WO2004106491A8 - Therapies du vih-1 basees sur l'engiogenine - Google Patents

Therapies du vih-1 basees sur l'engiogenine

Info

Publication number
WO2004106491A8
WO2004106491A8 PCT/US2004/015781 US2004015781W WO2004106491A8 WO 2004106491 A8 WO2004106491 A8 WO 2004106491A8 US 2004015781 W US2004015781 W US 2004015781W WO 2004106491 A8 WO2004106491 A8 WO 2004106491A8
Authority
WO
WIPO (PCT)
Prior art keywords
hiv
replication
angiogenin
viruses
therapies
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2004/015781
Other languages
English (en)
Other versions
WO2004106491A2 (fr
WO2004106491A3 (fr
Inventor
Gene M Shearer
Maria T Rugeles
Susanna M Ryback
Joost J Oppenheim
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
US Department of Health and Human Services
Original Assignee
US Department of Health and Human Services
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by US Department of Health and Human Services filed Critical US Department of Health and Human Services
Publication of WO2004106491A2 publication Critical patent/WO2004106491A2/fr
Anticipated expiration legal-status Critical
Publication of WO2004106491A3 publication Critical patent/WO2004106491A3/fr
Publication of WO2004106491A8 publication Critical patent/WO2004106491A8/fr
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/1891—Angiogenesic factors; Angiogenin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Vascular Medicine (AREA)
  • Zoology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

L'invention concerne des méthodes de traitement de virus hautement mutants et de virus établissant des infections chroniques ou latentes chez un individu. En particulier, il est montré que l'engiogénine constitue un inhibiteur puissant de la réplication virale telle que pour le VIH-1. Ceci présente plusieurs avantages par rapport à d'autres ribonucléases connues lesquelles sont utilisées pour inhiber la réplication du VIH-1 étant donné que l'engiogénine inhibe la réplication du VIH-1 dans des cultures primaires de lymphocytes T activés et des lignées cellulaires infectées chroniquement. L'inhibition de la réplication du VIH-1 dans des lymphocytes T activés primaires augmenterait le risque de développement du VIH vers d'autres cellules sensibles.
PCT/US2004/015781 2003-05-22 2004-05-19 Therapies du vih-1 basees sur l'engiogenine Ceased WO2004106491A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US47296503P 2003-05-22 2003-05-22
US60/472,965 2003-05-22

Publications (3)

Publication Number Publication Date
WO2004106491A2 WO2004106491A2 (fr) 2004-12-09
WO2004106491A3 WO2004106491A3 (fr) 2006-08-24
WO2004106491A8 true WO2004106491A8 (fr) 2006-10-19

Family

ID=33490546

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2004/015781 Ceased WO2004106491A2 (fr) 2003-05-22 2004-05-19 Therapies du vih-1 basees sur l'engiogenine

Country Status (1)

Country Link
WO (1) WO2004106491A2 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2295969C1 (ru) * 2005-08-18 2007-03-27 Государственное учреждение Московский областной научно-исследовательский клинический институт им. М.Ф. Владимирского (МОНИКИ им. М.Ф. Владимирского) Способ стимуляции остеогенеза при переломах трубчатых костей

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2702645C (fr) * 2006-11-10 2018-01-02 Agriculture Victoria Services Pty Ltd Procede de preparation de l'angiogenine
CA2723987C (fr) 2008-05-14 2019-06-11 Agriculture Victoria Services Pty Ltd Utilisation de l'angiogenine ou d'agonistes de l'angiogenine pour traiter des maladies et des troubles
RU2010150934A (ru) * 2008-05-14 2012-06-20 Эгрикалчер Виктория Сервисиз Пти Лтд (Au) Пероральный препарат
AU2013204721B2 (en) * 2008-05-14 2016-08-18 Agriculture Victoria Services Pty Ltd Methods for treating cachexia
RU2429002C1 (ru) * 2010-09-13 2011-09-20 Государственное образовательное учреждение высшего профессионального образования "Курский государственный медицинский университет Федерального агентства по здравоохранению и социальному развитию" Способ стимуляции репаративного остеогенеза
AU2013204740C1 (en) 2012-05-10 2015-10-01 Agriculture Victoria Services Pty Ltd Methods of treating cancer using angiogenin or an angiogenin agonist

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2623509B1 (fr) * 1987-11-19 1990-04-20 Centre Nat Rech Scient Proteine de 17 kd a action angiogenique, son procede d'isolement a partir de lait de mammiferes, compositions therapeutiques la contenant, procede de detection et/ou de dosage et reactifs immunologiques de detection et de dosage des angiogenines de mammiferes, de leurs homologues et de leurs fragments
US4900673A (en) * 1988-03-28 1990-02-13 President And Fellows Of Harvard College Mutant human angiogenin (angiogenesis factor with superior angiogenin activity) genes therefor and methods of expression

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2295969C1 (ru) * 2005-08-18 2007-03-27 Государственное учреждение Московский областной научно-исследовательский клинический институт им. М.Ф. Владимирского (МОНИКИ им. М.Ф. Владимирского) Способ стимуляции остеогенеза при переломах трубчатых костей

Also Published As

Publication number Publication date
WO2004106491A2 (fr) 2004-12-09
WO2004106491A3 (fr) 2006-08-24

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