing them
PH26083A (en) * 1987-11-09 1992-02-06 Sandoz Ltd 11, 28-dioxa-4-azatricyclo [22.3.1.04.9) octacos-18-ene derivatives and pharmaceutical compositions containing them and method of use thereof
US5698448A (en) * 1988-12-02 1997-12-16 Soldin; Steven J. Immunosuppressive drug binding proteins and use
WO1991002736A1 (en) * 1989-08-18 1991-03-07 Fisons Plc Macrocyclic compounds
US5352671A (en) * 1989-11-09 1994-10-04 Sandoz Ltd. Heteroatoms-containing tricyclic compounds
JPH05504956A (ja) 1990-03-12 1993-07-29 藤沢薬品工業株式会社 トリシクロ化合物
WO1991017754A1 (en) * 1990-05-11 1991-11-28 Fujisawa Pharmaceutical Co., Ltd. Methods for treating and preventing inflammation of mucosa and blood vessels using fk 506 and related compounds
GB9014136D0 (en) * 1990-06-25 1990-08-15 Fujisawa Pharmaceutical Co Tricyclo compounds,a process for their production and a pharmaceutical composition containing the same
US5227304A (en) * 1991-01-16 1993-07-13 Sequoia Turner Corporation Method for counting whole blood diluent and detergent reagent system
WO1994024568A1 (en) * 1993-04-20 1994-10-27 Abbott Laboratories Stable aqueous fk506 standards
US5164495A (en) * 1991-09-18 1992-11-17 Abbott Laboratories Method for preparing a dicarboxylic acid half-acid ester of FK506
EP0672756B1 (de) * 1992-08-12 2002-02-13 Fujisawa Pharmaceutical Co., Ltd. Monoklonaler antikörper spezifisch für das fk-506-bindende protein, methode zur bestimmung des gehaltes an fk-506-bindendem protein in einer probe und reagenzsatz dafür
GB9318144D0 (en) * 1993-09-01 1993-10-20 Sandoz Ltd Organic compounds
US6187547B1 (en) * 1993-09-08 2001-02-13 Novartis Ag Assay kit
GB9318612D0 (en) 1993-09-08 1993-10-27 Sandoz Ltd An assay
US5373014A (en) * 1993-10-08 1994-12-13 American Home Products Corporation Rapamycin oximes
EP0729471A1 (de) * 1993-11-19 1996-09-04 Abbott Laboratories Semisynthetische rapamycin analoge mit immunomodulatorischer wirkung
AU686762B2 (en) * 1994-03-10 1998-02-12 Fujisawa Pharmaceutical Co., Ltd. Method for assaying immunosuppressant
US5635406A (en) * 1995-06-07 1997-06-03 Abbott Laboratories Stabilized standards and calibrators containing rapamycin and tacrolimus bound to anti-rapamycin and anti-tacrolimus antibodies
US5650288A (en) * 1995-07-14 1997-07-22 Macfarlane; Gordon D. Immunophilin-bound immunosuppressant assay
US5936401A (en) * 1996-09-19 1999-08-10 The United States Of America As Represented By The Secretary Of The Air Force Device and process for measuring electrical properties at a plurality of locations on thin film superconductors
GB9815696D0 (en) * 1998-07-20 1998-09-16 Pfizer Ltd Heterocyclics

Also Published As

Publication number Publication date
ES2379959T3 (es) 2012-05-07
JP4912887B2 (ja) 2012-04-11
WO2005052542A3 (en) 2005-12-01
JP2007512340A (ja) 2007-05-17
EP1687283B1 (de) 2012-01-04
US7186518B2 (en) 2007-03-06
US20050112778A1 (en) 2005-05-26
EP1687283A2 (de) 2006-08-09
EP1687283A4 (de) 2008-09-24
WO2005052542A2 (en) 2005-06-09

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