ATE540319T1 - Verfahren für die bestimmung von fk506 - Google Patents
Verfahren für die bestimmung von fk506Info
- Publication number
- ATE540319T1 ATE540319T1 AT04811367T AT04811367T ATE540319T1 AT E540319 T1 ATE540319 T1 AT E540319T1 AT 04811367 T AT04811367 T AT 04811367T AT 04811367 T AT04811367 T AT 04811367T AT E540319 T1 ATE540319 T1 AT E540319T1
- Authority
- AT
- Austria
- Prior art keywords
- levels
- determining
- derivatives
- blood
- determination
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- 239000008280 blood Substances 0.000 abstract 2
- 210000004369 blood Anatomy 0.000 abstract 2
- 102000014914 Carrier Proteins Human genes 0.000 abstract 1
- 238000003556 assay Methods 0.000 abstract 1
- 230000027455 binding Effects 0.000 abstract 1
- 108091008324 binding proteins Proteins 0.000 abstract 1
- 230000009870 specific binding Effects 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D498/18—Bridged systems
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/94—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
- G01N33/9493—Immunosupressants
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/815—Test for named compound or class of compounds
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/825—Pretreatment for removal of interfering factors from sample
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Cell Biology (AREA)
- Pharmacology & Pharmacy (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Glass Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/719,868 US7186518B2 (en) | 2003-11-21 | 2003-11-21 | Method and composition useful for determining FK 506 |
| PCT/US2004/038640 WO2005052542A2 (en) | 2003-11-21 | 2004-11-10 | Method and composition useful for determining fk 506 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE540319T1 true ATE540319T1 (de) | 2012-01-15 |
Family
ID=34591451
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT04811367T ATE540319T1 (de) | 2003-11-21 | 2004-11-10 | Verfahren für die bestimmung von fk506 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US7186518B2 (de) |
| EP (1) | EP1687283B1 (de) |
| JP (1) | JP4912887B2 (de) |
| AT (1) | ATE540319T1 (de) |
| ES (1) | ES2379959T3 (de) |
| WO (1) | WO2005052542A2 (de) |
Families Citing this family (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2424029C (en) | 2000-09-29 | 2008-01-29 | Cordis Corporation | Coated medical devices |
| US20060222756A1 (en) * | 2000-09-29 | 2006-10-05 | Cordis Corporation | Medical devices, drug coatings and methods of maintaining the drug coatings thereon |
| US7261735B2 (en) * | 2001-05-07 | 2007-08-28 | Cordis Corporation | Local drug delivery devices and methods for maintaining the drug coatings thereon |
| KR20060085246A (ko) * | 2003-09-18 | 2006-07-26 | 마커사이트, 인코포레이티드 | 경공막 전달 |
| DK1848431T3 (en) * | 2005-02-09 | 2016-04-18 | Santen Pharmaceutical Co Ltd | LIQUID FORMULATIONS FOR TREATMENT OF DISEASES OR CONDITIONS |
| US8663639B2 (en) * | 2005-02-09 | 2014-03-04 | Santen Pharmaceutical Co., Ltd. | Formulations for treating ocular diseases and conditions |
| KR20140093764A (ko) | 2006-02-09 | 2014-07-28 | 산텐 세이야꾸 가부시키가이샤 | 안정한 제제와 그 제조 및 사용 방법 |
| ES2563288T3 (es) | 2006-03-23 | 2016-03-14 | Santen Pharmaceutical Co., Ltd | Rapamicina en dosis bajas para el tratamiento de enfermedades relacionadas con la permeabilidad vascular |
| US8022188B2 (en) * | 2006-04-24 | 2011-09-20 | Abbott Laboratories | Immunosuppressant binding antibodies and methods of obtaining and using same |
| US7642338B2 (en) * | 2006-06-20 | 2010-01-05 | Siemens Healthcare Diagnostics Inc. | Tacrolimus standard and methods of using same |
| US7883855B2 (en) * | 2006-07-21 | 2011-02-08 | Abbott Laboratories | Immunosuppressant drug extraction reagent for immunoassays |
| WO2008082984A2 (en) | 2006-12-29 | 2008-07-10 | Abbott Laboratories | Non-denaturing lysis reagent for use with capture-in-solution immunoassay |
