WO2004103155A3 - Diagnostic medical base sur une ionisation/desorption laser avec exaltation en surface - Google Patents

Diagnostic medical base sur une ionisation/desorption laser avec exaltation en surface Download PDF

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Publication number
WO2004103155A3
WO2004103155A3 PCT/US2004/015210 US2004015210W WO2004103155A3 WO 2004103155 A3 WO2004103155 A3 WO 2004103155A3 US 2004015210 W US2004015210 W US 2004015210W WO 2004103155 A3 WO2004103155 A3 WO 2004103155A3
Authority
WO
WIPO (PCT)
Prior art keywords
methods
laser desorption
disease diagnosis
ionization
enhanced laser
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2004/015210
Other languages
English (en)
Other versions
WO2004103155A2 (fr
Inventor
Rebecca E Caffrey
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aspira Womens Health Inc
Original Assignee
Ciphergen Biosystems Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciphergen Biosystems Inc filed Critical Ciphergen Biosystems Inc
Publication of WO2004103155A2 publication Critical patent/WO2004103155A2/fr
Anticipated expiration legal-status Critical
Publication of WO2004103155A3 publication Critical patent/WO2004103155A3/fr
Ceased legal-status Critical Current

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6848—Methods of protein analysis involving mass spectrometry
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6848—Methods of protein analysis involving mass spectrometry
    • G01N33/6851—Methods of protein analysis involving laser desorption ionisation mass spectrometry

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Hematology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Optics & Photonics (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)

Abstract

La présente invention se rapporte à des procédés permettant de faciliter un diagnostic ou un pronostic médical. Lesdits procédés consistent à capturer des anticorps dans des échantillons prélevés sur des sujets, et ce sur des sondes et au moyen d'antigènes qui sont indicateurs de maladies particulières. Ces procédés consistent également à détecter les anticorps capturés au moyen d'au moins une version d'une spectrométrie ionique en phase gazeuse à désorption/ionisation laser avec exaltation en surface. L'invention se rapporte en outre à des sondes et à des trousses permettant la mise en oeuvre des procédés décrits ci-dessus.
PCT/US2004/015210 2003-05-16 2004-05-14 Diagnostic medical base sur une ionisation/desorption laser avec exaltation en surface Ceased WO2004103155A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US47122903P 2003-05-16 2003-05-16
US60/471,229 2003-05-16

Publications (2)

Publication Number Publication Date
WO2004103155A2 WO2004103155A2 (fr) 2004-12-02
WO2004103155A3 true WO2004103155A3 (fr) 2007-12-06

Family

ID=33476813

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2004/015210 Ceased WO2004103155A2 (fr) 2003-05-16 2004-05-14 Diagnostic medical base sur une ionisation/desorption laser avec exaltation en surface

Country Status (1)

Country Link
WO (1) WO2004103155A2 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB202008887D0 (en) * 2020-06-11 2020-07-29 Binding Site Group Ltd A method of identifying or characterising an immune response in a subject

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6027942A (en) * 1993-05-28 2000-02-22 Baylor College Medicine Surface-enhanced affinity capture for desorption and detection or analytes

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6027942A (en) * 1993-05-28 2000-02-22 Baylor College Medicine Surface-enhanced affinity capture for desorption and detection or analytes

Also Published As

Publication number Publication date
WO2004103155A2 (fr) 2004-12-02

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