WO2004106548A3 - Verfahren zur snp-analyse auf biochips mit oligonukleotid-arealen - Google Patents

Verfahren zur snp-analyse auf biochips mit oligonukleotid-arealen Download PDF

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Publication number
WO2004106548A3
WO2004106548A3 PCT/EP2004/006002 EP2004006002W WO2004106548A3 WO 2004106548 A3 WO2004106548 A3 WO 2004106548A3 EP 2004006002 W EP2004006002 W EP 2004006002W WO 2004106548 A3 WO2004106548 A3 WO 2004106548A3
Authority
WO
WIPO (PCT)
Prior art keywords
nucleotide polymorphisms
biochips
snp
oligonucleotide
areas
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/EP2004/006002
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English (en)
French (fr)
Other versions
WO2004106548A2 (de
Inventor
Dirk Fischer
Joerg Geistlinger
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Institut fuer Pflanzengenetik und Kulturpflanzenforschung
Original Assignee
Institut fuer Pflanzengenetik und Kulturpflanzenforschung
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Institut fuer Pflanzengenetik und Kulturpflanzenforschung filed Critical Institut fuer Pflanzengenetik und Kulturpflanzenforschung
Priority to EP04739568A priority Critical patent/EP1629117A2/de
Publication of WO2004106548A2 publication Critical patent/WO2004106548A2/de
Publication of WO2004106548A3 publication Critical patent/WO2004106548A3/de
Priority to US11/293,048 priority patent/US20060127932A1/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
    • C12Q1/6837—Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

Die vorliegende Erfindung betrifft ein Verfahren zum multiparallelen Nachweis von Nukleotidpolymorphismen auf einem polydimensionalen Array. Des Weiteren betrifft die Erfindung ein Verfahren zum Nachweis vieler einzelner Nukleotidpolymorphismen, wobei die Nukleotidpolymorphismen multipler Individuen auf dem Array multiparallel nachgewiesen werden können. Im Rahmen des erfindungsgemässen Verfahrens erfolgt die Hybridisierung von jeweils einem Sondenmolekül mit jeweils einem Probenmolekül in einem Hybridisierungsfeld auf dem Array, das von umliegenden Hybridisierungsfeldern getrennt ist.
PCT/EP2004/006002 2003-06-03 2004-06-03 Verfahren zur snp-analyse auf biochips mit oligonukleotid-arealen Ceased WO2004106548A2 (de)

Priority Applications (2)

Application Number Priority Date Filing Date Title
EP04739568A EP1629117A2 (de) 2003-06-03 2004-06-03 Verfahren zur snp-analyse auf biochips mit oligonukleotid-arealen
US11/293,048 US20060127932A1 (en) 2003-06-03 2005-12-02 Method for the SNP analysis on biochips having oligonucleotide areas

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10325098A DE10325098B3 (de) 2003-06-03 2003-06-03 Verfahren zur SNP-Analyse auf Biochips mit Oligonukleotid-Arealen
DE10325098.0 2003-06-03

Related Child Applications (1)

Application Number Title Priority Date Filing Date
US11/293,048 Continuation US20060127932A1 (en) 2003-06-03 2005-12-02 Method for the SNP analysis on biochips having oligonucleotide areas

Publications (2)

Publication Number Publication Date
WO2004106548A2 WO2004106548A2 (de) 2004-12-09
WO2004106548A3 true WO2004106548A3 (de) 2005-02-10

Family

ID=33394800

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2004/006002 Ceased WO2004106548A2 (de) 2003-06-03 2004-06-03 Verfahren zur snp-analyse auf biochips mit oligonukleotid-arealen

Country Status (4)

Country Link
US (1) US20060127932A1 (de)
EP (1) EP1629117A2 (de)
DE (1) DE10325098B3 (de)
WO (1) WO2004106548A2 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102004025269A1 (de) * 2004-05-19 2005-09-15 Infineon Technologies Ag Biochipzelle mit Biochipsubstrat und Abdeckung für Aufnahme und optische Analyse biologischer Proben und Verfahren zur Präparation und Durchführung der Analyse
CN109337805A (zh) * 2018-09-28 2019-02-15 泰普生物科学（中国）有限公司 一种生物芯片杂交装置
CN115678979B (zh) * 2022-04-04 2023-12-22 中国热带农业科学院南亚热带作物研究所 菠萝液相芯片及其应用
CN119639948B (zh) * 2025-01-06 2025-07-11 沈阳农业大学 一种与梨果实果皮颜色相关的snp分子标记及应用