| ES2405364T3 (es) | 2006-12-29 | 2013-05-30 | Abbott Laboratories | Ensayo diagnóstico para la detección de una molécula o fármaco en sangre entera |
| EP2118656B1 (de) * | 2006-12-29 | 2012-08-29 | Abbott Laboratories | Verbessertes testverfahren für immunsuppressiva |
| US7914999B2 (en) * | 2006-12-29 | 2011-03-29 | Abbott Laboratories | Non-denaturing lysis reagent |
| US20080265343A1 (en) * | 2007-04-26 | 2008-10-30 | International Business Machines Corporation | Field effect transistor with inverted t shaped gate electrode and methods for fabrication thereof |
| US7790401B2 (en) * | 2007-08-06 | 2010-09-07 | Siemens Healthcare Diagnostics | Methods for detection of immunosuppressant drugs |
| US7910378B2 (en) * | 2007-12-14 | 2011-03-22 | Siemens Healthcare Diagnostics Inc. | Methods for detection of hydrophobic drugs |
| US8084223B2 (en) * | 2009-03-23 | 2011-12-27 | Siemens Healthcare Diagnostics Inc. | Detection of false results in assays |
| US8809003B2 (en) | 2010-06-25 | 2014-08-19 | Siemens Healthcare Diagnostics Inc. | Reduction in false results in assay measurements |
| US8329424B2 (en) | 2010-06-25 | 2012-12-11 | Siemens Healthcare Diagnostics | Reduction in false results in assay measurements |
| US8563298B2 (en) | 2010-10-22 | 2013-10-22 | T2 Biosystems, Inc. | NMR systems and methods for the rapid detection of analytes |
| CA2815085C (en) | 2010-10-22 | 2022-06-21 | T2 Biosystems, Inc. | Nmr systems and methods for the rapid detection of analytes |
| US8409807B2 (en) | 2010-10-22 | 2013-04-02 | T2 Biosystems, Inc. | NMR systems and methods for the rapid detection of analytes |
| US8586322B2 (en) | 2012-03-07 | 2013-11-19 | Siemens Healthcare Diagnostics, Inc | Sandwich assay for immunosuppressant drugs |
| EP2839038B1 (de) | 2012-04-20 | 2019-01-16 | T2 Biosystems, Inc. | Zusammensetzungen und verfahren für den nachweis einer candida-spezies |
| US9658218B2 (en) * | 2012-05-07 | 2017-05-23 | Siemens Healthcare Diagnostics Inc. | Determination of total analyte concentration |
| US9244083B2 (en) | 2012-11-30 | 2016-01-26 | Siemens Healthcare Diagnostics Inc. | Compositions and methods for detecting vitamin D |
| US9121859B2 (en) * | 2012-12-04 | 2015-09-01 | Siemens Healthcare Diagnostics Inc. | Compounds and methods for determination of FKBP-binding immunosuppressant drugs |
| ES2740851T3 (es) | 2013-12-13 | 2020-02-06 | Siemens Healthcare Diagnostics Inc | Agente de tratamiento previo en ensayos sin aglutinación |
| CN106661114B (zh) | 2014-06-27 | 2019-01-29 | 西门子医疗保健诊断公司 | 维生素d测定法中对维生素d差向异构体特异性的结合配偶体 |
| WO2015200182A1 (en) | 2014-06-27 | 2015-12-30 | Siemens Healthcare Diagnostics Inc. | Binding partners specific for vitamin d epimers |
| WO2016100116A1 (en) | 2014-12-17 | 2016-06-23 | Siemens Healthcare Diagnostics Inc. | Sandwich assay design for small molecules |
| US20180306828A1 (en) | 2015-10-29 | 2018-10-25 | Siemens Healthcare Diagnostics Inc. | Sandwich assay for small molecules |
| JP7523776B2 (ja) | 2016-01-21 | 2024-07-29 | ティー2 バイオシステムズ,インコーポレーテッド | 細菌を迅速に検出するnmr法及びシステム |
| ES2992864T3 (en) | 2018-11-02 | 2024-12-18 | Siemens Healthcare Diagnostics Inc | Binding competitors for use in macrophilin-binding pharmaceutical assays and methods of use thereof |
| US20220229049A1 (en) * | 2019-06-28 | 2022-07-21 | Siemens Healthcare Diagnostics Inc. | Reagents for sandwich immunoassays using particle enhanced agglutination detection and methods of production and use thereof |
| EP4138915A4 (de) | 2020-04-24 | 2024-04-24 | Siemens Healthcare Diagnostics, Inc. | Zusammensetzungen, kits und verfahren für antimikrobielle serologietests unter verwendung von anti-humanem immunglobulinantikörper |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4434236A (en) | 1982-10-20 | 1984-02-28 | E. I. Du Pont De Nemours & Co. | Immunoassay wherein labeled antibody is displaced from immobilized analyte-analogue |
| DE3886265T2 (de) | 1987-06-05 | 1994-04-28 | Fujisawa Pharmaceutical Co | Anti-FR-900506-Stoffe-Antikörper und höchstempfindliches Enzym-Immunoassay-Verfahren. |
| DK175235B1 (da) * | 1987-11-09 | 2004-07-19 | Novartis Ag | Ny anvendelse af azatricycloderivater og farmaceutiske præparater med indhold deraf |
| US5366971A (en) * | 1987-11-09 | 1994-11-22 | Sandoz Ltd. | Use of 11,28-dioxa-4-azatricyclo[22.3.1.04,9 ]octacos-18-ene derivatives and pharmaceutical compositions containing them |
| US5698448A (en) | 1988-12-02 | 1997-12-16 | Soldin; Steven J. | Immunosuppressive drug binding proteins and use |
| WO1991002736A1 (en) * | 1989-08-18 | 1991-03-07 | Fisons Plc | Macrocyclic compounds |
| US5352671A (en) | 1989-11-09 | 1994-10-04 | Sandoz Ltd. | Heteroatoms-containing tricyclic compounds |
| WO1991013899A1 (en) | 1990-03-12 | 1991-09-19 | Fujisawa Pharmaceutical Co., Ltd. | Tricyclo compounds |
| WO1991017754A1 (en) * | 1990-05-11 | 1991-11-28 | Fujisawa Pharmaceutical Co., Ltd. | Methods for treating and preventing inflammation of mucosa and blood vessels using fk 506 and related compounds |
| GB9014136D0 (en) * | 1990-06-25 | 1990-08-15 | Fujisawa Pharmaceutical Co | Tricyclo compounds,a process for their production and a pharmaceutical composition containing the same |
| US5227304A (en) | 1991-01-16 | 1993-07-13 | Sequoia Turner Corporation | Method for counting whole blood diluent and detergent reagent system |
| WO1994024568A1 (en) | 1993-04-20 | 1994-10-27 | Abbott Laboratories | Stable aqueous fk506 standards |
| US5164495A (en) * | 1991-09-18 | 1992-11-17 | Abbott Laboratories | Method for preparing a dicarboxylic acid half-acid ester of FK506 |
| ATE213272T1 (de) | 1992-08-12 | 2002-02-15 | Fujisawa Pharmaceutical Co | Monoklonaler antikörper spezifisch für das fk-506-bindende protein, methode zur bestimmung des gehaltes an fk-506-bindendem protein in einer probe und reagenzsatz dafür |
| GB9318144D0 (en) * | 1993-09-01 | 1993-10-20 | Sandoz Ltd | Organic compounds |
| GB9318612D0 (en) | 1993-09-08 | 1993-10-27 | Sandoz Ltd | An assay |
| US6187547B1 (en) | 1993-09-08 | 2001-02-13 | Novartis Ag | Assay kit |
| US5373014A (en) | 1993-10-08 | 1994-12-13 | American Home Products Corporation | Rapamycin oximes |
| CA2175215C (en) | 1993-11-19 | 2008-06-03 | Yat Sun Or | Semisynthetic analogs of rapamycin (macrolides) being immunomodulators |
| MX9603838A (es) * | 1994-03-10 | 1997-03-29 | Fujisawa Pharmaceutical Co | Metodo para ensayar inmunosupresores. |
| US5635406A (en) | 1995-06-07 | 1997-06-03 | Abbott Laboratories | Stabilized standards and calibrators containing rapamycin and tacrolimus bound to anti-rapamycin and anti-tacrolimus antibodies |
| US5650288A (en) | 1995-07-14 | 1997-07-22 | Macfarlane; Gordon D. | Immunophilin-bound immunosuppressant assay |
| US5936401A (en) * | 1996-09-19 | 1999-08-10 | The United States Of America As Represented By The Secretary Of The Air Force | Device and process for measuring electrical properties at a plurality of locations on thin film superconductors |
| GB9815696D0 (en) | 1998-07-20 | 1998-09-16 | Pfizer Ltd | Heterocyclics |
-
2003
- 2003-11-21 US US10/719,868 patent/US7186518B2/en not_active Expired - Lifetime
-
2004
- 2004-11-10 AT AT04811367T patent/ATE540319T1/de active
- 2004-11-10 WO PCT/US2004/038640 patent/WO2005052542A2/en not_active Ceased
- 2004-11-10 ES ES04811367T patent/ES2379959T3/es not_active Expired - Lifetime
- 2004-11-10 JP JP2006541358A patent/JP4912887B2/ja not_active Expired - Lifetime
- 2004-11-10 EP EP04811367A patent/EP1687283B1/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| WO2005052542A2 (en) | 2005-06-09 |
| JP4912887B2 (ja) | 2012-04-11 |
| JP2007512340A (ja) | 2007-05-17 |
| WO2005052542A3 (en) | 2005-12-01 |
| EP1687283B1 (de) | 2012-01-04 |
| EP1687283A2 (de) | 2006-08-09 |
| EP1687283A4 (de) | 2008-09-24 |
| ES2379959T3 (es) | 2012-05-07 |
| US7186518B2 (en) | 2007-03-06 |
| US20050112778A1 (en) | 2005-05-26 |
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