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997035033A1 (en) * 1996-03-19 1997-09-25 Molecular Tool, Inc. Method for determining the nucleotide sequence of a polynucleotide
WO2004031406A2 (de) * 2002-09-27 2004-04-15 Array-On Gmbh VERFAHREN ZUM NACHWEIS VON SNPs AUF POLYDIMENSIONALEN MICROARRAYS

Family Cites Families (5)

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Publication number Priority date Publication date Assignee Title
GB9507238D0 (en) * 1995-04-07 1995-05-31 Isis Innovation Detecting dna sequence variations
AUPO427996A0 (en) * 1996-12-20 1997-01-23 Co-Operative Research Centre For Diagnostic Technologies Method for detecting a nucleotide at a specific location within a polynucleotide sequence and apparatus therefor
US6465178B2 (en) * 1997-09-30 2002-10-15 Surmodics, Inc. Target molecule attachment to surfaces
US6238869B1 (en) * 1997-12-19 2001-05-29 High Throughput Genomics, Inc. High throughput assay system
US6235483B1 (en) * 2000-01-31 2001-05-22 Agilent Technologies, Inc. Methods and kits for indirect labeling of nucleic acids

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997035033A1 (en) * 1996-03-19 1997-09-25 Molecular Tool, Inc. Method for determining the nucleotide sequence of a polynucleotide
WO2004031406A2 (de) * 2002-09-27 2004-04-15 Array-On Gmbh VERFAHREN ZUM NACHWEIS VON SNPs AUF POLYDIMENSIONALEN MICROARRAYS

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
GUO Z ET AL: "DIRECT FLUORESCENCE ANALYSIS OF GENETIC POLYMORPHISMS BY HYBRIDIZATION WITH OLIGONUCLEOTIDE ARRAYS ON GLASS SUPPORTS", NUCLEIC ACIDS RESEARCH, OXFORD UNIVERSITY PRESS, SURREY, GB, vol. 22, no. 24, 1994, pages 5456 - 5465, XP008018942, ISSN: 0305-1048 *
JALANKO A ET AL: "SCREENING FOR DEFINED CYSTIC FIBROSIS MUTATIONS BY SOLID-PHASE MINISEQUENCING", CLINICAL CHEMISTRY, AMERICAN ASSOCIATION FOR CLINICAL CHEMISTRY. WINSTON, US, vol. 38, no. 1, 1992, pages 39 - 43, XP001105344, ISSN: 0009-9147 *
NIKIFOROV T T ET AL: "GENETIC BIT ANALYSIS: A SOLID PHASE METHOD FOR TYPING SINGLE NUCLEOTIDE POLYMORPHISMS", NUCLEIC ACIDS RESEARCH, OXFORD UNIVERSITY PRESS, SURREY, GB, vol. 22, no. 20, January 1994 (1994-01-01), pages 4167 - 4175, XP000606174, ISSN: 0305-1048 *
PASTINEN T ET AL: "A SYSTEM FOR SPECIFIC, HIGH-THROUGPUT GENOTYPING BY ALLELE-SPECIFIC PRIMER EXTENSION ON MICROARRAYS", GENOME RESEARCH, COLD SPRING HARBOR LABORATORY PRESS, US, vol. 10, no. 7, July 2000 (2000-07-01), pages 1031 - 1042, XP008013561, ISSN: 1088-9051 *
SHUMAKER J M ET AL: "MUTATION DETECTION BY SOLID PHASE PRIMER EXTENSION", HUMAN MUTATION, WILEY-LISS, NEW YORK, NY, US, vol. 7, 1996, pages 346 - 354, XP001073481, ISSN: 1059-7794 *

Also Published As

Publication number Publication date
WO2004106548A2 (de) 2004-12-09
DE10325098B3 (de) 2004-12-02
US20060127932A1 (en) 2006-06-15
EP1629117A2 (de) 2006-03-01

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